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The map label for this gene is wecB [C]

Identifier: 37520270

GI number: 37520270

Start: 747151

End: 748320

Strand: Direct

Name: wecB [C]

Synonym: glr0701

Alternate gene names: 37520270

Gene position: 747151-748320 (Clockwise)

Preceding gene: 37520267

Following gene: 37520271

Centisome position: 16.04

GC content: 67.01

Gene sequence:

>1170_bases
GTGCAATACCTGGATCGAACGAGGGAAGGTGCCCGCCTGGAGGGTTACACTGTCGCCATGAGCAAAGTTGCCATTGTCCT
GGGAACCCGGCCGGAGGCGGTGAAACTGGCCCCGGTGATCCTGGGCTTTCGAAACTGTCCGCACCTGCACACCCGGGTGA
TCCTCACCGGCCAACACCGGGAGATGCTCTACCAGACCCTGGCTTGGTTCGGGATCGAGGCGGACGCCGACTTGCAGATT
ATGACGCCGCGCCAGAGCCTGGCCGACATTACCTGTCGGGCGCTGGTGGGCCTCGAAGCCGTCCTCACCGACGAACGCCC
CGACCTGGTGCTGGTGCAGGGAGACACCACGACCACCTTCGCCGCCGCCCTCGCCGCCTTCTACCAAAAAATTGCCCTGG
GCCACGTCGAAGCGGGCCTGCGCACAGGGGTCGCAGACGACCCGTACCCCGAGGAGATGAACCGCCGCCTCACCTCGCGC
CTGGCAGCCCTGCACTTTGCCCCGACGATGCGCGCGGCGGAGAACCTCAAGCGCGAAGGCATCCTCGATCACGTCTATCT
CACCGGCAACACCGTGATCGACGCGCTGCACACCATCGCCAGCCGCAAGCCCGAGTGCCCGGTGGCGGGCCTCGACTGGG
AAAAGTCGCGGGTGATGCTGGTCACCGCCCACCGCCGCGAGAACTGGGGCCAACCGCTCGAAAACATCGCCCACGCCCTG
ATCGATATTCTCGAAGCGCACCCGGACACCGCCCTGGTGCTGCCTTTGCACAAAAATCCGACCGTGCGCGAACCGCTCCA
GGGCATCCTCGGTGCGCACCCGCGCGCCTTTTTGGACGAACCGTTCGACTACCCGCAGCTGGTGGGTGCCCTGCAGCGCT
CCACCCTGGTCCTCACCGACTCGGGCGGACTGCAGGAGGAGGCGCCCGCCTTCGGCAAACCCGTGCTGGTGCTGCGCGAG
ACCACCGAGCGGCCCGAGGCGATCGAGGCGGGGGTAGCCCTCAAAGTCGGCACCGACCGCACCGCCATCGCCCGGGCCGC
CCACGCTCTGCTCACCGACGATGCCCTCTATGGGCAGATGGCCCGGGCGGTCAACCCCTTCGGCGACGGCCACGCGACCG
GGCGCATTTTGCGCTCGACCCTTGCCTTTTTGGGGTTGCCCTCAGATTGA

Upstream 100 bases:

>100_bases
GGAACGACAACAGAAATCGACTGAGGCATCGCTATATCTTAATTGGGAAGCGCCGTCGGGGCCGCTCACAAAGCTTCAAT
CAGCTTACAACGGCGCATAG

Downstream 100 bases:

>100_bases
CGGGCCGCGGATCGACCCGCATCGATGCGATGGCCAGTCCAGATATGTGGTGTTTCAGCGGGCAAATAGCCGCTTTTCTG
AGGTCGGCCCCCCAGATGTA

Product: UDP-N-acetyl glucosamine-2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MQYLDRTREGARLEGYTVAMSKVAIVLGTRPEAVKLAPVILGFRNCPHLHTRVILTGQHREMLYQTLAWFGIEADADLQI
MTPRQSLADITCRALVGLEAVLTDERPDLVLVQGDTTTTFAAALAAFYQKIALGHVEAGLRTGVADDPYPEEMNRRLTSR
LAALHFAPTMRAAENLKREGILDHVYLTGNTVIDALHTIASRKPECPVAGLDWEKSRVMLVTAHRRENWGQPLENIAHAL
IDILEAHPDTALVLPLHKNPTVREPLQGILGAHPRAFLDEPFDYPQLVGALQRSTLVLTDSGGLQEEAPAFGKPVLVLRE
TTERPEAIEAGVALKVGTDRTAIARAAHALLTDDALYGQMARAVNPFGDGHATGRILRSTLAFLGLPSD

