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The map label for this gene is rfbB [C]

Identifier: 37521748

GI number: 37521748

Start: 2329248

End: 2330207

Strand: Reverse

Name: rfbB [C]

Synonym: gvip303

Alternate gene names: 37521748

Gene position: 2330207-2329248 (Counterclockwise)

Preceding gene: 37521749

Following gene: 37521747

Centisome position: 50.01

GC content: 61.15

Gene sequence:

>960_bases
ATGCGCATACTGGTTACCGGCGGAGCGGGCTTCATCGGCTCGCACCTGTGTGAACGACTGGTTGGCGAAGGACACGAAGT
CCTCTGCCTGGACAATTTCTACACCGGCTCGCGGCTCAACATCGCCCCCTTACTCACCCACCCGCGTTTTGAGCTGATTC
GCCACGACGTCATCGAGCCGATTCTGCTCGAGGTCGAACGCATCTACCACCTGGCTTGCCCCGCCTCCCCGGTGCACTAC
CAGGCCAACCCGATCAAAACGATCAAGACCGGCGTGCTGGGCACCCTCAACATGCTGGGTCTGGCCAAGCGGGTCAGAGC
GCGCCTGTTGCTCGCTTCGACTTCGGAAGTTTACGGCGACCCGCTGGTGCACCCGCAGCACGAAGAGTACTGGGGACATG
TCAACCCGATTGGCGTGCGCAGCTGCTACGACGAATCGAAGCGCCTCGCCGAGACCTTGACGATGGACTACCACCGCCAG
AACGGAGTCGATACGCGGATTATCCGGATTTTTAACACCTACGGTCCGCGCATGAGCGAGCACGACGGGCGGGTGGTCAG
CAACCTCATTGTCCAGGCACTGCAGGGAGAAGCACTGAGCGTTTACGGCAACGGTGAGCAGACGCGCAGCTTCTGCTATG
TGTCGGACCTGGTGGAGGGGATGGTCGGGCTCATGGAAAGCGACTATACCCACCCGGTGAATCTTGGCAATCCGGGGGAG
TATACGATCAATGAGCTGGCAGACTTGGTGCGGAAGCTGATCAATCCGGGCTTGCCTATCGTGTACCGGCCCCTACCGTC
CGATGATCCGCGCCAGCGCCGACCGGACATCTCCCTGGCACGACGTTTGCTGGGATGGCAGCCCCAGGTTGAACTGCGCG
AAGGGCTCTTGCTGACGGCGGAGGACTTTGCCAAACGGCTGGGTAGAGGAGTGCGCCCGAGCTTGATTGCAGTGCCCTGA

Upstream 100 bases:

>100_bases
ATTGTCATCGACGCGCGCAACTGCCTGGACACCCAGGCGGTGCAGGGTGCCGGGCTGCGCTACGTCGGTGTCGGCCGCTA
ACAACTGAGGAGAACAACCC

Downstream 100 bases:

>100_bases
GGCCCGGACCTCGAGGGAAGCACTGCGGGGCGACCAATGGGACCGGTCCGGGCTGGCGCCCTTCATCCGCTCAGAAAGAC
CGCGTCCTGACCCCTACCCA

Product: dTDP-glucose 4-6-dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRILVTGGAGFIGSHLCERLVGEGHEVLCLDNFYTGSRLNIAPLLTHPRFELIRHDVIEPILLEVERIYHLACPASPVHY
QANPIKTIKTGVLGTLNMLGLAKRVRARLLLASTSEVYGDPLVHPQHEEYWGHVNPIGVRSCYDESKRLAETLTMDYHRQ
NGVDTRIIRIFNTYGPRMSEHDGRVVSNLIVQALQGEALSVYGNGEQTRSFCYVSDLVEGMVGLMESDYTHPVNLGNPGE
YTINELADLVRKLINPGLPIVYRPLPSDDPRQRRPDISLARRLLGWQPQVELREGLLLTAEDFAKRLGRGVRPSLIAVP

Sequences:

