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The map label for this gene is czcC [H]

Identifier: 37521598

GI number: 37521598

Start: 2177572

End: 2178882

Strand: Direct

Name: czcC [H]

Synonym: glr2029

Alternate gene names: 37521598

Gene position: 2177572-2178882 (Clockwise)

Preceding gene: 37521597

Following gene: 37521599

Centisome position: 46.74

GC content: 67.58

Gene sequence:

>1311_bases
ATGCAAAATCGTGTTAGATTCTGCGCAGCAATGAGAAAGCTTGTGCGTCGCTGGGTTGCGGGTGTGGTGTTGGCGTTGTT
GCTGCCGAAGGCGGCGGCAGCCCAGGTCTTGGAGCTGGAGCAGGCTTTTGAGCTGGCCCTGGTCAAAAGTCCGCAGGCGA
TGGCGCTCGGGCGGCGGCTGGCGGTGAGCGAGGCGGAGGTGCTGGTGGCCGGGGCGGTGCTCAACCCTTCGATCGGGGCC
ACTTTTGAGAGTGCCGGGGCCGAAAACCGCAGCAACGTGCCCTATATCGAACAGACATTTGAACTCGGGGGCAAGCGCGA
CGCCCGGTTGGCGGTAGCCGACAGCCAGGTGGCCATCACCCGGGTGCAGATCGCCGAGGCGCTGCGGGAACTGCGCGCCC
AGGTGCGCAGAGCCTACGCCGAATTGTTGGTGGTGCGCGCCGGTTCCGAGGCTCTGCAGGAAGTAGCGGCGGCGGGGGAG
CGACTGCAGGTGGTGGCGGCCCAGCGCTTTCGCCTCGGGGACATTCCTGAACTGGATCTGATCCGCGCCCGGCAAGAACT
GGCCCTGGCGCAAAACGAACTGCAGTTGGCCCGTTCGCGCGAAGCCGCTGCCCGTATCCAGCTCAACACGCTGATCGGCC
GTGACCCCGGAGCGGCGGTGACAGTGCCGACGGTGGCCCAGTTTTCGCTGCGGGTCGAAAACGACAGCCTGCTGCCCCCC
GACAACCGGCCCTCGGGCGAGCGCGAAGACAAACTGCGCGGTTTGATCGCCCTGGCCCTCGCCAGCCGCGCCGATTTGCA
GGTGTTGGGAGGCCAGGTGGCCTTGGCTGGAGCCGAGCGGCGGCTCGCCGAGGCTGAGCGCGCCCCGGATCTGCGCGTCG
GTGCCGGGCCGCGGCTCTCCTTTGGCGAAACGCTGCAGGTGGGGGCGGCGGCGGCGGTGAACGTGAACTTTCCGCTCTGG
TACGCCCAGCAGGGCCAGATCGCCCGGGCCGAGGCGAGCGCCAGGCAACTCGAAACCGAGCGCGAGGCGCTGGTGGCGCG
CATCAAAGCCGAAGTCGAGTCGGCTTTTGTGCGGGTGCTCAGTGCCCGCGAGCAACAGCAAATTTACGAGCAGGGGCTGC
TGCCCACCGCCCGCACCGTCGAGCAGACGGCCCGCCTGGCCTACGAGCGGGGCAAGGCGGATCTGACGGTGGCCATCGGC
GCCCAGACCACCGGCAACCTGACCCGCAACCGCTACTACCAGTCGATCCTCGAATACCAGACGGCCCTGGCCGATCTGGA
AAAGGCGATCGGTGTTCCCCTCACCACCTGA

Upstream 100 bases:

>100_bases
ATGACCGCCCTCGGGCCGCTCGCCCTCACCTGGTTCGTCTTCGATCTGCCCCACCTGCTGCAGCTGCCCTGAGCCGCTCG
ATCCTGGCTTTTTGCAGTTA

Downstream 100 bases:

>100_bases
CGAGGCACCATGTCCAAGGCCATGTTCGGTATACGAATCGTCGGGTCGGCCGCTCTGCTAGCCGGAGTGCTTTATGCCAC
CCCGGTCCTGGCCCATGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MQNRVRFCAAMRKLVRRWVAGVVLALLLPKAAAAQVLELEQAFELALVKSPQAMALGRRLAVSEAEVLVAGAVLNPSIGA
TFESAGAENRSNVPYIEQTFELGGKRDARLAVADSQVAITRVQIAEALRELRAQVRRAYAELLVVRAGSEALQEVAAAGE
RLQVVAAQRFRLGDIPELDLIRARQELALAQNELQLARSREAAARIQLNTLIGRDPGAAVTVPTVAQFSLRVENDSLLPP
DNRPSGEREDKLRGLIALALASRADLQVLGGQVALAGAERRLAEAERAPDLRVGAGPRLSFGETLQVGAAAAVNVNFPLW
YAQQGQIARAEASARQLETEREALVARIKAEVESAFVRVLSAREQQQIYEQGLLPTARTVEQTARLAYERGKADLTVAIG
AQTTGNLTRNRYYQSILEYQTALADLEKAIGVPLTT

