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The map label for this gene is bvdR

Identifier: 37520419

GI number: 37520419

Start: 900959

End: 901957

Strand: Direct

Name: bvdR

Synonym: gvip105

Alternate gene names: NA

Gene position: 900959-901957 (Clockwise)

Preceding gene: 37520417

Following gene: 37520420

Centisome position: 19.34

GC content: 66.57

Gene sequence:

>999_bases
ATGTTGCATTTCTTAATGCCTCCCTGGCCCACGGCGATCGTGGGCACGGGTTACGCAGCCCGCCAGCGGGCCATCACCCT
CTCGGGCGATCCGCGCATCAAGCTCGTCGGTTTTATCGGCCACAGCCCGGCTGCAAGCGAAAAGTTTATGGCCGAATTCG
GCATCGGGACGGGTGACGAAACGCTGCTTGCCGGGGCGCACTTGGTCTTTGTCTGCACTGTCAACCGCGACCACGGCCTC
TGGGTGCGCCGCGCCCTGGAGCAGGGTGCCCACGTCGTAGTCGAGTATCCGCTGGCGCTGGATGCTGCCGAGGGGGCGGC
GCTGATCGCCCTGGCACGCGAGCGCCGCCTGCTGTTGCATGTCGAACATATCGAGCTGATGAGCGGCATCCACCAGGCAT
TGGCCGGGCAGATGGCGGCGGTGGGTCCGGTGCATCTGGCCCGCTACAGCAATGTGGTCGCCCGCCTGCCCGAGCCGGGG
CGCTGGACCTTTTCGGTGGATCTGTTCGGTTTTCCGCTGGTGGGGGCACTCTCGCGCCTCAGCCGCCTGGTGGACCTGGT
AGGGCCGGTCGCCTCGGTCTTCTGCCAGAACCGCTACTTCGATTTGACCCCCGACGGCTACTACCGCGGCTGTTCGTGCG
TGGCGCAACTTCAATTTGAGTGCGGAGCGGTCGGACAGCTCGCCTACGCCAAAGGAGCGGGCTGCTACCAATCCGAGACC
CGCCTCGAACTGGCAGGCAGCCGGGGGGCGGTCATCCACGACGGCGAAAAGCTGCTGGTGCTGGATGGCCAGGATACCCG
CATCCTGGAGCCCGGCAGCCGCCGGGGGCTTTTCGAGCGTGACACGCGCATGGTGCTCGATGTCCTCCAAGGCAGGGGCG
AACTGTACACCACCCCCGAGCGCAGCCTGCACATTCTGGCGACAGCCGCCGCCTGCGAGCGCTCCGCCGCCCTCGGCCGC
AGCGAAGCGGTGGAAGTTCCGGCACTCCCCATAGGATAG

Upstream 100 bases:

>100_bases
CGGGAGGTATCGCTACGGTGGGAGTCCGGCGCTCCATGCCTGAGTACAAACTCCTATCCTGGAGAGGGGCTCCTCTCCAG
TCTATCGGTCACCACTACCT

Downstream 100 bases:

>100_bases
AAACAGCACGCCCAGGGTGGTCCATGGCCTTGCAGATCTACAACACGCTCACGCGCCGCAAAGAACCGTTCGTCCCCCTC
GAAGCGGGCACAGTCAAAAT

Product: biliverdin reductase

Products: biliverdin; NADH; NADPH; H+

Alternate protein names: Oxidoreductase Domain-Containing Protein; Oxidoreductase Domain Protein; Oxidoreductase-Like; Oxidoreductase Biliverdin Reductase; Homoserine Dehydrogenase

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLHFLMPPWPTAIVGTGYAARQRAITLSGDPRIKLVGFIGHSPAASEKFMAEFGIGTGDETLLAGAHLVFVCTVNRDHGL
WVRRALEQGAHVVVEYPLALDAAEGAALIALARERRLLLHVEHIELMSGIHQALAGQMAAVGPVHLARYSNVVARLPEPG
RWTFSVDLFGFPLVGALSRLSRLVDLVGPVASVFCQNRYFDLTPDGYYRGCSCVAQLQFECGAVGQLAYAKGAGCYQSET
RLELAGSRGAVIHDGEKLLVLDGQDTRILEPGSRRGLFERDTRMVLDVLQGRGELYTTPERSLHILATAAACERSAALGR
SEAVEVPALPIG

Sequences:

>Translated_332_residues
MLHFLMPPWPTAIVGTGYAARQRAITLSGDPRIKLVGFIGHSPAASEKFMAEFGIGTGDETLLAGAHLVFVCTVNRDHGL
WVRRALEQGAHVVVEYPLALDAAEGAALIALARERRLLLHVEHIELMSGIHQALAGQMAAVGPVHLARYSNVVARLPEPG
RWTFSVDLFGFPLVGALSRLSRLVDLVGPVASVFCQNRYFDLTPDGYYRGCSCVAQLQFECGAVGQLAYAKGAGCYQSET
RLELAGSRGAVIHDGEKLLVLDGQDTRILEPGSRRGLFERDTRMVLDVLQGRGELYTTPERSLHILATAAACERSAALGR
SEAVEVPALPIG
>Mature_332_residues
MLHFLMPPWPTAIVGTGYAARQRAITLSGDPRIKLVGFIGHSPAASEKFMAEFGIGTGDETLLAGAHLVFVCTVNRDHGL
WVRRALEQGAHVVVEYPLALDAAEGAALIALARERRLLLHVEHIELMSGIHQALAGQMAAVGPVHLARYSNVVARLPEPG
RWTFSVDLFGFPLVGALSRLSRLVDLVGPVASVFCQNRYFDLTPDGYYRGCSCVAQLQFECGAVGQLAYAKGAGCYQSET
RLELAGSRGAVIHDGEKLLVLDGQDTRILEPGSRRGLFERDTRMVLDVLQGRGELYTTPERSLHILATAAACERSAALGR
SEAVEVPALPIG

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.3.1.24

Molecular weight: Translated: 35792; Mature: 35792

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHFLMPPWPTAIVGTGYAARQRAITLSGDPRIKLVGFIGHSPAASEKFMAEFGIGTGDE
CCCCCCCCCCCCEEECCCHHHCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
TLLAGAHLVFVCTVNRDHGLWVRRALEQGAHVVVEYPLALDAAEGAALIALARERRLLLH
HHEECCEEEEEEEECCCCCHHHHHHHHCCCEEEEEECEEEECCCCCEEEEEHHCCEEEEE
VEHIELMSGIHQALAGQMAAVGPVHLARYSNVVARLPEPGRWTFSVDLFGFPLVGALSRL
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
SRLVDLVGPVASVFCQNRYFDLTPDGYYRGCSCVAQLQFECGAVGQLAYAKGAGCYQSET
HHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHEEEECCCCCCCCCHHHCCCCCCCCCC
RLELAGSRGAVIHDGEKLLVLDGQDTRILEPGSRRGLFERDTRMVLDVLQGRGELYTTPE
EEEECCCCCCEEECCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCC
RSLHILATAAACERSAALGRSEAVEVPALPIG
CCEEEEEEHHHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure
MLHFLMPPWPTAIVGTGYAARQRAITLSGDPRIKLVGFIGHSPAASEKFMAEFGIGTGDE
CCCCCCCCCCCCEEECCCHHHCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCC
TLLAGAHLVFVCTVNRDHGLWVRRALEQGAHVVVEYPLALDAAEGAALIALARERRLLLH
HHEECCEEEEEEEECCCCCHHHHHHHHCCCEEEEEECEEEECCCCCEEEEEHHCCEEEEE
VEHIELMSGIHQALAGQMAAVGPVHLARYSNVVARLPEPGRWTFSVDLFGFPLVGALSRL
HHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHH
SRLVDLVGPVASVFCQNRYFDLTPDGYYRGCSCVAQLQFECGAVGQLAYAKGAGCYQSET
HHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHEEEECCCCCCCCCHHHCCCCCCCCCC
RLELAGSRGAVIHDGEKLLVLDGQDTRILEPGSRRGLFERDTRMVLDVLQGRGELYTTPE
EEEECCCCCCEEECCCEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCC
RSLHILATAAACERSAALGRSEAVEVPALPIG
CCEEEEEEHHHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: bilirubin; NAD+; NADP+

Specific reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA