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The map label for this gene is pleC [H]

Identifier: 37522318

GI number: 37522318

Start: 2921186

End: 2925076

Strand: Direct

Name: pleC [H]

Synonym: glr2749

Alternate gene names: 37522318

Gene position: 2921186-2925076 (Clockwise)

Preceding gene: 37522317

Following gene: 37522319

Centisome position: 62.7

GC content: 65.51

Gene sequence:

>3891_bases
ATGTCCATGGTAAGACGCGGGACCCGCAGCGATTCGAGTTCAATATCGTCTGCCAGCCAAGACAAGCAACAGGACCGGCA
CCACCCCGCGCACGGGTGCCTGTCCGGCGGTGGAGAGATGGGCGCGCTGATGCGGGCGAAGGACTGGTCGGCCTCGCCCC
TCGAAGCGCCCGATCACTGGCCGCAGAGCCTCAAGACAGCCCTGCGCATCTTGCTCACGTCGCGCTACGCGATGTGGATG
GGCTGGGGGGAGCCGCTCACTTTCTTCTACAACGATGCCTACCGCCCGACGTTGGGCATCAAGCATCCCTGGGCGCTCGG
CCACCCCGCACAGCAAGTCTGGAAGGAAATCTGGCGCGATATCGCTCCGCGCATCGAAACCGTACTCAAGACGGGCGAAG
CCACTTACGACGAGGCGCTGTTGTTGTTTTTGGAGCGCAGCGGCTTTCCGGAGGAGACCTATCACACGTTTTCCTATAGC
CCGCTGGCCGACGAAGCCGGTGAGGTCGCCGGCATGCTGTGCGTGGTCACCGAGGAGACCGAGCGCGTCATCGGCGAGCG
CCGCATGGCGCTTTTGCGCGAGTTGGCCTCGGATCTGGCCGCGACGCAGACCCAGGAGGAAGTGTTCGCCGCCGTCCAGA
GGCAGGTGGGCAAGTATTCAAAAGATCTGCCCTTTACGCTGATGTACCTGTTCGACAGCGACGCGGGCGGCCGGGCGCGG
CTTGCGGCGGCCACGGGCATAGAAGCCAAACATCCGGGGGCGCGGCCGATCATCGACCCTGCAACCTACGGCGGACCCTG
GTCGGCCCATAAGCTTTGGGAGGGAGCGCCGCCCATTTTACTGAACGATTTCGAGGGGCAATTGGGCGGGAATCCGCCGA
GCGGAGGGTGGGACAAGCCGCCGCACCAGGTGAGCGTCGTCCCGATCAAAAGCCAGGGCCAGGAGCGGCCGGCCGGCTTT
CTGGTCGCGGCACTCAATCCGTACCGCCGTTATGACGCCGAGTACGCAGGCTTTGTCGATCTTTTGACCGGTCAGATTGC
CGCGGGTCTGGCCAATGCCCGGGCTTACGAGGCGGAGTGCCGCAGGGCCGAGGCGCTCGCCGAGATCGACCGCGCCAAGA
CCGTTTTTTTCTCCAACGTCAGCCACGAGTTCCGCACGCCGCTATCGCTGCTGCTTGGACCGCTGGAAGATGTGCTGGCC
GGCGACGGTATTTCGGCACCGACGCGCGAACAATTGACCCTGGCCCAGCGCAACGGCAGGAGGCTCCTGAAGCTGGTCAA
TACGCTGTTGGATTTCAGCCGCATCGAGGCCGGCCGGATCCAGGCGAATTTTCTGCCCACCGACCTGGCCTCCCTCACGG
CGCAACTGGTCTCGGTCTTCCGCTCGGCCGTCGAAAAGGCCGGTCTGCGCCTGGTGATCGACTGCCCGCCGCTCGCAGAA
GCGGTCTATGTCGATCGCGACATGTGGGAGAAAATCGTCCTCAACCTGCTCTCGAACGCCTTCAAGTTCACCCTCCGGGG
GCAAATCGCCGTCCGGCTGCGCCAGCAAACCGGTGAAGTGTGCCTGGAGCTCGAAGACACCGGGGTCGGCATTGCCGCCC
ACGAGTTGCCGCGCATCTTCGATCGCTTTCATCGGGTGGCGGGGGTGGCGGGGCGCTCCCACGAAGGTTCCGGCATCGGT
TTGGCCCTGGTGGCCGAACTGGTCGAGATCCACGGCGGCAAGGTTTCGGTGCAAAGCGTTTCGGGCCGGGGCAGCACCTT
CACCGTGCGGTTGCCCACCGGAACGGCCCACCTGCCTGCCGATCGCATTGGGGTGGCCCCAGGGCTCGCTTCCACCGCCG
TCGCTGCCGACATCTTCGCCGATGAGGCAGCGCAGTGGACCAGCGGATGGCACGAAGAATGGCTCCCGCCACCTCCGAAT
CTTGCCCCGGACGCAGAGCAGCGAGCCCCCGACACTCCCCGTCCGTGCGTCCTGGTGGTCGATGACAACGCCGACATGCG
GGCGTACATCGCGAACTTGCTTAAAGCTCACTACGAGGTCGTTCTGGCCGGCGACGGCGTCGAGGCGCTGGCCGCTGTCG
AGCGCCGGATGCCGGATCTGGTGCTCACCGATGTGATGATGCCCCGGCTCGACGGCTTCGGTCTGCTGGCCGCTTTGCGG
ACGGACGAGCGCACCCGCGCACTGCCGGTGATTGTCCTGTCGGCACGGGCCGGGGAGGAGGCCACGCTCGCGGGCCTGGA
AAGGGGAGCGGACGATTATCTGAGCAAACCGTTTGCCGCTCGGGAATTGTTGGGGCGGGTGAAGGCCAATCTGGAACTTT
CGCGATTGCGCGGAGAGACTGCCCGCCTGTTGCACGCCTCCGAGGAGCGCGCCCGCTTGGCCATCCGGGTAGGAAGGCTC
GGGACCTGGCGCTTCGTTCCGACAAGCGGCGTGGCCACCATGGACGAGCGGATGCGCGAAATCTGGGGCGAGCCGGAGGA
TACTTTCCAACTATCCCTGGCGCAGGCGATGGAGCGCATCCACCCGGCCGACCGGGAGCGCGTGTCCCAGGCGGTCGACG
CGGCGCTCGATCCGGCCTCGGCGGGCACCCTCGAAATCGACTACCGCATCGTCTGGCCCAACGGAAGCGAGCGCTGGGTC
TCAGCCAACGGGCAGGTGTTCTTTGAGCAGACAGAAGCGGGGAGCAGGCGGGCGGTCGATTTTATCGGCACCGCCCTGGA
TATCACCGAACGCAAGCGCATCGAGCAGGCGCTCGCCGGGAGCGAACAGCGCTACCGCCTGCTGGCCGAGTCGATCCCGC
AGCTGGTGTGGACGGCCGATGTCGGCGGGACGCTTTTGGATGTCAACGGGCGGTGGTCCCAGTACACCGGGTTCACCCTC
GAACAGGTCAAAAAGTCCGGTTGGGAGTCGGTGGTGCATCCGGAGGACGTGCCGGGTTTGCGGCGGCAATGGACAGCGGC
GATCAAAGCCGTCGCCGCCTATCGGGCCGAGGGACGCATGCGGCGCACGGACGGAACTTACCGCTGGCACCTCCACCAGG
CCATGCCGTTAATGGACGGGGAGGGCCGCATTCTCAAGTGGTTCGGCACGGCGACCGACATCGAGGAGCGCAAGCAGCTG
GAGGCTGAGCGCGAACAACTGCTCGAGCGCGCCGAGCAGGCCCGGGAGGCGGCCGAAGCCGCCAACCGCACCAAAGACGA
ATTTTTGGCCATCCTCGGGCACGAGTTGCGCACGCCGCTCAATCCGATCATCGGCTGGACCCAGATGCTCCGGCGCGGGA
AGGTCGGCCCGGACAAACACGATCAGGCCCTGGAGATCATCGAGCGCAATGCCCGGCTGCAGACGCAACTGATCGACGAC
CTGCTCGATGTTTCGCGGATCATGCGCGGTTCCTTGCGCATTGCCCCCCAGCCCATAACGCTGGCCGCCATCGTTGTTTG
CGCCCTCGAAGCGGTGCGTGGACTGGCAGAACAAAAACAAGTGCAGCTATTCGAACAGCTGCGGACGACAGCCCCGCTCA
GCGCCGATCCGACCCGCCTGCAGCAGGTGGTGTGGAACCTACTCACCAATGCCGTCAAGTTCACCCCGGCCGGAGGACAG
GTTCAGGTACGGCTGGAGTCGGGCGGGGGGATGGCCCGGCTCACCATCAGCGATACCGGCGTGGGCATCCCCGCCGAATT
TTTGCCGCACCTGTTCGAGCGTTTCCGGCAGGCGGATACCAAGAGCACGCGCGAACAAAAAGGTTTGGGGTTGGGCCTGT
TCATCGTACGCCACATCGTCGAAGCCCACGGCGGCACGGTGCAGGCCGAGAGCGAAGGCGAAGGCAAAGGAGCCGCTTTC
ACCGTCGTGCTGCCCCTTGGGGGCGAGGCCCAGCGGCAAGCCAAGCCGTGA

