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The map label for this gene is yfnA [H]

Identifier: 37521235

GI number: 37521235

Start: 1779627

End: 1781042

Strand: Reverse

Name: yfnA [H]

Synonym: gll1666

Alternate gene names: 37521235

Gene position: 1781042-1779627 (Counterclockwise)

Preceding gene: 37521236

Following gene: 37521232

Centisome position: 38.23

GC content: 62.08

Gene sequence:

>1416_bases
GTGGCCGACCTGCAAAAAGAAGGGGGCCTCGACGGAGGGTTAAAGCGCACCCTCGGTCCCATCAACTTGATTAGCCTCGG
GGTGGGTGCCATCATCGGCGCCGGGATTTTCGTGATCACGGGGCAAGCCGCTGCCCAGTACGCCGGGCCGGCCATCACCA
TTTCGTTCATCCTCGCCGCCTTCGCCTGTGCCTTTGCGGGGCTGTGCTACGCCGAATTCGCCGCTTTGCTTCCCATCTCC
GGCAGCGCCTACACCTATGCCTACGCCACTCTGGGCGAACTGGTGGCCTGGATCATCGGCTGGGATTTGATTATCGAGTA
CGCGCTATCCGCCGCGACGGTGGCTGTCGGCTGGTCGGGCTATGTGGTGAGCTTTCTGAGGGATTTCGGCATTGTTATGC
CGCCACAATTCACCGCCTCCTTCGGCCAACCGGTGACCCTCGCCGACGGTACGACGGCGGCCGGGTTGCTCAACGTCCCG
GCTGTGCTGATTATCCTGGCGCTCTCGCTGCTGTTGGTGGTGGGCGTGAGCGAATCGGCTTCCGTCAACGGCATCATTGT
CGTCGTCAAAGTGGCCGTGATCGTCGCCTTTTTGGTTTTCGGCGCCAGTTACATCGACACGGCCAACTGGACGCCGTTTA
TTCCCGAACCGGTCGAACCGGGCCGATACGGGTACTTTGGTATCCTGCGGGCGGCGGGGGTGATCTTTTTTGCCTACATC
GGTTTCGATGCGGTCTCCACCGCCGCCCAGGAAGCCAAAAATCCCCAGCGCGACATGCCCATCGGCATTCTGGGTTCACT
GGTCGTCTGCACGGTGCTCTACATCCTGGTGGCCCTCGTGCTCACCGGGATCGTCGATTACAGGCAACTGGGCGTGCCCG
ACCCGATCGCCGTGGGTGTAGACGCCATCGGCCTGGGTTGGCTCACGTTCATCGTCAAAATCGGCGCCATCGCCGGGCTC
ACCTCGGTGATGCTCGTGACCCTGTACGGCCAGACGCGCATCTTCTACACGATGAGCCGCGACGGCCTGCTGCCACCGCT
ATTTAGCGCCATCCACCCGCGCTTCAAGACCCCTTATCTCTCGACGATGCTGCTGGGTCTTTTTGTGAGCGTCGTGGCAG
GCTTGGTCCCCCTGGGCATCCTGGGAGAACTGGTGAGCATCGGCACGCTGTTCGCCTTTATCGTCGTGAGCGCCGGAGTG
CTCTTTTTGCGCTACCGCCAGCCGGATCTGCCCCGGCCTTTTCGCTGTCCGCTGGTGCCGTGGGTACCGCTTGCCAGCAT
CGTCGCCTGCCTGGCGTTGATGTCCGGGCTACCTGCCGACACCTGGCTGCGGCTGTTTGCCTGGCTCGGGCTGGGATTAC
TGGTTTACTTCGTCTACGGGCGCGTGCACAGCAAGTTGCAATCGAGAAGAGCTTGA

Upstream 100 bases:

>100_bases
GCGCAGGCCCGACAACGTTCAAGCGGCGGTGTTTAAATAGTTTCAACGTTCTGCCGGGAGAAAAGCGTTGACCCTGAGTC
GATATCTTCTCAAAAAAACC

Downstream 100 bases:

