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The map label for this gene is nanE [H]

Identifier: 37522183

GI number: 37522183

Start: 2768128

End: 2768859

Strand: Direct

Name: nanE [H]

Synonym: glr2614

Alternate gene names: 37522183

Gene position: 2768128-2768859 (Clockwise)

Preceding gene: 37522182

Following gene: 37522184

Centisome position: 59.41

GC content: 69.4

Gene sequence:

>732_bases
ATGAACGCCGTGATCGCCCTGCGGGGGCTGATTGTCTCCTGCCAGGCTCCGGAGGGTTCTCCCCTGCGCGACCCGACGAT
CATCGCCGCCATGGCCGCGAGCGCTTGTTTGAACGGGGCTGTCGCCGTGCGCATCGAATCGCCCGAACACATCCGGGCGG
TGCGCGCCCGCGTGGATGTGCCGATCGTGGGTCTCTGGAAGCGCCCCTACGCGGATAGCGCCGTCTACATCACCCCGACT
TTTGGCGATGCGGCGGCGGTGGCCCAAAGTGGCGCCGATATTGTCGCCATCGACGCCACCGGCAGACCCCGGCCGGGGGG
CGAGTCACTGGCGGAGCTCATTGGGCGCATCCACTGCGAACTGGACAGGCCCGTGCTCGCGGATGTGGCCACCGTGGCCG
AGGGCGAAACGGCCGCCCGCCTCGGTGCCGATATTGTGGTCACGACCCTGTGCGGCTATACCGAGGCGACCCTCGGCACA
CCGCTTCCAGCTTTGGACCTGGTGGGAGCGCTGGCCGGACGGCTTACCGTACCGGTCTGGTGCGAAGGGGGGGTGCAAAG
CCCCGAGCAAGTTGCCCTTGCCTTCGCCCGCGGCGCCCGGGCGGTGGTGGTGGGCACCGCTCTGACGGGCCTCGACGCGC
GCGTGCGCGCCTTTGCCGAGCGGGCCGTGTCGCCCGCGGTGCGGACAGATCCGGGTACGGCTTTTCACAATCGGGCCAAC
CAGTCGCTATGA

Upstream 100 bases:

>100_bases
TCATCTACATCGCCCTTGTCTACGTCCCCCGCGATCAGCGCGCCAAGACCACCGGTTCGCTCGACACCGCCCCCGCCCTC
CTCGCCGTCTCCCGCCCGGG

Downstream 100 bases:

>100_bases
TGTGCTGAATAATCTTTCGGTGAGCGCACTACCATGACCTCCAGCCCGACCGCCGCTGCACGGACCGAAGGGGAAGCCGC
CCCCACCGTGCCGACCCAGG

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNAVIALRGLIVSCQAPEGSPLRDPTIIAAMAASACLNGAVAVRIESPEHIRAVRARVDVPIVGLWKRPYADSAVYITPT
FGDAAAVAQSGADIVAIDATGRPRPGGESLAELIGRIHCELDRPVLADVATVAEGETAARLGADIVVTTLCGYTEATLGT
PLPALDLVGALAGRLTVPVWCEGGVQSPEQVALAFARGARAVVVGTALTGLDARVRAFAERAVSPAVRTDPGTAFHNRAN
QSL

Sequences:

>Translated_243_residues
MNAVIALRGLIVSCQAPEGSPLRDPTIIAAMAASACLNGAVAVRIESPEHIRAVRARVDVPIVGLWKRPYADSAVYITPT
FGDAAAVAQSGADIVAIDATGRPRPGGESLAELIGRIHCELDRPVLADVATVAEGETAARLGADIVVTTLCGYTEATLGT
PLPALDLVGALAGRLTVPVWCEGGVQSPEQVALAFARGARAVVVGTALTGLDARVRAFAERAVSPAVRTDPGTAFHNRAN
QSL
>Mature_243_residues
MNAVIALRGLIVSCQAPEGSPLRDPTIIAAMAASACLNGAVAVRIESPEHIRAVRARVDVPIVGLWKRPYADSAVYITPT
FGDAAAVAQSGADIVAIDATGRPRPGGESLAELIGRIHCELDRPVLADVATVAEGETAARLGADIVVTTLCGYTEATLGT
PLPALDLVGALAGRLTVPVWCEGGVQSPEQVALAFARGARAVVVGTALTGLDARVRAFAERAVSPAVRTDPGTAFHNRAN
QSL

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=205, Percent_Identity=46.8292682926829, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24958; Mature: 24958

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVIALRGLIVSCQAPEGSPLRDPTIIAAMAASACLNGAVAVRIESPEHIRAVRARVDV
CCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC
PIVGLWKRPYADSAVYITPTFGDAAAVAQSGADIVAIDATGRPRPGGESLAELIGRIHCE
CEEEECCCCCCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
LDRPVLADVATVAEGETAARLGADIVVTTLCGYTEATLGTPLPALDLVGALAGRLTVPVW
CCCCHHHHHHHHCCCCHHHHHCCCEEEEHHCCCCHHHCCCCCHHHHHHHHHHCCCEEEEE
CEGGVQSPEQVALAFARGARAVVVGTALTGLDARVRAFAERAVSPAVRTDPGTAFHNRAN
ECCCCCCHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
QSL
CCC
>Mature Secondary Structure
MNAVIALRGLIVSCQAPEGSPLRDPTIIAAMAASACLNGAVAVRIESPEHIRAVRARVDV
CCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC
PIVGLWKRPYADSAVYITPTFGDAAAVAQSGADIVAIDATGRPRPGGESLAELIGRIHCE
CEEEECCCCCCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
LDRPVLADVATVAEGETAARLGADIVVTTLCGYTEATLGTPLPALDLVGALAGRLTVPVW
CCCCHHHHHHHHCCCCHHHHHCCCEEEEHHCCCCHHHCCCCCHHHHHHHHHHCCCEEEEE
CEGGVQSPEQVALAFARGARAVVVGTALTGLDARVRAFAERAVSPAVRTDPGTAFHNRAN
ECCCCCCHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
QSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]