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The map label for this gene is rprX [H]

Identifier: 37522707

GI number: 37522707

Start: 3340069

End: 3341817

Strand: Direct

Name: rprX [H]

Synonym: glr3138

Alternate gene names: 37522707

Gene position: 3340069-3341817 (Clockwise)

Preceding gene: 37522705

Following gene: 37522708

Centisome position: 71.69

GC content: 58.6

Gene sequence:

>1749_bases
ATGAGCAAGATCACTTCTGCAATCGAAAAGCGTTTTTATGCGGCCATCCAATGGAGCCTCAAACACCAGTTGAAGGCGAT
GGCGATTATTTTGCTGGGGGTGATCGTCCCCATCGGCACGCTCAATGTGCTGCAGTATCAATCGATGGTCCAGTACGAGC
AACAGGGAACCCGAGCCCTGCAAGAGCAGATGCAGAGCCTGCTCGGCCGTATGGCGCTGAGAATTTATACCGACACCTAT
CGGGGATTTCACGACACTTTTCATTCGGTAGATCGCGAACACAACGAGCTATTTAGCGGCAAACCCAGGATCGCAAGCAC
GCTCGTGGGTGCGATCCAGAACACCAGCAACAGCTACACGGCAAAGAAAAAAAAGCCACAGCAGGCGCTGTTTATCTTTG
CAAAAGAACCCGACGGCACCTGGAAATCCTATTTTGGCCGCAGCAACAGCGACAATCCGGCGCGGCGCGCGGCAGCGGCC
CGCGCCCGAGAATACTTTTTCACCTTGCCGCCGGAGCGGCAGGACACCGGCCATCAGTACTACTACGACGCCGAAAGCGA
AATGCTGGTGCTGCTGCACACGATGTCCCCGGCCCAAATCGTCTATTCCGACACCCCCCCCCTGCGTCCGATCAAAGCGG
TCATGGGTGTCACTTTGACCAAGAAAGATTTCAAGGACGACTTCAAATACCAGACCCAGACCGGAGCGATCAGCCGCTTC
GATACCACGCCCCTCGATTCGCAACTGGCCGGCACGACCTACTACTACCAGGTCAAAGACGAAAAGGGGCAGGTGCTCTA
CAAAGATCCCGGTTGGGATAAAAACGTCGGTTGCAACGACTTTATCCGCGCCGATTTTCGGATCACCCCTGAGCAGCGCT
TTTTGACCGATTGGGAGCTTTCGGCGATCACCCGCAGCAACTTCAAGCAGGCCACCGAGCGCAGCCTCACCCAGATGTTC
TGGGCGAGCGGCATCGTCGCAGTGCTGTTGGGGATGTTGCTGGTGGTCCTCTTTCGGGCCGGGCTGGTGGCGGTCAAAGT
CTCCGAGTTGCAGACCGACATCGTGGCGGGGGTCTCCCACGACCTGAAGACGCCGCTGGCCGGAATCATCGCCTCCGCCC
AGCTGATCGCCTCGGGACGCGCGAGCGGCGTTCAGGAAACCAAACAATTTTCCGGCTACATCCTGGCCGAAGCGCGGCGG
CTCACCGCGGTGGTCGAGAAGGTACTGACGATGGCCAAGCTCGAATCGCGCCAGTTGCTGATGAAACCTTCGCCCCTCAG
TGTTGCGGAACTGATTGACCACGCCATCGGTCTGTCGCAGGCGGCCTACCCGCAGGCAATTATCGCCAAGGGTGAAGTGG
CCACCGGCCAGGTCACAGGCGACGCCAACGCCCTCACTACGGTGCTGATGAATCTGATCGACAATGCCGTGCGCTACTCA
GGCGACGCCCAGCCCTGGGTGCGGGTGCAGTCCTACTGGAGCGGCTTTGGTGAGAAGCGGATATTGCATCTGTTGGTCGA
GGACCGGGGTGTGGGTATCCCGGCCGAGGAGCAGGCGTTTATCTTTCAGAAATTTTACCGGGTGCGCAACGGCCTGGTAA
GCGATACCGAGGGGACCGGGCTGGGGCTGGCCATCGCTTCGCAGATCGTCAATGCCCACCGCGGCCAGATACTGGTCGAA
AGCCGCGTCGGTATCGGCAGCACATTCACCGTGAAGATTCCCCATGAACAACCCCATTTTGGTCGTTGA

Upstream 100 bases:

