Click here to switch to the map view.

The map label for this gene is pilQ [H]

Identifier: 37522007

GI number: 37522007

Start: 2593240

End: 2594721

Strand: Direct

Name: pilQ [H]

Synonym: glr2438

Alternate gene names: 37522007

Gene position: 2593240-2594721 (Clockwise)

Preceding gene: 37522006

Following gene: 37522010

Centisome position: 55.66

GC content: 65.52

Gene sequence:

>1482_bases
GTGATGAATGGCTCGAAGTCTTGGTGTGTGGGCCTGGCGCTGCTTCTGGGGGTTGGGGCGGCGGCGGCCGAAGAACCGTT
ACCCCGCCTGCGCACCCGGGCGGTCGCCCCGCCTGCGGGTGATATTGCCGGGGAGGAAATCCCCCTGGGCCGGCCGGTGG
AACTGGGGAGCGGCGAACGGGTCACCCTGGCGCTCAAGGACGCACCGGTCAGAGAGGTGCTGCAGATTTTGGCCCGCCGG
GCCGGGTGCAACGTGCTCTTTGGCGAGGGGGTCAGCGCTCAGCGCGTCTCGATGGATGTGCGCGGCGAGACCCTCGACGA
TACGTTCAACTTGGTGCTGCACCTGCACAACCTCAAAGCCCGCCGCACCGGCAACACCATCCTGGTGGGCGGCGAGATGG
CCCACAACCTCCCCCAGACCCGCATGCGCACCTTTCGCCTCAACCAGGCCGATGTGCAGCAGGCAGCCGGGGTACTGCGC
GGGCTGGGCGCCCAGGTGGGTTCAACCAACCTCGGCAGTACCCAACCGGGTGCAGCGACCACCAACCCCGATCCTGCTGC
TACCAGCGGTCCGTTGCGCGGTGAGCTGTTTGTCACCGTCGATGCGCGTACCAATTCGCTGGTGGCCGTCGGCAGCCCCC
GCGCCCTGCAGATTGCCCAGGTGCAACTCGCCCAACTCGACGTGCGCCAGCGCCAGGTGATGATCGACGTCAAACTCGTC
GATGTCAATCTCAACAACGTCAGCGATCTGGGTTTTCGCCTCGGTGGCTCGGCAGGTAACTTCCAGCTGGGCACGGTGGG
GGGTGCTGCCGATCTGGGCGCTTCGTACCCGGCGGCGGTGGGCCTCACCGGCGGTGGGCCGGGTAACACGCTCATCTTCA
ACACCCTGGGCGCCCTCGCCTCGGCGATGGCCCTGCGCCTCGACACGGCCATCCAGGAAGGGTCCGCCCGGGTGCTCGCT
TCTCCCCAATTGCTCGTCGCCTCCGGGGCCGGTTTTTCGAAGCCCACCGCCGCCCGCGTCGAAATTACCGATGACGTGGT
CGTGGGGGCAACGATTACCACCGACCGGGAAACCGGTCAGAGCACCACCACCATCAAAGTCGACAAAGTCGGCGTCAGCC
TGGAGATCGCCGTCTATCAAGTCGACGACAACGGCTTTGTCGATGTCTCCCTCAAGCCGCAGGTCAGTTCCATCAACGAC
ATCCAGCGCGACGCGGCGGGGAATCTGGTCACCCTGCTCACCCGCCGCAACCTGGATATCCAGCGGCTGCGGCTGCGCGA
CGGCGAAACCTTCGTGATCGGCGGCGTCATCCGCGAAATCGACCGCCAACTGGTCCAGAAAATGCCGCTGCTGGGAGACT
TGCCGGTGCTGGGTGCTTTGTTTCGCTTCCAAAGCAACCAACACGAGCGGCGCGAAGTGGCGCTGATGGTGACTCCCCAC
ATCTTGAAAGAATCGGTCCATGAGGCGGCTCCCCTGCGATAA