Sequences:

>Translated_436_residues
MQNRVRFCAAMRKLVRRWVAGVVLALLLPKAAAAQVLELEQAFELALVKSPQAMALGRRLAVSEAEVLVAGAVLNPSIGA
TFESAGAENRSNVPYIEQTFELGGKRDARLAVADSQVAITRVQIAEALRELRAQVRRAYAELLVVRAGSEALQEVAAAGE
RLQVVAAQRFRLGDIPELDLIRARQELALAQNELQLARSREAAARIQLNTLIGRDPGAAVTVPTVAQFSLRVENDSLLPP
DNRPSGEREDKLRGLIALALASRADLQVLGGQVALAGAERRLAEAERAPDLRVGAGPRLSFGETLQVGAAAAVNVNFPLW
YAQQGQIARAEASARQLETEREALVARIKAEVESAFVRVLSAREQQQIYEQGLLPTARTVEQTARLAYERGKADLTVAIG
AQTTGNLTRNRYYQSILEYQTALADLEKAIGVPLTT
>Mature_436_residues
MQNRVRFCAAMRKLVRRWVAGVVLALLLPKAAAAQVLELEQAFELALVKSPQAMALGRRLAVSEAEVLVAGAVLNPSIGA
TFESAGAENRSNVPYIEQTFELGGKRDARLAVADSQVAITRVQIAEALRELRAQVRRAYAELLVVRAGSEALQEVAAAGE
RLQVVAAQRFRLGDIPELDLIRARQELALAQNELQLARSREAAARIQLNTLIGRDPGAAVTVPTVAQFSLRVENDSLLPP
DNRPSGEREDKLRGLIALALASRADLQVLGGQVALAGAERRLAEAERAPDLRVGAGPRLSFGETLQVGAAAAVNVNFPLW
YAQQGQIARAEASARQLETEREALVARIKAEVESAFVRVLSAREQQQIYEQGLLPTARTVEQTARLAYERGKADLTVAIG
AQTTGNLTRNRYYQSILEYQTALADLEKAIGVPLTT

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 47184; Mature: 47184

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRVRFCAAMRKLVRRWVAGVVLALLLPKAAAAQVLELEQAFELALVKSPQAMALGRRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVSEAEVLVAGAVLNPSIGATFESAGAENRSNVPYIEQTFELGGKRDARLAVADSQVAIT
HHCHHHEEEEEEEECCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHH
RVQIAEALRELRAQVRRAYAELLVVRAGSEALQEVAAAGERLQVVAAQRFRLGDIPELDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEHHHHHHHCCCCCCCHHH
IRARQELALAQNELQLARSREAAARIQLNTLIGRDPGAAVTVPTVAQFSLRVENDSLLPP
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCEEEECCCEEEEEEECCCCCCCC
DNRPSGEREDKLRGLIALALASRADLQVLGGQVALAGAERRLAEAERAPDLRVGAGPRLS
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEECCHHHHHHHHHCCCCCEECCCCCCC
FGETLQVGAAAAVNVNFPLWYAQQGQIARAEASARQLETEREALVARIKAEVESAFVRVL
CCCHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAREQQQIYEQGLLPTARTVEQTARLAYERGKADLTVAIGAQTTGNLTRNRYYQSILEYQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
TALADLEKAIGVPLTT
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQNRVRFCAAMRKLVRRWVAGVVLALLLPKAAAAQVLELEQAFELALVKSPQAMALGRRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVSEAEVLVAGAVLNPSIGATFESAGAENRSNVPYIEQTFELGGKRDARLAVADSQVAIT
HHCHHHEEEEEEEECCCCCCCCHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHH
RVQIAEALRELRAQVRRAYAELLVVRAGSEALQEVAAAGERLQVVAAQRFRLGDIPELDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEHHHHHHHCCCCCCCHHH
IRARQELALAQNELQLARSREAAARIQLNTLIGRDPGAAVTVPTVAQFSLRVENDSLLPP
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCEEEECCCEEEEEEECCCCCCCC
DNRPSGEREDKLRGLIALALASRADLQVLGGQVALAGAERRLAEAERAPDLRVGAGPRLS
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEECCHHHHHHHHHCCCCCEECCCCCCC
FGETLQVGAAAAVNVNFPLWYAQQGQIARAEASARQLETEREALVARIKAEVESAFVRVL
CCCHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAREQQQIYEQGLLPTARTVEQTARLAYERGKADLTVAIGAQTTGNLTRNRYYQSILEYQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
TALADLEKAIGVPLTT
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]