>100_bases
TGTGCGAGAGGCCGAATGCAACCGCTCATCGCGACTCATAAAATCTCACATCTGGAGTGGGATCGATGGGTTATCCTGAC
GACTAACGGGATCCACACCG

Downstream 100 bases:

>100_bases
GGACGACGAGACCCTGGCGCAGGTGCTGCGCAAGACCCTCGAATCGGAAGGCTACACGGTGACGCTCGCCCGCGACGGCC
GCGCTGCTTTGGAGTTGGGC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MSKITSAIEKRFYAAIQWSLKHQLKAMAIILLGVIVPIGTLNVLQYQSMVQYEQQGTRALQEQMQSLLGRMALRIYTDTY
RGFHDTFHSVDREHNELFSGKPRIASTLVGAIQNTSNSYTAKKKKPQQALFIFAKEPDGTWKSYFGRSNSDNPARRAAAA
RAREYFFTLPPERQDTGHQYYYDAESEMLVLLHTMSPAQIVYSDTPPLRPIKAVMGVTLTKKDFKDDFKYQTQTGAISRF
DTTPLDSQLAGTTYYYQVKDEKGQVLYKDPGWDKNVGCNDFIRADFRITPEQRFLTDWELSAITRSNFKQATERSLTQMF
WASGIVAVLLGMLLVVLFRAGLVAVKVSELQTDIVAGVSHDLKTPLAGIIASAQLIASGRASGVQETKQFSGYILAEARR
LTAVVEKVLTMAKLESRQLLMKPSPLSVAELIDHAIGLSQAAYPQAIIAKGEVATGQVTGDANALTTVLMNLIDNAVRYS
GDAQPWVRVQSYWSGFGEKRILHLLVEDRGVGIPAEEQAFIFQKFYRVRNGLVSDTEGTGLGLAIASQIVNAHRGQILVE
SRVGIGSTFTVKIPHEQPHFGR

Sequences:

>Translated_582_residues
MSKITSAIEKRFYAAIQWSLKHQLKAMAIILLGVIVPIGTLNVLQYQSMVQYEQQGTRALQEQMQSLLGRMALRIYTDTY
RGFHDTFHSVDREHNELFSGKPRIASTLVGAIQNTSNSYTAKKKKPQQALFIFAKEPDGTWKSYFGRSNSDNPARRAAAA
RAREYFFTLPPERQDTGHQYYYDAESEMLVLLHTMSPAQIVYSDTPPLRPIKAVMGVTLTKKDFKDDFKYQTQTGAISRF
DTTPLDSQLAGTTYYYQVKDEKGQVLYKDPGWDKNVGCNDFIRADFRITPEQRFLTDWELSAITRSNFKQATERSLTQMF
WASGIVAVLLGMLLVVLFRAGLVAVKVSELQTDIVAGVSHDLKTPLAGIIASAQLIASGRASGVQETKQFSGYILAEARR
LTAVVEKVLTMAKLESRQLLMKPSPLSVAELIDHAIGLSQAAYPQAIIAKGEVATGQVTGDANALTTVLMNLIDNAVRYS
GDAQPWVRVQSYWSGFGEKRILHLLVEDRGVGIPAEEQAFIFQKFYRVRNGLVSDTEGTGLGLAIASQIVNAHRGQILVE
SRVGIGSTFTVKIPHEQPHFGR
>Mature_581_residues
SKITSAIEKRFYAAIQWSLKHQLKAMAIILLGVIVPIGTLNVLQYQSMVQYEQQGTRALQEQMQSLLGRMALRIYTDTYR
GFHDTFHSVDREHNELFSGKPRIASTLVGAIQNTSNSYTAKKKKPQQALFIFAKEPDGTWKSYFGRSNSDNPARRAAAAR
AREYFFTLPPERQDTGHQYYYDAESEMLVLLHTMSPAQIVYSDTPPLRPIKAVMGVTLTKKDFKDDFKYQTQTGAISRFD
TTPLDSQLAGTTYYYQVKDEKGQVLYKDPGWDKNVGCNDFIRADFRITPEQRFLTDWELSAITRSNFKQATERSLTQMFW
ASGIVAVLLGMLLVVLFRAGLVAVKVSELQTDIVAGVSHDLKTPLAGIIASAQLIASGRASGVQETKQFSGYILAEARRL
TAVVEKVLTMAKLESRQLLMKPSPLSVAELIDHAIGLSQAAYPQAIIAKGEVATGQVTGDANALTTVLMNLIDNAVRYSG
DAQPWVRVQSYWSGFGEKRILHLLVEDRGVGIPAEEQAFIFQKFYRVRNGLVSDTEGTGLGLAIASQIVNAHRGQILVES
RVGIGSTFTVKIPHEQPHFGR

