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The map label for this gene is rhbA [H]

Identifier: 37521792

GI number: 37521792

Start: 2378776

End: 2380227

Strand: Reverse

Name: rhbA [H]

Synonym: gll2223

Alternate gene names: 37521792

Gene position: 2380227-2378776 (Counterclockwise)

Preceding gene: 37521793

Following gene: 37521791

Centisome position: 51.09

GC content: 63.57

Gene sequence:

>1452_bases
GTGCGCAGAGCCGCAGGCGATCGGCCGGTGGCCGGGCCAATGCGCGAGCTTTTGCAAGGTCCTGGAGTCGAAAACCCACC
AGCGTCATCAGGTCCTTACTTACAGCGGCAGGCCCAGCGCGAATCCAACGCCCGCAGTTATCCCCGACGTATCCCATTCG
CTTTCAAGAAGGCCGAGGGGGTCTACCTGACAAGTGTCGAGGGCAAGCAATACATCGACTGCCTGGCCGGAGCCGGGGCG
CTTCCGTTAGGACACAACCACCCGGTTGCTATTCAAGCCATCCAAACCGTGATCCGGGGTAAGTTCCCCCTGCTCACGCT
CGACTTGCCCACTCCCCTCAAAGACCGATTCGTCGATGAACTCTTCGCCTGCCTGCCTGCCGAGTTTGCTCGCAACGCCC
GGATCCAGTTTTGTAGCCCCGCCGGCACCGATGCCGTCGAGGCTGCCCTGAAGCTTGTGAAAACGGCCACTGCACGACGC
GGCATCCTCTCGTTCCAGGGGGCCTACCACGGCATGTCCCACGGCTCGCTCAGCCTGACGGGCAACCTGGCAGCCAAGGT
CGTGCCGAACCTGATGCCTGAGGTGCAGTTCCTACCCTATCCCTACGAGTTGCGCTGTCCCTTCGGCCTGGGCGGTGAAG
TCGGCTACCGCACGGGCCTGCACTACATCGAGAACTTGCTCAAAGACCCCGAGGGCGGCGTCCCTTCCCCGGCAGGGATC
ATCCTGGAGGTGGTGCAGGGCGAAGGGGGGGTGATTCCTGCCCCGGACGAGTGGCTGCGAGGGTTGCGCCGGATCACCCA
GGAGCAGCAAATCCCCTTGATCGTAGACGAGATCCAGACGGGCTTTGGCCGGACGGGTAAACTCTTTGCCTTCGAGCACA
GCGGCATTGTTCCAGATGTGCTCCTGCTCTCGAAGGCGATCGGTGGTGGTCTACCCCTGGCGGTAGTGGTCTACCGCGAA
TCCCTCGACCGCTGGCAACCTGGAGCCCACGCGGGCACGTTCCGGGGGAACCAGTTGGCTATGGCGACGGGCCTTGCTAC
CCTGCGTCACATTCTGGAGCACCGACTGTGGGAGCATGCCCAGGTGATGGGCGAGCGACTCCTCACCCACCTGCACCAGA
TCCGCAGCAGTTGGATTGGCGAAGTGCGGGGGCGGGGGCTGATGCTTGGGGTCGAAATCGTCGACCCAACGGGTGAGCCC
GACTACCGGGGCATTGCCCCCCATGCAGGAGCGATGGCGCGAAGGATCCAGGCCGAGTGCCTGGAGCGCGGAGTCATCGT
CGAAGTGGGCGGGCGCGACGGCAGCGTCGTGCGCTTCCTGCCGCCGCTCATCGTCACCGACAGCCAGATAGACACAATAG
CCGAGGTATTCCACGATGCAGTCCATGCAGCCACCCGAATTACAAGCACCGCTCCAGACTCAAGAATCGCGCTGCCCACA
GCCGCCCTTTGA

Upstream 100 bases:

>100_bases
TACCATGCTCCTGAACAGTCCAGGTGGCCCGGTTTCGGCCCACTGCCTCTTCGGCCAGCCCGTAGACATCGCCCAGACCT
TCCGCGCGTTTGTTGAAGAC

Downstream 100 bases:

>100_bases
GCATCTGTTTCTATCTGGGGCTGAGGCGGGCACTGCTGCCTACCGGCAGGCAGTCTCGACTGCCACCGATATCCTCGTGC
GCTTCGCTCTCCAGCCGCAG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRRAAGDRPVAGPMRELLQGPGVENPPASSGPYLQRQAQRESNARSYPRRIPFAFKKAEGVYLTSVEGKQYIDCLAGAGA
LPLGHNHPVAIQAIQTVIRGKFPLLTLDLPTPLKDRFVDELFACLPAEFARNARIQFCSPAGTDAVEAALKLVKTATARR
GILSFQGAYHGMSHGSLSLTGNLAAKVVPNLMPEVQFLPYPYELRCPFGLGGEVGYRTGLHYIENLLKDPEGGVPSPAGI
ILEVVQGEGGVIPAPDEWLRGLRRITQEQQIPLIVDEIQTGFGRTGKLFAFEHSGIVPDVLLLSKAIGGGLPLAVVVYRE
SLDRWQPGAHAGTFRGNQLAMATGLATLRHILEHRLWEHAQVMGERLLTHLHQIRSSWIGEVRGRGLMLGVEIVDPTGEP
DYRGIAPHAGAMARRIQAECLERGVIVEVGGRDGSVVRFLPPLIVTDSQIDTIAEVFHDAVHAATRITSTAPDSRIALPT
AAL

Sequences:

>Translated_483_residues
MRRAAGDRPVAGPMRELLQGPGVENPPASSGPYLQRQAQRESNARSYPRRIPFAFKKAEGVYLTSVEGKQYIDCLAGAGA
LPLGHNHPVAIQAIQTVIRGKFPLLTLDLPTPLKDRFVDELFACLPAEFARNARIQFCSPAGTDAVEAALKLVKTATARR
GILSFQGAYHGMSHGSLSLTGNLAAKVVPNLMPEVQFLPYPYELRCPFGLGGEVGYRTGLHYIENLLKDPEGGVPSPAGI
ILEVVQGEGGVIPAPDEWLRGLRRITQEQQIPLIVDEIQTGFGRTGKLFAFEHSGIVPDVLLLSKAIGGGLPLAVVVYRE
SLDRWQPGAHAGTFRGNQLAMATGLATLRHILEHRLWEHAQVMGERLLTHLHQIRSSWIGEVRGRGLMLGVEIVDPTGEP
DYRGIAPHAGAMARRIQAECLERGVIVEVGGRDGSVVRFLPPLIVTDSQIDTIAEVFHDAVHAATRITSTAPDSRIALPT
AAL
>Mature_483_residues
MRRAAGDRPVAGPMRELLQGPGVENPPASSGPYLQRQAQRESNARSYPRRIPFAFKKAEGVYLTSVEGKQYIDCLAGAGA
LPLGHNHPVAIQAIQTVIRGKFPLLTLDLPTPLKDRFVDELFACLPAEFARNARIQFCSPAGTDAVEAALKLVKTATARR
GILSFQGAYHGMSHGSLSLTGNLAAKVVPNLMPEVQFLPYPYELRCPFGLGGEVGYRTGLHYIENLLKDPEGGVPSPAGI
ILEVVQGEGGVIPAPDEWLRGLRRITQEQQIPLIVDEIQTGFGRTGKLFAFEHSGIVPDVLLLSKAIGGGLPLAVVVYRE
SLDRWQPGAHAGTFRGNQLAMATGLATLRHILEHRLWEHAQVMGERLLTHLHQIRSSWIGEVRGRGLMLGVEIVDPTGEP
DYRGIAPHAGAMARRIQAECLERGVIVEVGGRDGSVVRFLPPLIVTDSQIDTIAEVFHDAVHAATRITSTAPDSRIALPT
AAL

