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The map label for this gene is phoP [H]

Identifier: 37522708

GI number: 37522708

Start: 3341792

End: 3342481

Strand: Direct

Name: phoP [H]

Synonym: glr3139

Alternate gene names: 37522708

Gene position: 3341792-3342481 (Clockwise)

Preceding gene: 37522707

Following gene: 37522709

Centisome position: 71.73

GC content: 60.87

Gene sequence:

>690_bases
ATGAACAACCCCATTTTGGTCGTTGAGGACGACGAGACCCTGGCGCAGGTGCTGCGCAAGACCCTCGAATCGGAAGGCTA
CACGGTGACGCTCGCCCGCGACGGCCGCGCTGCTTTGGAGTTGGGCCGCGAGCCGGGATTGCAGCTCATCATTCTCGACT
TGATGCTGCCGCGCATGAGCGGGCTGGAAGTTTGCCAACGCCTGCGCTCCGAGAACGTCGTCACACCGATCATCATGCTG
ACTGCCCGCGGCCTGGATACCGACAAGGTCTTCGGCCTGCGGCTCGGGGCGGACGATTACCTCAGCAAACCTTTTAACAT
CGATGAATTGCTGGCCCGCATTGAGGCGGTCCTGCGCCGCACCCACCAGAGCAAACCTTCCCAACACGTGAGCGTAGGGG
ACCTGGAGATCGATTTTCAGCGCCTGAGCGTCTGCAAAAACCGCCAAAAGCTCGATCTCTCCTCGCGGGAATTCCAGGTG
CTCGAGTGTCTGTTTCGCAGCGCCGGACAGACGGTGGACCGCGAAAAGATTTACCAGGAAGTCTGGGGCTACGACACCGC
CGTCACCAACCGCACCATCGACTTTCACATCGCCCGGCTGCGCTCCAAGCTCGAAGACAACCCCAAAGAACCGCGCTATA
TCCTCACGGTGCATGGCTCCGGGTACCGGTTCGTGGTGCCGGAGGTGTGA

Upstream 100 bases:

>100_bases
GGGCTGGCCATCGCTTCGCAGATCGTCAATGCCCACCGCGGCCAGATACTGGTCGAAAGCCGCGTCGGTATCGGCAGCAC
ATTCACCGTGAAGATTCCCC

Downstream 100 bases:

>100_bases
GTGCTCTCACCTCTTTCTTTTTCCCGATGACGGCACGGCCGCCGTTCCGTAGGATGCACGGGTAAGCTTCAGCGGGAGCA
ACCTATGGCAATTGCAATCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNNPILVVEDDETLAQVLRKTLESEGYTVTLARDGRAALELGREPGLQLIILDLMLPRMSGLEVCQRLRSENVVTPIIML
TARGLDTDKVFGLRLGADDYLSKPFNIDELLARIEAVLRRTHQSKPSQHVSVGDLEIDFQRLSVCKNRQKLDLSSREFQV
LECLFRSAGQTVDREKIYQEVWGYDTAVTNRTIDFHIARLRSKLEDNPKEPRYILTVHGSGYRFVVPEV

Sequences:

>Translated_229_residues
MNNPILVVEDDETLAQVLRKTLESEGYTVTLARDGRAALELGREPGLQLIILDLMLPRMSGLEVCQRLRSENVVTPIIML
TARGLDTDKVFGLRLGADDYLSKPFNIDELLARIEAVLRRTHQSKPSQHVSVGDLEIDFQRLSVCKNRQKLDLSSREFQV
LECLFRSAGQTVDREKIYQEVWGYDTAVTNRTIDFHIARLRSKLEDNPKEPRYILTVHGSGYRFVVPEV
>Mature_229_residues
MNNPILVVEDDETLAQVLRKTLESEGYTVTLARDGRAALELGREPGLQLIILDLMLPRMSGLEVCQRLRSENVVTPIIML
TARGLDTDKVFGLRLGADDYLSKPFNIDELLARIEAVLRRTHQSKPSQHVSVGDLEIDFQRLSVCKNRQKLDLSSREFQV
LECLFRSAGQTVDREKIYQEVWGYDTAVTNRTIDFHIARLRSKLEDNPKEPRYILTVHGSGYRFVVPEV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=39.5652173913043, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=42.1739130434783, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=37.6106194690265, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=39.3665158371041, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=39.647577092511, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=38.1578947368421, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=37.117903930131, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=35.3211009174312, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=33.7899543378995, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=32.9059829059829, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=31.1965811965812, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=28.8135593220339, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790437, Length=121, Percent_Identity=37.1900826446281, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=29.1925465838509, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=39.2156862745098, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=114, Percent_Identity=38.5964912280702, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=123, Percent_Identity=31.7073170731707, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=106, Percent_Identity=33.0188679245283, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26124; Mature: 26124

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPILVVEDDETLAQVLRKTLESEGYTVTLARDGRAALELGREPGLQLIILDLMLPRMS
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEHHHHHHCCCC
GLEVCQRLRSENVVTPIIMLTARGLDTDKVFGLRLGADDYLSKPFNIDELLARIEAVLRR
HHHHHHHHHHCCCCCHHHEEEECCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHH
THQSKPSQHVSVGDLEIDFQRLSVCKNRQKLDLSSREFQVLECLFRSAGQTVDREKIYQE
HHCCCCCCCEEECCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
VWGYDTAVTNRTIDFHIARLRSKLEDNPKEPRYILTVHGSGYRFVVPEV
HHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCC
>Mature Secondary Structure
MNNPILVVEDDETLAQVLRKTLESEGYTVTLARDGRAALELGREPGLQLIILDLMLPRMS
CCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEHHHHHHCCCC
GLEVCQRLRSENVVTPIIMLTARGLDTDKVFGLRLGADDYLSKPFNIDELLARIEAVLRR
HHHHHHHHHHCCCCCHHHEEEECCCCCCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHH
THQSKPSQHVSVGDLEIDFQRLSVCKNRQKLDLSSREFQVLECLFRSAGQTVDREKIYQE
HHCCCCCCCEEECCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHH
VWGYDTAVTNRTIDFHIARLRSKLEDNPKEPRYILTVHGSGYRFVVPEV
HHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]