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The map label for this gene is trpE [H]

Identifier: 37520326

GI number: 37520326

Start: 807567

End: 808925

Strand: Reverse

Name: trpE [H]

Synonym: gvip086

Alternate gene names: 37520326

Gene position: 808925-807567 (Counterclockwise)

Preceding gene: 37520329

Following gene: 37520325

Centisome position: 17.36

GC content: 64.75

Gene sequence:

>1359_bases
ATGTCGATGGTTGCCCCCACCTGGCACTGGCTGTACCTTCCCCTCGAAGGACGCACCGGCTCGTGCCTGTTTGAGCGCCT
GTTCGGCGAGGAGGCGGTGGCGGTCCTGCTCGAAAGCCCCCAACTCTCGCCGCGTACCGCCCGCTACTCGATCTTGGCTG
CCTGTCCGCGGCGCGTGCTTGCTCCCGCCGTCGGTGAGATTCTGCCCGCGCTGCGCGCTTGGCTTGCCGCCGCGCGGCGG
CAGCTGCCGCCGCCCGAGTGGAGGGGGCTGCCCTTTCGCGGCGGGCTTGTGGGCTGGTTCGGCTACGACCTGGCCTGGGA
AATCGAAAGGCTGCCGTGGCTGCGGAACGACCCCTTGCCTTTTCCGACGGCCTGGTGGTTTGAGCCGGCCGTCTTTGCCG
TCGCCGATCATCGCGAGGATAAGCTTTTGCTCGCCGTCGACAATCGGTCGGGACTCGGTCCCGACCGGGGAAGCCTGGCG
TACTGGTGCAAGCGGCTCGACAGACCGATTTTGACCGACGAGGAGATCAACAGTGGTGCGTTGCCGCGCCTGACGTCGCG
CGACAGGTTTTTGGAGGCTGTCCATCAGGTCAAGGAGCACATTGCGGCCGGGGATATCTTTCAGTGCAACCTCTCGCTTC
GCTTCGAACTCGACTGGGAAGGCAATGGCTGGCGGCTCTACCGACGGCTGGTCGGGCTCAATCCTTCGCCTTTCGCCTGT
TACTGGCGCACGCCCTTCGGCGAAATCGTCAGCTGCTCGCCCGAGCGGCTTTTAGAAGTGCGCGGCGAAGCGCTGAGCAC
CCGCCCGATCGCGGGAACGCGCCCGCGCGGGTTCACCGCTGCCGCCGATCAACGCCTGGAAAGCGAACTGTTAATCAGTC
CCAAGGAACGCGCCGAGCACATCATGCTGGTCGATCTCGAACGCAACGATCTCGGGCGGGTCTCACAACCGGGCAGCGTG
CAGGTGGACGAACTGATGGTCATCGAGCGCTACTCCCACGTCATGCACATTGTCTCCAACGTCGTCGGCCGCCTGCAGCC
CGGATGCGACGCCCTGGACGCGGTGCGCGCCGTCTATCCCGGCGGCACGATCACCGGCTGTCCGAAGGTGCGCTGCATGG
AAATTATCGAGAGGCTCGAACCGGTGCGCCGCTCGCTTTTTTACGGCTCGGCGGGTTACCTCGACTGCACCGGTGACCTG
GATCTCAACATTTTGATCCGCACGCTGCTCAAGTCCGGCTCCCGGATTTGGGGGCAAGTCGGGGCGGGCATCGTCGCCGA
TTCTGATCCCCAGGGCGAATACCTCGAATCGCTCGCCAAGGCCAAAGCCCTCTGGAAAGCCCTGGGAGACAGTCGATAA

Upstream 100 bases:

>100_bases
GCGCAATCGCAGACTGCTCTCACTTTGACATATGCGCCTGGGTTTGGCACACCATCGCAGGCGGGCGAAAATGACCCCAG
TCCTTGACGCTTTGCTGTCG

Downstream 100 bases:

>100_bases
GTTGAGCGGCAAATCGATCTAAAAAAATTCATAGTAAATGTACCCAAACCGCCCCCGATGTTTTTTACTGGGTACATACG
GACCGATGTAGTCAGCAAGA

Product: anthranilate synthase component I-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSMVAPTWHWLYLPLEGRTGSCLFERLFGEEAVAVLLESPQLSPRTARYSILAACPRRVLAPAVGEILPALRAWLAAARR
QLPPPEWRGLPFRGGLVGWFGYDLAWEIERLPWLRNDPLPFPTAWWFEPAVFAVADHREDKLLLAVDNRSGLGPDRGSLA
YWCKRLDRPILTDEEINSGALPRLTSRDRFLEAVHQVKEHIAAGDIFQCNLSLRFELDWEGNGWRLYRRLVGLNPSPFAC
YWRTPFGEIVSCSPERLLEVRGEALSTRPIAGTRPRGFTAAADQRLESELLISPKERAEHIMLVDLERNDLGRVSQPGSV
QVDELMVIERYSHVMHIVSNVVGRLQPGCDALDAVRAVYPGGTITGCPKVRCMEIIERLEPVRRSLFYGSAGYLDCTGDL
DLNILIRTLLKSGSRIWGQVGAGIVADSDPQGEYLESLAKAKALWKALGDSR

