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The map label for this gene is czcB [H]

Identifier: 37522023

GI number: 37522023

Start: 2610237

End: 2611292

Strand: Reverse

Name: czcB [H]

Synonym: gll2454

Alternate gene names: 37522023

Gene position: 2611292-2610237 (Counterclockwise)

Preceding gene: 37522024

Following gene: 37522022

Centisome position: 56.05

GC content: 66.29

Gene sequence:

>1056_bases
GTGCGCAACCAGGCGATTCAGGTGGCCACCGTCAGCCGCAGGCGCGTCTCCGAGCGCAAGGTCTTTCCAGCCTCCGTCGA
GGAGGCGGCTACCCGCTCCGGTACCGTCTCGATGCCGGTCGGTTCGCGCGTGCAGCAAATCAACGTCGACATCGGCGATT
CGGTGCGCAAGGGACAGGTGCTCGCAGTGCTCACCAGCAGCGAACTGGGCGGTGCCAAGGCCGACTTGCTCTCGGCAAAA
GCCAGTCTGCTCGCTTCCCAGGCGCGGCTGATCGCCGCCAAGCGCCAGAGTGACCGCGAGACCTACCTGGCCGGACGGGG
CATCAGCTCCCAAAGGGAACAGCAGGAAGCCCAGGCCCAACTGGCGAGCGCCCAATCGGAGTTTGCGGGCGCCCAATCGG
CAATCGAGGCCGCGAAGGCGCGGCTTCTCGCTTTTGGCCTCACCGAAGAAGAAATCAACCGCCTGCAGCGCGGCAACGAC
ATCACCCCGCGCCTTTCGGCGAGAAGTTCGGTCAACGGCCAGGTTATCCTGCGCAAGGCCCGCGTCGGCCAGGTGGTCCA
ACCGGGCGAAGCGCTTTTTACCATCTCCGATCTTTCGGAAGTCTGGGTGGTGCTCAAGGTCTTCCAGTCGGAACTGGGCC
GCCTGCACGTGGGCGACAGCGTCCGCTTCACCGTGCGCGGCCTCGGCAATACCGAGGTCCAGGGGCGGGTGGTGCGCATC
GGCGAGGCGCTCGACCCCCAGACCCGCGCCGCCGATGTGCGCGTGGTCATCCCCAACCGCGATCGCAAGCTCAAGCCCGG
TATGCTCGTGCAGGCCGAAGTCGACCTGGGCGGCTCCAGCCGCGAGGTACTGGCCGTCCCGGATAAGGCCCTCTACGACG
TGGGCGGCAGGCAAGTGGTTTTCCTGCGCGAATCGACGACGCGCTTTATGCCCCGCGAGGTGCAGCTGGGCACGCGCGTC
GGCGAATACGTCGAGGTGATCGGCGGCCTCAAGCCCGGCGATGCGGTCGTCGTCGAAGGCGGCTTCGTCCTCAAATCCGA
AATGCTCAAATCCTGA

Upstream 100 bases:

>100_bases
GCAGACCAAGGAGGCTGCGGCCGCCGCCGATACCGCCCAGGCAGACAAGACGGCCCTCCAAAGCTCAGGCGAGCGAGCTA
TCGAGCTGTCGCCCGAGGCA

Downstream 100 bases:

>100_bases
TTCGTGAGAAGGTCCATCATGAGCAAACCGGCCCACGAACACCAAAAACCGGCCAACTTCGGCGAAGCCGTGCGCCTGCA
CTTCGCCGAACTGCTCGGTT

Product: cation efflux system membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRNQAIQVATVSRRRVSERKVFPASVEEAATRSGTVSMPVGSRVQQINVDIGDSVRKGQVLAVLTSSELGGAKADLLSAK
ASLLASQARLIAAKRQSDRETYLAGRGISSQREQQEAQAQLASAQSEFAGAQSAIEAAKARLLAFGLTEEEINRLQRGND
ITPRLSARSSVNGQVILRKARVGQVVQPGEALFTISDLSEVWVVLKVFQSELGRLHVGDSVRFTVRGLGNTEVQGRVVRI
GEALDPQTRAADVRVVIPNRDRKLKPGMLVQAEVDLGGSSREVLAVPDKALYDVGGRQVVFLRESTTRFMPREVQLGTRV
GEYVEVIGGLKPGDAVVVEGGFVLKSEMLKS

Sequences:

>Translated_351_residues
MRNQAIQVATVSRRRVSERKVFPASVEEAATRSGTVSMPVGSRVQQINVDIGDSVRKGQVLAVLTSSELGGAKADLLSAK
ASLLASQARLIAAKRQSDRETYLAGRGISSQREQQEAQAQLASAQSEFAGAQSAIEAAKARLLAFGLTEEEINRLQRGND
ITPRLSARSSVNGQVILRKARVGQVVQPGEALFTISDLSEVWVVLKVFQSELGRLHVGDSVRFTVRGLGNTEVQGRVVRI
GEALDPQTRAADVRVVIPNRDRKLKPGMLVQAEVDLGGSSREVLAVPDKALYDVGGRQVVFLRESTTRFMPREVQLGTRV
GEYVEVIGGLKPGDAVVVEGGFVLKSEMLKS
>Mature_351_residues
MRNQAIQVATVSRRRVSERKVFPASVEEAATRSGTVSMPVGSRVQQINVDIGDSVRKGQVLAVLTSSELGGAKADLLSAK
ASLLASQARLIAAKRQSDRETYLAGRGISSQREQQEAQAQLASAQSEFAGAQSAIEAAKARLLAFGLTEEEINRLQRGND
ITPRLSARSSVNGQVILRKARVGQVVQPGEALFTISDLSEVWVVLKVFQSELGRLHVGDSVRFTVRGLGNTEVQGRVVRI
GEALDPQTRAADVRVVIPNRDRKLKPGMLVQAEVDLGGSSREVLAVPDKALYDVGGRQVVFLRESTTRFMPREVQLGTRV
GEYVEVIGGLKPGDAVVVEGGFVLKSEMLKS

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=347, Percent_Identity=23.6311239193084, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081796, Length=330, Percent_Identity=27.5757575757576, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37836; Mature: 37836

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNQAIQVATVSRRRVSERKVFPASVEEAATRSGTVSMPVGSRVQQINVDIGDSVRKGQV
CCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCE
LAVLTSSELGGAKADLLSAKASLLASQARLIAAKRQSDRETYLAGRGISSQREQQEAQAQ
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHH
LASAQSEFAGAQSAIEAAKARLLAFGLTEEEINRLQRGNDITPRLSARSSVNGQVILRKA
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
RVGQVVQPGEALFTISDLSEVWVVLKVFQSELGRLHVGDSVRFTVRGLGNTEVQGRVVRI
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEECCCCEEEEEEECCCCCCCCEEEEE
GEALDPQTRAADVRVVIPNRDRKLKPGMLVQAEVDLGGSSREVLAVPDKALYDVGGRQVV
CCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHHHCCCCCEEE
FLRESTTRFMPREVQLGTRVGEYVEVIGGLKPGDAVVVEGGFVLKSEMLKS
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEHHHHHCC
>Mature Secondary Structure
MRNQAIQVATVSRRRVSERKVFPASVEEAATRSGTVSMPVGSRVQQINVDIGDSVRKGQV
CCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCE
LAVLTSSELGGAKADLLSAKASLLASQARLIAAKRQSDRETYLAGRGISSQREQQEAQAQ
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCHHHHHHHHHHH
LASAQSEFAGAQSAIEAAKARLLAFGLTEEEINRLQRGNDITPRLSARSSVNGQVILRKA
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEC
RVGQVVQPGEALFTISDLSEVWVVLKVFQSELGRLHVGDSVRFTVRGLGNTEVQGRVVRI
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCEEECCCCEEEEEEECCCCCCCCEEEEE
GEALDPQTRAADVRVVIPNRDRKLKPGMLVQAEVDLGGSSREVLAVPDKALYDVGGRQVV
CCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEECCCHHHHCCCCCEEE
FLRESTTRFMPREVQLGTRVGEYVEVIGGLKPGDAVVVEGGFVLKSEMLKS
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]