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The map label for this gene is tadA [H]

Identifier: 37520622

GI number: 37520622

Start: 1126719

End: 1127171

Strand: Reverse

Name: tadA [H]

Synonym: gll1053

Alternate gene names: 37520622

Gene position: 1127171-1126719 (Counterclockwise)

Preceding gene: 37520624

Following gene: 37520620

Centisome position: 24.19

GC content: 66.23

Gene sequence:

>453_bases
GTGAAAAGTCACAGCGAGTGGATGGGTATGGCCCTGGAGCTGGCGCGCGAGGCGGGCCGGGTGGGGGAGGTACCCGTCGG
TGCGCTGGTGGTGGATGCGTCCGGAGTGCTCCTGGCTACCGGCGCCAACCGCCGCGAGCGCGACTATGACCCGACCGCCC
ACGCCGAGATCGTGGCGATGCGCGCCGCCTGCGCGAAGCTGCGCGACTGGCGGCTGACCGACTGCACGCTTTACGTCACC
CTGGAGCCCTGTGCGATGTGCGCCGGTGCGATTTTGCAATCACGCCTGGGCCTGCTCGTTTACGGCGCCGACGATCCCAA
AGCCGGAGCAGTAGGTTCGGTGCTCAACTTACCGGCGAGCGCCGTAAGCTTCCACCGCCTGCCCGTTGTTGCAGGCATTG
AAGAGCGGGCCTGCCGGGATTTGCTTTGCAGGTGGTTTGAGGAGCAAAGGTAA

Upstream 100 bases:

>100_bases
GAGCTTGGATAAGCCATTGGGGAATGGTGTAATTGGCAACACGTCAGGTTCTGGCCCTGAAGTCTCTAGGTTCGAGTCCT
AGTTCCCCAGCTAAGCCCAA

Downstream 100 bases:

>100_bases
CCGAAAAATCAAAACCCCGGCCAAGCCGTAGCCGCCGGGGCGAAAGTTACCGCTCAGGCGTCGCTTAGACGTCGAAGTAG
AGCGAGAACTCGTAGGGGTG

Product: putative cytidine and deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKSHSEWMGMALELAREAGRVGEVPVGALVVDASGVLLATGANRRERDYDPTAHAEIVAMRAACAKLRDWRLTDCTLYVT
LEPCAMCAGAILQSRLGLLVYGADDPKAGAVGSVLNLPASAVSFHRLPVVAGIEERACRDLLCRWFEEQR

Sequences:

>Translated_150_residues
MKSHSEWMGMALELAREAGRVGEVPVGALVVDASGVLLATGANRRERDYDPTAHAEIVAMRAACAKLRDWRLTDCTLYVT
LEPCAMCAGAILQSRLGLLVYGADDPKAGAVGSVLNLPASAVSFHRLPVVAGIEERACRDLLCRWFEEQR
>Mature_150_residues
MKSHSEWMGMALELAREAGRVGEVPVGALVVDASGVLLATGANRRERDYDPTAHAEIVAMRAACAKLRDWRLTDCTLYVT
LEPCAMCAGAILQSRLGLLVYGADDPKAGAVGSVLNLPASAVSFHRLPVVAGIEERACRDLLCRWFEEQR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=138, Percent_Identity=35.5072463768116, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=45.945945945946, Blast_Score=124, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=108, Percent_Identity=37.962962962963, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=110, Percent_Identity=37.2727272727273, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=120, Percent_Identity=35, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=31.2925170068027, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16225; Mature: 16225

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHSEWMGMALELAREAGRVGEVPVGALVVDASGVLLATGANRRERDYDPTAHAEIVAM
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
RAACAKLRDWRLTDCTLYVTLEPCAMCAGAILQSRLGLLVYGADDPKAGAVGSVLNLPAS
HHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCHH
AVSFHRLPVVAGIEERACRDLLCRWFEEQR
HHHHHCCCEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSHSEWMGMALELAREAGRVGEVPVGALVVDASGVLLATGANRRERDYDPTAHAEIVAM
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH
RAACAKLRDWRLTDCTLYVTLEPCAMCAGAILQSRLGLLVYGADDPKAGAVGSVLNLPAS
HHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHCCHH
AVSFHRLPVVAGIEERACRDLLCRWFEEQR
HHHHHCCCEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]