>Translated_319_residues
MRILVTGGAGFIGSHLCERLVGEGHEVLCLDNFYTGSRLNIAPLLTHPRFELIRHDVIEPILLEVERIYHLACPASPVHY
QANPIKTIKTGVLGTLNMLGLAKRVRARLLLASTSEVYGDPLVHPQHEEYWGHVNPIGVRSCYDESKRLAETLTMDYHRQ
NGVDTRIIRIFNTYGPRMSEHDGRVVSNLIVQALQGEALSVYGNGEQTRSFCYVSDLVEGMVGLMESDYTHPVNLGNPGE
YTINELADLVRKLINPGLPIVYRPLPSDDPRQRRPDISLARRLLGWQPQVELREGLLLTAEDFAKRLGRGVRPSLIAVP
>Mature_319_residues
MRILVTGGAGFIGSHLCERLVGEGHEVLCLDNFYTGSRLNIAPLLTHPRFELIRHDVIEPILLEVERIYHLACPASPVHY
QANPIKTIKTGVLGTLNMLGLAKRVRARLLLASTSEVYGDPLVHPQHEEYWGHVNPIGVRSCYDESKRLAETLTMDYHRQ
NGVDTRIIRIFNTYGPRMSEHDGRVVSNLIVQALQGEALSVYGNGEQTRSFCYVSDLVEGMVGLMESDYTHPVNLGNPGE
YTINELADLVRKLINPGLPIVYRPLPSDDPRQRRPDISLARRLLGWQPQVELREGLLLTAEDFAKRLGRGVRPSLIAVP

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=306, Percent_Identity=61.437908496732, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI7657641, Length=340, Percent_Identity=26.1764705882353, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788589, Length=350, Percent_Identity=28.2857142857143, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=28.0597014925373, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788353, Length=335, Percent_Identity=28.3582089552239, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786974, Length=326, Percent_Identity=28.8343558282209, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=57.8274760383387, Blast_Score=389, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71982035, Length=333, Percent_Identity=27.027027027027, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982038, Length=335, Percent_Identity=26.865671641791, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=27.1084337349398, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319493, Length=331, Percent_Identity=24.1691842900302, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=59.1639871382637, Blast_Score=397, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35739; Mature: 35739

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGFIGSHLCERLVGEGHEVLCLDNFYTGSRLNIAPLLTHPRFELIRHDVIEP
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
ILLEVERIYHLACPASPVHYQANPIKTIKTGVLGTLNMLGLAKRVRARLLLASTSEVYGD
HHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
PLVHPQHEEYWGHVNPIGVRSCYDESKRLAETLTMDYHRQNGVDTRIIRIFNTYGPRMSE
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHCCCCCCC
HDGRVVSNLIVQALQGEALSVYGNGEQTRSFCYVSDLVEGMVGLMESDYTHPVNLGNPGE
CCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YTINELADLVRKLINPGLPIVYRPLPSDDPRQRRPDISLARRLLGWQPQVELREGLLLTA
CCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCHHHHHHHHCCCCCHHHHCCEEEEH
EDFAKRLGRGVRPSLIAVP
HHHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MRILVTGGAGFIGSHLCERLVGEGHEVLCLDNFYTGSRLNIAPLLTHPRFELIRHDVIEP
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHH
ILLEVERIYHLACPASPVHYQANPIKTIKTGVLGTLNMLGLAKRVRARLLLASTSEVYGD
HHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
PLVHPQHEEYWGHVNPIGVRSCYDESKRLAETLTMDYHRQNGVDTRIIRIFNTYGPRMSE
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHCCCCCCC
HDGRVVSNLIVQALQGEALSVYGNGEQTRSFCYVSDLVEGMVGLMESDYTHPVNLGNPGE
CCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YTINELADLVRKLINPGLPIVYRPLPSDDPRQRRPDISLARRLLGWQPQVELREGLLLTA
CCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHCCCCHHHHHHHHCCCCCHHHHCCEEEEH
EDFAKRLGRGVRPSLIAVP
HHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]