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The map label for this gene is gltA [H]

Identifier: 37522581

GI number: 37522581

Start: 3209602

End: 3210744

Strand: Direct

Name: gltA [H]

Synonym: glr3012

Alternate gene names: 37522581

Gene position: 3209602-3210744 (Clockwise)

Preceding gene: 37522580

Following gene: 37522582

Centisome position: 68.89

GC content: 61.33

Gene sequence:

>1143_bases
ATGAGCGGCGAGTATGTTCCTGGTCTGGAAGGCGTCCCTGCAACCCGTTCGAATATCAGTTTCGTGGACGGCAAAGCCGG
CGTCCTGGAGTACCGCGGCATCCCAATCGACCAGCTTGCCGAGTCGAGCACGTTTTTAGAGACCGCCTTTTTATTGATTT
TTGACCACCTGCCCACCAAGGACGAACTGCTCTCCTTCGAAGTCGAGATCCTGGGCCACCGGCGGGTCAAATACCGCATC
CGCGACATGATCAAAAGCTTCCCCGAGAGCGGCCGGCCGATGGTGGCCCTCCAGTCGTGCATCGCGGCGCTGGGGCTTTT
TTATCCGCTGCAAAACGAGAGCAAAGAAAAATACGCCTACGATTCGACTATCCGCCTACTCGCGAAGATGCCGACGATGG
TGGCGACGTTTCATCAGATGCGCCTGGGCAACGATCCCATCCCGCCGCGCGACGACTTGGGCCACGCCGCCAATTTTCTC
TACATGCTCACGGGCAAGGAACCCGACCCACGGGCGGCGCGCATCTTCGATGTCTGTCTGATGCTGCACGCCGAGCACAC
CGTCAACGCCTCGACTTTTTCGGCCCTGGTCACCGCCTCCACCCTGGCCGACCCCTATACCGTGATCACCTCGGCGGCGG
GCACCCTCTCAGGCCCGCTCCACGGCGGCGCCAACGAAGAGGTGATCCGCATGCTCAAGGAAATCGGCACCATCGAGCGC
GTCCGCCCCTACCTCGAGAATCGCCTCGCCCGCAAGGAAAAAATCATGGGCGTCGGCCACCGGGTCTACAAAGTCAAAGA
CCCGCGCGCCACGATCTTGCAGAATCTGGCCCAGGAGTTGTTCGACCGCTTCGGCCACAGCCGCCTCTACGACATCGCCG
TCGAAGTCGAGCGCGTTTGCGACGAGTTGCTCGGCCAAAAGGGCATCTACCCCAACGTCGACTTCTACTCGGGTCTGGTC
TACGAAAAGATGGGCATTCCCGCCGACATGTTCACCCCGGTATTCGCCATCTCGCGGGTGGCGGGGTGGCTCGCCCACTG
GCACGAGCAGTTGGCCGACAACCGCATCTTCCGTCCCACCCAGGTCTACACCGGCTCCCACAACGTCGAATTCACGCCTC
TGTCGCTGCGCTCCTACGCCTAG

Upstream 100 bases:

>100_bases
CTGGAGCGCATCCGCGATCGTATGGGGCTGCTGCCGCCTTTTTAAACCGGAAGCGCCGTTCGCGAATTTTACACACACGC
TTTGGAAAGGACGGGCAATT

Downstream 100 bases:

>100_bases
CGGTACAGTGGGGAGGAACACCACATCAAGGGGAAGGCCCTGATGGTGCGCCTGCCGCTCATCAACCTGCATCCGGATCA
TGTGGCCGAGGTGATCGAGA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSGEYVPGLEGVPATRSNISFVDGKAGVLEYRGIPIDQLAESSTFLETAFLLIFDHLPTKDELLSFEVEILGHRRVKYRI
RDMIKSFPESGRPMVALQSCIAALGLFYPLQNESKEKYAYDSTIRLLAKMPTMVATFHQMRLGNDPIPPRDDLGHAANFL
YMLTGKEPDPRAARIFDVCLMLHAEHTVNASTFSALVTASTLADPYTVITSAAGTLSGPLHGGANEEVIRMLKEIGTIER
VRPYLENRLARKEKIMGVGHRVYKVKDPRATILQNLAQELFDRFGHSRLYDIAVEVERVCDELLGQKGIYPNVDFYSGLV
YEKMGIPADMFTPVFAISRVAGWLAHWHEQLADNRIFRPTQVYTGSHNVEFTPLSLRSYA

Sequences:

>Translated_380_residues
MSGEYVPGLEGVPATRSNISFVDGKAGVLEYRGIPIDQLAESSTFLETAFLLIFDHLPTKDELLSFEVEILGHRRVKYRI
RDMIKSFPESGRPMVALQSCIAALGLFYPLQNESKEKYAYDSTIRLLAKMPTMVATFHQMRLGNDPIPPRDDLGHAANFL
YMLTGKEPDPRAARIFDVCLMLHAEHTVNASTFSALVTASTLADPYTVITSAAGTLSGPLHGGANEEVIRMLKEIGTIER
VRPYLENRLARKEKIMGVGHRVYKVKDPRATILQNLAQELFDRFGHSRLYDIAVEVERVCDELLGQKGIYPNVDFYSGLV
YEKMGIPADMFTPVFAISRVAGWLAHWHEQLADNRIFRPTQVYTGSHNVEFTPLSLRSYA
>Mature_379_residues
SGEYVPGLEGVPATRSNISFVDGKAGVLEYRGIPIDQLAESSTFLETAFLLIFDHLPTKDELLSFEVEILGHRRVKYRIR
DMIKSFPESGRPMVALQSCIAALGLFYPLQNESKEKYAYDSTIRLLAKMPTMVATFHQMRLGNDPIPPRDDLGHAANFLY
MLTGKEPDPRAARIFDVCLMLHAEHTVNASTFSALVTASTLADPYTVITSAAGTLSGPLHGGANEEVIRMLKEIGTIERV
RPYLENRLARKEKIMGVGHRVYKVKDPRATILQNLAQELFDRFGHSRLYDIAVEVERVCDELLGQKGIYPNVDFYSGLVY
EKMGIPADMFTPVFAISRVAGWLAHWHEQLADNRIFRPTQVYTGSHNVEFTPLSLRSYA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=328, Percent_Identity=26.8292682926829, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1786939, Length=379, Percent_Identity=36.6754617414248, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1786527, Length=370, Percent_Identity=34.8648648648649, Blast_Score=229, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17555174, Length=328, Percent_Identity=27.7439024390244, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319850, Length=374, Percent_Identity=24.0641711229947, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6324328, Length=367, Percent_Identity=24.2506811989101, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6325257, Length=347, Percent_Identity=25.9365994236311, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640126, Length=373, Percent_Identity=25.7372654155496, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24640124, Length=373, Percent_Identity=25.7372654155496, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21356863, Length=382, Percent_Identity=26.1780104712042, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42643; Mature: 42511

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEYVPGLEGVPATRSNISFVDGKAGVLEYRGIPIDQLAESSTFLETAFLLIFDHLPTK
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCH
DELLSFEVEILGHRRVKYRIRDMIKSFPESGRPMVALQSCIAALGLFYPLQNESKEKYAY
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
DSTIRLLAKMPTMVATFHQMRLGNDPIPPRDDLGHAANFLYMLTGKEPDPRAARIFDVCL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCEEEEEECCCCCCHHHHHHHHHH
MLHAEHTVNASTFSALVTASTLADPYTVITSAAGTLSGPLHGGANEEVIRMLKEIGTIER
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
VRPYLENRLARKEKIMGVGHRVYKVKDPRATILQNLAQELFDRFGHSRLYDIAVEVERVC
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DELLGQKGIYPNVDFYSGLVYEKMGIPADMFTPVFAISRVAGWLAHWHEQLADNRIFRPT
HHHHCCCCCCCCCHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QVYTGSHNVEFTPLSLRSYA
EEEECCCCCEEEECCCCCCC
>Mature Secondary Structure 
SGEYVPGLEGVPATRSNISFVDGKAGVLEYRGIPIDQLAESSTFLETAFLLIFDHLPTK
CCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCH
DELLSFEVEILGHRRVKYRIRDMIKSFPESGRPMVALQSCIAALGLFYPLQNESKEKYAY
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
DSTIRLLAKMPTMVATFHQMRLGNDPIPPRDDLGHAANFLYMLTGKEPDPRAARIFDVCL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCEEEEEECCCCCCHHHHHHHHHH
MLHAEHTVNASTFSALVTASTLADPYTVITSAAGTLSGPLHGGANEEVIRMLKEIGTIER
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
VRPYLENRLARKEKIMGVGHRVYKVKDPRATILQNLAQELFDRFGHSRLYDIAVEVERVC
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DELLGQKGIYPNVDFYSGLVYEKMGIPADMFTPVFAISRVAGWLAHWHEQLADNRIFRPT
HHHHCCCCCCCCCHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QVYTGSHNVEFTPLSLRSYA
EEEECCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]