Click here to switch to the map view.

The map label for this gene is btuB [H]

Identifier: 37521685

GI number: 37521685

Start: 2269343

End: 2271400

Strand: Direct

Name: btuB [H]

Synonym: glr2116

Alternate gene names: 37521685

Gene position: 2269343-2271400 (Clockwise)

Preceding gene: 37521683

Following gene: 37521687

Centisome position: 48.71

GC content: 62.97

Gene sequence:

>2058_bases
ATGAGATCCCACACCCTCCATTGCGCCTTCGCCTGGACCCTGGCGCTGTGCCTGCCCGTGTCCTGCCTGGCGGAGACAGT
GATCACCCGCGCCGATCTGAACTTCCCCTTGTACTCGGCCCGCGACCTGGTAGCTCCCGCCCTTGCCCAAGCGCCACCCA
GACAAGCCGATTCCCCACCGGTAGAAGTGCCACCGGTGCTTTCACCCCAGGTGGAGACTTTGCAGCCGCTGCCGCCGGTG
GCGCCGGTCTACACAGTCCCCGCCGCCCAGATCGAAAAGCAGGGCTCCCAGAGCCTGGCAGATGTGTTGCGCGGCATGCC
GGGCTTTGCCGTCAACGACGTGGGACCGGCGGCGGATATTCACACCGGCACCTACTACCGGGGATCTTCGATCAACCAGT
CGACGTTTTTGCTCAACGGTCGTCCCTACGGCTCCAACATCAGCACCTACCACGGCGCCACCGACTTAAACGCCCTGCCG
GTCGAATCGATCGAAAAAGTAGAGCTTTCCAGCGGCGCCAGTTCGACACTCTACGGCACCGAGGGCTTCGGCGGCGTGGT
GAACGTGATCACCAAAAAGGGCAAAGGCCCGCCCCAATTCAAAGCGGGGGCCGAGTGGGGCAATTACTCCCAGGCAAACT
ACCAGGCGAGTTTCTCCGGGTCCACCGAGCAGTTGAGCTACCGGGTGGGCTATCAGAGTTTTTTGACCGACAACCGCTAC
TACGTGCCGGAAGCATCGATCAATCGCGGCGCGGACGGGTTGCTTTTCAACGGCGACACCTACCGCAACAGCTACTCGGG
CAACTTTACCTTTGACATCGACCCGCGCAATGCCATCAGCCTCGATGTCACCAAGATCCTCTCGCGACGCGGATTGTTGT
ACTTTGGCTTTCCCGGCAGCTGCAGTCCGACCCTGGCGCTGCAGTGCGACCGCCTCGACCACGACGGGTTCAACCTGGGC
CTGGGATCGCGCCATCAGCTTGGGGCGGGCGAGGATTCGGTGCTCACGGTCAACCTCGGCTACAACCAGGACTACTTCAA
CACCTACGGCCCCACCGGCGTGCGCTTCAACCGCACCGGCACCCTCGACACCAACTTGCTGAGCGCCCGCGTCGAACACG
ACTGGAAGACCGCCCCCAATCTGCAGTTGCGCTACGGCCTCGATGCCACCAGCAACCAACTCAATAGCGACACGCTCAGC
ACGCTGCCCAATCGGGCGCCCTTCAATGAAGTGGAGAACCGGGCCGTCTTCAACGGCGCCCTGTTTGCCGTGGGAAGCTG
GAGCGTGGCCCCCTCGGCGGTGCTGGAACTGGGCGTGCGCCAGACCGTCAACAGCCGCTTCAACAGTTACACCAACCCGA
GCGCCGGCTTTCGCTGGGCGCTCAGCCCCGATGTCGCCCTGCGCGCAAGCTGGGTGCTCGCCCAGCGCAACCCCGGTCTC
GATCAGCTCTACGTCTACGATACGGTGCACGGCTGGCTGCCCAACGATCAATTGGTGCCTGAGACCGGTTCGGCCTACAC
CGCCGGCCTCGACGTGCGTTTCAGCGACGCGCTCGAAGGCAAATTCACCTACTTCGGCAGCGGCCTGAATAATCGCCTTG
CCGTCGTGACCGGCCAGTGGCAGAACGTCGGGGTAGTGGCCACCAATGGCCTGGAGGCGGCGGTGCGCTGGCAGATGGCA
CCGCAGTGGTCGAGTTTTCTCAACTACACCTACACCGACGCGCGCATTCTCACCGGCCCGGAATCGGGACTGCAATTGGG
CTTTGTACCCTACTCGGTCGGGCAGGCCGGGGTAGGCTACGACAACAGCGGCTGGCAGGCCAATGTGCAGGTTACCTACG
GCAGCGGCTCGCGCCGGGCATTTTTTAATTTCGACAGCACCAATACCGATTTCTCGCCCCCCTGGGCCTCGCTCGATCTC
AGAGCCCGCATCCCGATCAACCCAAACCTGGCGATTACCGCCTACGTCGAGAACCTGCTCGACATCCCCTACGAGCGGGT
CAACCGCACCTACACTCCCGGGCTGCTCTACCGGATCGGGTTGCAGACGAGTTTCTAG

