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The map label for this gene is fabF [H]

Identifier: 37520660

GI number: 37520660

Start: 1168304

End: 1169575

Strand: Reverse

Name: fabF [H]

Synonym: gll1091

Alternate gene names: 37520660

Gene position: 1169575-1168304 (Counterclockwise)

Preceding gene: 37520661

Following gene: 37520658

Centisome position: 25.1

GC content: 47.25

Gene sequence:

>1272_bases
ATGAAAAGCAGGAATCAAAGAGAGTTAAAGCGCGTTGTCGTCACAGGCATGGGATCAATTACTCCTCTACAAAATGATCC
AGAATCCTTCTGGCAGCAGTTACTTGTTGGCAGATCTGGGGTGAGTCGGATCACGTACTTTGACACATCGCATCATCGTT
GCCAGATTGCTGCTGAAGTAAAGGGGTTTGAGGCGTCAGATTATCTATCATTAAAAGCAGCTAAGCGCACCGAAAGATGT
ATTCAGTTCGCTATTGCCGGGGCTAGGCAGGCCCTTGACGATGCTCAATTTTCGATCGATGCACTGAATGCCAGTCAAGT
GGGGGTCGTGATTGGTACAGCCATTGGGGGAATCCGAATCTTCGAAGCACAAGCAAATGTTTATGCCCAGAAAGGACCAG
ATCGTTGCAGTCCCTTTTTGACGCCGATGACGATTTGCAATATGGCTGCTGCTCAGGTCGCTATTCAAATTGGAGCGACG
GGGCCATGTTTTTGCCCAGCTACTGCTTGTGCTGCCGGTTCCAATGCGATTGGAGATGCTTTTCGGTTAATTCAGTTGGG
GCATGTTCAAGCAGTGATTGCTGGAGGCACCGAAGCGCCCATCACACCATTGGTCATCGCAGGGTTTGAAGCTGCTAGAG
TTGTATCTACTCTCAATCAGGAACCGGAAAAAGCTAGTCGACCTTTTGATAAAAGTAGGGATGGATTTGTCATTGGAGAA
GGTTCAGGAATCCTTTTGCTTGAGGAACTTGAACACGCTCTCAGGCGCGGTAAAAAGATATATGCAGAATTGATCGGATA
TGGAGCTAGTTGTGATGCACATCATATCACTTCTCCTTTACCAACCGGTGCTGGGGCAGCTCAGGCAATGCGACTGGCTA
TCGAGGATGCCGACTTATCTCCTGGCCAGGTCAATTACATTAATGCCCACGGCACTAGCACCCTTGCTAACGATGCAATG
GAAATTAAAGGAATTAGTCTTGCATTTGGAGAACTAGCTCCTCTGATTCCTATCAACTCCACCAAATCGATGACTGGTCA
CCTCTTAGGAGCAGCGGGGGGGATTGAAGCTATCGCAACAATCATGACGATCACTAAGGACCAGATCCCTGCCACGCTCA
ATCTCCAAAATCCTGATACTGAATGCGATCTCGATTTTGTGACGAAGGAAAGTCGTCACAAAATTGTGGATGTAGCGATG
TCAAATTCATTTGGATTTGGGGGACATAACGTATCATTAATTTTTCGCAAGTTCCCCGGCATGCTTGAATAA

Upstream 100 bases:

>100_bases
ACAGCCCAGACGGCCCAGGTTTGCTGCAAGCCTAACCGAAGGTTGGTGTAGCAATAACCAGCTTAAGAAACTTTTCACTG
GCCGAGATAGGAAATAAGAA

Downstream 100 bases:

>100_bases
TCTACGCCGCGGTTTCCAGATTTGTACTACACGGGGTAAGCGAACGGAATGACCAATCGCCGGGCGATAGTGCTCGAACA
GTTGCTCCGGGCTCAAATGC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase beta chain

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKSRNQRELKRVVVTGMGSITPLQNDPESFWQQLLVGRSGVSRITYFDTSHHRCQIAAEVKGFEASDYLSLKAAKRTERC
IQFAIAGARQALDDAQFSIDALNASQVGVVIGTAIGGIRIFEAQANVYAQKGPDRCSPFLTPMTICNMAAAQVAIQIGAT
GPCFCPATACAAGSNAIGDAFRLIQLGHVQAVIAGGTEAPITPLVIAGFEAARVVSTLNQEPEKASRPFDKSRDGFVIGE
GSGILLLEELEHALRRGKKIYAELIGYGASCDAHHITSPLPTGAGAAQAMRLAIEDADLSPGQVNYINAHGTSTLANDAM
EIKGISLAFGELAPLIPINSTKSMTGHLLGAAGGIEAIATIMTITKDQIPATLNLQNPDTECDLDFVTKESRHKIVDVAM
SNSFGFGGHNVSLIFRKFPGMLE

Sequences:

>Translated_423_residues
MKSRNQRELKRVVVTGMGSITPLQNDPESFWQQLLVGRSGVSRITYFDTSHHRCQIAAEVKGFEASDYLSLKAAKRTERC
IQFAIAGARQALDDAQFSIDALNASQVGVVIGTAIGGIRIFEAQANVYAQKGPDRCSPFLTPMTICNMAAAQVAIQIGAT
GPCFCPATACAAGSNAIGDAFRLIQLGHVQAVIAGGTEAPITPLVIAGFEAARVVSTLNQEPEKASRPFDKSRDGFVIGE
GSGILLLEELEHALRRGKKIYAELIGYGASCDAHHITSPLPTGAGAAQAMRLAIEDADLSPGQVNYINAHGTSTLANDAM
EIKGISLAFGELAPLIPINSTKSMTGHLLGAAGGIEAIATIMTITKDQIPATLNLQNPDTECDLDFVTKESRHKIVDVAM
SNSFGFGGHNVSLIFRKFPGMLE
>Mature_423_residues
MKSRNQRELKRVVVTGMGSITPLQNDPESFWQQLLVGRSGVSRITYFDTSHHRCQIAAEVKGFEASDYLSLKAAKRTERC
IQFAIAGARQALDDAQFSIDALNASQVGVVIGTAIGGIRIFEAQANVYAQKGPDRCSPFLTPMTICNMAAAQVAIQIGAT
GPCFCPATACAAGSNAIGDAFRLIQLGHVQAVIAGGTEAPITPLVIAGFEAARVVSTLNQEPEKASRPFDKSRDGFVIGE
GSGILLLEELEHALRRGKKIYAELIGYGASCDAHHITSPLPTGAGAAQAMRLAIEDADLSPGQVNYINAHGTSTLANDAM
EIKGISLAFGELAPLIPINSTKSMTGHLLGAAGGIEAIATIMTITKDQIPATLNLQNPDTECDLDFVTKESRHKIVDVAM
SNSFGFGGHNVSLIFRKFPGMLE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=418, Percent_Identity=40.6698564593301, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=44.1379310344828, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI41872631, Length=430, Percent_Identity=25.3488372093023, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1787337, Length=409, Percent_Identity=48.1662591687042, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=35.421686746988, Blast_Score=224, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI71983541, Length=417, Percent_Identity=34.7721822541966, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI71983535, Length=257, Percent_Identity=41.2451361867704, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI212642053, Length=425, Percent_Identity=24, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=35.7777777777778, Blast_Score=257, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24644341, Length=423, Percent_Identity=40.661938534279, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI221330659, Length=363, Percent_Identity=25.3443526170799, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI19920632, Length=363, Percent_Identity=25.3443526170799, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24581345, Length=358, Percent_Identity=23.463687150838, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44825; Mature: 44825

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRNQRELKRVVVTGMGSITPLQNDPESFWQQLLVGRSGVSRITYFDTSHHRCQIAAEV
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEC
KGFEASDYLSLKAAKRTERCIQFAIAGARQALDDAQFSIDALNASQVGVVIGTAIGGIRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEE
FEAQANVYAQKGPDRCSPFLTPMTICNMAAAQVAIQIGATGPCFCPATACAAGSNAIGDA
EEECCCEEECCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHCCCCHHHHH
FRLIQLGHVQAVIAGGTEAPITPLVIAGFEAARVVSTLNQEPEKASRPFDKSRDGFVIGE
HHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEC
GSGILLLEELEHALRRGKKIYAELIGYGASCDAHHITSPLPTGAGAAQAMRLAIEDADLS
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCCCC
PGQVNYINAHGTSTLANDAMEIKGISLAFGELAPLIPINSTKSMTGHLLGAAGGIEAIAT
CCEEEEEECCCCCHHHCCCHHCCCEEEECCCCCCCEECCCCCCHHHHHEECCCHHHHHHH
IMTITKDQIPATLNLQNPDTECDLDFVTKESRHKIVDVAMSNSFGFGGHNVSLIFRKFPG
HHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCEEHEECCCC
MLE
CCC
>Mature Secondary Structure
MKSRNQRELKRVVVTGMGSITPLQNDPESFWQQLLVGRSGVSRITYFDTSHHRCQIAAEV
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEC
KGFEASDYLSLKAAKRTERCIQFAIAGARQALDDAQFSIDALNASQVGVVIGTAIGGIRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEE
FEAQANVYAQKGPDRCSPFLTPMTICNMAAAQVAIQIGATGPCFCPATACAAGSNAIGDA
EEECCCEEECCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHCCCCHHHHH
FRLIQLGHVQAVIAGGTEAPITPLVIAGFEAARVVSTLNQEPEKASRPFDKSRDGFVIGE
HHHHHHCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHCCCCHHHCCCCCCCCCCEEEEC
GSGILLLEELEHALRRGKKIYAELIGYGASCDAHHITSPLPTGAGAAQAMRLAIEDADLS
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECCCCC
PGQVNYINAHGTSTLANDAMEIKGISLAFGELAPLIPINSTKSMTGHLLGAAGGIEAIAT
CCEEEEEECCCCCHHHCCCHHCCCEEEECCCCCCCEECCCCCCHHHHHEECCCHHHHHHH
IMTITKDQIPATLNLQNPDTECDLDFVTKESRHKIVDVAMSNSFGFGGHNVSLIFRKFPG
HHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCEEHEECCCC
MLE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 11152607 [H]