Sequences:

>Translated_452_residues
MSMVAPTWHWLYLPLEGRTGSCLFERLFGEEAVAVLLESPQLSPRTARYSILAACPRRVLAPAVGEILPALRAWLAAARR
QLPPPEWRGLPFRGGLVGWFGYDLAWEIERLPWLRNDPLPFPTAWWFEPAVFAVADHREDKLLLAVDNRSGLGPDRGSLA
YWCKRLDRPILTDEEINSGALPRLTSRDRFLEAVHQVKEHIAAGDIFQCNLSLRFELDWEGNGWRLYRRLVGLNPSPFAC
YWRTPFGEIVSCSPERLLEVRGEALSTRPIAGTRPRGFTAAADQRLESELLISPKERAEHIMLVDLERNDLGRVSQPGSV
QVDELMVIERYSHVMHIVSNVVGRLQPGCDALDAVRAVYPGGTITGCPKVRCMEIIERLEPVRRSLFYGSAGYLDCTGDL
DLNILIRTLLKSGSRIWGQVGAGIVADSDPQGEYLESLAKAKALWKALGDSR
>Mature_451_residues
SMVAPTWHWLYLPLEGRTGSCLFERLFGEEAVAVLLESPQLSPRTARYSILAACPRRVLAPAVGEILPALRAWLAAARRQ
LPPPEWRGLPFRGGLVGWFGYDLAWEIERLPWLRNDPLPFPTAWWFEPAVFAVADHREDKLLLAVDNRSGLGPDRGSLAY
WCKRLDRPILTDEEINSGALPRLTSRDRFLEAVHQVKEHIAAGDIFQCNLSLRFELDWEGNGWRLYRRLVGLNPSPFACY
WRTPFGEIVSCSPERLLEVRGEALSTRPIAGTRPRGFTAAADQRLESELLISPKERAEHIMLVDLERNDLGRVSQPGSVQ
VDELMVIERYSHVMHIVSNVVGRLQPGCDALDAVRAVYPGGTITGCPKVRCMEIIERLEPVRRSLFYGSAGYLDCTGDLD
LNILIRTLLKSGSRIWGQVGAGIVADSDPQGEYLESLAKAKALWKALGDSR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=370, Percent_Identity=37.5675675675676, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1787518, Length=383, Percent_Identity=36.2924281984334, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786809, Length=227, Percent_Identity=27.3127753303965, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082077, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=32.3462414578588, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=398, Percent_Identity=24.8743718592965, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 50671; Mature: 50540

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMVAPTWHWLYLPLEGRTGSCLFERLFGEEAVAVLLESPQLSPRTARYSILAACPRRVL
CCCCCCCEEEEEEEECCCCHHHHHHHHHCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHH
APAVGEILPALRAWLAAARRQLPPPEWRGLPFRGGLVGWFGYDLAWEIERLPWLRNDPLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCC
FPTAWWFEPAVFAVADHREDKLLLAVDNRSGLGPDRGSLAYWCKRLDRPILTDEEINSGA
CCCCHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LPRLTSRDRFLEAVHQVKEHIAAGDIFQCNLSLRFELDWEGNGWRLYRRLVGLNPSPFAC
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCEEE
YWRTPFGEIVSCSPERLLEVRGEALSTRPIAGTRPRGFTAAADQRLESELLISPKERAEH
EEECCCHHHHCCCHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCE
IMLVDLERNDLGRVSQPGSVQVDELMVIERYSHVMHIVSNVVGRLQPGCDALDAVRAVYP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GGTITGCPKVRCMEIIERLEPVRRSLFYGSAGYLDCTGDLDLNILIRTLLKSGSRIWGQV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHH
GAGIVADSDPQGEYLESLAKAKALWKALGDSR
CCCCEECCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMVAPTWHWLYLPLEGRTGSCLFERLFGEEAVAVLLESPQLSPRTARYSILAACPRRVL
CCCCCCEEEEEEEECCCCHHHHHHHHHCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHH
APAVGEILPALRAWLAAARRQLPPPEWRGLPFRGGLVGWFGYDLAWEIERLPWLRNDPLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEHHHHCCCCCCCCCC
FPTAWWFEPAVFAVADHREDKLLLAVDNRSGLGPDRGSLAYWCKRLDRPILTDEEINSGA
CCCCHHHCCEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
LPRLTSRDRFLEAVHQVKEHIAAGDIFQCNLSLRFELDWEGNGWRLYRRLVGLNPSPFAC
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCCEEE
YWRTPFGEIVSCSPERLLEVRGEALSTRPIAGTRPRGFTAAADQRLESELLISPKERAEH
EEECCCHHHHCCCHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCE
IMLVDLERNDLGRVSQPGSVQVDELMVIERYSHVMHIVSNVVGRLQPGCDALDAVRAVYP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GGTITGCPKVRCMEIIERLEPVRRSLFYGSAGYLDCTGDLDLNILIRTLLKSGSRIWGQV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCHHHHHH
GAGIVADSDPQGEYLESLAKAKALWKALGDSR
CCCCEECCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]