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The map label for this gene is rsmH

Identifier: 37522496

GI number: 37522496

Start: 3124021

End: 3124965

Strand: Direct

Name: rsmH

Synonym: glr2927

Alternate gene names: 37522496

Gene position: 3124021-3124965 (Clockwise)

Preceding gene: 37522494

Following gene: 37522497

Centisome position: 67.05

GC content: 65.82

Gene sequence:

>945_bases
ATGCGACAAGACTTGACAGGAACTCCGCGATTTTTTAGGCTGACTCAAGGTTATCCAGGTCGCGCCCACTCCGCAGTGAA
CACTCTCCATCGATCGGTCCTGTTGGAAGAAACTATTGTCGGTCTGCAGGTGCACCCCGGCGGACTCTACCTTGACGCCA
CCGTCGGCCTGGGTGGGCACAGCGAGGCCATCTTGCGCACCGAAAGCACCCGGGTGGTCGCCCTCGATCAAGACGAGGAC
GCCCTTGCGCAGGCGCGGCTACGCCTGGCCCCCTTCGGCGAACGGGTGCGCTTTGAACACATCAACTTTGCCGAATTCGA
GCCGGGGGAGGAGCGCTTCGACGGCATCGTCGCCGATCTGGGCGTCAGTTCGATGCAACTGGATAGCCCCGAGCGGGGTT
TTTCGTGGCGGTTCGAATCGCCCCTCGACATGCGCATGGACGGCGGGGGCGAGGCCGAGACGGCGGCGGACCTGGTCAAC
ACCTGCAGCGCCGAGCAGTTGAGCGACCTGTTCTGGCGCTACGGTGAGGAGCGCTTCTCGCGGCGCATCGCCCGGCGGAT
CGTCGAGCGGCGCCCCTTGCGCACGACCACCGAACTGGCCGCGGTAGTCGCCTCGGCCATCCCGACCCGCCAGCCCATCC
ACCCCGCCACCCGCGTCTTTCAGGCGTTGCGCATCGCCGTCAACGGCGAAGTCGCAGCTCTGGAAACCTTTCTTGAGCGC
AGTCCCGACTGGCTGGTACCGGGAGGACGCCTCGCCGTCATCAGCTTCCACAGCCTTGAGGACCGGCCGGTCAAGCACCG
CTGGCGCGCCGATCCCCGTCTCGAAGTGCTCACCCGCAAAACGATCACAGCCGGCGAAGCTGAGATCCAGTCCAACCCCC
GCGCCCGTTCGGCCAGGCTGCGCCTGGCCCGCCGCCTTTCACCCAGTGAGGAGTCTCGATCGTGA

Upstream 100 bases:

>100_bases
TGCGGGGCGGCCTTCAAGCTTCAGTTTGAGATTTCCAAATGCTTGCCTCAATTGTCAAAAATTGCCGCGATCGGTTTCGA
ACACATCGACTCCCGAAAAT

Downstream 100 bases:

>100_bases
ACGCCCTACCCCAGAGCCAGGTTTCCCCAAATACCGGCGTCGTGCTGCCGCTCGAACGTCCCCTTGCCGCCCCGCCCACC
CCGGAGGAGTTAAAAACGCT

Product: hypothetical protein

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRQDLTGTPRFFRLTQGYPGRAHSAVNTLHRSVLLEETIVGLQVHPGGLYLDATVGLGGHSEAILRTESTRVVALDQDED
ALAQARLRLAPFGERVRFEHINFAEFEPGEERFDGIVADLGVSSMQLDSPERGFSWRFESPLDMRMDGGGEAETAADLVN
TCSAEQLSDLFWRYGEERFSRRIARRIVERRPLRTTTELAAVVASAIPTRQPIHPATRVFQALRIAVNGEVAALETFLER
SPDWLVPGGRLAVISFHSLEDRPVKHRWRADPRLEVLTRKTITAGEAEIQSNPRARSARLRLARRLSPSEESRS

Sequences:

>Translated_314_residues
MRQDLTGTPRFFRLTQGYPGRAHSAVNTLHRSVLLEETIVGLQVHPGGLYLDATVGLGGHSEAILRTESTRVVALDQDED
ALAQARLRLAPFGERVRFEHINFAEFEPGEERFDGIVADLGVSSMQLDSPERGFSWRFESPLDMRMDGGGEAETAADLVN
TCSAEQLSDLFWRYGEERFSRRIARRIVERRPLRTTTELAAVVASAIPTRQPIHPATRVFQALRIAVNGEVAALETFLER
SPDWLVPGGRLAVISFHSLEDRPVKHRWRADPRLEVLTRKTITAGEAEIQSNPRARSARLRLARRLSPSEESRS
>Mature_314_residues
MRQDLTGTPRFFRLTQGYPGRAHSAVNTLHRSVLLEETIVGLQVHPGGLYLDATVGLGGHSEAILRTESTRVVALDQDED
ALAQARLRLAPFGERVRFEHINFAEFEPGEERFDGIVADLGVSSMQLDSPERGFSWRFESPLDMRMDGGGEAETAADLVN
TCSAEQLSDLFWRYGEERFSRRIARRIVERRPLRTTTELAAVVASAIPTRQPIHPATRVFQALRIAVNGEVAALETFLER
SPDWLVPGGRLAVISFHSLEDRPVKHRWRADPRLEVLTRKTITAGEAEIQSNPRARSARLRLARRLSPSEESRS

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=347, Percent_Identity=38.328530259366, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI165377202, Length=208, Percent_Identity=40.3846153846154, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1786270, Length=313, Percent_Identity=43.4504792332268, Blast_Score=204, Evalue=7e-54,
Organism=Drosophila melanogaster, GI62472493, Length=326, Percent_Identity=34.6625766871166, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI28571637, Length=326, Percent_Identity=34.6625766871166, Blast_Score=144, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_GLOVI (Q7NCQ1)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925873.1
- ProteinModelPortal:   Q7NCQ1
- SMR:   Q7NCQ1
- GeneID:   2601328
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr2927
- NMPDR:   fig|251221.1.peg.2927
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- BioCyc:   GVIO251221:GLR2927-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 35212; Mature: 35212

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: BINDING 76-76 BINDING 103-103 BINDING 119-119 BINDING 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDLTGTPRFFRLTQGYPGRAHSAVNTLHRSVLLEETIVGLQVHPGGLYLDATVGLGGH
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCC
SEAILRTESTRVVALDQDEDALAQARLRLAPFGERVRFEHINFAEFEPGEERFDGIVADL
CCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHC
GVSSMQLDSPERGFSWRFESPLDMRMDGGGEAETAADLVNTCSAEQLSDLFWRYGEERFS
CCCCEECCCCCCCCCEECCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RRIARRIVERRPLRTTTELAAVVASAIPTRQPIHPATRVFQALRIAVNGEVAALETFLER
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
SPDWLVPGGRLAVISFHSLEDRPVKHRWRADPRLEVLTRKTITAGEAEIQSNPRARSARL
CCCEECCCCEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHH
RLARRLSPSEESRS
HHHHHCCCCCCCCC
>Mature Secondary Structure
MRQDLTGTPRFFRLTQGYPGRAHSAVNTLHRSVLLEETIVGLQVHPGGLYLDATVGLGGH
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCC
SEAILRTESTRVVALDQDEDALAQARLRLAPFGERVRFEHINFAEFEPGEERFDGIVADL
CCEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHC
GVSSMQLDSPERGFSWRFESPLDMRMDGGGEAETAADLVNTCSAEQLSDLFWRYGEERFS
CCCCEECCCCCCCCCEECCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RRIARRIVERRPLRTTTELAAVVASAIPTRQPIHPATRVFQALRIAVNGEVAALETFLER
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHC
SPDWLVPGGRLAVISFHSLEDRPVKHRWRADPRLEVLTRKTITAGEAEIQSNPRARSARL
CCCEECCCCEEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHHH
RLARRLSPSEESRS
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292