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=30.327868852459, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=30.4721030042918, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=26.0869565217391, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=28.6324786324786, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=33.9285714285714, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=28, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=240, Percent_Identity=25.4166666666667, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=27.8761061946903, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=26.9911504424779, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=27.1929824561404, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=27.1966527196653, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788393, Length=238, Percent_Identity=26.0504201680672, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=26.9565217391304, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=230, Percent_Identity=26.9565217391304, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=27.0642201834862, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=27.1028037383178, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64792; Mature: 64661

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKITSAIEKRFYAAIQWSLKHQLKAMAIILLGVIVPIGTLNVLQYQSMVQYEQQGTRAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QEQMQSLLGRMALRIYTDTYRGFHDTFHSVDREHNELFSGKPRIASTLVGAIQNTSNSYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
AKKKKPQQALFIFAKEPDGTWKSYFGRSNSDNPARRAAAARAREYFFTLPPERQDTGHQY
CCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCEE
YYDAESEMLVLLHTMSPAQIVYSDTPPLRPIKAVMGVTLTKKDFKDDFKYQTQTGAISRF
EEECCCCEEEEEEECCCCEEEECCCCCCHHHHHHHCCCCCHHHHHHHHCEECCCCCCEEC
DTTPLDSQLAGTTYYYQVKDEKGQVLYKDPGWDKNVGCNDFIRADFRITPEQRFLTDWEL
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHEECCEEECCHHHHCCCHHH
SAITRSNFKQATERSLTQMFWASGIVAVLLGMLLVVLFRAGLVAVKVSELQTDIVAGVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHCCH
DLKTPLAGIIASAQLIASGRASGVQETKQFSGYILAEARRLTAVVEKVLTMAKLESRQLL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHE
MKPSPLSVAELIDHAIGLSQAAYPQAIIAKGEVATGQVTGDANALTTVLMNLIDNAVRYS
ECCCCCCHHHHHHHHHCCCCCCCCHHHEECCCCCCCEECCCHHHHHHHHHHHHHHHHHCC
GDAQPWVRVQSYWSGFGEKRILHLLVEDRGVGIPAEEQAFIFQKFYRVRNGLVSDTEGTG
CCCCHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAIASQIVNAHRGQILVESRVGIGSTFTVKIPHEQPHFGR
HHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SKITSAIEKRFYAAIQWSLKHQLKAMAIILLGVIVPIGTLNVLQYQSMVQYEQQGTRAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
QEQMQSLLGRMALRIYTDTYRGFHDTFHSVDREHNELFSGKPRIASTLVGAIQNTSNSYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
AKKKKPQQALFIFAKEPDGTWKSYFGRSNSDNPARRAAAARAREYFFTLPPERQDTGHQY
CCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCEE
YYDAESEMLVLLHTMSPAQIVYSDTPPLRPIKAVMGVTLTKKDFKDDFKYQTQTGAISRF
EEECCCCEEEEEEECCCCEEEECCCCCCHHHHHHHCCCCCHHHHHHHHCEECCCCCCEEC
DTTPLDSQLAGTTYYYQVKDEKGQVLYKDPGWDKNVGCNDFIRADFRITPEQRFLTDWEL
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCCCCCCCCHHEECCEEECCHHHHCCCHHH
SAITRSNFKQATERSLTQMFWASGIVAVLLGMLLVVLFRAGLVAVKVSELQTDIVAGVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHCCH
DLKTPLAGIIASAQLIASGRASGVQETKQFSGYILAEARRLTAVVEKVLTMAKLESRQLL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHE
MKPSPLSVAELIDHAIGLSQAAYPQAIIAKGEVATGQVTGDANALTTVLMNLIDNAVRYS
ECCCCCCHHHHHHHHHCCCCCCCCHHHEECCCCCCCEECCCHHHHHHHHHHHHHHHHHCC
GDAQPWVRVQSYWSGFGEKRILHLLVEDRGVGIPAEEQAFIFQKFYRVRNGLVSDTEGTG
CCCCHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
LGLAIASQIVNAHRGQILVESRVGIGSTFTVKIPHEQPHFGR
HHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]