Click here to switch to the map view.

The map label for this gene is minD [H]

Identifier: 37521562

GI number: 37521562

Start: 2141566

End: 2142372

Strand: Direct

Name: minD [H]

Synonym: gvip269

Alternate gene names: 37521562

Gene position: 2141566-2142372 (Clockwise)

Preceding gene: 37521561

Following gene: 37521563

Centisome position: 45.97

GC content: 64.56

Gene sequence:

>807_bases
ATGAGCGGCAAAGTAATCGTCATTACCTCGGGCAAGGGCGGCGTCGGCAAGACGACCTCCTCGGCCAATCTCGGGATGGC
CCTCGCCTCCCGCGGCAAGTCCGTGGTGCTCATCGACGCCGACTTTGGGCTGCGCAATCTGGATCTGCTGCTGGGTCTCG
AAAATCGCGTAGTCTATACTATTCTAGAAGTTCTCGAAGGCGAGTGCCGTCTGGAGCAGGCCCTCGTGCGCGACAAGCGC
CAGCCGGGGCTGGCCCTGTTGCCGGCGGTTCAGCGCCGCGACAAGTCGGCGGTCACCCCCGAGCAGATGCAGGACCTCAC
CGGTCGCCTCGCCGAGATGTTCAACTACGTGCTCATCGACTGTCCGGCGGGCATCGAGCAGGGATTTCGCAACGCGATCT
CGGGCGCCCACACGGCGATCGTGGTGACCACACCGGAGGTCTCGGCGGTGCGCGACGCGGACCGGGTGATTGGGCTATTG
GGTGCGGCGGGGGTGGGCGAACCGCGGCTGGTGATCAACCGTTACCGCCCGCAACTGGCCCAGACCAACGACTTGATGTC
GGTGGACGACGTGCTGGAGATTCTGGCGGTGAAGTTGCTCGGAGTCGTCCCCGAGGACGAGCAGGTGATTACGACCACCA
ACCGCGGCGAACCGATCGTGCTGTCCGCCAGTCCGCCGCCCGCGGGCCAGGCCTTTATCAACATCGCCCGCCGCCTCGAG
GGTGAGGATGTGCCGTTGATGGAATTCAAGCTGCCTGCAAGCAACGGCTTTATCGCCCGCTTGCGCGCCCTATTTACCGG
ACGCTGA

Upstream 100 bases:

>100_bases
CCGACGAACCGCCCGCCGCCCCGCAGCCGGAGGTGGCCTACATTCAAGACAACACCATTCATATCGCTATTACAACGGAG
TTTGCCCGGAGGTGGTAAAC

Downstream 100 bases:

>100_bases
GGAGATTTCGATGGTCTTCGATCTGCTCGAACGCCTGTTTAACCGCAACAAGACCGGCAGTGCCACCGTCGCCAAAGATC
GCCTCAAGATGGTCCTGGCG

Product: septum site-determining protein

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSGKVIVITSGKGGVGKTTSSANLGMALASRGKSVVLIDADFGLRNLDLLLGLENRVVYTILEVLEGECRLEQALVRDKR
QPGLALLPAVQRRDKSAVTPEQMQDLTGRLAEMFNYVLIDCPAGIEQGFRNAISGAHTAIVVTTPEVSAVRDADRVIGLL
GAAGVGEPRLVINRYRPQLAQTNDLMSVDDVLEILAVKLLGVVPEDEQVITTTNRGEPIVLSASPPPAGQAFINIARRLE
GEDVPLMEFKLPASNGFIARLRALFTGR

Sequences:

>Translated_268_residues
MSGKVIVITSGKGGVGKTTSSANLGMALASRGKSVVLIDADFGLRNLDLLLGLENRVVYTILEVLEGECRLEQALVRDKR
QPGLALLPAVQRRDKSAVTPEQMQDLTGRLAEMFNYVLIDCPAGIEQGFRNAISGAHTAIVVTTPEVSAVRDADRVIGLL
GAAGVGEPRLVINRYRPQLAQTNDLMSVDDVLEILAVKLLGVVPEDEQVITTTNRGEPIVLSASPPPAGQAFINIARRLE
GEDVPLMEFKLPASNGFIARLRALFTGR
>Mature_267_residues
SGKVIVITSGKGGVGKTTSSANLGMALASRGKSVVLIDADFGLRNLDLLLGLENRVVYTILEVLEGECRLEQALVRDKRQ
PGLALLPAVQRRDKSAVTPEQMQDLTGRLAEMFNYVLIDCPAGIEQGFRNAISGAHTAIVVTTPEVSAVRDADRVIGLLG
AAGVGEPRLVINRYRPQLAQTNDLMSVDDVLEILAVKLLGVVPEDEQVITTTNRGEPIVLSASPPPAGQAFINIARRLEG
EDVPLMEFKLPASNGFIARLRALFTGR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=256, Percent_Identity=24.609375, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787423, Length=267, Percent_Identity=46.4419475655431, Blast_Score=227, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24667611, Length=178, Percent_Identity=30.3370786516854, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28719; Mature: 28588

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKVIVITSGKGGVGKTTSSANLGMALASRGKSVVLIDADFGLRNLDLLLGLENRVVYT
CCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEEEEEECCCHHHHH
ILEVLEGECRLEQALVRDKRQPGLALLPAVQRRDKSAVTPEQMQDLTGRLAEMFNYVLID
HHHHHCCHHHHHHHHHHCCCCCCEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEE
CPAGIEQGFRNAISGAHTAIVVTTPEVSAVRDADRVIGLLGAAGVGEPRLVINRYRPQLA
CCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHH
QTNDLMSVDDVLEILAVKLLGVVPEDEQVITTTNRGEPIVLSASPPPAGQAFINIARRLE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCC
GEDVPLMEFKLPASNGFIARLRALFTGR
CCCCCEEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SGKVIVITSGKGGVGKTTSSANLGMALASRGKSVVLIDADFGLRNLDLLLGLENRVVYT
CCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEEEEEECCCHHHHH
ILEVLEGECRLEQALVRDKRQPGLALLPAVQRRDKSAVTPEQMQDLTGRLAEMFNYVLID
HHHHHCCHHHHHHHHHHCCCCCCEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEE
CPAGIEQGFRNAISGAHTAIVVTTPEVSAVRDADRVIGLLGAAGVGEPRLVINRYRPQLA
CCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCCHH
QTNDLMSVDDVLEILAVKLLGVVPEDEQVITTTNRGEPIVLSASPPPAGQAFINIARRLE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCC
GEDVPLMEFKLPASNGFIARLRALFTGR
CCCCCEEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]