Sequences:

>Translated_389_residues
MQYLDRTREGARLEGYTVAMSKVAIVLGTRPEAVKLAPVILGFRNCPHLHTRVILTGQHREMLYQTLAWFGIEADADLQI
MTPRQSLADITCRALVGLEAVLTDERPDLVLVQGDTTTTFAAALAAFYQKIALGHVEAGLRTGVADDPYPEEMNRRLTSR
LAALHFAPTMRAAENLKREGILDHVYLTGNTVIDALHTIASRKPECPVAGLDWEKSRVMLVTAHRRENWGQPLENIAHAL
IDILEAHPDTALVLPLHKNPTVREPLQGILGAHPRAFLDEPFDYPQLVGALQRSTLVLTDSGGLQEEAPAFGKPVLVLRE
TTERPEAIEAGVALKVGTDRTAIARAAHALLTDDALYGQMARAVNPFGDGHATGRILRSTLAFLGLPSD
>Mature_389_residues
MQYLDRTREGARLEGYTVAMSKVAIVLGTRPEAVKLAPVILGFRNCPHLHTRVILTGQHREMLYQTLAWFGIEADADLQI
MTPRQSLADITCRALVGLEAVLTDERPDLVLVQGDTTTTFAAALAAFYQKIALGHVEAGLRTGVADDPYPEEMNRRLTSR
LAALHFAPTMRAAENLKREGILDHVYLTGNTVIDALHTIASRKPECPVAGLDWEKSRVMLVTAHRRENWGQPLENIAHAL
IDILEAHPDTALVLPLHKNPTVREPLQGILGAHPRAFLDEPFDYPQLVGALQRSTLVLTDSGGLQEEAPAFGKPVLVLRE
TTERPEAIEAGVALKVGTDRTAIARAAHALLTDDALYGQMARAVNPFGDGHATGRILRSTLAFLGLPSD

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=368, Percent_Identity=50.2717391304348, Blast_Score=330, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 42499; Mature: 42499

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLDRTREGARLEGYTVAMSKVAIVLGTRPEAVKLAPVILGFRNCPHLHTRVILTGQHR
CCCHHHCCCCCCCCCEEEEEEEEEEEECCCCCCEEHHHHHHCCCCCCCCEEEEEEECCHH
EMLYQTLAWFGIEADADLQIMTPRQSLADITCRALVGLEAVLTDERPDLVLVQGDTTTTF
HHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHH
AAALAAFYQKIALGHVEAGLRTGVADDPYPEEMNRRLTSRLAALHFAPTMRAAENLKREG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILDHVYLTGNTVIDALHTIASRKPECPVAGLDWEKSRVMLVTAHRRENWGQPLENIAHAL
CEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHH
IDILEAHPDTALVLPLHKNPTVREPLQGILGAHPRAFLDEPFDYPQLVGALQRSTLVLTD
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCEEEEEC
SGGLQEEAPAFGKPVLVLRETTERPEAIEAGVALKVGTDRTAIARAAHALLTDDALYGQM
CCCCCCCCCCCCCCEEEEECCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
ARAVNPFGDGHATGRILRSTLAFLGLPSD
HHHCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQYLDRTREGARLEGYTVAMSKVAIVLGTRPEAVKLAPVILGFRNCPHLHTRVILTGQHR
CCCHHHCCCCCCCCCEEEEEEEEEEEECCCCCCEEHHHHHHCCCCCCCCEEEEEEECCHH
EMLYQTLAWFGIEADADLQIMTPRQSLADITCRALVGLEAVLTDERPDLVLVQGDTTTTF
HHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCHHHH
AAALAAFYQKIALGHVEAGLRTGVADDPYPEEMNRRLTSRLAALHFAPTMRAAENLKREG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ILDHVYLTGNTVIDALHTIASRKPECPVAGLDWEKSRVMLVTAHRRENWGQPLENIAHAL
CEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHH
IDILEAHPDTALVLPLHKNPTVREPLQGILGAHPRAFLDEPFDYPQLVGALQRSTLVLTD
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCEEEEEC
SGGLQEEAPAFGKPVLVLRETTERPEAIEAGVALKVGTDRTAIARAAHALLTDDALYGQM
CCCCCCCCCCCCCCEEEEECCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
ARAVNPFGDGHATGRILRSTLAFLGLPSD
HHHCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]