| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is dxr
Identifier: 37521821
GI number: 37521821
Start: 2413353
End: 2414531
Strand: Reverse
Name: dxr
Synonym: gll2252
Alternate gene names: 37521821
Gene position: 2414531-2413353 (Counterclockwise)
Preceding gene: 37521822
Following gene: 37521818
Centisome position: 51.82
GC content: 66.75
Gene sequence:
>1179_bases GTGAAGCATATCGCTCTGCTCGGCTCCACCGGCTCGATCGGCACCCAGACCCTCGATATTGTCGCCGAGTACCCGGAGCG CTTTGCTGTGACCGGCATGACCGCCCACAGCAATATGGAACTGTTGGCCGAGCAGATCCGCCGCTTCCGGCCCCAGGTGG TGGCGGTGGGCAGCGAGGCGAGGCGTGCGGCTCTGGCGGCCTTGCTGGCGGGTTTTGACGGCATGCCCGAAATGTTTGTC GGCGAAAAAGGCTGCTGCACGGTCGCTTCCCAGGCTCCCGCCGAAGTGGTGGTCACCGGCATCGTCGGTTGCGCCGGGCT GATGCCCACCCTGGCGGCCGTCGATGCGGGCCGGGATCTGGCCCTCGCCAACAAAGAGACGCTGGTGGCGGGTGGACCGG TGGTGATGCCGCGCATCCGCGCGCGGGGGGTGAAGCTGCTGCCGGTCGATTCGGAGCACTCGGCCATCTTCCAGTGTCTG CAGGGGGTGCCCGAGGGCGCTCTCAAGCGCATCTTGCTCACCGCCTCGGGCGGGGCCTTTCGCGACTGGCCGGTGGAGAA GCTGGCCGAGGCGACCACGGCGGACGCCCTCAAGCACCCCAATTGGGTGATGGGAGCCAAGATCACCGTCGATTCGGCCA CCTTGATGAACAAGGGCCTGGAGGTGATCGAGGCGCACTGGCTCTTCGGGCTGGACTACGACCGGATCGAGATCGTCATC CACCCCCAGAGCATCGTGCACTCGCTCGTCGAACTGGCCGACACTTCGGTCGTCGCCCAACTCGGCTGGCCCGATATGCG CCTGCCGATCTTGTATGCCCTCAGTTGGCCCGAGCGCCTCGCCACCCCCTGGAAGCCTCTGGATCTCGCCCGGGTGGGCA CCCTCACCTTCAAAGAGCCCGACCACGAGCGCTACCCCAATATGCGGCTGGCCTACCAGGCCGGGCGGGCCGGCGGCACC TACCCGACGGTGCTCAACGCCGCCAACGAAGAGGCCGTCGCCCAGTTTCTCCAAGAAAAAGTCCGCTTTCTGGAGATGTC GCGCCTGCTCGAAGCCACCCTCGAAGCCCACAAAAGCGCCGGCGAACCCGATCTCGACGATGTGTGCGGAGCCGATCGCT GGGCGCGCGAGCACGTGCGCTGGCTGGTGGAGCGCTCGCCGGCGCGGGTACTGATTTAA
Upstream 100 bases:
>100_bases GTTTCATGTGTCCGGTGTCCGTAAGTGCACCCCGATACCCATCCGCTTGCCAGTCATCCGCGCGCACGGGACAATACCGG TTAGTTGCTGGTAAATCTTT
Downstream 100 bases:
>100_bases AGCTTGCCGATTTCCCGCCGGGAGACCACGACGGTGTGCTCCCAGCCGTCTACCTGAACGGTGATGCCGCCGAAGGCGCC GAAGCCGACGACAGTCGCGG
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 392; Mature: 392
Protein sequence:
>392_residues MKHIALLGSTGSIGTQTLDIVAEYPERFAVTGMTAHSNMELLAEQIRRFRPQVVAVGSEARRAALAALLAGFDGMPEMFV GEKGCCTVASQAPAEVVVTGIVGCAGLMPTLAAVDAGRDLALANKETLVAGGPVVMPRIRARGVKLLPVDSEHSAIFQCL QGVPEGALKRILLTASGGAFRDWPVEKLAEATTADALKHPNWVMGAKITVDSATLMNKGLEVIEAHWLFGLDYDRIEIVI HPQSIVHSLVELADTSVVAQLGWPDMRLPILYALSWPERLATPWKPLDLARVGTLTFKEPDHERYPNMRLAYQAGRAGGT YPTVLNAANEEAVAQFLQEKVRFLEMSRLLEATLEAHKSAGEPDLDDVCGADRWAREHVRWLVERSPARVLI
Sequences:
>Translated_392_residues MKHIALLGSTGSIGTQTLDIVAEYPERFAVTGMTAHSNMELLAEQIRRFRPQVVAVGSEARRAALAALLAGFDGMPEMFV GEKGCCTVASQAPAEVVVTGIVGCAGLMPTLAAVDAGRDLALANKETLVAGGPVVMPRIRARGVKLLPVDSEHSAIFQCL QGVPEGALKRILLTASGGAFRDWPVEKLAEATTADALKHPNWVMGAKITVDSATLMNKGLEVIEAHWLFGLDYDRIEIVI HPQSIVHSLVELADTSVVAQLGWPDMRLPILYALSWPERLATPWKPLDLARVGTLTFKEPDHERYPNMRLAYQAGRAGGT YPTVLNAANEEAVAQFLQEKVRFLEMSRLLEATLEAHKSAGEPDLDDVCGADRWAREHVRWLVERSPARVLI >Mature_392_residues MKHIALLGSTGSIGTQTLDIVAEYPERFAVTGMTAHSNMELLAEQIRRFRPQVVAVGSEARRAALAALLAGFDGMPEMFV GEKGCCTVASQAPAEVVVTGIVGCAGLMPTLAAVDAGRDLALANKETLVAGGPVVMPRIRARGVKLLPVDSEHSAIFQCL QGVPEGALKRILLTASGGAFRDWPVEKLAEATTADALKHPNWVMGAKITVDSATLMNKGLEVIEAHWLFGLDYDRIEIVI HPQSIVHSLVELADTSVVAQLGWPDMRLPILYALSWPERLATPWKPLDLARVGTLTFKEPDHERYPNMRLAYQAGRAGGT YPTVLNAANEEAVAQFLQEKVRFLEMSRLLEATLEAHKSAGEPDLDDVCGADRWAREHVRWLVERSPARVLI
