| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is spoT [H]
Identifier: 37522317
GI number: 37522317
Start: 2918792
End: 2921068
Strand: Direct
Name: spoT [H]
Synonym: glr2748
Alternate gene names: 37522317
Gene position: 2918792-2921068 (Clockwise)
Preceding gene: 37522316
Following gene: 37522318
Centisome position: 62.65
GC content: 59.9
Gene sequence:
>2277_bases GTGAGAAAAGGGGTGGTGGGCGGTATGCATCTGGTCTCAGCCGAGTTCGAAACGCTCCAGCTTCCTGACTGGCTCAAAGA TTGCCTGGATCATCCGCACGGCACCCAGGAGTGGACCACCGCCAACAGCGAGACGAGCCTGACCACACCGCGCACCGTGA GCCTCGATCGCGGCCTGATCGCCCGCGCCTTCGACTTTGCCTATCGCCTGCACACCGGTCAAAACCGCGCCTCGGGCGAA CCTTATATCCTCCACCCGGTGCAGGTGGCGGGGATGCTGCGCGAATTGGGTTCCGACAGCGCGATGGTGGCGGCGGGTTT TTTGCACGACATCATCGAGGATACCGCCACCACCTCCGAAGACCTCGAACAGCTTTTCGGCGAACAGGTGCGGCTCCTGG TCGAAGGAGTGACCAAGCTCTCAAAATTTACCTTCGACAGCAAAGAAGAGCGCCAGGCCGAGAATTTCCGGCGCATGTTT TTGGCGATGGCCCAGGATATCCGCGTCATCGTCGTCAAGCTCGCCGACCGCCTGCACAACATGCGGACGCTCGATTTTCT GCCCACCCACAAGCAGCGTCGCATCGCCCAGGAGACGATGGACATCTTCGCGCCCCTGGCTAACCGCCTGGGTATCTGGC GCTTTAAGTGGGAACTCGAAGACCTCGCGTTCAAGTACCTCGATCCCGACGCCTATCGCCACATGCAGAAGCTCGTCTCC CAGAAGCGGGCCGAGCGCGAGCAATTTATCGATCAAGTCGTGCAGACCATCCGTGCCGAGATCGACCGCCAGCACATTCA TGGCGAGATCACCGGTCGGCCGAAGCATCTGTGGGGCATTTACCAGAAGATGCAGCGCCAACAAAAAGAATTTCACGAAA TTTATGATGTCTCGGCGGTGCGGATCATCGTCGAGCAGCAAGAGGAATGTTACCGGGCGCTGTCGATCGTCCATAACAAA TTCCGCCCGATCCCCGGTCGCTTCAAAGATTACATCGGCCTGCCCAAACCAAACCGCTACCAGTCGCTGCACACGGCGGT GGTCGGCCCCGAGGGCAAGCCCCTCGAAGTGCAGATCCGCACGGTGGACATGCACCGCATCGCTGAGTACGGTATTGCCG CCCACTGGAAATACAAGGAGGCTGGCTCGGTAGTGGTAGCGAGCCAGGAAGAAAAATTTACCTGGCTCAGGCAACTGCTC GACTGGCAGAGCGATCTCAAAGACGCGGGCGAATACCTGGAGACGATCAAAGAAGATCTCTTCTATTCAGAAGTCTACGT CTTCACCCCAAAAGGCGATGTGGTCGAACTGCCGCGCGGCGGTACCCCCGTCGATTTTGCCTACCGTATCCACACCGAGG TGGGCAACCGCTGCGTGGGTGCTAAAGTCAACGACCGGATGGTGCCGCTCGATTCGCAACTCAAAAATGGCGACATCGTC GAGATTCTCACGTCCAAAAATTCCCACCCGAGCCTCGACTGGATCAATTTCGTCGTTACTTCTTCGGCCAAAAACCGCAT CCGCCAGTGGTTCAAGCGCTCCACCCGCGAGCAGAACATCGAGCAGGGCCGCGACATGCTCGCCCGCGAACTGGGCAAGG GCAATCTCGAGAACCTGCTCAAATCCGACCGCATGCTCAAAGTCGCCCAAAGACTCAATTTCACCACCGTCGAGGATTTG CTCGCCGCCCTCGGGTACGGCGAGGTGACGCAGGCCAGCGTGCTCAACAAGCTCCAGGAGAGCACCCCGACCTCCACCCC GGCCGAAATGGTCGAACTGCCCACCCAGAAGAGCGCCGGGATGCCCACCCCGAGCGACAAACCGATCCTGGGCATCGAGG GGATACCCTACCATTTGGCCAAGTGTTGCAACCCGCTGCCCGGTGAACCGATCATCGGCGTCGTCACCCGCATCAACCGC AGCATCAGCATCCACCACCACGGTTGCCCGAACGCCACCAAAGTCGACCCCGACCAGTTGATTCCCGTTTCCTGGAACCG CAGCTATACCCAGCCGGGCCGCCCCCACACCTACCCGGTCGAGATCCAGGTAGAAGTGATCGACCGCATCGGTATGCTCA AGGATCTGCTCGATCGCCTCGCCAGCGAGCGCATCAACGTGCGCGACGCCCGGGTGAGCACCTACCCCAATTCGACGGCG ATCGTAGACCTCAAAATCGACATCACCGGCAAGCAGCAACTCGATCAAGTCGCCGCCCAGATGGGCAAGATGGCCGACGT GCTCACCGTGCGCTGCCGCCACCGCCACCGGGAATAA
Upstream 100 bases:
>100_bases ACAGTTGTGGGATTCGGATTTATCATAGAGCTAACCTTTCTCAATGGGCGCGCGAAACTGCCGGAGGGTCCTTCGGCAGT TGCTTTGGTCTCTTATTAAT
Downstream 100 bases:
>100_bases CCCGGCGCCGGCGTCCCGGGGCGTCCTCCTCCAGTCCTATGTCCTCGGGTAGAAAAACCGCCAGGCGGCCTATTCACACC GGCTCGTCGGATATCCTGTC
Product: (p)ppGpp 3'-pyrophosphohydrolase
Products: NA
Alternate protein names: Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase [H]
Number of amino acids: Translated: 758; Mature: 758
Protein sequence:
>758_residues MRKGVVGGMHLVSAEFETLQLPDWLKDCLDHPHGTQEWTTANSETSLTTPRTVSLDRGLIARAFDFAYRLHTGQNRASGE PYILHPVQVAGMLRELGSDSAMVAAGFLHDIIEDTATTSEDLEQLFGEQVRLLVEGVTKLSKFTFDSKEERQAENFRRMF LAMAQDIRVIVVKLADRLHNMRTLDFLPTHKQRRIAQETMDIFAPLANRLGIWRFKWELEDLAFKYLDPDAYRHMQKLVS QKRAEREQFIDQVVQTIRAEIDRQHIHGEITGRPKHLWGIYQKMQRQQKEFHEIYDVSAVRIIVEQQEECYRALSIVHNK FRPIPGRFKDYIGLPKPNRYQSLHTAVVGPEGKPLEVQIRTVDMHRIAEYGIAAHWKYKEAGSVVVASQEEKFTWLRQLL DWQSDLKDAGEYLETIKEDLFYSEVYVFTPKGDVVELPRGGTPVDFAYRIHTEVGNRCVGAKVNDRMVPLDSQLKNGDIV EILTSKNSHPSLDWINFVVTSSAKNRIRQWFKRSTREQNIEQGRDMLARELGKGNLENLLKSDRMLKVAQRLNFTTVEDL LAALGYGEVTQASVLNKLQESTPTSTPAEMVELPTQKSAGMPTPSDKPILGIEGIPYHLAKCCNPLPGEPIIGVVTRINR SISIHHHGCPNATKVDPDQLIPVSWNRSYTQPGRPHTYPVEIQVEVIDRIGMLKDLLDRLASERINVRDARVSTYPNSTA IVDLKIDITGKQQLDQVAAQMGKMADVLTVRCRHRHRE
Sequences:
>Translated_758_residues MRKGVVGGMHLVSAEFETLQLPDWLKDCLDHPHGTQEWTTANSETSLTTPRTVSLDRGLIARAFDFAYRLHTGQNRASGE PYILHPVQVAGMLRELGSDSAMVAAGFLHDIIEDTATTSEDLEQLFGEQVRLLVEGVTKLSKFTFDSKEERQAENFRRMF LAMAQDIRVIVVKLADRLHNMRTLDFLPTHKQRRIAQETMDIFAPLANRLGIWRFKWELEDLAFKYLDPDAYRHMQKLVS QKRAEREQFIDQVVQTIRAEIDRQHIHGEITGRPKHLWGIYQKMQRQQKEFHEIYDVSAVRIIVEQQEECYRALSIVHNK FRPIPGRFKDYIGLPKPNRYQSLHTAVVGPEGKPLEVQIRTVDMHRIAEYGIAAHWKYKEAGSVVVASQEEKFTWLRQLL DWQSDLKDAGEYLETIKEDLFYSEVYVFTPKGDVVELPRGGTPVDFAYRIHTEVGNRCVGAKVNDRMVPLDSQLKNGDIV EILTSKNSHPSLDWINFVVTSSAKNRIRQWFKRSTREQNIEQGRDMLARELGKGNLENLLKSDRMLKVAQRLNFTTVEDL LAALGYGEVTQASVLNKLQESTPTSTPAEMVELPTQKSAGMPTPSDKPILGIEGIPYHLAKCCNPLPGEPIIGVVTRINR SISIHHHGCPNATKVDPDQLIPVSWNRSYTQPGRPHTYPVEIQVEVIDRIGMLKDLLDRLASERINVRDARVSTYPNSTA