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The map label for this gene is asd [H]

Identifier: 37520586

GI number: 37520586

Start: 1091792

End: 1092760

Strand: Direct

Name: asd [H]

Synonym: glr1017

Alternate gene names: 37520586

Gene position: 1091792-1092760 (Clockwise)

Preceding gene: 37520585

Following gene: 37520587

Centisome position: 23.43

GC content: 65.12

Gene sequence:

>969_bases
GTGGGCACCGAGATGGTCAAGTTATTACAAGAGCGCCACTTTCCCCTCGCCAGTCTCAAGCTGCTTGCCTCGGAGCGTTC
TGCGGGCAAGTTGCTTGATTTTGCCGGTGAATCGCTGCCCGTTGAGGTGCTGAGGCCCGAGGCTCTCAAAGGCCAGGACA
TTGTCCTGGGTGCCACCGAGGCAGATGTGGCCCGGCAGTATGCCGGGGTGATCGTCGAAGCGGGGGGAGTGTTTGTCGAT
AACTCCAGCGCCTTTCGCCAGGATCCGGCGGTGCCGCTGGTGGTGCCGGAGGTTAACCTGGCGGATCTGACTGCCCACTG
CGGAATTGTCGCCAGCCCCAATTGCTCTACAATCCTGCTGGTGGTGGCCGTGTGGCCCCTACACCGGCGCCGGCCCCTGA
AGCGCTTGGTCGTCTCCACCTACCAGGCGGCTTCCGGGGCGGGGGCGGCGGGCATGGCGGAGCTTGAACGCCAGACGCGC
CAGGTGCTGGCGGGCGAAGTGCCCACAGCCGAGGTTTTTCCTCACCCGATCGCCTTCAATCTTTTCCCTCACAATTCGGC
TATCGGAGCGGACCGCTACTGCGAGGAAGAGCGCAAGATGGTCCACGAGACACGGCGCATCTTTCACAGCGCGGCCCTGC
CCATTGCCGTCACCTGCGTGCGCGTGCCGGTCCTGCGCGCCCACAGCGAGGCGGTCAACCTCGAATTTGAAGAGCCCTTC
CCGGTGGCGGAGGCACTGGCGCTGTTGCGCGAAGCCCCGGGATTGCAGGTGGTCGAAGATTGGGAGCGCAACCACTTTCC
GATGCCCGTCGAGGCGAGCGGCCAGGACGCGGTGTTGGTGGGGCGGGTGCGCGAGGATCTCTCCTGTCCGGGGGCTCTGG
ACCTGTGGCTTTCGGGCGATCAGATCCGCAAGGGAGCGGCCCTCAACGCCGTCCAGATTGCCGAACAGTTGGCGGGAGGG
AGGCGGTGA

Upstream 100 bases:

>100_bases
ATCAGCCCACTCTTTTGACCAAACGCACCACTGACCAACCCGTTAAGGAGGCCGATTGACAAACGCATATCGTGTCGCTG
TTCTGGGAGCCACCGGAGCA

Downstream 100 bases:

>100_bases
GCTTCGGTCGGGTGCTCACGGCGATGATCACACCCTTCGACGGCGAGGGTAATGTCCATTACGCCGAGGCCGAAAAACTG
GCCGACTATCTGGCGGCCCA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MGTEMVKLLQERHFPLASLKLLASERSAGKLLDFAGESLPVEVLRPEALKGQDIVLGATEADVARQYAGVIVEAGGVFVD
NSSAFRQDPAVPLVVPEVNLADLTAHCGIVASPNCSTILLVVAVWPLHRRRPLKRLVVSTYQAASGAGAAGMAELERQTR
QVLAGEVPTAEVFPHPIAFNLFPHNSAIGADRYCEEERKMVHETRRIFHSAALPIAVTCVRVPVLRAHSEAVNLEFEEPF
PVAEALALLREAPGLQVVEDWERNHFPMPVEASGQDAVLVGRVREDLSCPGALDLWLSGDQIRKGAALNAVQIAEQLAGG
RR

Sequences:

>Translated_322_residues
MGTEMVKLLQERHFPLASLKLLASERSAGKLLDFAGESLPVEVLRPEALKGQDIVLGATEADVARQYAGVIVEAGGVFVD
NSSAFRQDPAVPLVVPEVNLADLTAHCGIVASPNCSTILLVVAVWPLHRRRPLKRLVVSTYQAASGAGAAGMAELERQTR
QVLAGEVPTAEVFPHPIAFNLFPHNSAIGADRYCEEERKMVHETRRIFHSAALPIAVTCVRVPVLRAHSEAVNLEFEEPF
PVAEALALLREAPGLQVVEDWERNHFPMPVEASGQDAVLVGRVREDLSCPGALDLWLSGDQIRKGAALNAVQIAEQLAGG
RR
>Mature_321_residues
GTEMVKLLQERHFPLASLKLLASERSAGKLLDFAGESLPVEVLRPEALKGQDIVLGATEADVARQYAGVIVEAGGVFVDN
SSAFRQDPAVPLVVPEVNLADLTAHCGIVASPNCSTILLVVAVWPLHRRRPLKRLVVSTYQAASGAGAAGMAELERQTRQ
VLAGEVPTAEVFPHPIAFNLFPHNSAIGADRYCEEERKMVHETRRIFHSAALPIAVTCVRVPVLRAHSEAVNLEFEEPFP
VAEALALLREAPGLQVVEDWERNHFPMPVEASGQDAVLVGRVREDLSCPGALDLWLSGDQIRKGAALNAVQIAEQLAGGR
R

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=322, Percent_Identity=31.055900621118, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789841, Length=352, Percent_Identity=26.7045454545455, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320362, Length=344, Percent_Identity=28.4883720930233, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 34796; Mature: 34665

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTEMVKLLQERHFPLASLKLLASERSAGKLLDFAGESLPVEVLRPEALKGQDIVLGATE
CCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHEECCCCCCCCEEEEECCH
ADVARQYAGVIVEAGGVFVDNSSAFRQDPAVPLVVPEVNLADLTAHCGIVASPNCSTILL
HHHHHHHHCEEEECCCEEEECCCHHCCCCCCEEEECCCCHHHHHHHCCEEECCCCCCEEH
VVAVWPLHRRRPLKRLVVSTYQAASGAGAAGMAELERQTRQVLAGEVPTAEVFPHPIAFN
HHHHHCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCEEEE
LFPHNSAIGADRYCEEERKMVHETRRIFHSAALPIAVTCVRVPVLRAHSEAVNLEFEEPF
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHEEEEECCCC
PVAEALALLREAPGLQVVEDWERNHFPMPVEASGQDAVLVGRVREDLSCPGALDLWLSGD
CHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEECCH
QIRKGAALNAVQIAEQLAGGRR
HHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GTEMVKLLQERHFPLASLKLLASERSAGKLLDFAGESLPVEVLRPEALKGQDIVLGATE
CHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHEECCCCCCCCEEEEECCH
ADVARQYAGVIVEAGGVFVDNSSAFRQDPAVPLVVPEVNLADLTAHCGIVASPNCSTILL
HHHHHHHHCEEEECCCEEEECCCHHCCCCCCEEEECCCCHHHHHHHCCEEECCCCCCEEH
VVAVWPLHRRRPLKRLVVSTYQAASGAGAAGMAELERQTRQVLAGEVPTAEVFPHPIAFN
HHHHHCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCEEEE
LFPHNSAIGADRYCEEERKMVHETRRIFHSAALPIAVTCVRVPVLRAHSEAVNLEFEEPF
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHEEEEECCCC
PVAEALALLREAPGLQVVEDWERNHFPMPVEASGQDAVLVGRVREDLSCPGALDLWLSGD
CHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEECCH
QIRKGAALNAVQIAEQLAGGRR
HHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]