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The map label for this gene is dhaAF [H]

Identifier: 37520991

GI number: 37520991

Start: 1527238

End: 1528116

Strand: Direct

Name: dhaAF [H]

Synonym: glr1422

Alternate gene names: 37520991

Gene position: 1527238-1528116 (Clockwise)

Preceding gene: 37520990

Following gene: 37520992

Centisome position: 32.78

GC content: 59.73

Gene sequence:

>879_bases
ATGAAAATACGCTACGGGTTTCGACAGGTCGGCGATGTCGAAGTGTTCTACCGCGAGGCTGGGTCAAGCGATGCGCCAGT
GATACTGCTGTTGCACGGCTTTCCAACCGCTAGCCACATGTTCCGCGACCTGATCCCTCTCCTTGCCGATCGCTTTCGGC
TCGTCGCGCCGGATCTGCCTGGTTTCGGACAGACCAAGGCACCGCCGCGCGGGACGTTCGACTACACGTTCGACCGCCTT
GCCGACGTGATCGAGGGCTTCGTCGATGCTTTGTCGCTCGATCAATACGTGCTCTACATCTTCGACTACGGTGCGCCGAT
AGGACTGCGTCTGGCGATGCGCCATTCTGAACGGATATCTGCGATCGTCTCGCAGAACGGCAACGCCTACATTGAGGGTT
TCAGTGACGAATGGGGCACGTGGGAGTCCTATTGGCGCGAACCGAGCGCAGCGAACCGGGAAGCCTGCCGACCCTCGCTC
GCGCCGGACATAATCCGGAACTGGCAGTATGGTACCGGAGCCGATCCAAACCTTTTGTCGCCCGACGGCTACGAACTTGA
CATCGCCTACATGGGGCGACCGGGCGCGGAGGAGATCCAGCTCGACCTAATCCTCGACTACCGCAGCAACGTCGCGCTCT
ATCCGGTCTTCCAGTCCTACTTTCGCGAGCACCGTCCGCCGCTTCTCGCCGTTTGGGGCCGTCATGATCCGGCGTTTCTG
CCCGCTGGTGCCGCCGCTTATCAGCGAGATCTCCCGGATGCAAAGATTCATCTGCTCGATGCCGGACATTTCGCGCTGGA
GACACATGCGGAGGAGGTGGCAATTTTGATCCGCACGTTCCTCGATAGCGCGATCGGTTCCACCACAGTGAAAATCTAA

Upstream 100 bases:

>100_bases
TGGCTACATCAGCGGCGGCGTAGTGGATGTGTCCGGCGGATTCCAAATCTGAGCGCCGAAGCAGCTCAAAACTTTTACAC
GTGCAATCAAAGGAAAAGAT

Downstream 100 bases:

>100_bases
CTCAGTAAAGGATGAAGTCATGACCCAAAAATATGGACCCAAGACAACAACCGACGAAGTGCTTTCCGGCATTGAACTCA
AGGGAAAGCGATTTCTGATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKIRYGFRQVGDVEVFYREAGSSDAPVILLLHGFPTASHMFRDLIPLLADRFRLVAPDLPGFGQTKAPPRGTFDYTFDRL
ADVIEGFVDALSLDQYVLYIFDYGAPIGLRLAMRHSERISAIVSQNGNAYIEGFSDEWGTWESYWREPSAANREACRPSL
APDIIRNWQYGTGADPNLLSPDGYELDIAYMGRPGAEEIQLDLILDYRSNVALYPVFQSYFREHRPPLLAVWGRHDPAFL
PAGAAAYQRDLPDAKIHLLDAGHFALETHAEEVAILIRTFLDSAIGSTTVKI

Sequences:

>Translated_292_residues
MKIRYGFRQVGDVEVFYREAGSSDAPVILLLHGFPTASHMFRDLIPLLADRFRLVAPDLPGFGQTKAPPRGTFDYTFDRL
ADVIEGFVDALSLDQYVLYIFDYGAPIGLRLAMRHSERISAIVSQNGNAYIEGFSDEWGTWESYWREPSAANREACRPSL
APDIIRNWQYGTGADPNLLSPDGYELDIAYMGRPGAEEIQLDLILDYRSNVALYPVFQSYFREHRPPLLAVWGRHDPAFL
PAGAAAYQRDLPDAKIHLLDAGHFALETHAEEVAILIRTFLDSAIGSTTVKI
>Mature_292_residues
MKIRYGFRQVGDVEVFYREAGSSDAPVILLLHGFPTASHMFRDLIPLLADRFRLVAPDLPGFGQTKAPPRGTFDYTFDRL
ADVIEGFVDALSLDQYVLYIFDYGAPIGLRLAMRHSERISAIVSQNGNAYIEGFSDEWGTWESYWREPSAANREACRPSL
APDIIRNWQYGTGADPNLLSPDGYELDIAYMGRPGAEEIQLDLILDYRSNVALYPVFQSYFREHRPPLLAVWGRHDPAFL
PAGAAAYQRDLPDAKIHLLDAGHFALETHAEEVAILIRTFLDSAIGSTTVKI

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes mono- and di- chlorinated

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 2 subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17562298, Length=291, Percent_Identity=23.0240549828179, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324392, Length=279, Percent_Identity=45.8781362007168, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 32770; Mature: 32770

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRYGFRQVGDVEVFYREAGSSDAPVILLLHGFPTASHMFRDLIPLLADRFRLVAPDLP
CCCCCCCHHCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCC
GFGQTKAPPRGTFDYTFDRLADVIEGFVDALSLDQYVLYIFDYGAPIGLRLAMRHSERIS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEHHHHHHHH
AIVSQNGNAYIEGFSDEWGTWESYWREPSAANREACRPSLAPDIIRNWQYGTGADPNLLS
HHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCC
PDGYELDIAYMGRPGAEEIQLDLILDYRSNVALYPVFQSYFREHRPPLLAVWGRHDPAFL
CCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCCEEEEECCCCCCCC
PAGAAAYQRDLPDAKIHLLDAGHFALETHAEEVAILIRTFLDSAIGSTTVKI
CCCHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MKIRYGFRQVGDVEVFYREAGSSDAPVILLLHGFPTASHMFRDLIPLLADRFRLVAPDLP
CCCCCCCHHCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCC
GFGQTKAPPRGTFDYTFDRLADVIEGFVDALSLDQYVLYIFDYGAPIGLRLAMRHSERIS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEHHHHHHHH
AIVSQNGNAYIEGFSDEWGTWESYWREPSAANREACRPSLAPDIIRNWQYGTGADPNLLS
HHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCC
PDGYELDIAYMGRPGAEEIQLDLILDYRSNVALYPVFQSYFREHRPPLLAVWGRHDPAFL
CCCCEEEEEECCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHCCCCEEEEECCCCCCCC
PAGAAAYQRDLPDAKIHLLDAGHFALETHAEEVAILIRTFLDSAIGSTTVKI
CCCHHHHHHCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094681; 10735862 [H]