Upstream 100 bases:

>100_bases
TATCACCCCGGCTGCTTTGGGCGTAAGTCTGACGGGCTGTCTTTTGACAGACCCCCGCGCGTTGCCGGAGCATGAGCAGG
CGTTATCGCCAAACCTTTTG

Downstream 100 bases:

>100_bases
CCGGACCATGCCGCAAATACGGTTTGCTGATAGGATTGCAGTAATTTCGCTTTGATCCCCACGGCCAGGCTTCCTTTCGC
GCCCTGTCGTCAGTTACTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MRSHTLHCAFAWTLALCLPVSCLAETVITRADLNFPLYSARDLVAPALAQAPPRQADSPPVEVPPVLSPQVETLQPLPPV
APVYTVPAAQIEKQGSQSLADVLRGMPGFAVNDVGPAADIHTGTYYRGSSINQSTFLLNGRPYGSNISTYHGATDLNALP
VESIEKVELSSGASSTLYGTEGFGGVVNVITKKGKGPPQFKAGAEWGNYSQANYQASFSGSTEQLSYRVGYQSFLTDNRY
YVPEASINRGADGLLFNGDTYRNSYSGNFTFDIDPRNAISLDVTKILSRRGLLYFGFPGSCSPTLALQCDRLDHDGFNLG
LGSRHQLGAGEDSVLTVNLGYNQDYFNTYGPTGVRFNRTGTLDTNLLSARVEHDWKTAPNLQLRYGLDATSNQLNSDTLS
TLPNRAPFNEVENRAVFNGALFAVGSWSVAPSAVLELGVRQTVNSRFNSYTNPSAGFRWALSPDVALRASWVLAQRNPGL
DQLYVYDTVHGWLPNDQLVPETGSAYTAGLDVRFSDALEGKFTYFGSGLNNRLAVVTGQWQNVGVVATNGLEAAVRWQMA
PQWSSFLNYTYTDARILTGPESGLQLGFVPYSVGQAGVGYDNSGWQANVQVTYGSGSRRAFFNFDSTNTDFSPPWASLDL
RARIPINPNLAITAYVENLLDIPYERVNRTYTPGLLYRIGLQTSF

Sequences:

>Translated_685_residues
MRSHTLHCAFAWTLALCLPVSCLAETVITRADLNFPLYSARDLVAPALAQAPPRQADSPPVEVPPVLSPQVETLQPLPPV
APVYTVPAAQIEKQGSQSLADVLRGMPGFAVNDVGPAADIHTGTYYRGSSINQSTFLLNGRPYGSNISTYHGATDLNALP
VESIEKVELSSGASSTLYGTEGFGGVVNVITKKGKGPPQFKAGAEWGNYSQANYQASFSGSTEQLSYRVGYQSFLTDNRY
YVPEASINRGADGLLFNGDTYRNSYSGNFTFDIDPRNAISLDVTKILSRRGLLYFGFPGSCSPTLALQCDRLDHDGFNLG
LGSRHQLGAGEDSVLTVNLGYNQDYFNTYGPTGVRFNRTGTLDTNLLSARVEHDWKTAPNLQLRYGLDATSNQLNSDTLS
TLPNRAPFNEVENRAVFNGALFAVGSWSVAPSAVLELGVRQTVNSRFNSYTNPSAGFRWALSPDVALRASWVLAQRNPGL
DQLYVYDTVHGWLPNDQLVPETGSAYTAGLDVRFSDALEGKFTYFGSGLNNRLAVVTGQWQNVGVVATNGLEAAVRWQMA
PQWSSFLNYTYTDARILTGPESGLQLGFVPYSVGQAGVGYDNSGWQANVQVTYGSGSRRAFFNFDSTNTDFSPPWASLDL
RARIPINPNLAITAYVENLLDIPYERVNRTYTPGLLYRIGLQTSF
>Mature_685_residues
MRSHTLHCAFAWTLALCLPVSCLAETVITRADLNFPLYSARDLVAPALAQAPPRQADSPPVEVPPVLSPQVETLQPLPPV
APVYTVPAAQIEKQGSQSLADVLRGMPGFAVNDVGPAADIHTGTYYRGSSINQSTFLLNGRPYGSNISTYHGATDLNALP
VESIEKVELSSGASSTLYGTEGFGGVVNVITKKGKGPPQFKAGAEWGNYSQANYQASFSGSTEQLSYRVGYQSFLTDNRY
YVPEASINRGADGLLFNGDTYRNSYSGNFTFDIDPRNAISLDVTKILSRRGLLYFGFPGSCSPTLALQCDRLDHDGFNLG
LGSRHQLGAGEDSVLTVNLGYNQDYFNTYGPTGVRFNRTGTLDTNLLSARVEHDWKTAPNLQLRYGLDATSNQLNSDTLS
TLPNRAPFNEVENRAVFNGALFAVGSWSVAPSAVLELGVRQTVNSRFNSYTNPSAGFRWALSPDVALRASWVLAQRNPGL
DQLYVYDTVHGWLPNDQLVPETGSAYTAGLDVRFSDALEGKFTYFGSGLNNRLAVVTGQWQNVGVVATNGLEAAVRWQMA
PQWSSFLNYTYTDARILTGPESGLQLGFVPYSVGQAGVGYDNSGWQANVQVTYGSGSRRAFFNFDSTNTDFSPPWASLDL
RARIPINPNLAITAYVENLLDIPYERVNRTYTPGLLYRIGLQTSF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=153, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790405, Length=647, Percent_Identity=23.8021638330757, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74539; Mature: 74539

