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The map label for this gene is degP [H]

Identifier: 37521666

GI number: 37521666

Start: 2249700

End: 2250902

Strand: Reverse

Name: degP [H]

Synonym: gll2097

Alternate gene names: 37521666

Gene position: 2250902-2249700 (Counterclockwise)

Preceding gene: 37521667

Following gene: 37521665

Centisome position: 48.31

GC content: 66.33

Gene sequence:

>1203_bases
GTGAAGACGTTCAAATCGGCTGAAGTGCTGATTATCGCCCTGCTGGCCGCTACCGGCGGCGCCGCCGGCAGCTATTTTGC
GGTGAGCCGGGTGTCGGCCCCTGCCGCGCCCTCCACCCCAGCTGCCGCTCCCCGGCCTGCCAACGCCCCCGCCAACTCCG
AGGCGCCGCTGCCGCCGCTGCCCACTTCCCTGGGCTCCGATGAACTCGACAACATCGCCGTCTACGAGCGGGTGAGCCCG
GCGGTGGTCAACATCACCACCACCGTGCTGCGCTACGACTACTTCAGCCGCGCCGTGCCCGAGCAGGGCAGCGGCTCCGG
GAGCATTCTCGATGCCCAGGGCCGCATCCTCACCAATTACCACGTGGTCCGCTCCCCCAAAAGCCGCCTGGAAGTCACCC
TCGCCAACGGCAAGCGCTACCGGGCGCGCCTAGTGGGGGCCGACCCGAGCAACGACCTGGCGGTGATTCAGTTGGAAGAT
CCGCCCCCCAACCTCACCACCATCACCCTGGGCGAATCGAGCAACCTGCAGGTGGGGCGCAAGGTGCTGGCGATCGGCAA
TCCCTTCGGCCTGGAGCGCACCCTTACCACCGGTGTGATCAGCGCCCTTGAGCGCGATCTGGCTTCCGAACGGGCAGGCC
GCACCCTCAGAAACCTCATCCAGACCGACGCCGCCATCAACCCGGGCAACTCCGGCGGGCCGTTGCTCGACAGCCAGGGT
CGGTTGATCGGGGTGAATACTGCAATATTCAGCACCAGCGGTTCGAGTGCGGGTATCGGCTTTGCCGTCCCGGTCGACAC
CGTGCGTCAAGTGCTGCCTGAATTGATCTCGCGCGGCACCGTCCGGCGCGCCTCCCTCGGCGTGCAGGTGCTGCCCCTTT
CGCCGATGGTGGTCGAAACGCTCAAATTGTCCGTCAAAGAAGGAGCGCTGGTGGCGGCGGTGGTTCCGGGAGGGGCTGCG
GCCCGCGCCGGACTGCGCGCCGGTCGGCTCGAGACGATCGACGGCAACCTGCAACTGCCGGTGGGGGCCGATGTGATCGT
GGCGATCGACAGAGTCGCCATCAAAGACGCCCAGGATCTGATCAACCAGATCCAGAAACACAAGCCGGGCGACAAGGTCA
CCCTCACGATCGTCCGCAACAACGCCGAAGTGCAGGTGCCCGTCACCCTGGGCGAACTGCGCGAGCAGCTCGAAGAACAA
TAA

Upstream 100 bases:

>100_bases
GCCCTGATCGAGATGCCCGAGGCCACCGTTGTCGTTCCGCTGGGATGGCAGGGAGTCATCGATCAATGCGGTACGCTGAT
ATTAGAATTCCAGACCGCCC

Downstream 100 bases:

>100_bases
GATACCAAGTTTCAGCGGCCGTACCCTGACACCTGGACACCCTTAAATCAGCGACCCCGAACGGGCTCGAACCGTCAACC
TCCGCCGTGACAGGGCGGCG

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKTFKSAEVLIIALLAATGGAAGSYFAVSRVSAPAAPSTPAAAPRPANAPANSEAPLPPLPTSLGSDELDNIAVYERVSP
AVVNITTTVLRYDYFSRAVPEQGSGSGSILDAQGRILTNYHVVRSPKSRLEVTLANGKRYRARLVGADPSNDLAVIQLED
PPPNLTTITLGESSNLQVGRKVLAIGNPFGLERTLTTGVISALERDLASERAGRTLRNLIQTDAAINPGNSGGPLLDSQG
RLIGVNTAIFSTSGSSAGIGFAVPVDTVRQVLPELISRGTVRRASLGVQVLPLSPMVVETLKLSVKEGALVAAVVPGGAA
ARAGLRAGRLETIDGNLQLPVGADVIVAIDRVAIKDAQDLINQIQKHKPGDKVTLTIVRNNAEVQVPVTLGELREQLEEQ

Sequences:

>Translated_400_residues
MKTFKSAEVLIIALLAATGGAAGSYFAVSRVSAPAAPSTPAAAPRPANAPANSEAPLPPLPTSLGSDELDNIAVYERVSP
AVVNITTTVLRYDYFSRAVPEQGSGSGSILDAQGRILTNYHVVRSPKSRLEVTLANGKRYRARLVGADPSNDLAVIQLED
PPPNLTTITLGESSNLQVGRKVLAIGNPFGLERTLTTGVISALERDLASERAGRTLRNLIQTDAAINPGNSGGPLLDSQG
RLIGVNTAIFSTSGSSAGIGFAVPVDTVRQVLPELISRGTVRRASLGVQVLPLSPMVVETLKLSVKEGALVAAVVPGGAA
ARAGLRAGRLETIDGNLQLPVGADVIVAIDRVAIKDAQDLINQIQKHKPGDKVTLTIVRNNAEVQVPVTLGELREQLEEQ
>Mature_400_residues
MKTFKSAEVLIIALLAATGGAAGSYFAVSRVSAPAAPSTPAAAPRPANAPANSEAPLPPLPTSLGSDELDNIAVYERVSP
AVVNITTTVLRYDYFSRAVPEQGSGSGSILDAQGRILTNYHVVRSPKSRLEVTLANGKRYRARLVGADPSNDLAVIQLED
PPPNLTTITLGESSNLQVGRKVLAIGNPFGLERTLTTGVISALERDLASERAGRTLRNLIQTDAAINPGNSGGPLLDSQG
RLIGVNTAIFSTSGSSAGIGFAVPVDTVRQVLPELISRGTVRRASLGVQVLPLSPMVVETLKLSVKEGALVAAVVPGGAA
ARAGLRAGRLETIDGNLQLPVGADVIVAIDRVAIKDAQDLINQIQKHKPGDKVTLTIVRNNAEVQVPVTLGELREQLEEQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=330, Percent_Identity=33.6363636363636, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24308541, Length=318, Percent_Identity=35.8490566037736, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4506141, Length=337, Percent_Identity=32.6409495548961, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI7019477, Length=310, Percent_Identity=35.4838709677419, Blast_Score=143, Evalue=4e-34,
Organism=Escherichia coli, GI1789629, Length=354, Percent_Identity=35.8757062146893, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1786356, Length=297, Percent_Identity=38.3838383838384, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789630, Length=325, Percent_Identity=33.2307692307692, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24646839, Length=318, Percent_Identity=32.3899371069182, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41744; Mature: 41744

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFKSAEVLIIALLAATGGAAGSYFAVSRVSAPAAPSTPAAAPRPANAPANSEAPLPPL
CCCCCCHHHEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTSLGSDELDNIAVYERVSPAVVNITTTVLRYDYFSRAVPEQGSGSGSILDAQGRILTNY
CCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEE
HVVRSPKSRLEVTLANGKRYRARLVGADPSNDLAVIQLEDPPPNLTTITLGESSNLQVGR
EEEECCCHHEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCE
KVLAIGNPFGLERTLTTGVISALERDLASERAGRTLRNLIQTDAAINPGNSGGPLLDSQG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCC
RLIGVNTAIFSTSGSSAGIGFAVPVDTVRQVLPELISRGTVRRASLGVQVLPLSPMVVET
CEEEEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHCCCEEEHHCCEEEECCCHHHHHH
LKLSVKEGALVAAVVPGGAAARAGLRAGRLETIDGNLQLPVGADVIVAIDRVAIKDAQDL
HHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEECCCEEECCCCCEEEEEHHHHHHHHHHH
INQIQKHKPGDKVTLTIVRNNAEVQVPVTLGELREQLEEQ
HHHHHHCCCCCEEEEEEEECCCEEEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MKTFKSAEVLIIALLAATGGAAGSYFAVSRVSAPAAPSTPAAAPRPANAPANSEAPLPPL
CCCCCCHHHEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PTSLGSDELDNIAVYERVSPAVVNITTTVLRYDYFSRAVPEQGSGSGSILDAQGRILTNY
CCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEE
HVVRSPKSRLEVTLANGKRYRARLVGADPSNDLAVIQLEDPPPNLTTITLGESSNLQVGR
EEEECCCHHEEEEEECCCEEEEEEECCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCE
KVLAIGNPFGLERTLTTGVISALERDLASERAGRTLRNLIQTDAAINPGNSGGPLLDSQG
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCC
RLIGVNTAIFSTSGSSAGIGFAVPVDTVRQVLPELISRGTVRRASLGVQVLPLSPMVVET
CEEEEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHCCCEEEHHCCEEEECCCHHHHHH
LKLSVKEGALVAAVVPGGAAARAGLRAGRLETIDGNLQLPVGADVIVAIDRVAIKDAQDL
HHHHHCCCCEEEEECCCCHHHHHCCCCCCEEEECCCEEECCCCCEEEEEHHHHHHHHHHH
INQIQKHKPGDKVTLTIVRNNAEVQVPVTLGELREQLEEQ
HHHHHHCCCCCEEEEEEEECCCEEEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]