Upstream 100 bases:

>100_bases
GGGGCGTCCTCCTCCAGTCCTATGTCCTCGGGTAGAAAAACCGCCAGGCGGCCTATTCACACCGGCTCGTCGGATATCCT
GTCTATAGACAAAATCCGGC

Downstream 100 bases:

>100_bases
GCGGCACCGGTGGAAAGCGAAAGACATGGCTTTTCTCACCATCGGCTTCCCTTGGCCGGATACTGCCTCTGTGGGTAATC
CAGGGACGTATGGCTGCACG

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1296; Mature: 1295

Protein sequence:

>1296_residues
MSMVRRGTRSDSSSISSASQDKQQDRHHPAHGCLSGGGEMGALMRAKDWSASPLEAPDHWPQSLKTALRILLTSRYAMWM
GWGEPLTFFYNDAYRPTLGIKHPWALGHPAQQVWKEIWRDIAPRIETVLKTGEATYDEALLLFLERSGFPEETYHTFSYS
PLADEAGEVAGMLCVVTEETERVIGERRMALLRELASDLAATQTQEEVFAAVQRQVGKYSKDLPFTLMYLFDSDAGGRAR
LAAATGIEAKHPGARPIIDPATYGGPWSAHKLWEGAPPILLNDFEGQLGGNPPSGGWDKPPHQVSVVPIKSQGQERPAGF
LVAALNPYRRYDAEYAGFVDLLTGQIAAGLANARAYEAECRRAEALAEIDRAKTVFFSNVSHEFRTPLSLLLGPLEDVLA
GDGISAPTREQLTLAQRNGRRLLKLVNTLLDFSRIEAGRIQANFLPTDLASLTAQLVSVFRSAVEKAGLRLVIDCPPLAE
AVYVDRDMWEKIVLNLLSNAFKFTLRGQIAVRLRQQTGEVCLELEDTGVGIAAHELPRIFDRFHRVAGVAGRSHEGSGIG
LALVAELVEIHGGKVSVQSVSGRGSTFTVRLPTGTAHLPADRIGVAPGLASTAVAADIFADEAAQWTSGWHEEWLPPPPN
LAPDAEQRAPDTPRPCVLVVDDNADMRAYIANLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALR
TDERTRALPVIVLSARAGEEATLAGLERGADDYLSKPFAARELLGRVKANLELSRLRGETARLLHASEERARLAIRVGRL
GTWRFVPTSGVATMDERMREIWGEPEDTFQLSLAQAMERIHPADRERVSQAVDAALDPASAGTLEIDYRIVWPNGSERWV
SANGQVFFEQTEAGSRRAVDFIGTALDITERKRIEQALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTL
EQVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAYRAEGRMRRTDGTYRWHLHQAMPLMDGEGRILKWFGTATDIEERKQL
EAEREQLLERAEQAREAAEAANRTKDEFLAILGHELRTPLNPIIGWTQMLRRGKVGPDKHDQALEIIERNARLQTQLIDD
LLDVSRIMRGSLRIAPQPITLAAIVVCALEAVRGLAEQKQVQLFEQLRTTAPLSADPTRLQQVVWNLLTNAVKFTPAGGQ
VQVRLESGGGMARLTISDTGVGIPAEFLPHLFERFRQADTKSTREQKGLGLGLFIVRHIVEAHGGTVQAESEGEGKGAAF
TVVLPLGGEAQRQAKP

Sequences:

>Translated_1296_residues
MSMVRRGTRSDSSSISSASQDKQQDRHHPAHGCLSGGGEMGALMRAKDWSASPLEAPDHWPQSLKTALRILLTSRYAMWM
GWGEPLTFFYNDAYRPTLGIKHPWALGHPAQQVWKEIWRDIAPRIETVLKTGEATYDEALLLFLERSGFPEETYHTFSYS
PLADEAGEVAGMLCVVTEETERVIGERRMALLRELASDLAATQTQEEVFAAVQRQVGKYSKDLPFTLMYLFDSDAGGRAR
LAAATGIEAKHPGARPIIDPATYGGPWSAHKLWEGAPPILLNDFEGQLGGNPPSGGWDKPPHQVSVVPIKSQGQERPAGF
LVAALNPYRRYDAEYAGFVDLLTGQIAAGLANARAYEAECRRAEALAEIDRAKTVFFSNVSHEFRTPLSLLLGPLEDVLA
GDGISAPTREQLTLAQRNGRRLLKLVNTLLDFSRIEAGRIQANFLPTDLASLTAQLVSVFRSAVEKAGLRLVIDCPPLAE
AVYVDRDMWEKIVLNLLSNAFKFTLRGQIAVRLRQQTGEVCLELEDTGVGIAAHELPRIFDRFHRVAGVAGRSHEGSGIG
LALVAELVEIHGGKVSVQSVSGRGSTFTVRLPTGTAHLPADRIGVAPGLASTAVAADIFADEAAQWTSGWHEEWLPPPPN
LAPDAEQRAPDTPRPCVLVVDDNADMRAYIANLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALR
TDERTRALPVIVLSARAGEEATLAGLERGADDYLSKPFAARELLGRVKANLELSRLRGETARLLHASEERARLAIRVGRL
GTWRFVPTSGVATMDERMREIWGEPEDTFQLSLAQAMERIHPADRERVSQAVDAALDPASAGTLEIDYRIVWPNGSERWV
SANGQVFFEQTEAGSRRAVDFIGTALDITERKRIEQALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTL
EQVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAYRAEGRMRRTDGTYRWHLHQAMPLMDGEGRILKWFGTATDIEERKQL
EAEREQLLERAEQAREAAEAANRTKDEFLAILGHELRTPLNPIIGWTQMLRRGKVGPDKHDQALEIIERNARLQTQLIDD
LLDVSRIMRGSLRIAPQPITLAAIVVCALEAVRGLAEQKQVQLFEQLRTTAPLSADPTRLQQVVWNLLTNAVKFTPAGGQ
VQVRLESGGGMARLTISDTGVGIPAEFLPHLFERFRQADTKSTREQKGLGLGLFIVRHIVEAHGGTVQAESEGEGKGAAF
TVVLPLGGEAQRQAKP
>Mature_1295_residues
SMVRRGTRSDSSSISSASQDKQQDRHHPAHGCLSGGGEMGALMRAKDWSASPLEAPDHWPQSLKTALRILLTSRYAMWMG
WGEPLTFFYNDAYRPTLGIKHPWALGHPAQQVWKEIWRDIAPRIETVLKTGEATYDEALLLFLERSGFPEETYHTFSYSP
LADEAGEVAGMLCVVTEETERVIGERRMALLRELASDLAATQTQEEVFAAVQRQVGKYSKDLPFTLMYLFDSDAGGRARL
AAATGIEAKHPGARPIIDPATYGGPWSAHKLWEGAPPILLNDFEGQLGGNPPSGGWDKPPHQVSVVPIKSQGQERPAGFL
VAALNPYRRYDAEYAGFVDLLTGQIAAGLANARAYEAECRRAEALAEIDRAKTVFFSNVSHEFRTPLSLLLGPLEDVLAG
DGISAPTREQLTLAQRNGRRLLKLVNTLLDFSRIEAGRIQANFLPTDLASLTAQLVSVFRSAVEKAGLRLVIDCPPLAEA
VYVDRDMWEKIVLNLLSNAFKFTLRGQIAVRLRQQTGEVCLELEDTGVGIAAHELPRIFDRFHRVAGVAGRSHEGSGIGL
ALVAELVEIHGGKVSVQSVSGRGSTFTVRLPTGTAHLPADRIGVAPGLASTAVAADIFADEAAQWTSGWHEEWLPPPPNL
APDAEQRAPDTPRPCVLVVDDNADMRAYIANLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALRT
DERTRALPVIVLSARAGEEATLAGLERGADDYLSKPFAARELLGRVKANLELSRLRGETARLLHASEERARLAIRVGRLG
TWRFVPTSGVATMDERMREIWGEPEDTFQLSLAQAMERIHPADRERVSQAVDAALDPASAGTLEIDYRIVWPNGSERWVS
ANGQVFFEQTEAGSRRAVDFIGTALDITERKRIEQALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTLE
QVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAYRAEGRMRRTDGTYRWHLHQAMPLMDGEGRILKWFGTATDIEERKQLE
AEREQLLERAEQAREAAEAANRTKDEFLAILGHELRTPLNPIIGWTQMLRRGKVGPDKHDQALEIIERNARLQTQLIDDL
LDVSRIMRGSLRIAPQPITLAAIVVCALEAVRGLAEQKQVQLFEQLRTTAPLSADPTRLQQVVWNLLTNAVKFTPAGGQV
QVRLESGGGMARLTISDTGVGIPAEFLPHLFERFRQADTKSTREQKGLGLGLFIVRHIVEAHGGTVQAESEGEGKGAAFT
VVLPLGGEAQRQAKP

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=398, Percent_Identity=29.6482412060301, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI48994928, Length=416, Percent_Identity=30.2884615384615, Blast_Score=146, Evalue=9e-36,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=35.15625, Blast_Score=140, Evalue=5e-34,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=34.5238095238095, Blast_Score=133, Evalue=9e-32,
Organism=Escherichia coli, GI87081816, Length=463, Percent_Identity=29.3736501079914, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=32.618025751073, Blast_Score=107, Evalue=6e-24,
Organism=Escherichia coli, GI1786912, Length=292, Percent_Identity=32.1917808219178, Blast_Score=106, Evalue=9e-24,
Organism=Escherichia coli, GI1786783, Length=260, Percent_Identity=28.8461538461538, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=29.8642533936652, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=29.6747967479675, Blast_Score=103, Evalue=8e-23,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=29.718875502008, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=31.6666666666667, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=39.4736842105263, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=30.4932735426009, Blast_Score=84, Evalue=7e-17,
Organism=Escherichia coli, GI1788394, Length=156, Percent_Identity=34.6153846153846, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=37.0689655172414, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI2367329, Length=119, Percent_Identity=42.0168067226891, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=108, Percent_Identity=40.7407407407407, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=182, Percent_Identity=31.8681318681319, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788550, Length=181, Percent_Identity=31.4917127071823, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1787375, Length=114, Percent_Identity=35.0877192982456, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=174, Percent_Identity=32.183908045977, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790860, Length=122, Percent_Identity=36.0655737704918, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788192, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1790552, Length=104, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 142527; Mature: 142396