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHTLHCAFAWTLALCLPVSCLAETVITRADLNFPLYSARDLVAPALAQAPPRQADSPP
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
VEVPPVLSPQVETLQPLPPVAPVYTVPAAQIEKQGSQSLADVLRGMPGFAVNDVGPAADI
CCCCCCCCCCHHHCCCCCCCCCEEECCHHHHHHCCHHHHHHHHHCCCCCEECCCCCCCCC
HTGTYYRGSSINQSTFLLNGRPYGSNISTYHGATDLNALPVESIEKVELSSGASSTLYGT
CCCCEEECCCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCHHHHEEECCCCCCEEECC
EGFGGVVNVITKKGKGPPQFKAGAEWGNYSQANYQASFSGSTEQLSYRVGYQSFLTDNRY
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHEEEEECHHHHHCCCEE
YVPEASINRGADGLLFNGDTYRNSYSGNFTFDIDPRNAISLDVTKILSRRGLLYFGFPGS
ECCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCEEEEECCCC
CSPTLALQCDRLDHDGFNLGLGSRHQLGAGEDSVLTVNLGYNQDYFNTYGPTGVRFNRTG
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCC
TLDTNLLSARVEHDWKTAPNLQLRYGLDATSNQLNSDTLSTLPNRAPFNEVENRAVFNGA
CCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCHHHHHCCEEECCE
LFAVGSWSVAPSAVLELGVRQTVNSRFNSYTNPSAGFRWALSPDVALRASWVLAQRNPGL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCC
DQLYVYDTVHGWLPNDQLVPETGSAYTAGLDVRFSDALEGKFTYFGSGLNNRLAVVTGQW
CEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEECC
QNVGVVATNGLEAAVRWQMAPQWSSFLNYTYTDARILTGPESGLQLGFVPYSVGQAGVGY
CCEEEEEECCCCEEEEEEECCCHHHHHCEEECCCEEEECCCCCCEEEEEEEECCCCCCCC
DNSGWQANVQVTYGSGSRRAFFNFDSTNTDFSPPWASLDLRARIPINPNLAITAYVENLL
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHH
DIPYERVNRTYTPGLLYRIGLQTSF
HCCHHHHCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRSHTLHCAFAWTLALCLPVSCLAETVITRADLNFPLYSARDLVAPALAQAPPRQADSPP
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
VEVPPVLSPQVETLQPLPPVAPVYTVPAAQIEKQGSQSLADVLRGMPGFAVNDVGPAADI
CCCCCCCCCCHHHCCCCCCCCCEEECCHHHHHHCCHHHHHHHHHCCCCCEECCCCCCCCC
HTGTYYRGSSINQSTFLLNGRPYGSNISTYHGATDLNALPVESIEKVELSSGASSTLYGT
CCCCEEECCCCCCCEEEEECCCCCCCCCEECCCCCCCCCCCCHHHHEEECCCCCCEEECC
EGFGGVVNVITKKGKGPPQFKAGAEWGNYSQANYQASFSGSTEQLSYRVGYQSFLTDNRY
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHEEEEECHHHHHCCCEE
YVPEASINRGADGLLFNGDTYRNSYSGNFTFDIDPRNAISLDVTKILSRRGLLYFGFPGS
ECCCCCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCEEEEECCCC
CSPTLALQCDRLDHDGFNLGLGSRHQLGAGEDSVLTVNLGYNQDYFNTYGPTGVRFNRTG
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCC
TLDTNLLSARVEHDWKTAPNLQLRYGLDATSNQLNSDTLSTLPNRAPFNEVENRAVFNGA
CCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHCCCCCCHHHHHCCEEECCE
LFAVGSWSVAPSAVLELGVRQTVNSRFNSYTNPSAGFRWALSPDVALRASWVLAQRNPGL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCC
DQLYVYDTVHGWLPNDQLVPETGSAYTAGLDVRFSDALEGKFTYFGSGLNNRLAVVTGQW
CEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEECC
QNVGVVATNGLEAAVRWQMAPQWSSFLNYTYTDARILTGPESGLQLGFVPYSVGQAGVGY
CCEEEEEECCCCEEEEEEECCCHHHHHCEEECCCEEEECCCCCCEEEEEEEECCCCCCCC
DNSGWQANVQVTYGSGSRRAFFNFDSTNTDFSPPWASLDLRARIPINPNLAITAYVENLL
CCCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHH
DIPYERVNRTYTPGLLYRIGLQTSF
HCCHHHHCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA