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The map label for this gene is minC

Identifier: 37521561

GI number: 37521561

Start: 2140727

End: 2141563

Strand: Direct

Name: minC

Synonym: gvip268

Alternate gene names: 37521561

Gene position: 2140727-2141563 (Clockwise)

Preceding gene: 37521559

Following gene: 37521562

Centisome position: 45.95

GC content: 65.71

Gene sequence:

>837_bases
GTGTACATATCAAATCAAATCGATCCGGAATGGCCGCGAAGCACAGGCTGCGGCCCGGTAGGCGCAATATCCCGTGCTAC
ACTAATCTGCAACCTTTGCGCCCTTGCCAGAAGCCGCCCGGCCATGCAGACTCTGCCCAATTCCCTCCCCACCCAGGTTA
CCTTCAAGGGGACTCTCGAAGGGTTACGGCTGCTCATCCCGGTCGCTTTGCCCTGGGAAGAAGTGGTGCTGCAACTGCAG
CACCGGCTCAACGCCGGGGAGCGCCTCTGGCAGGGAGGGGCGGTGGTGATTTTGGAAGTCGGCGAACGCCTGCTGGACGG
CCCGCAACTGCAGGCCGTCACCGAAATGCTCACAGCCCAACAGCTGCACCTGATGCGGGTGCGCACCGTGCGTCGCCAGA
CGGCGGTGGCGGCGGCGGTGGCCGGGCTGTCCGTCGAGCAGCAGGAGGCTCCTCCGGAGGAGAACCCCGACAAACCCCCG
GCCCTGCGCGGGCTGGCCGAACCGCTCTACCTGCAGACGACCCTGCGCTCGGGGATGAGCCTGGTGCATCCCGGCACGGT
GATCGTGGTAGGCGATGTCAACCCGGGTGCAGAGATCGTCGCCGACGGCGACATTCTCGTGTGGGGCACCCTCAGGGGCG
TCGCCCACGCCGGTGCCCACGGCAACACGCGGGCGCTGATTTTTGCCTTGCGCCTCAGGCCCATCCAGTTGCGCATCGCC
GATCGCGTGGCGCGCGCCTCCGACGAACCGCCCGCCGCCCCGCAGCCGGAGGTGGCCTACATTCAAGACAACACCATTCA
TATCGCTATTACAACGGAGTTTGCCCGGAGGTGGTAA

Upstream 100 bases:

>100_bases
AATCTCCAGCACCCGATCGCCACAGGCGAGTCCGGCGGCGGCCACGATGCGATCGAGAACCGCCCCGTCGTTGAGCCAGT
GCTGACCAAAACGTTTGAGA

Downstream 100 bases:

>100_bases
ACATGAGCGGCAAAGTAATCGTCATTACCTCGGGCAAGGGCGGCGTCGGCAAGACGACCTCCTCGGCCAATCTCGGGATG
GCCCTCGCCTCCCGCGGCAA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLEGLRLLIPVALPWEEVVLQLQ
HRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQQLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPP
ALRGLAEPLYLQTTLRSGMSLVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIA
DRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW

Sequences:

>Translated_278_residues
MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLEGLRLLIPVALPWEEVVLQLQ
HRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQQLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPP
ALRGLAEPLYLQTTLRSGMSLVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIA
DRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW
>Mature_278_residues
MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLEGLRLLIPVALPWEEVVLQLQ
HRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQQLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPP
ALRGLAEPLYLQTTLRSGMSLVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIA
DRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_GLOVI (Q7NJ40)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924938.1
- ProteinModelPortal:   Q7NJ40
- SMR:   Q7NJ40
- GeneID:   2600394
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1992
- HOGENOM:   HBG399077
- OMA:   YWAGVAP
- ProtClustDB:   PRK00513
- BioCyc:   GVIO251221:GLR1992-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 30160; Mature: 30160

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEHHC
GLRLLIPVALPWEEVVLQLQHRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQ
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHH
QLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPPALRGLAEPLYLQTTLRSGMS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCE
LVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIA
EECCCEEEEEECCCCCCEEEECCCEEEEEEHHHHHHCCCCCCCEEEEEEEECCCEEEHHH
DRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW
HHHHHCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHCC
>Mature Secondary Structure
MYISNQIDPEWPRSTGCGPVGAISRATLICNLCALARSRPAMQTLPNSLPTQVTFKGTLE
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEHHC
GLRLLIPVALPWEEVVLQLQHRLNAGERLWQGGAVVILEVGERLLDGPQLQAVTEMLTAQ
CEEEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHH
QLHLMRVRTVRRQTAVAAAVAGLSVEQQEAPPEENPDKPPALRGLAEPLYLQTTLRSGMS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCE
LVHPGTVIVVGDVNPGAEIVADGDILVWGTLRGVAHAGAHGNTRALIFALRLRPIQLRIA
EECCCEEEEEECCCCCCEEEECCCEEEEEEHHHHHHCCCCCCCEEEEEEEECCCEEEHHH
DRVARASDEPPAAPQPEVAYIQDNTIHIAITTEFARRW
HHHHHCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292