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The map label for this gene is sufC [H]

Identifier: 37520940

GI number: 37520940

Start: 1467146

End: 1467904

Strand: Direct

Name: sufC [H]

Synonym: glr1371

Alternate gene names: 37520940

Gene position: 1467146-1467904 (Clockwise)

Preceding gene: 37520939

Following gene: 37520941

Centisome position: 31.49

GC content: 62.32

Gene sequence:

>759_bases
ATGCTCGAAATTACCAACCTGCAGGCGCGGGTCGAAGGCAAAGCGATCCTCAAAGGAATAGATCTGACCGTCCGCCCCGG
CGAGGTGCACGCCATTATGGGTCCGAACGGCTCGGGCAAGAGTACCCTGGCCGGGGTGCTCGCCGGGCGCGAGGAGTACG
AGGTGACCGGCGGCGCGGTGCGCTATCTGGACCAGGATTTGCTCGAACTCGCCCCGGAGGAGCGCGCCCGCGCGGGACTT
TTGCTGGCCTTTCAGTACCCGGTGGAGATTCCTGGCGTGAGCAACGTCTATTTTCTAAAGGCGGCGCTCAACGCGCTGCG
CAAACATCGGGGCGAAGGCGAACTGGACGCGGTCGAATTTTTGGCCCTGGTGCGGGGGAAGCTCAAGACCGTGCAGATGG
CCGAGAGCTTTTTGCGCCGCTCGGTCAACGAGGGCTTCTCCGGGGGCGAGAAAAAGCGCAACGAAATTCTGCAGATGGCG
CTGTTGGAACCGTGCCTCGCCATTCTTGACGAGACCGATTCGGGCCTCGATATCGACGCGCTCAAAATCGTGGCGGATGG
TGTGAATGGCCTGCGCTCGCCCGAGCGCTCCTTTCTGGTCATCACCCACTACCAGAGGCTGCTCGATTACATCGTGCCCG
ACTTCGTGCACGTGCTGATGAACGGCCGCATCGTGCGCTCGGGTGGGCGTGAACTGGCCCTCGAACTCGAAGAAAAAGGC
TACGGCTGGCTCGAAGCGGAGGTGACCGTCGGTGCCTAG

Upstream 100 bases:

>100_bases
AGAAGTGTTCCGCGAGTTGCCGATGGAATTTGCGGTCGAAGCCCAGAAGCTGCTCGAAGTCAGCCTCGAAGGCAGCGTCG
GCTAAATGGAGAACCACCCT

Downstream 100 bases:

>100_bases
GGAGTCTGCCATGCCCGCTGCAATCGAAAAAAACGTGTTCGTTCCCGACTTCGAGCCTTTTATTGCCGCTCGCCCGGGCG
AGGCTGAAGCGGTGCTTGCC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLEITNLQARVEGKAILKGIDLTVRPGEVHAIMGPNGSGKSTLAGVLAGREEYEVTGGAVRYLDQDLLELAPEERARAGL
LLAFQYPVEIPGVSNVYFLKAALNALRKHRGEGELDAVEFLALVRGKLKTVQMAESFLRRSVNEGFSGGEKKRNEILQMA
LLEPCLAILDETDSGLDIDALKIVADGVNGLRSPERSFLVITHYQRLLDYIVPDFVHVLMNGRIVRSGGRELALELEEKG
YGWLEAEVTVGA

Sequences:

>Translated_252_residues
MLEITNLQARVEGKAILKGIDLTVRPGEVHAIMGPNGSGKSTLAGVLAGREEYEVTGGAVRYLDQDLLELAPEERARAGL
LLAFQYPVEIPGVSNVYFLKAALNALRKHRGEGELDAVEFLALVRGKLKTVQMAESFLRRSVNEGFSGGEKKRNEILQMA
LLEPCLAILDETDSGLDIDALKIVADGVNGLRSPERSFLVITHYQRLLDYIVPDFVHVLMNGRIVRSGGRELALELEEKG
YGWLEAEVTVGA
>Mature_252_residues
MLEITNLQARVEGKAILKGIDLTVRPGEVHAIMGPNGSGKSTLAGVLAGREEYEVTGGAVRYLDQDLLELAPEERARAGL
LLAFQYPVEIPGVSNVYFLKAALNALRKHRGEGELDAVEFLALVRGKLKTVQMAESFLRRSVNEGFSGGEKKRNEILQMA
LLEPCLAILDETDSGLDIDALKIVADGVNGLRSPERSFLVITHYQRLLDYIVPDFVHVLMNGRIVRSGGRELALELEEKG
YGWLEAEVTVGA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=239, Percent_Identity=27.1966527196653, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI73747915, Length=193, Percent_Identity=31.6062176165803, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=65.5737704918033, Blast_Score=333, Evalue=6e-93,
Organism=Escherichia coli, GI1789672, Length=208, Percent_Identity=29.8076923076923, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=26.7241379310345, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789864, Length=241, Percent_Identity=26.1410788381743, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789891, Length=223, Percent_Identity=31.390134529148, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=231, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=219, Percent_Identity=28.310502283105, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=231, Percent_Identity=29.8701298701299, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323217, Length=199, Percent_Identity=31.1557788944724, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27568; Mature: 27568

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEITNLQARVEGKAILKGIDLTVRPGEVHAIMGPNGSGKSTLAGVLAGREEYEVTGGAV
CCEECCCHHHHCCHHHEEECCEEECCCCEEEEECCCCCCHHHHHHHHCCCHHHEECCHHH
RYLDQDLLELAPEERARAGLLLAFQYPVEIPGVSNVYFLKAALNALRKHRGEGELDAVEF
HHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
LALVRGKLKTVQMAESFLRRSVNEGFSGGEKKRNEILQMALLEPCLAILDETDSGLDIDA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LKIVADGVNGLRSPERSFLVITHYQRLLDYIVPDFVHVLMNGRIVRSGGRELALELEEKG
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCC
YGWLEAEVTVGA
CCEEEEEEEECC
>Mature Secondary Structure
MLEITNLQARVEGKAILKGIDLTVRPGEVHAIMGPNGSGKSTLAGVLAGREEYEVTGGAV
CCEECCCHHHHCCHHHEEECCEEECCCCEEEEECCCCCCHHHHHHHHCCCHHHEECCHHH
RYLDQDLLELAPEERARAGLLLAFQYPVEIPGVSNVYFLKAALNALRKHRGEGELDAVEF
HHHHHHHHHCCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
LALVRGKLKTVQMAESFLRRSVNEGFSGGEKKRNEILQMALLEPCLAILDETDSGLDIDA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LKIVADGVNGLRSPERSFLVITHYQRLLDYIVPDFVHVLMNGRIVRSGGRELALELEEKG
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCC
YGWLEAEVTVGA
CCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]