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMVRRGTRSDSSSISSASQDKQQDRHHPAHGCLSGGGEMGALMRAKDWSASPLEAPDHW
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHEECCCCCCCCCCCCCCC
PQSLKTALRILLTSRYAMWMGWGEPLTFFYNDAYRPTLGIKHPWALGHPAQQVWKEIWRD
HHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IAPRIETVLKTGEATYDEALLLFLERSGFPEETYHTFSYSPLADEAGEVAGMLCVVTEET
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCEECCCCCHHHHHHHHEEEEEEECHH
ERVIGERRMALLRELASDLAATQTQEEVFAAVQRQVGKYSKDLPFTLMYLFDSDAGGRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEE
LAAATGIEAKHPGARPIIDPATYGGPWSAHKLWEGAPPILLNDFEGQLGGNPPSGGWDKP
EEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCC
PHQVSVVPIKSQGQERPAGFLVAALNPYRRYDAEYAGFVDLLTGQIAAGLANARAYEAEC
CCCEEEEEECCCCCCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAEALAEIDRAKTVFFSNVSHEFRTPLSLLLGPLEDVLAGDGISAPTREQLTLAQRNGR
HHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCH
RLLKLVNTLLDFSRIEAGRIQANFLPTDLASLTAQLVSVFRSAVEKAGLRLVIDCPPLAE
HHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHH
AVYVDRDMWEKIVLNLLSNAFKFTLRGQIAVRLRQQTGEVCLELEDTGVGIAAHELPRIF
HHHHCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
DRFHRVAGVAGRSHEGSGIGLALVAELVEIHGGKVSVQSVSGRGSTFTVRLPTGTAHLPA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCH
DRIGVAPGLASTAVAADIFADEAAQWTSGWHEEWLPPPPNLAPDAEQRAPDTPRPCVLVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEE
DDNADMRAYIANLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALR
ECCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHH
TDERTRALPVIVLSARAGEEATLAGLERGADDYLSKPFAARELLGRVKANLELSRLRGET
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHCCHH
ARLLHASEERARLAIRVGRLGTWRFVPTSGVATMDERMREIWGEPEDTFQLSLAQAMERI
HHHHHCCHHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
HPADRERVSQAVDAALDPASAGTLEIDYRIVWPNGSERWVSANGQVFFEQTEAGSRRAVD
CCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEECCCEEEEEECCCCCCHHHH
FIGTALDITERKRIEQALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCHH
EQVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAYRAEGRMRRTDGTYRWHLHQAMPLMDG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCC
EGRILKWFGTATDIEERKQLEAEREQLLERAEQAREAAEAANRTKDEFLAILGHELRTPL
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
NPIIGWTQMLRRGKVGPDKHDQALEIIERNARLQTQLIDDLLDVSRIMRGSLRIAPQPIT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCHH
LAAIVVCALEAVRGLAEQKQVQLFEQLRTTAPLSADPTRLQQVVWNLLTNAVKFTPAGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCE
VQVRLESGGGMARLTISDTGVGIPAEFLPHLFERFRQADTKSTREQKGLGLGLFIVRHIV
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
EAHGGTVQAESEGEGKGAAFTVVLPLGGEAQRQAKP
HHCCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SMVRRGTRSDSSSISSASQDKQQDRHHPAHGCLSGGGEMGALMRAKDWSASPLEAPDHW
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHEECCCCCCCCCCCCCCC
PQSLKTALRILLTSRYAMWMGWGEPLTFFYNDAYRPTLGIKHPWALGHPAQQVWKEIWRD
HHHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IAPRIETVLKTGEATYDEALLLFLERSGFPEETYHTFSYSPLADEAGEVAGMLCVVTEET
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHCCEECCCCCHHHHHHHHEEEEEEECHH
ERVIGERRMALLRELASDLAATQTQEEVFAAVQRQVGKYSKDLPFTLMYLFDSDAGGRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEE
LAAATGIEAKHPGARPIIDPATYGGPWSAHKLWEGAPPILLNDFEGQLGGNPPSGGWDKP
EEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCC
PHQVSVVPIKSQGQERPAGFLVAALNPYRRYDAEYAGFVDLLTGQIAAGLANARAYEAEC
CCCEEEEEECCCCCCCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAEALAEIDRAKTVFFSNVSHEFRTPLSLLLGPLEDVLAGDGISAPTREQLTLAQRNGR
HHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCH
RLLKLVNTLLDFSRIEAGRIQANFLPTDLASLTAQLVSVFRSAVEKAGLRLVIDCPPLAE
HHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHH
AVYVDRDMWEKIVLNLLSNAFKFTLRGQIAVRLRQQTGEVCLELEDTGVGIAAHELPRIF
HHHHCHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
DRFHRVAGVAGRSHEGSGIGLALVAELVEIHGGKVSVQSVSGRGSTFTVRLPTGTAHLPA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCH
DRIGVAPGLASTAVAADIFADEAAQWTSGWHEEWLPPPPNLAPDAEQRAPDTPRPCVLVV
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEE
DDNADMRAYIANLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALR
ECCCCHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHH
TDERTRALPVIVLSARAGEEATLAGLERGADDYLSKPFAARELLGRVKANLELSRLRGET
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCCCHHHHHCCHH
ARLLHASEERARLAIRVGRLGTWRFVPTSGVATMDERMREIWGEPEDTFQLSLAQAMERI
HHHHHCCHHHHEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
HPADRERVSQAVDAALDPASAGTLEIDYRIVWPNGSERWVSANGQVFFEQTEAGSRRAVD
CCCCHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEECCCEEEEEECCCCCCHHHH
FIGTALDITERKRIEQALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCCCCHH
EQVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAYRAEGRMRRTDGTYRWHLHQAMPLMDG
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCC
EGRILKWFGTATDIEERKQLEAEREQLLERAEQAREAAEAANRTKDEFLAILGHELRTPL
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
NPIIGWTQMLRRGKVGPDKHDQALEIIERNARLQTQLIDDLLDVSRIMRGSLRIAPQPIT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCHH
LAAIVVCALEAVRGLAEQKQVQLFEQLRTTAPLSADPTRLQQVVWNLLTNAVKFTPAGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCE
VQVRLESGGGMARLTISDTGVGIPAEFLPHLFERFRQADTKSTREQKGLGLGLFIVRHIV
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
EAHGGTVQAESEGEGKGAAFTVVLPLGGEAQRQAKP
HHCCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]