Click here to switch to the map view.

The map label for this gene is ahpC [C]

Identifier: 37521724

GI number: 37521724

Start: 2306020

End: 2306658

Strand: Direct

Name: ahpC [C]

Synonym: glr2155

Alternate gene names: 37521724

Gene position: 2306020-2306658 (Clockwise)

Preceding gene: 37521722

Following gene: 37521725

Centisome position: 49.5

GC content: 59.62

Gene sequence:

>639_bases
ATGGCCCTTCGATTAGGTGACAAGGTACCGGACTTCACCCAGGAGTCCACCGAAGGCCCGATCCAGTTCTACGATTGGGC
AGGGGACAGTTGGGTGGTCCTTTTTTCTCATCCAAAAGATTTCACGCCCGTGTGCACCACCGAACTCGGTGAGGTAGCCA
AGCTCAAGCCCGAATTCGCCAAACGCAACGTCAAGGTGATTGCCCTGAGCGTCGACGATGTCGATTCCCACAAAGGCTGG
GCTCAGGACATCGAGGAGACCCAGGGGGCGGCCTTGAATTTTCCGGTGCTCGCCGACGCCGATCGCAAGGTGAGCGACCT
CTACGACATGATCCACCCCAGCGCCAACGACACCCTGACGGTGCGCTCGGTGTTCGTGATCGATCCCAACCAGAAACTGC
GCCTGACGCTCACCTATCCGGCAAGCACCGGCCGCAACTTCGACGAACTGCTGCGGGTGATCGACTCGCTGCAACTGACC
GACAACTACTCGGTGGCCACCCCGGCCAACTGGCAGGACGGCGAGGACTGTGTGATCGTTCCGTCGCTCAAAGACGAAGC
AGTGCTCAAGGAGAAGTTCCCCAAGGGCTACACCGTCGTCAAGCCCTACCTGCGCATGACCCCGCAGCCGAATAAGTAG

Upstream 100 bases:

>100_bases
GTAAATAGTGCAGCGATATAGTCGTATCCCGCCGGGAGTACCGGTGTTTTATGCTACAGTGTAGGCCGTCATTGCATGCA
TCATAAGAGGAAGCGCAGAC

Downstream 100 bases:

>100_bases
ACCCCCGTGACCTGCAGGCGATGGGGCAGACGGCATCCGTCTGCCCCATTGTTTTAGATTGCAACGACGAGGCTGAGTAA
TCAGAGCGCCAAACGCAAGG

Product: AhpC/TSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MALRLGDKVPDFTQESTEGPIQFYDWAGDSWVVLFSHPKDFTPVCTTELGEVAKLKPEFAKRNVKVIALSVDDVDSHKGW
AQDIEETQGAALNFPVLADADRKVSDLYDMIHPSANDTLTVRSVFVIDPNQKLRLTLTYPASTGRNFDELLRVIDSLQLT
DNYSVATPANWQDGEDCVIVPSLKDEAVLKEKFPKGYTVVKPYLRMTPQPNK

Sequences:

>Translated_212_residues
MALRLGDKVPDFTQESTEGPIQFYDWAGDSWVVLFSHPKDFTPVCTTELGEVAKLKPEFAKRNVKVIALSVDDVDSHKGW
AQDIEETQGAALNFPVLADADRKVSDLYDMIHPSANDTLTVRSVFVIDPNQKLRLTLTYPASTGRNFDELLRVIDSLQLT
DNYSVATPANWQDGEDCVIVPSLKDEAVLKEKFPKGYTVVKPYLRMTPQPNK
>Mature_211_residues
ALRLGDKVPDFTQESTEGPIQFYDWAGDSWVVLFSHPKDFTPVCTTELGEVAKLKPEFAKRNVKVIALSVDDVDSHKGWA
QDIEETQGAALNFPVLADADRKVSDLYDMIHPSANDTLTVRSVFVIDPNQKLRLTLTYPASTGRNFDELLRVIDSLQLTD
NYSVATPANWQDGEDCVIVPSLKDEAVLKEKFPKGYTVVKPYLRMTPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=222, Percent_Identity=50.4504504504504, Blast_Score=219, Evalue=1e-57,
Organism=Homo sapiens, GI32189392, Length=197, Percent_Identity=32.994923857868, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=30.5555555555556, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI5453549, Length=160, Percent_Identity=31.25, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI32483377, Length=142, Percent_Identity=31.6901408450704, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI5802974, Length=142, Percent_Identity=31.6901408450704, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786822, Length=183, Percent_Identity=30.6010928961749, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25153706, Length=199, Percent_Identity=43.7185929648241, Blast_Score=176, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI193204376, Length=196, Percent_Identity=33.6734693877551, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32565831, Length=186, Percent_Identity=33.8709677419355, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17554494, Length=150, Percent_Identity=32.6666666666667, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319407, Length=213, Percent_Identity=53.9906103286385, Blast_Score=220, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323613, Length=157, Percent_Identity=30.5732484076433, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=53.4246575342466, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24652434, Length=203, Percent_Identity=49.2610837438424, Blast_Score=198, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17975518, Length=203, Percent_Identity=49.2610837438424, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24652436, Length=203, Percent_Identity=49.2610837438424, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=33.125, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=33.125, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=32.5714285714286, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357347, Length=166, Percent_Identity=30.1204819277108, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=150, Percent_Identity=32.6666666666667, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864676, Length=150, Percent_Identity=32.6666666666667, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23760; Mature: 23629

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRLGDKVPDFTQESTEGPIQFYDWAGDSWVVLFSHPKDFTPVCTTELGEVAKLKPEFA
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHH
KRNVKVIALSVDDVDSHKGWAQDIEETQGAALNFPVLADADRKVSDLYDMIHPSANDTLT
HCCEEEEEEEECCCCCCCCHHHHHHHHCCCEECCCEEECCCCHHHHHHHHHCCCCCCEEE
VRSVFVIDPNQKLRLTLTYPASTGRNFDELLRVIDSLQLTDNYSVATPANWQDGEDCVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCEEEE
PSLKDEAVLKEKFPKGYTVVKPYLRMTPQPNK
ECCCCHHHHHHHCCCCCEEEEHHHHCCCCCCC
>Mature Secondary Structure 
ALRLGDKVPDFTQESTEGPIQFYDWAGDSWVVLFSHPKDFTPVCTTELGEVAKLKPEFA
CCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHH
KRNVKVIALSVDDVDSHKGWAQDIEETQGAALNFPVLADADRKVSDLYDMIHPSANDTLT
HCCEEEEEEEECCCCCCCCHHHHHHHHCCCEECCCEEECCCCHHHHHHHHHCCCCCCEEE
VRSVFVIDPNQKLRLTLTYPASTGRNFDELLRVIDSLQLTDNYSVATPANWQDGEDCVIV
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCEEEE
PSLKDEAVLKEKFPKGYTVVKPYLRMTPQPNK
ECCCCHHHHHHHCCCCCEEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]