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The map label for this gene is fur [H]

Identifier: 37520352

GI number: 37520352

Start: 835549

End: 835950

Strand: Direct

Name: fur [H]

Synonym: glr0783

Alternate gene names: 37520352

Gene position: 835549-835950 (Clockwise)

Preceding gene: 37520351

Following gene: 37520353

Centisome position: 17.93

GC content: 58.21

Gene sequence:

>402_bases
ATGCCCGCGAGAAAGCTGACCAAAGGGCAGCAGGCGGTGCTCGAAGCCCTTGCCAGTTCAAAGCGCCCCCTTTGTGCTCA
AGATATCTACCTGCAACTGCGCGGGACCGAGCAGGAAGTGGGTCTTGCCACGGTTTACCGCTCGCTCGAAGCGTTGCTCG
CGGACGACCGCATTCAGATCATCGACGTGCGCGACAACCAGGCCCATTATTTGATGGGGCGCGCCAACCATAGCCAGCAC
CATCTTATTTGTCTGAGCTGCAAACGGGTGGTTCCCCTCGATCACTGCCCGGTGAGTGCTCTCGAACAACACCTTTCCCA
GGATCACGAGTTTCAGATTGCTTACCATGTGCTCGATTTTTACGGCACCTGCGGCGAGTGCCGTCAGGCTGTGGGAGCCT
GA

Upstream 100 bases:

>100_bases
ATGTCCGATCAGCTCAACACCTTCGGCATGACGCCCCAACAGATGTTCCAGCAGATGGAATCAACCCTCGAACAGATGAA
AGCCCAGATTAAGGAATGAC

Downstream 100 bases:

>100_bases
AGCGCACGATGTCTTCTATTGCGATTGTCTGGCACCGTCGGGATCTCAGAGTGCACGACAACCCTGCTCTCTGGCAGGCA
AGCCGCACGGGCGGGCAGGT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPARKLTKGQQAVLEALASSKRPLCAQDIYLQLRGTEQEVGLATVYRSLEALLADDRIQIIDVRDNQAHYLMGRANHSQH
HLICLSCKRVVPLDHCPVSALEQHLSQDHEFQIAYHVLDFYGTCGECRQAVGA

Sequences:

>Translated_133_residues
MPARKLTKGQQAVLEALASSKRPLCAQDIYLQLRGTEQEVGLATVYRSLEALLADDRIQIIDVRDNQAHYLMGRANHSQH
HLICLSCKRVVPLDHCPVSALEQHLSQDHEFQIAYHVLDFYGTCGECRQAVGA
>Mature_132_residues
PARKLTKGQQAVLEALASSKRPLCAQDIYLQLRGTEQEVGLATVYRSLEALLADDRIQIIDVRDNQAHYLMGRANHSQHH
LICLSCKRVVPLDHCPVSALEQHLSQDHEFQIAYHVLDFYGTCGECRQAVGA

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 14907; Mature: 14776

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARKLTKGQQAVLEALASSKRPLCAQDIYLQLRGTEQEVGLATVYRSLEALLADDRIQI
CCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEE
IDVRDNQAHYLMGRANHSQHHLICLSCKRVVPLDHCPVSALEQHLSQDHEFQIAYHVLDF
EEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
YGTCGECRQAVGA
HCCHHHHHHHHCC
>Mature Secondary Structure 
PARKLTKGQQAVLEALASSKRPLCAQDIYLQLRGTEQEVGLATVYRSLEALLADDRIQI
CCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEE
IDVRDNQAHYLMGRANHSQHHLICLSCKRVVPLDHCPVSALEQHLSQDHEFQIAYHVLDF
EEECCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
YGTCGECRQAVGA
HCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]