Upstream 100 bases:

>100_bases
GGGTCGGGACGGCCGTAGTACAGAATGTTTCGGCGCAGACGGGTCAGGTGAGCTTCCGGCAGGGAAGCAGGCGGATGGTG
CGCACCCTGGAGGCCCGACC

Downstream 100 bases:

>100_bases
CTGGGTGGGGACACAGGCCGACAAACCCGTGGTTCATCAATGGAAATGCCGGCTTTGCCCTACTTCCCGAACGGGGGCCT
GATGGCGGTGAAGCGTTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Outer membrane protein omc [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MMNGSKSWCVGLALLLGVGAAAAEEPLPRLRTRAVAPPAGDIAGEEIPLGRPVELGSGERVTLALKDAPVREVLQILARR
AGCNVLFGEGVSAQRVSMDVRGETLDDTFNLVLHLHNLKARRTGNTILVGGEMAHNLPQTRMRTFRLNQADVQQAAGVLR
GLGAQVGSTNLGSTQPGAATTNPDPAATSGPLRGELFVTVDARTNSLVAVGSPRALQIAQVQLAQLDVRQRQVMIDVKLV
DVNLNNVSDLGFRLGGSAGNFQLGTVGGAADLGASYPAAVGLTGGGPGNTLIFNTLGALASAMALRLDTAIQEGSARVLA
SPQLLVASGAGFSKPTAARVEITDDVVVGATITTDRETGQSTTTIKVDKVGVSLEIAVYQVDDNGFVDVSLKPQVSSIND
IQRDAAGNLVTLLTRRNLDIQRLRLRDGETFVIGGVIREIDRQLVQKMPLLGDLPVLGALFRFQSNQHERREVALMVTPH
ILKESVHEAAPLR

Sequences:

>Translated_493_residues
MMNGSKSWCVGLALLLGVGAAAAEEPLPRLRTRAVAPPAGDIAGEEIPLGRPVELGSGERVTLALKDAPVREVLQILARR
AGCNVLFGEGVSAQRVSMDVRGETLDDTFNLVLHLHNLKARRTGNTILVGGEMAHNLPQTRMRTFRLNQADVQQAAGVLR
GLGAQVGSTNLGSTQPGAATTNPDPAATSGPLRGELFVTVDARTNSLVAVGSPRALQIAQVQLAQLDVRQRQVMIDVKLV
DVNLNNVSDLGFRLGGSAGNFQLGTVGGAADLGASYPAAVGLTGGGPGNTLIFNTLGALASAMALRLDTAIQEGSARVLA
SPQLLVASGAGFSKPTAARVEITDDVVVGATITTDRETGQSTTTIKVDKVGVSLEIAVYQVDDNGFVDVSLKPQVSSIND
IQRDAAGNLVTLLTRRNLDIQRLRLRDGETFVIGGVIREIDRQLVQKMPLLGDLPVLGALFRFQSNQHERREVALMVTPH
ILKESVHEAAPLR
>Mature_493_residues
MMNGSKSWCVGLALLLGVGAAAAEEPLPRLRTRAVAPPAGDIAGEEIPLGRPVELGSGERVTLALKDAPVREVLQILARR
AGCNVLFGEGVSAQRVSMDVRGETLDDTFNLVLHLHNLKARRTGNTILVGGEMAHNLPQTRMRTFRLNQADVQQAAGVLR
GLGAQVGSTNLGSTQPGAATTNPDPAATSGPLRGELFVTVDARTNSLVAVGSPRALQIAQVQLAQLDVRQRQVMIDVKLV
DVNLNNVSDLGFRLGGSAGNFQLGTVGGAADLGASYPAAVGLTGGGPGNTLIFNTLGALASAMALRLDTAIQEGSARVLA
SPQLLVASGAGFSKPTAARVEITDDVVVGATITTDRETGQSTTTIKVDKVGVSLEIAVYQVDDNGFVDVSLKPQVSSIND
IQRDAAGNLVTLLTRRNLDIQRLRLRDGETFVIGGVIREIDRQLVQKMPLLGDLPVLGALFRFQSNQHERREVALMVTPH
ILKESVHEAAPLR

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane. Note=Associated to the membrane through its C-terminus [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=448, Percent_Identity=25.4464285714286, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082242, Length=353, Percent_Identity=24.0793201133144, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 51947; Mature: 51947

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNGSKSWCVGLALLLGVGAAAAEEPLPRLRTRAVAPPAGDIAGEEIPLGRPVELGSGER
CCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCE
VTLALKDAPVREVLQILARRAGCNVLFGEGVSAQRVSMDVRGETLDDTFNLVLHLHNLKA
EEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCHHHHEEEHEEEECCCC
RRTGNTILVGGEMAHNLPQTRMRTFRLNQADVQQAAGVLRGLGAQVGSTNLGSTQPGAAT
CCCCCEEEECCHHHHCCCHHHHHEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
TNPDPAATSGPLRGELFVTVDARTNSLVAVGSPRALQIAQVQLAQLDVRQRQVMIDVKLV
CCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCEEEHHHHHHHHHHHCCEEEEEEEEEE
DVNLNNVSDLGFRLGGSAGNFQLGTVGGAADLGASYPAAVGLTGGGPGNTLIFNTLGALA
EEECCCCHHCCEEECCCCCCEEEEECCCHHHCCCCCCCEEEECCCCCCCEEEHHHHHHHH
SAMALRLDTAIQEGSARVLASPQLLVASGAGFSKPTAARVEITDDVVVGATITTDRETGQ
HHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCEEEEEEECCEEEEEEEECCCCCCC
STTTIKVDKVGVSLEIAVYQVDDNGFVDVSLKPQVSSINDIQRDAAGNLVTLLTRRNLDI
CEEEEEEEEECEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCE
QRLRLRDGETFVIGGVIREIDRQLVQKMPLLGDLPVLGALFRFQSNQHERREVALMVTPH
EEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECHH
ILKESVHEAAPLR
HHHHHHHHHCCCC
>Mature Secondary Structure
MMNGSKSWCVGLALLLGVGAAAAEEPLPRLRTRAVAPPAGDIAGEEIPLGRPVELGSGER
CCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCE
VTLALKDAPVREVLQILARRAGCNVLFGEGVSAQRVSMDVRGETLDDTFNLVLHLHNLKA
EEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCEEEEEEECCCCHHHHEEEHEEEECCCC
RRTGNTILVGGEMAHNLPQTRMRTFRLNQADVQQAAGVLRGLGAQVGSTNLGSTQPGAAT
CCCCCEEEECCHHHHCCCHHHHHEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
TNPDPAATSGPLRGELFVTVDARTNSLVAVGSPRALQIAQVQLAQLDVRQRQVMIDVKLV
CCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCEEEHHHHHHHHHHHCCEEEEEEEEEE
DVNLNNVSDLGFRLGGSAGNFQLGTVGGAADLGASYPAAVGLTGGGPGNTLIFNTLGALA
EEECCCCHHCCEEECCCCCCEEEEECCCHHHCCCCCCCEEEECCCCCCCEEEHHHHHHHH
SAMALRLDTAIQEGSARVLASPQLLVASGAGFSKPTAARVEITDDVVVGATITTDRETGQ
HHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCEEEEEEECCEEEEEEEECCCCCCC
STTTIKVDKVGVSLEIAVYQVDDNGFVDVSLKPQVSSINDIQRDAAGNLVTLLTRRNLDI
CEEEEEEEEECEEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCE
QRLRLRDGETFVIGGVIREIDRQLVQKMPLLGDLPVLGALFRFQSNQHERREVALMVTPH
EEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECHH
ILKESVHEAAPLR
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA