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The map label for this gene is murA

Identifier: 37522694

GI number: 37522694

Start: 3327941

End: 3329320

Strand: Direct

Name: murA

Synonym: glr3125

Alternate gene names: 37522694

Gene position: 3327941-3329320 (Clockwise)

Preceding gene: 37522693

Following gene: 37522697

Centisome position: 71.43

GC content: 66.67

Gene sequence:

>1380_bases
ATGGGAATCGAGCCTTCCCTGCCCCAGTCGAGTCCTGCCCCAGCGAAACTAACGGACCCGTATTTACAGATTGAGGGAGG
CTACCGATTAAGTGGCGAGGTCACCATCAGCGGGGCCAAGAACTCTTCCTTGGCGCTGATGGCCGCCTCACTGCTGACCA
TGGAGCCCTGCCGGCTGCACAACGTGCCGAAGCTGGCGGACATCCGCATGATGAGCGCGATTCTCGAATCGCTGGGGGTG
CGCGTCAAGCCGGTCGCCGCCAATACCCTCGATATCGATCCGCGCTTTTTGAGCGTGCACCGCGCCCCCTACGAACTGGT
CAACAGCCTGCGCGCCAGCTTTTTTATTCTGGGGCCGATCCTGGCCCGGCTTGGGATGGCGCGCATTCCGCTGCCGGGCG
GTTGCGCCATCGGAGCGCGGCCGGTGGACTTGCACGTGCGGGGTCTGCAGGCGCTCGGCGCCCAGGTGCGCATCGAGCAT
GGCATCGTCGAAGCGCGCGCGCGCAAATTGCGCGGGGGGCGCATCTATCTCGATTACCCGAGCGTGGGAGCCACCGAAAC
GATCATGATGGCGGCCACCCTCGCCGAGGGCGAGACCGTGATCGAGAACGCCGCCCAGGAGCCCGAGGTGGTGGACCTCG
CCAACTTCTGCCGCTCGATGGGCGCCCACATCCGCGGGGCGGGCAGCAAAACCATCGTGATCAGCGGTGTGCCCCGCCTG
CACGGCAGCGAGTACCACGTCATTCCCGACCGCATCGAGACGGGCACGTTTATGGCCGCCGCCGCCATCACCCGTTCGAC
CCTGCGCATCGGGCCGGTCTTCCCCGAGCACCTCGCGGCGGTGCTTGCCAAGTTGCGGGAGATGGGTTCGGTGGTCAATC
TGGTCGGACCGGGCACACTGGAGGTGAGCCCCGGCCGGGTGATGGCCGCCACCGACATCGAGACGTTGCCGTTTCCGGGT
TTTCCCACCGACATGCAGGCGCAGTTTATGAGCGTGCTGGCGGTGAGCGAGGGCACCAGCATCATCTCGGAGACCGTCTT
TGAGAACCGCCTGATGCACGTCCCCGAACTCAATCGTTTGGGGGCCGACATCCGGGTGCGCTCGGGCCATGCCATCGTGC
GCGGGGTGCTCAAGCTGTCGGGAGCGCCGGTGGTGGCCACGGATTTGCGCGCCTCGGCGGCGCTGGTAATCGCGGGGCTC
GCCGCCCACGGCACGACGACGATTGCCGGACTGCACCACCTCGATCGCGGCTATGAGAGCATCGAACGGAAGTTGCAGGC
GCTGGGAGCGCGCATCGAAAGGCACCTCCCGAGCGCCCCGCCCAGCGAGGTCAGCAGTGCTGTGGCGGCCGGTCCGGACG
CCGCCGCTGCTCCTGTTTGA

Upstream 100 bases:

>100_bases
ACTTTGGCCGGGGCCTTACATCTCCACAGAATAGGGCAGATTTTCCAGCGATCTTTCCCTTACAATCTGGGGTATCCACA
CACCACCAATTACCGAACCC

Downstream 100 bases:

>100_bases
CTTTGCAGTGGAGGCGCAGCCGGCCACCGACAGCACAACCTCCCCTAAGCCACCCTCCTTAGAAATACTGCCGCCCTTTA
GGGCTGGCCCGGCGGATTCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MGIEPSLPQSSPAPAKLTDPYLQIEGGYRLSGEVTISGAKNSSLALMAASLLTMEPCRLHNVPKLADIRMMSAILESLGV
RVKPVAANTLDIDPRFLSVHRAPYELVNSLRASFFILGPILARLGMARIPLPGGCAIGARPVDLHVRGLQALGAQVRIEH
GIVEARARKLRGGRIYLDYPSVGATETIMMAATLAEGETVIENAAQEPEVVDLANFCRSMGAHIRGAGSKTIVISGVPRL
HGSEYHVIPDRIETGTFMAAAAITRSTLRIGPVFPEHLAAVLAKLREMGSVVNLVGPGTLEVSPGRVMAATDIETLPFPG
FPTDMQAQFMSVLAVSEGTSIISETVFENRLMHVPELNRLGADIRVRSGHAIVRGVLKLSGAPVVATDLRASAALVIAGL
AAHGTTTIAGLHHLDRGYESIERKLQALGARIERHLPSAPPSEVSSAVAAGPDAAAAPV

Sequences:

>Translated_459_residues
MGIEPSLPQSSPAPAKLTDPYLQIEGGYRLSGEVTISGAKNSSLALMAASLLTMEPCRLHNVPKLADIRMMSAILESLGV
RVKPVAANTLDIDPRFLSVHRAPYELVNSLRASFFILGPILARLGMARIPLPGGCAIGARPVDLHVRGLQALGAQVRIEH
GIVEARARKLRGGRIYLDYPSVGATETIMMAATLAEGETVIENAAQEPEVVDLANFCRSMGAHIRGAGSKTIVISGVPRL
HGSEYHVIPDRIETGTFMAAAAITRSTLRIGPVFPEHLAAVLAKLREMGSVVNLVGPGTLEVSPGRVMAATDIETLPFPG
FPTDMQAQFMSVLAVSEGTSIISETVFENRLMHVPELNRLGADIRVRSGHAIVRGVLKLSGAPVVATDLRASAALVIAGL
AAHGTTTIAGLHHLDRGYESIERKLQALGARIERHLPSAPPSEVSSAVAAGPDAAAAPV
>Mature_458_residues
GIEPSLPQSSPAPAKLTDPYLQIEGGYRLSGEVTISGAKNSSLALMAASLLTMEPCRLHNVPKLADIRMMSAILESLGVR
VKPVAANTLDIDPRFLSVHRAPYELVNSLRASFFILGPILARLGMARIPLPGGCAIGARPVDLHVRGLQALGAQVRIEHG
IVEARARKLRGGRIYLDYPSVGATETIMMAATLAEGETVIENAAQEPEVVDLANFCRSMGAHIRGAGSKTIVISGVPRLH
GSEYHVIPDRIETGTFMAAAAITRSTLRIGPVFPEHLAAVLAKLREMGSVVNLVGPGTLEVSPGRVMAATDIETLPFPGF
PTDMQAQFMSVLAVSEGTSIISETVFENRLMHVPELNRLGADIRVRSGHAIVRGVLKLSGAPVVATDLRASAALVIAGLA
AHGTTTIAGLHHLDRGYESIERKLQALGARIERHLPSAPPSEVSSAVAAGPDAAAAPV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=415, Percent_Identity=53.2530120481928, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_GLOVI (Q7NGP3)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926071.1
- ProteinModelPortal:   Q7NGP3
- SMR:   Q7NGP3
- GeneID:   2601526
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr3125
- NMPDR:   fig|251221.1.peg.3125
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   GVIO251221:GLR3125-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 48374; Mature: 48243

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: ACT_SITE 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEPSLPQSSPAPAKLTDPYLQIEGGYRLSGEVTISGAKNSSLALMAASLLTMEPCRLH
CCCCCCCCCCCCCCCCCCCCEEEEECCEEEECEEEEECCCCCCHHHHHHHHHHCCCHHHC
NVPKLADIRMMSAILESLGVRVKPVAANTLDIDPRFLSVHRAPYELVNSLRASFFILGPI
CCCCHHHHHHHHHHHHHCCCEEEEEECCEEECCCHHEEHHCCHHHHHHHHHHHHHHHHHH
LARLGMARIPLPGGCAIGARPVDLHVRGLQALGAQVRIEHGIVEARARKLRGGRIYLDYP
HHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEECC
SVGATETIMMAATLAEGETVIENAAQEPEVVDLANFCRSMGAHIRGAGSKTIVISGVPRL
CCCCCHHHHEEHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCC
HGSEYHVIPDRIETGTFMAAAAITRSTLRIGPVFPEHLAAVLAKLREMGSVVNLVGPGTL
CCCCEEECCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCEEEECCCCEE
EVSPGRVMAATDIETLPFPGFPTDMQAQFMSVLAVSEGTSIISETVFENRLMHVPELNRL
EECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHC
GADIRVRSGHAIVRGVLKLSGAPVVATDLRASAALVIAGLAAHGTTTIAGLHHLDRGYES
CCCEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERKLQALGARIERHLPSAPPSEVSSAVAAGPDAAAAPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GIEPSLPQSSPAPAKLTDPYLQIEGGYRLSGEVTISGAKNSSLALMAASLLTMEPCRLH
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECEEEEECCCCCCHHHHHHHHHHCCCHHHC
NVPKLADIRMMSAILESLGVRVKPVAANTLDIDPRFLSVHRAPYELVNSLRASFFILGPI
CCCCHHHHHHHHHHHHHCCCEEEEEECCEEECCCHHEEHHCCHHHHHHHHHHHHHHHHHH
LARLGMARIPLPGGCAIGARPVDLHVRGLQALGAQVRIEHGIVEARARKLRGGRIYLDYP
HHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEHHHHHHHHHHHCCCCEEEEECC
SVGATETIMMAATLAEGETVIENAAQEPEVVDLANFCRSMGAHIRGAGSKTIVISGVPRL
CCCCCHHHHEEHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCC
HGSEYHVIPDRIETGTFMAAAAITRSTLRIGPVFPEHLAAVLAKLREMGSVVNLVGPGTL
CCCCEEECCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCEEEECCCCEE
EVSPGRVMAATDIETLPFPGFPTDMQAQFMSVLAVSEGTSIISETVFENRLMHVPELNRL
EECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHC
GADIRVRSGHAIVRGVLKLSGAPVVATDLRASAALVIAGLAAHGTTTIAGLHHLDRGYES
CCCEEEECCHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
IERKLQALGARIERHLPSAPPSEVSSAVAAGPDAAAAPV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292