>100_bases
TTGATCGTTGCTCGGAAGCCGGGCGACCTTGAGGATAATCTCCCACTCCCCGGGACTTACCGGCAGCACCGAGAGGCGGC
TGCCGCGCCGGAGCAACGGC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MADLQKEGGLDGGLKRTLGPINLISLGVGAIIGAGIFVITGQAAAQYAGPAITISFILAAFACAFAGLCYAEFAALLPIS
GSAYTYAYATLGELVAWIIGWDLIIEYALSAATVAVGWSGYVVSFLRDFGIVMPPQFTASFGQPVTLADGTTAAGLLNVP
AVLIILALSLLLVVGVSESASVNGIIVVVKVAVIVAFLVFGASYIDTANWTPFIPEPVEPGRYGYFGILRAAGVIFFAYI
GFDAVSTAAQEAKNPQRDMPIGILGSLVVCTVLYILVALVLTGIVDYRQLGVPDPIAVGVDAIGLGWLTFIVKIGAIAGL
TSVMLVTLYGQTRIFYTMSRDGLLPPLFSAIHPRFKTPYLSTMLLGLFVSVVAGLVPLGILGELVSIGTLFAFIVVSAGV
LFLRYRQPDLPRPFRCPLVPWVPLASIVACLALMSGLPADTWLRLFAWLGLGLLVYFVYGRVHSKLQSRRA

Sequences:

>Translated_471_residues
MADLQKEGGLDGGLKRTLGPINLISLGVGAIIGAGIFVITGQAAAQYAGPAITISFILAAFACAFAGLCYAEFAALLPIS
GSAYTYAYATLGELVAWIIGWDLIIEYALSAATVAVGWSGYVVSFLRDFGIVMPPQFTASFGQPVTLADGTTAAGLLNVP
AVLIILALSLLLVVGVSESASVNGIIVVVKVAVIVAFLVFGASYIDTANWTPFIPEPVEPGRYGYFGILRAAGVIFFAYI
GFDAVSTAAQEAKNPQRDMPIGILGSLVVCTVLYILVALVLTGIVDYRQLGVPDPIAVGVDAIGLGWLTFIVKIGAIAGL
TSVMLVTLYGQTRIFYTMSRDGLLPPLFSAIHPRFKTPYLSTMLLGLFVSVVAGLVPLGILGELVSIGTLFAFIVVSAGV
LFLRYRQPDLPRPFRCPLVPWVPLASIVACLALMSGLPADTWLRLFAWLGLGLLVYFVYGRVHSKLQSRRA
>Mature_470_residues
ADLQKEGGLDGGLKRTLGPINLISLGVGAIIGAGIFVITGQAAAQYAGPAITISFILAAFACAFAGLCYAEFAALLPISG
SAYTYAYATLGELVAWIIGWDLIIEYALSAATVAVGWSGYVVSFLRDFGIVMPPQFTASFGQPVTLADGTTAAGLLNVPA
VLIILALSLLLVVGVSESASVNGIIVVVKVAVIVAFLVFGASYIDTANWTPFIPEPVEPGRYGYFGILRAAGVIFFAYIG
FDAVSTAAQEAKNPQRDMPIGILGSLVVCTVLYILVALVLTGIVDYRQLGVPDPIAVGVDAIGLGWLTFIVKIGAIAGLT
SVMLVTLYGQTRIFYTMSRDGLLPPLFSAIHPRFKTPYLSTMLLGLFVSVVAGLVPLGILGELVSIGTLFAFIVVSAGVL
FLRYRQPDLPRPFRCPLVPWVPLASIVACLALMSGLPADTWLRLFAWLGLGLLVYFVYGRVHSKLQSRRA

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=36.9411764705882, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=36.9411764705882, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=36.7058823529412, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI4507047, Length=431, Percent_Identity=35.7308584686775, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI114326544, Length=423, Percent_Identity=35.9338061465721, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI114326550, Length=423, Percent_Identity=35.9338061465721, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI181337167, Length=399, Percent_Identity=36.3408521303258, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI110347453, Length=413, Percent_Identity=34.1404358353511, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI186910308, Length=407, Percent_Identity=26.5356265356265, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI186910306, Length=407, Percent_Identity=26.5356265356265, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI186910304, Length=407, Percent_Identity=26.5356265356265, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI115648063, Length=412, Percent_Identity=24.7572815533981, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI115648022, Length=412, Percent_Identity=24.7572815533981, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI71979932, Length=434, Percent_Identity=25.3456221198157, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33286428, Length=435, Percent_Identity=24.8275862068966, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI7657683, Length=373, Percent_Identity=24.3967828418231, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI187423910, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7657591, Length=484, Percent_Identity=24.3801652892562, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71999149, Length=443, Percent_Identity=25.2821670428894, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI87081708, Length=460, Percent_Identity=23.0434782608696, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87081869, Length=413, Percent_Identity=22.7602905569007, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788480, Length=465, Percent_Identity=23.8709677419355, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082250, Length=381, Percent_Identity=26.509186351706, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786694, Length=401, Percent_Identity=25.4364089775561, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082023, Length=419, Percent_Identity=23.3890214797136, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1789017, Length=377, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081915, Length=421, Percent_Identity=23.7529691211401, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786602, Length=482, Percent_Identity=22.6141078838174, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367353, Length=407, Percent_Identity=22.6044226044226, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=404, Percent_Identity=35.6435643564356, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17531343, Length=409, Percent_Identity=34.718826405868, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=409, Percent_Identity=32.518337408313, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17540018, Length=465, Percent_Identity=25.1612903225806, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17568033, Length=477, Percent_Identity=24.9475890985325, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193208714, Length=429, Percent_Identity=21.6783216783217, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=429, Percent_Identity=21.6783216783217, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993915, Length=424, Percent_Identity=22.4056603773585, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17537453, Length=373, Percent_Identity=24.1286863270777, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=420, Percent_Identity=24.047619047619, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=420, Percent_Identity=24.047619047619, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=357, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=418, Percent_Identity=20.5741626794258, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982608, Length=418, Percent_Identity=20.5741626794258, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=34.7826086956522, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=34.7826086956522, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24668806, Length=416, Percent_Identity=37.2596153846154, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI21356285, Length=416, Percent_Identity=37.2596153846154, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24668802, Length=416, Percent_Identity=37.2596153846154, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24667468, Length=440, Percent_Identity=35, Blast_Score=248, Evalue=6e-66,
Organism=Drosophila melanogaster, GI281366235, Length=414, Percent_Identity=34.2995169082126, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI116007820, Length=414, Percent_Identity=34.2995169082126, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI116007818, Length=424, Percent_Identity=33.7264150943396, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI85725152, Length=424, Percent_Identity=33.7264150943396, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI161077963, Length=416, Percent_Identity=35.5769230769231, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI221331183, Length=429, Percent_Identity=25.6410256410256, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17647653, Length=429, Percent_Identity=25.6410256410256, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24664379, Length=429, Percent_Identity=25.6410256410256, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550968, Length=432, Percent_Identity=27.5462962962963, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921172, Length=432, Percent_Identity=27.5462962962963, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357367, Length=445, Percent_Identity=24.9438202247191, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24651635, Length=441, Percent_Identity=25.1700680272109, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24651633, Length=441, Percent_Identity=25.1700680272109, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24641995, Length=424, Percent_Identity=21.6981132075472, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641993, Length=424, Percent_Identity=21.6981132075472, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49751; Mature: 49619

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLQKEGGLDGGLKRTLGPINLISLGVGAIIGAGIFVITGQAAAQYAGPAITISFILAA
CCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCHHEEECCHHHHHCCCHHHHHHHHHH
FACAFAGLCYAEFAALLPISGSAYTYAYATLGELVAWIIGWDLIIEYALSAATVAVGWSG
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YVVSFLRDFGIVMPPQFTASFGQPVTLADGTTAAGLLNVPAVLIILALSLLLVVGVSESA
HHHHHHHHCCCCCCCCHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVNGIIVVVKVAVIVAFLVFGASYIDTANWTPFIPEPVEPGRYGYFGILRAAGVIFFAYI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GFDAVSTAAQEAKNPQRDMPIGILGSLVVCTVLYILVALVLTGIVDYRQLGVPDPIAVGV
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCH
DAIGLGWLTFIVKIGAIAGLTSVMLVTLYGQTRIFYTMSRDGLLPPLFSAIHPRFKTPYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHCCCCCCHHH
STMLLGLFVSVVAGLVPLGILGELVSIGTLFAFIVVSAGVLFLRYRQPDLPRPFRCPLVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCC
WVPLASIVACLALMSGLPADTWLRLFAWLGLGLLVYFVYGRVHSKLQSRRA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADLQKEGGLDGGLKRTLGPINLISLGVGAIIGAGIFVITGQAAAQYAGPAITISFILAA
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCHHEEECCHHHHHCCCHHHHHHHHHH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HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]