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The map label for this gene is czcC [H]

Identifier: 37522024

GI number: 37522024

Start: 2611469

End: 2612770

Strand: Reverse

Name: czcC [H]

Synonym: gll2455

Alternate gene names: 37522024

Gene position: 2612770-2611469 (Counterclockwise)

Preceding gene: 37522025

Following gene: 37522023

Centisome position: 56.08

GC content: 66.28

Gene sequence:

>1302_bases
ATGATCCAGAGTTTGGTTAGCCGCCGGTACCGCCGGTTGGGTGAAGTATTGATGGCCCTGTGCGTGGCAGGCGGTTATCT
GTCGACGGCGGCGCTGGCCCAGGGGGTTCCCGAGCCGCCGGTGCTCTCCGGTCGCGCGACGCTCACCATCGAGGAGGCGG
TGGACCGCGCCTCCAGCGTCTCGCCGGAGTTGCGCTCGTTTCGCTCGGGCGTCGACATTGCCCAGGGCGATGTGATCACT
TCGCGTCTGCCCAGCCGCTTCAACCCGGGGGTGTCCCTGGAGGCCGGTCCGCGCCTCAACACCCTCGCCGATGCGTCTGC
CTTGCAGTTTGGCGTCACCGTCGCCCAAGAACTCGACCGGCCCGAAAAGCGCGCTGCCCGCGAGCAGGTGGCGCTGCTGG
GCTTTCAGGTGGAGCAGGCCCAGTTGCAGGCTGCCCGCCTGCGCCTCGAGCTGCGCGTTCGCACCTTCTATTCGCAATTT
TGGCTCAGCGAGCAACTCCTCAAGCTCGCCGTCGAGCGCGAACAGTTGGCGACCCGCTCGCTCACCGCGCTGCAGGAGCG
CTACAAAGTCGGCGATATCAGTTTGATCCCCGTCAATCTGGCCCAGGTGGAACTCTCCGTCTCACGCGCCCAACGCGAAA
GGCAAGAAGGAGAAGCGGCGGCGAGCCGTGCCGCTTTGCTGGTCGCCGTCGGCGAGCCGCCCGAGCGTTCCGTACAGCCC
CAGGCGGCGTTGCCCGCCGCTCCGCTCGAACTACCGGAACTGCCGCGCATTTTCCAGTTGGTCATCGAAGCCAACCCGGT
GCTGCTGGCCTCCGAGACCGAGCGCCGCCGCAGCGAGGCGCAGGTGCAGCTTGCCCAGGCGGAGGCCCTGCCGAACCTCT
CGCCGCTGGTGAGCTACCGTCGGGAAGGACCGGAGAATATCGTCGTGGCGGGCTTGAGCGTACCTATCAACCTGTTCAAC
CGCAACCAGGGCACTATTTTTAGCGCCGAGGCCCGTCGCACCCAAACGGCGGCGCTGCGCGAGCAGCGCGCTCTGGAGTT
GCGCACCCAGGTCGAGGAGGCCTACGCCCGCTACAACGCCGCCCGCCGGGTGCTCCAGACCTACACAGGTGATACGATCG
CGGCTATCGAGCGCAACCAGGGACTAGTCGAAGAAGGTTTTCGCGCCGGCAAGACGGGGGTGACCGAAGTGCTCCTTGCC
CGCCGCGACGGCCTCAATGCCCGCTCGGCCTTCCTGCAGGCGCAAGCAGATCTGTACACCAGCTATGTCCAGCTGCAAAA
TGCTACCGGAGGACGTCTTTGA

Upstream 100 bases:

>100_bases
GAGCCACCGCAAAAGCCATGAACAAAAGTGCTCAAATGTAAAGTCTTGTAAAACAAACAGGGCAACTGTACATTGATCAA
TAGACTTGCGCTCAATTGAA

Downstream 100 bases:

>100_bases
GAAGCTATCGGATTTTCCTTGCCGCCGCCCTGGCTGCGGTTGCGCTCACCGCCTGCGGTACAGCGGAGGCGGATAAGCAG
ACCAAGGAGGCTGCGGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIQSLVSRRYRRLGEVLMALCVAGGYLSTAALAQGVPEPPVLSGRATLTIEEAVDRASSVSPELRSFRSGVDIAQGDVIT
SRLPSRFNPGVSLEAGPRLNTLADASALQFGVTVAQELDRPEKRAAREQVALLGFQVEQAQLQAARLRLELRVRTFYSQF
WLSEQLLKLAVEREQLATRSLTALQERYKVGDISLIPVNLAQVELSVSRAQRERQEGEAAASRAALLVAVGEPPERSVQP
QAALPAAPLELPELPRIFQLVIEANPVLLASETERRRSEAQVQLAQAEALPNLSPLVSYRREGPENIVVAGLSVPINLFN
RNQGTIFSAEARRTQTAALREQRALELRTQVEEAYARYNAARRVLQTYTGDTIAAIERNQGLVEEGFRAGKTGVTEVLLA
RRDGLNARSAFLQAQADLYTSYVQLQNATGGRL

Sequences:

>Translated_433_residues
MIQSLVSRRYRRLGEVLMALCVAGGYLSTAALAQGVPEPPVLSGRATLTIEEAVDRASSVSPELRSFRSGVDIAQGDVIT
SRLPSRFNPGVSLEAGPRLNTLADASALQFGVTVAQELDRPEKRAAREQVALLGFQVEQAQLQAARLRLELRVRTFYSQF
WLSEQLLKLAVEREQLATRSLTALQERYKVGDISLIPVNLAQVELSVSRAQRERQEGEAAASRAALLVAVGEPPERSVQP
QAALPAAPLELPELPRIFQLVIEANPVLLASETERRRSEAQVQLAQAEALPNLSPLVSYRREGPENIVVAGLSVPINLFN
RNQGTIFSAEARRTQTAALREQRALELRTQVEEAYARYNAARRVLQTYTGDTIAAIERNQGLVEEGFRAGKTGVTEVLLA
RRDGLNARSAFLQAQADLYTSYVQLQNATGGRL
>Mature_433_residues
MIQSLVSRRYRRLGEVLMALCVAGGYLSTAALAQGVPEPPVLSGRATLTIEEAVDRASSVSPELRSFRSGVDIAQGDVIT
SRLPSRFNPGVSLEAGPRLNTLADASALQFGVTVAQELDRPEKRAAREQVALLGFQVEQAQLQAARLRLELRVRTFYSQF
WLSEQLLKLAVEREQLATRSLTALQERYKVGDISLIPVNLAQVELSVSRAQRERQEGEAAASRAALLVAVGEPPERSVQP
QAALPAAPLELPELPRIFQLVIEANPVLLASETERRRSEAQVQLAQAEALPNLSPLVSYRREGPENIVVAGLSVPINLFN
RNQGTIFSAEARRTQTAALREQRALELRTQVEEAYARYNAARRVLQTYTGDTIAAIERNQGLVEEGFRAGKTGVTEVLLA
RRDGLNARSAFLQAQADLYTSYVQLQNATGGRL

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47440; Mature: 47440

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQSLVSRRYRRLGEVLMALCVAGGYLSTAALAQGVPEPPVLSGRATLTIEEAVDRASSV
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCC
SPELRSFRSGVDIAQGDVITSRLPSRFNPGVSLEAGPRLNTLADASALQFGVTVAQELDR
CHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PEKRAAREQVALLGFQVEQAQLQAARLRLELRVRTFYSQFWLSEQLLKLAVEREQLATRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALQERYKVGDISLIPVNLAQVELSVSRAQRERQEGEAAASRAALLVAVGEPPERSVQP
HHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
QAALPAAPLELPELPRIFQLVIEANPVLLASETERRRSEAQVQLAQAEALPNLSPLVSYR
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REGPENIVVAGLSVPINLFNRNQGTIFSAEARRTQTAALREQRALELRTQVEEAYARYNA
HCCCCCEEEEECCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRVLQTYTGDTIAAIERNQGLVEEGFRAGKTGVTEVLLARRDGLNARSAFLQAQADLYT
HHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SYVQLQNATGGRL
HHHHHCCCCCCCC
>Mature Secondary Structure
MIQSLVSRRYRRLGEVLMALCVAGGYLSTAALAQGVPEPPVLSGRATLTIEEAVDRASSV
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCC
SPELRSFRSGVDIAQGDVITSRLPSRFNPGVSLEAGPRLNTLADASALQFGVTVAQELDR
CHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PEKRAAREQVALLGFQVEQAQLQAARLRLELRVRTFYSQFWLSEQLLKLAVEREQLATRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALQERYKVGDISLIPVNLAQVELSVSRAQRERQEGEAAASRAALLVAVGEPPERSVQP
HHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCC
QAALPAAPLELPELPRIFQLVIEANPVLLASETERRRSEAQVQLAQAEALPNLSPLVSYR
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
REGPENIVVAGLSVPINLFNRNQGTIFSAEARRTQTAALREQRALELRTQVEEAYARYNA
HCCCCCEEEEECCCEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRVLQTYTGDTIAAIERNQGLVEEGFRAGKTGVTEVLLARRDGLNARSAFLQAQADLYT
HHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SYVQLQNATGGRL
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]