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The map label for this gene is prmA

Identifier: 37521705

GI number: 37521705

Start: 2287095

End: 2288045

Strand: Direct

Name: prmA

Synonym: glr2136

Alternate gene names: 37521705

Gene position: 2287095-2288045 (Clockwise)

Preceding gene: 37521703

Following gene: 37521707

Centisome position: 49.09

GC content: 68.03

Gene sequence:

>951_bases
GTGTACCCTGCTATAACGCCATTGCAAGCGGGGCTACAGTGGTGGGCGGTGGCCGGGAGGCAGGGTGTGGCCGAGCTATG
GCAAGTGCAGGTGGAGACGGCCGCGGACGGGGCCGACGGCGAGGTCGAAGAGACGCTCTACTGGTATCTGAGCGAACTGG
GGCTTCCCCACGTCGAGCGGCAAATTCTCGCAGGGCGGCTGGTGCTGCGGGGGTATCTGAGCGGCGAGACGCCCGAGGGG
GTGATGGAGCGCTGGCGCGAACACATCCGAGAGCGGCTGACCCAAAAGGCAGAAATTGGCTGGTACGCAGTGGAGCGGCG
CGACTGGCAGGCGGCCTGGCGCGAGCAGTGGCGGCCGATATTCGTGGGCGAACGCCTGGTTATCTGGCCGGTGTGGTTGC
CGGATCCCCCCGGCGACCGGCTGGTGATCCCCCTCGATCCGGGCATGGCCTTCGGCACCGGCGAGCACGCCACCACCCGG
CTGTGCCTGCGGGCACTCGAATCCGTACCGGATCTGGGCACTTTTGCCGATGTCGGCTGCGGCTCCGGAGTGCTCACGGT
GGCGGCCCTCAAGTTGGGGGCCGGGCGAGGCTGGGCGGTTGACACCGACGATCTGGCCGTCGTCTCCACCCGCAAGAATC
TCGAAATCAGCGGGCTGGAGGAGCGGGTCACCGTCGCGCGCGGCAGCACCGAGCAGTTGTCCGGACCGCTCGATGGGGTG
GTGAGCAACATCCTGGCCGAGGTGATCGCCAATCTGGCCCCGGAATTTCGGCGGCTGGTGCACCCCGGCGGCTGGGGCAT
CTTCAGCGGCCTGCTGCTTACCCAGGCTCCCCGCGTGGTCGAAGCCCTTGCCGGACAAGGTTTTGCACTTTCCGAGACCC
TCAGTGAAGGCGACTGGGCCTGCCTGGTGGGCCGCTTCAGCGCGGATCGCCCCCGAAGCGCCGGTAGCTGA

Upstream 100 bases:

>100_bases
CGGTGAAAAGTTGCCCATGCAGTCATCACTTTCAATCATACTTTGAAATGCTTAACAGAGGAGCCTCCCGACGGCCGGGC
GGCGGAGCGCTATTTGTGAA

Downstream 100 bases:

>100_bases
AGGCCGAGAGCAAAGGATCTTCGTCGCCGGTGAGCGCGCGGGTCACCAGCTGGGCGGTGACCGGTGCGAGCAGAACCCCG
TTGCGATGGTGACCGGTCGC

Product: methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYPAITPLQAGLQWWAVAGRQGVAELWQVQVETAADGADGEVEETLYWYLSELGLPHVERQILAGRLVLRGYLSGETPEG
VMERWREHIRERLTQKAEIGWYAVERRDWQAAWREQWRPIFVGERLVIWPVWLPDPPGDRLVIPLDPGMAFGTGEHATTR
LCLRALESVPDLGTFADVGCGSGVLTVAALKLGAGRGWAVDTDDLAVVSTRKNLEISGLEERVTVARGSTEQLSGPLDGV
VSNILAEVIANLAPEFRRLVHPGGWGIFSGLLLTQAPRVVEALAGQGFALSETLSEGDWACLVGRFSADRPRSAGS