IVDLKIDITGKQQLDQVAAQMGKMADVLTVRCRHRHRE >Mature_758_residues MRKGVVGGMHLVSAEFETLQLPDWLKDCLDHPHGTQEWTTANSETSLTTPRTVSLDRGLIARAFDFAYRLHTGQNRASGE PYILHPVQVAGMLRELGSDSAMVAAGFLHDIIEDTATTSEDLEQLFGEQVRLLVEGVTKLSKFTFDSKEERQAENFRRMF LAMAQDIRVIVVKLADRLHNMRTLDFLPTHKQRRIAQETMDIFAPLANRLGIWRFKWELEDLAFKYLDPDAYRHMQKLVS QKRAEREQFIDQVVQTIRAEIDRQHIHGEITGRPKHLWGIYQKMQRQQKEFHEIYDVSAVRIIVEQQEECYRALSIVHNK FRPIPGRFKDYIGLPKPNRYQSLHTAVVGPEGKPLEVQIRTVDMHRIAEYGIAAHWKYKEAGSVVVASQEEKFTWLRQLL DWQSDLKDAGEYLETIKEDLFYSEVYVFTPKGDVVELPRGGTPVDFAYRIHTEVGNRCVGAKVNDRMVPLDSQLKNGDIV EILTSKNSHPSLDWINFVVTSSAKNRIRQWFKRSTREQNIEQGRDMLARELGKGNLENLLKSDRMLKVAQRLNFTTVEDL LAALGYGEVTQASVLNKLQESTPTSTPAEMVELPTQKSAGMPTPSDKPILGIEGIPYHLAKCCNPLPGEPIIGVVTRINR SISIHHHGCPNATKVDPDQLIPVSWNRSYTQPGRPHTYPVEIQVEVIDRIGMLKDLLDRLASERINVRDARVSTYPNSTA IVDLKIDITGKQQLDQVAAQMGKMADVLTVRCRHRHRE
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into G
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Homo sapiens, GI38348360, Length=127, Percent_Identity=40.9448818897638, Blast_Score=71, Evalue=3e-12, Organism=Escherichia coli, GI1790082, Length=691, Percent_Identity=41.0998552821997, Blast_Score=557, Evalue=1e-159, Organism=Escherichia coli, GI1789147, Length=713, Percent_Identity=37.4474053295933, Blast_Score=505, Evalue=1e-144, Organism=Caenorhabditis elegans, GI25143118, Length=147, Percent_Identity=34.0136054421769, Blast_Score=74, Evalue=2e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =3.1.7.2 [H]
Molecular weight: Translated: 86566; Mature: 86566
Theoretical pI: Translated: 7.60; Mature: 7.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRKGVVGGMHLVSAEFETLQLPDWLKDCLDHPHGTQEWTTANSETSLTTPRTVSLDRGLI CCCCCCCCHHHHHCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCHHH ARAFDFAYRLHTGQNRASGEPYILHPVQVAGMLRELGSDSAMVAAGFLHDIIEDTATTSE HHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH DLEQLFGEQVRLLVEGVTKLSKFTFDSKEERQAENFRRMFLAMAQDIRVIVVKLADRLHN HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC MRTLDFLPTHKQRRIAQETMDIFAPLANRLGIWRFKWELEDLAFKYLDPDAYRHMQKLVS CEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHH QKRAEREQFIDQVVQTIRAEIDRQHIHGEITGRPKHLWGIYQKMQRQQKEFHEIYDVSAV HHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH RIIVEQQEECYRALSIVHNKFRPIPGRFKDYIGLPKPNRYQSLHTAVVGPEGKPLEVQIR HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHEEECCCCCCEEEEEE TVDMHRIAEYGIAAHWKYKEAGSVVVASQEEKFTWLRQLLDWQSDLKDAGEYLETIKEDL EEHHHHHHHHCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FYSEVYVFTPKGDVVELPRGGTPVDFAYRIHTEVGNRCVGAKVNDRMVPLDSQLKNGDIV HHCEEEEECCCCCEEECCCCCCCCEEEEEEEHHHCCEEECCCCCCCCCCCCCCCCCCCEE EILTSKNSHPSLDWINFVVTSSAKNRIRQWFKRSTREQNIEQGRDMLARELGKGNLENLL EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH KSDRMLKVAQRLNFTTVEDLLAALGYGEVTQASVLNKLQESTPTSTPAEMVELPTQKSAG HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC MPTPSDKPILGIEGIPYHLAKCCNPLPGEPIIGVVTRINRSISIHHHGCPNATKVDPDQL CCCCCCCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCHHHE IPVSWNRSYTQPGRPHTYPVEIQVEVIDRIGMLKDLLDRLASERINVRDARVSTYPNSTA EEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEE IVDLKIDITGKQQLDQVAAQMGKMADVLTVRCRHRHRE EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MRKGVVGGMHLVSAEFETLQLPDWLKDCLDHPHGTQEWTTANSETSLTTPRTVSLDRGLI CCCCCCCCHHHHHCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCHHH ARAFDFAYRLHTGQNRASGEPYILHPVQVAGMLRELGSDSAMVAAGFLHDIIEDTATTSE HHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH DLEQLFGEQVRLLVEGVTKLSKFTFDSKEERQAENFRRMFLAMAQDIRVIVVKLADRLHN HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC MRTLDFLPTHKQRRIAQETMDIFAPLANRLGIWRFKWELEDLAFKYLDPDAYRHMQKLVS CEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHCCCHHHHHHHHHHH QKRAEREQFIDQVVQTIRAEIDRQHIHGEITGRPKHLWGIYQKMQRQQKEFHEIYDVSAV HHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH RIIVEQQEECYRALSIVHNKFRPIPGRFKDYIGLPKPNRYQSLHTAVVGPEGKPLEVQIR HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHEEECCCCCCEEEEEE TVDMHRIAEYGIAAHWKYKEAGSVVVASQEEKFTWLRQLLDWQSDLKDAGEYLETIKEDL EEHHHHHHHHCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FYSEVYVFTPKGDVVELPRGGTPVDFAYRIHTEVGNRCVGAKVNDRMVPLDSQLKNGDIV HHCEEEEECCCCCEEECCCCCCCCEEEEEEEHHHCCEEECCCCCCCCCCCCCCCCCCCEE EILTSKNSHPSLDWINFVVTSSAKNRIRQWFKRSTREQNIEQGRDMLARELGKGNLENLL EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH KSDRMLKVAQRLNFTTVEDLLAALGYGEVTQASVLNKLQESTPTSTPAEMVELPTQKSAG HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC MPTPSDKPILGIEGIPYHLAKCCNPLPGEPIIGVVTRINRSISIHHHGCPNATKVDPDQL CCCCCCCCEEECCCCHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCCHHHE IPVSWNRSYTQPGRPHTYPVEIQVEVIDRIGMLKDLLDRLASERINVRDARVSTYPNSTA EEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEE IVDLKIDITGKQQLDQVAAQMGKMADVLTVRCRHRHRE EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]