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=395, Percent_Identity=44.0506329113924, Blast_Score=318, Evalue=4e-88,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_GLOVI (Q7NID1)
Other databases:
- EMBL: BA000045 - RefSeq: NP_925198.1 - ProteinModelPortal: Q7NID1 - SMR: Q7NID1 - GeneID: 2600654 - GenomeReviews: BA000045_GR - KEGG: gvi:gll2252 - NMPDR: fig|251221.1.peg.2252 - HOGENOM: HBG430762 - OMA: IHSMVEY - ProtClustDB: PRK05447 - BioCyc: GVIO251221:GLL2252-MONOMER - BRENDA: 1.1.1.267 - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 42605; Mature: 42605
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: NA
Important sites: BINDING 125-125 BINDING 152-152 BINDING 176-176 BINDING 199-199 BINDING 221-221
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHIALLGSTGSIGTQTLDIVAEYPERFAVTGMTAHSNMELLAEQIRRFRPQVVAVGSEA CCEEEEEECCCCCCHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHCCCEEEEECCHH RRAALAALLAGFDGMPEMFVGEKGCCTVASQAPAEVVVTGIVGCAGLMPTLAAVDAGRDL HHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE ALANKETLVAGGPVVMPRIRARGVKLLPVDSEHSAIFQCLQGVPEGALKRILLTASGGAF EECCCCEEEECCCEEECHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHEEEEEECCCCC RDWPVEKLAEATTADALKHPNWVMGAKITVDSATLMNKGLEVIEAHWLFGLDYDRIEIVI CCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHCCHHHHHHHHHCCCCCCEEEEEE HPQSIVHSLVELADTSVVAQLGWPDMRLPILYALSWPERLATPWKPLDLARVGTLTFKEP CCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCHHHHCCCCCCCCHHHHCEEEECCC DHERYPNMRLAYQAGRAGGTYPTVLNAANEEAVAQFLQEKVRFLEMSRLLEATLEAHKSA CHHHCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC GEPDLDDVCGADRWAREHVRWLVERSPARVLI CCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCC >Mature Secondary Structure MKHIALLGSTGSIGTQTLDIVAEYPERFAVTGMTAHSNMELLAEQIRRFRPQVVAVGSEA CCEEEEEECCCCCCHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHCCCEEEEECCHH RRAALAALLAGFDGMPEMFVGEKGCCTVASQAPAEVVVTGIVGCAGLMPTLAAVDAGRDL HHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE ALANKETLVAGGPVVMPRIRARGVKLLPVDSEHSAIFQCLQGVPEGALKRILLTASGGAF EECCCCEEEECCCEEECHHHHCCEEEEECCCCHHHHHHHHHCCCHHHHHEEEEEECCCCC RDWPVEKLAEATTADALKHPNWVMGAKITVDSATLMNKGLEVIEAHWLFGLDYDRIEIVI CCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHHCCHHHHHHHHHCCCCCCEEEEEE HPQSIVHSLVELADTSVVAQLGWPDMRLPILYALSWPERLATPWKPLDLARVGTLTFKEP CCHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCHHHHCCCCCCCCHHHHCEEEECCC DHERYPNMRLAYQAGRAGGTYPTVLNAANEEAVAQFLQEKVRFLEMSRLLEATLEAHKSA CHHHCCCCEEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC GEPDLDDVCGADRWAREHVRWLVERSPARVLI CCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 14621292