Sequences:

>Translated_316_residues
MYPAITPLQAGLQWWAVAGRQGVAELWQVQVETAADGADGEVEETLYWYLSELGLPHVERQILAGRLVLRGYLSGETPEG
VMERWREHIRERLTQKAEIGWYAVERRDWQAAWREQWRPIFVGERLVIWPVWLPDPPGDRLVIPLDPGMAFGTGEHATTR
LCLRALESVPDLGTFADVGCGSGVLTVAALKLGAGRGWAVDTDDLAVVSTRKNLEISGLEERVTVARGSTEQLSGPLDGV
VSNILAEVIANLAPEFRRLVHPGGWGIFSGLLLTQAPRVVEALAGQGFALSETLSEGDWACLVGRFSADRPRSAGS
>Mature_316_residues
MYPAITPLQAGLQWWAVAGRQGVAELWQVQVETAADGADGEVEETLYWYLSELGLPHVERQILAGRLVLRGYLSGETPEG
VMERWREHIRERLTQKAEIGWYAVERRDWQAAWREQWRPIFVGERLVIWPVWLPDPPGDRLVIPLDPGMAFGTGEHATTR
LCLRALESVPDLGTFADVGCGSGVLTVAALKLGAGRGWAVDTDDLAVVSTRKNLEISGLEERVTVARGSTEQLSGPLDGV
VSNILAEVIANLAPEFRRLVHPGGWGIFSGLLLTQAPRVVEALAGQGFALSETLSEGDWACLVGRFSADRPRSAGS

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=203, Percent_Identity=40.3940886699507, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_GLOVI (Q7NIP7)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925082.1
- ProteinModelPortal:   Q7NIP7
- GeneID:   2600537
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr2136
- NMPDR:   fig|251221.1.peg.2136
- HOGENOM:   HBG584653
- OMA:   AIDIDDW
- BioCyc:   GVIO251221:GLR2136-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34540; Mature: 34540

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPAITPLQAGLQWWAVAGRQGVAELWQVQVETAADGADGEVEETLYWYLSELGLPHVER
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHH
QILAGRLVLRGYLSGETPEGVMERWREHIRERLTQKAEIGWYAVERRDWQAAWREQWRPI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCEE
FVGERLVIWPVWLPDPPGDRLVIPLDPGMAFGTGEHATTRLCLRALESVPDLGTFADVGC
EECCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC
GSGVLTVAALKLGAGRGWAVDTDDLAVVSTRKNLEISGLEERVTVARGSTEQLSGPLDGV
CCHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCEECCHHHHHHHHCCCHHHHCCCHHHH
VSNILAEVIANLAPEFRRLVHPGGWGIFSGLLLTQAPRVVEALAGQGFALSETLSEGDWA
HHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCEEHHHHCCCCEE
CLVGRFSADRPRSAGS
EEEECCCCCCCCCCCC
>Mature Secondary Structure
MYPAITPLQAGLQWWAVAGRQGVAELWQVQVETAADGADGEVEETLYWYLSELGLPHVER
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHH
QILAGRLVLRGYLSGETPEGVMERWREHIRERLTQKAEIGWYAVERRDWQAAWREQWRPI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCCCEE
FVGERLVIWPVWLPDPPGDRLVIPLDPGMAFGTGEHATTRLCLRALESVPDLGTFADVGC
EECCEEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCC
GSGVLTVAALKLGAGRGWAVDTDDLAVVSTRKNLEISGLEERVTVARGSTEQLSGPLDGV
CCHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCEECCHHHHHHHHCCCHHHHCCCHHHH
VSNILAEVIANLAPEFRRLVHPGGWGIFSGLLLTQAPRVVEALAGQGFALSETLSEGDWA
HHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCCCCEEHHHHCCCCEE
CLVGRFSADRPRSAGS
EEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292