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=432, Percent_Identity=27.5462962962963, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI4557809, Length=445, Percent_Identity=25.8426966292135, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI24119277, Length=425, Percent_Identity=25.6470588235294, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI37574042, Length=437, Percent_Identity=24.9427917620137, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI284507298, Length=323, Percent_Identity=26.9349845201238, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI226442705, Length=437, Percent_Identity=24.4851258581236, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI188536080, Length=443, Percent_Identity=24.3792325056433, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI38679950, Length=443, Percent_Identity=24.3792325056433, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI38679946, Length=443, Percent_Identity=24.3792325056433, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226442709, Length=406, Percent_Identity=24.8768472906404, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1787560, Length=417, Percent_Identity=35.9712230215827, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI145693181, Length=418, Percent_Identity=32.7751196172249, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1789016, Length=451, Percent_Identity=31.9290465631929, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=30.952380952381, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1788044, Length=431, Percent_Identity=31.0904872389791, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1786349, Length=322, Percent_Identity=32.2981366459627, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786991, Length=426, Percent_Identity=29.1079812206573, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564660, Length=427, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=26.1282660332542, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=428, Percent_Identity=24.2990654205607, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=252, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=23.7668161434978, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323470, Length=441, Percent_Identity=27.891156462585, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6321456, Length=449, Percent_Identity=23.8307349665924, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324386, Length=371, Percent_Identity=23.989218328841, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574759, Length=447, Percent_Identity=28.1879194630872, Blast_Score=152, Evalue=7e-37,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=28.0092592592593, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI21357415, Length=465, Percent_Identity=26.6666666666667, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21356575, Length=441, Percent_Identity=25.8503401360544, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=442, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667139, Length=442, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667143, Length=442, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 52262; Mature: 52262

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAAGDRPVAGPMRELLQGPGVENPPASSGPYLQRQAQRESNARSYPRRIPFAFKKAEG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCC
VYLTSVEGKQYIDCLAGAGALPLGHNHPVAIQAIQTVIRGKFPLLTLDLPTPLKDRFVDE
EEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
LFACLPAEFARNARIQFCSPAGTDAVEAALKLVKTATARRGILSFQGAYHGMSHGSLSLT
HHHHCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHCCCCCCCEEEE
GNLAAKVVPNLMPEVQFLPYPYELRCPFGLGGEVGYRTGLHYIENLLKDPEGGVPSPAGI
CCHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHH
ILEVVQGEGGVIPAPDEWLRGLRRITQEQQIPLIVDEIQTGFGRTGKLFAFEHSGIVPDV
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCEEEEECCCCCHHH
LLLSKAIGGGLPLAVVVYRESLDRWQPGAHAGTFRGNQLAMATGLATLRHILEHRLWEHA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVMGERLLTHLHQIRSSWIGEVRGRGLMLGVEIVDPTGEPDYRGIAPHAGAMARRIQAEC
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LERGVIVEVGGRDGSVVRFLPPLIVTDSQIDTIAEVFHDAVHAATRITSTAPDSRIALPT
HHCCCEEEECCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AAL
CCC
>Mature Secondary Structure
MRRAAGDRPVAGPMRELLQGPGVENPPASSGPYLQRQAQRESNARSYPRRIPFAFKKAEG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCC
VYLTSVEGKQYIDCLAGAGALPLGHNHPVAIQAIQTVIRGKFPLLTLDLPTPLKDRFVDE
EEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
LFACLPAEFARNARIQFCSPAGTDAVEAALKLVKTATARRGILSFQGAYHGMSHGSLSLT
HHHHCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCCHHCCCCCCCEEEE
GNLAAKVVPNLMPEVQFLPYPYELRCPFGLGGEVGYRTGLHYIENLLKDPEGGVPSPAGI
CCHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHH
ILEVVQGEGGVIPAPDEWLRGLRRITQEQQIPLIVDEIQTGFGRTGKLFAFEHSGIVPDV
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCEEEEECCCCCHHH
LLLSKAIGGGLPLAVVVYRESLDRWQPGAHAGTFRGNQLAMATGLATLRHILEHRLWEHA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVMGERLLTHLHQIRSSWIGEVRGRGLMLGVEIVDPTGEPDYRGIAPHAGAMARRIQAEC
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LERGVIVEVGGRDGSVVRFLPPLIVTDSQIDTIAEVFHDAVHAATRITSTAPDSRIALPT
HHCCCEEEECCCCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AAL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]