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The map label for this gene is gpmI

Identifier: 37520325

GI number: 37520325

Start: 805817

End: 807427

Strand: Reverse

Name: gpmI

Synonym: gll0756

Alternate gene names: 37520325

Gene position: 807427-805817 (Counterclockwise)

Preceding gene: 37520326

Following gene: 37520323

Centisome position: 17.33

GC content: 64.74

Gene sequence:

>1611_bases
ATGGCATTTATGGGCACTTCTAGCGCAGTCCATCCAGCGATTCTGGTCATCCTCGACGGTTGGGGCTACCGCGAGCAGAC
CGACGGCAACGCCGTCGCCGCCGCCAAAACTCCGATCTTCGACGCGCTCAAAGCCAGCTATCCTTTTACACTCATCCACA
CCAGCGGCAAGGCGGTCGGTCTGCCGCGCGGGCAGATGGGCAACTCCGAAGTCGGCCACCTCAACCTGGGTGCGGGCCGG
ATGGTCCCCCAGGAGCTCGTGCGCATCTCCGACGCGGTCGAAGAAGGCACGCTGCTTTCCAACCCCGAACTGCTGCGTCT
CTGCCGCACGGTGCGCGAGCGGGGCGGCAAGCTGCATGGGGTGGGCCTCGTCTCCGACGGCGGTGTCCACTCCCACATCG
AGCATCTGTTTGGGCTATTGGACCTTGCCAAGCGGGAGGGTTTTGAAACGCTGTTTATCCACGGGATGAGTGACGGTCGT
GACACTCCTCCCACTTCGGGTGTTGCGTACTTCGAGAAGCTCGAAGCCCGCATCGCCGAAACGGGCTTCGGCACGATTGC
TACTCTGGGTGGCCGTTACTTTGGGATGGACCGCGATCGCCGCTGGGATCGCACCGAGGCGATGTACCGGGTGATGACCG
AGACCGGCCCCGGCACGGGTAAACGCGCCTCCGAGACCTTGCGCGAGAGCCACGCCGCCGGCAAGACCGACGAATTCGTA
TTGCCGGTGCGCCTGGCTGCCGGTGCGGTCGAACCCGGTGATGGGGTGATCTACTTCAACTTCCGCCCCGACCGGGCGCG
CCAGCTCACCCGCGCCTTCGTGCAGGCGGACTTCGACGGTTTCGTGCGCCCCTACCTCGACCCGCTCGCCTTTCTCACCT
TCACCCAGTACGACGCAACCTTGCCGGTGGCAGTGGCTTTTGCGCCCCAGAGCCTCGACAACCTCCTGGGTCAGGTGATT
GCCCACCATGGCCTGCGGCAGTTCCGCATCGCCGAGACCGAGAAGTACGCCCACGTCACCTATTTCTTTAACGGCGGCAT
CGAGACGCCCCTGCCCGGCGAGGAGCGCTCGATGATCCAGAGCCCCCTGGTGCCCACTTACGATCTGAAGCCCGAGATGG
CCGCCCGCGAGGTCACCGACCACGCCGTCGCCGCCATCGAAACGCGCCAGTACTCGCTGATTGTGATCAACTACGCCAAC
CCGGACATGGTGGGCCATACCGGCAACTTCGACGCTACGGTTAAGGCGGTCGAGACGGTGGACGCCTGTATCGGCCGCCT
GGTGGAGGCGTGCGTGCGCGCCGGGGGCACAATGCTGCTCACCGCCGACCACGGCAACGCCGAACTGATGTGGGACGAAC
AGGGCAATCCCTGGACCGCCCACACCACCAACCCGGTGCCGTTTATTTTGATCGAGAGCGAGGGTCTTAAAATTCCCGGT
TGGGGAACGGACGTGCAGTTGCGCGCCGGGGGCAGCCTCGGCGACATTGCCCCGACGATCCTCGAAATTTTGGGCCTCCC
GCAGCCCGCCGAGATGACCGGCCGCTCGCTGTTGGGCGAAAGTGAAATCGAGATCCGCACCCCCCGCAGCCCTCTGCGCG
TGGGGCTGTGA

Upstream 100 bases:

>100_bases
GTACCCAAACCGCCCCCGATGTTTTTTACTGGGTACATACGGACCGATGTAGTCAGCAAGACTCCCTATAAAAAATAGGG
AGTCTGCACCATTTAGGGTC

Downstream 100 bases:

>100_bases
GAACATAACCCGCATCCAGAATCTCGGCTTTACTCGGCGGATTCTAGAAGTGAATTTGCTTCAGAACACTGGTCACATCG
CCGCTTCAGGAACTGGCGAT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MAFMGTSSAVHPAILVILDGWGYREQTDGNAVAAAKTPIFDALKASYPFTLIHTSGKAVGLPRGQMGNSEVGHLNLGAGR
MVPQELVRISDAVEEGTLLSNPELLRLCRTVRERGGKLHGVGLVSDGGVHSHIEHLFGLLDLAKREGFETLFIHGMSDGR
DTPPTSGVAYFEKLEARIAETGFGTIATLGGRYFGMDRDRRWDRTEAMYRVMTETGPGTGKRASETLRESHAAGKTDEFV
LPVRLAAGAVEPGDGVIYFNFRPDRARQLTRAFVQADFDGFVRPYLDPLAFLTFTQYDATLPVAVAFAPQSLDNLLGQVI
AHHGLRQFRIAETEKYAHVTYFFNGGIETPLPGEERSMIQSPLVPTYDLKPEMAAREVTDHAVAAIETRQYSLIVINYAN
PDMVGHTGNFDATVKAVETVDACIGRLVEACVRAGGTMLLTADHGNAELMWDEQGNPWTAHTTNPVPFILIESEGLKIPG
WGTDVQLRAGGSLGDIAPTILEILGLPQPAEMTGRSLLGESEIEIRTPRSPLRVGL

Sequences:

>Translated_536_residues
MAFMGTSSAVHPAILVILDGWGYREQTDGNAVAAAKTPIFDALKASYPFTLIHTSGKAVGLPRGQMGNSEVGHLNLGAGR
MVPQELVRISDAVEEGTLLSNPELLRLCRTVRERGGKLHGVGLVSDGGVHSHIEHLFGLLDLAKREGFETLFIHGMSDGR
DTPPTSGVAYFEKLEARIAETGFGTIATLGGRYFGMDRDRRWDRTEAMYRVMTETGPGTGKRASETLRESHAAGKTDEFV
LPVRLAAGAVEPGDGVIYFNFRPDRARQLTRAFVQADFDGFVRPYLDPLAFLTFTQYDATLPVAVAFAPQSLDNLLGQVI
AHHGLRQFRIAETEKYAHVTYFFNGGIETPLPGEERSMIQSPLVPTYDLKPEMAAREVTDHAVAAIETRQYSLIVINYAN
PDMVGHTGNFDATVKAVETVDACIGRLVEACVRAGGTMLLTADHGNAELMWDEQGNPWTAHTTNPVPFILIESEGLKIPG
WGTDVQLRAGGSLGDIAPTILEILGLPQPAEMTGRSLLGESEIEIRTPRSPLRVGL
>Mature_535_residues
AFMGTSSAVHPAILVILDGWGYREQTDGNAVAAAKTPIFDALKASYPFTLIHTSGKAVGLPRGQMGNSEVGHLNLGAGRM
VPQELVRISDAVEEGTLLSNPELLRLCRTVRERGGKLHGVGLVSDGGVHSHIEHLFGLLDLAKREGFETLFIHGMSDGRD
TPPTSGVAYFEKLEARIAETGFGTIATLGGRYFGMDRDRRWDRTEAMYRVMTETGPGTGKRASETLRESHAAGKTDEFVL
PVRLAAGAVEPGDGVIYFNFRPDRARQLTRAFVQADFDGFVRPYLDPLAFLTFTQYDATLPVAVAFAPQSLDNLLGQVIA
HHGLRQFRIAETEKYAHVTYFFNGGIETPLPGEERSMIQSPLVPTYDLKPEMAAREVTDHAVAAIETRQYSLIVINYANP
DMVGHTGNFDATVKAVETVDACIGRLVEACVRAGGTMLLTADHGNAELMWDEQGNPWTAHTTNPVPFILIESEGLKIPGW
GTDVQLRAGGSLGDIAPTILEILGLPQPAEMTGRSLLGESEIEIRTPRSPLRVGL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=514, Percent_Identity=47.0817120622568, Blast_Score=474, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI32564249, Length=527, Percent_Identity=44.022770398482, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17507741, Length=527, Percent_Identity=44.022770398482, Blast_Score=426, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_GLOVI (Q7NMK9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923702.1
- ProteinModelPortal:   Q7NMK9
- SMR:   Q7NMK9
- GeneID:   2599375
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll0756
- NMPDR:   fig|251221.1.peg.756
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   GVIO251221:GLL0756-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 58204; Mature: 58073

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: ACT_SITE 69-69

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFMGTSSAVHPAILVILDGWGYREQTDGNAVAAAKTPIFDALKASYPFTLIHTSGKAVG
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHCCCCEEEEEECCCEEC
LPRGQMGNSEVGHLNLGAGRMVPQELVRISDAVEEGTLLSNPELLRLCRTVRERGGKLHG
CCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEE
VGLVSDGGVHSHIEHLFGLLDLAKREGFETLFIHGMSDGRDTPPTSGVAYFEKLEARIAE
EEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TGFGTIATLGGRYFGMDRDRRWDRTEAMYRVMTETGPGTGKRASETLRESHAAGKTDEFV
CCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEE
LPVRLAAGAVEPGDGVIYFNFRPDRARQLTRAFVQADFDGFVRPYLDPLAFLTFTQYDAT
EEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC
LPVAVAFAPQSLDNLLGQVIAHHGLRQFRIAETEKYAHVTYFFNGGIETPLPGEERSMIQ
CCEEEEECHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHH
SPLVPTYDLKPEMAAREVTDHAVAAIETRQYSLIVINYANPDMVGHTGNFDATVKAVETV
CCCCCCCCCCCCHHHHHHHHHHHEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
DACIGRLVEACVRAGGTMLLTADHGNAELMWDEQGNPWTAHTTNPVPFILIESEGLKIPG
HHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEECCCCEEEEEECCCCEECCC
WGTDVQLRAGGSLGDIAPTILEILGLPQPAEMTGRSLLGESEIEIRTPRSPLRVGL
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
AFMGTSSAVHPAILVILDGWGYREQTDGNAVAAAKTPIFDALKASYPFTLIHTSGKAVG
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHCCCCEEEEEECCCEEC
LPRGQMGNSEVGHLNLGAGRMVPQELVRISDAVEEGTLLSNPELLRLCRTVRERGGKLHG
CCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEE
VGLVSDGGVHSHIEHLFGLLDLAKREGFETLFIHGMSDGRDTPPTSGVAYFEKLEARIAE
EEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
TGFGTIATLGGRYFGMDRDRRWDRTEAMYRVMTETGPGTGKRASETLRESHAAGKTDEFV
CCCCHHHHCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEE
LPVRLAAGAVEPGDGVIYFNFRPDRARQLTRAFVQADFDGFVRPYLDPLAFLTFTQYDAT
EEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCC
LPVAVAFAPQSLDNLLGQVIAHHGLRQFRIAETEKYAHVTYFFNGGIETPLPGEERSMIQ
CCEEEEECHHHHHHHHHHHHHHCCCHHEEEECCCCEEEEEEEEECCCCCCCCCHHHHHHH
SPLVPTYDLKPEMAAREVTDHAVAAIETRQYSLIVINYANPDMVGHTGNFDATVKAVETV
CCCCCCCCCCCCHHHHHHHHHHHEEEEECCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
DACIGRLVEACVRAGGTMLLTADHGNAELMWDEQGNPWTAHTTNPVPFILIESEGLKIPG
HHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEECCCCEEEEEECCCCEECCC
WGTDVQLRAGGSLGDIAPTILEILGLPQPAEMTGRSLLGESEIEIRTPRSPLRVGL
CCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292