Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 37520062

GI number: 37520062

Start: 529249

End: 530481

Strand: Reverse

Name: macB [H]

Synonym: gll0493

Alternate gene names: 37520062

Gene position: 530481-529249 (Counterclockwise)

Preceding gene: 37520063

Following gene: 37520061

Centisome position: 11.39

GC content: 61.31

Gene sequence:

>1233_bases
ATGTCGTGGCTTGAGAATCTGAAAATCGCGGCGGTGGCTCTGTGGGCCAACTGGTTGCGCTCGGTGCTCACGATGCTGGG
GCTGATCATCGGCGTTGGTTCGGTGGTGCTCATCGTGGCCATTGGCGTGGGCACCCAAAAATTCGTCAAAGACCAGTTTC
GCAGCTTCGGCACCAACGTGGTGGTGGTGGGCGAGGACCGGCCGCCCGACGGCCTCACCCAGAATACCGACCGCCGCATC
AGGCCCCTCACAATCGAGGATATGGAGGCTTTGCGTACCCAGATTGGCGCCATCAGCCGGGCATCGGGCATCTTGTCTGA
GAACGGGCGCGTCGTCTGGAACAACAAAGACGCCGACGGCCGCATCTACGGCATGGAGCCCGAACTGGCGCGCATCCTCA
ACTGGTCGGTACGCAAGGGACGATTTTTTACCGATAAAGAGGTACAGCAGCGCGCCCGGGTGGCGGTCCTGGGCGAGGAG
ATTGCCGATGAGCTGTTTGGCACCGAGCAGCCGGTGGGCAAGCAAATCCTGGTCAACGGCCGCACGATGACGGTAATTGG
CGTGCTGGAAAAGCGCTCGGGTGCTTTTAGGGGCTATCTGCAATTTCTGGAGCGCGGCGCCATCATGCCCTTCACGGTGG
TGCAGGAGTCGCTCATCAGCAATGTTACGCCCTTCGGGCGGCGGGTAAGGATTATTTTTCTGGAGACCAAACCGGCCGAA
ACTATTGAGGCTGTGACCTTTCAGGTGACCAATCTGTTGCGCGCCCGCCACCAGATCACCGCCGAGGACGACTTTTTTGT
CGGCAACGCCCAGGAAATTCTCAACGTGTTCAATGCCATTGCCGCCGGGCTCACGGTCATGCTGGGGCTGATTGCTGCGA
TTGCCCTGCTGGTGGGCGGCATCAACATCATGAACATCATGCTCGTTTCGGTGACCGAGCGCACCCGCGAGATTGGCCTC
AGAAAAGCCCTCGGCGCCAGCGAAGGCGTGATCCTCGCCCAGTTTGTGATCGAAGCGGTGCTCATCTCGGTGTTAGGCGG
CCTGATCGGTCTGGGTCTCGGTTGGGGCGCCGCCGCCCTGGTGGGCGCGCTGAGCCCCATCAAGCCCGAGGTGACACCCA
TGGCGGTCTTTTTGGCCGTGGGTGTGGCCACTGGCATCGGTCTATTTTTTGGAGTCTTCCCGGCCCGCCGGGCTGCCCGG
CTCGACCCGATCGTCGCCCTTCGCACGGAGTAA

Upstream 100 bases:

>100_bases
GACGGGCTTGTTTTTTGGAGTCTTCCCGGCCCGCCGCGCTGCCCGGCTCGACCCGATCGTCGCTTTGAGAAGCGAATAGC
GACCCACAAGGAGTTTGCCG

Downstream 100 bases:

>100_bases
CCCGCATGCTTATCCGCCTCGAAAACATCCGCAAGTCCTACAAATTGGGCAACAACGAGGTGCCCGTGCTGCGGGGCATC
GACCTCGACATCGACCGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSWLENLKIAAVALWANWLRSVLTMLGLIIGVGSVVLIVAIGVGTQKFVKDQFRSFGTNVVVVGEDRPPDGLTQNTDRRI
RPLTIEDMEALRTQIGAISRASGILSENGRVVWNNKDADGRIYGMEPELARILNWSVRKGRFFTDKEVQQRARVAVLGEE
IADELFGTEQPVGKQILVNGRTMTVIGVLEKRSGAFRGYLQFLERGAIMPFTVVQESLISNVTPFGRRVRIIFLETKPAE
TIEAVTFQVTNLLRARHQITAEDDFFVGNAQEILNVFNAIAAGLTVMLGLIAAIALLVGGINIMNIMLVSVTERTREIGL
RKALGASEGVILAQFVIEAVLISVLGGLIGLGLGWGAAALVGALSPIKPEVTPMAVFLAVGVATGIGLFFGVFPARRAAR
LDPIVALRTE

Sequences:

>Translated_410_residues
MSWLENLKIAAVALWANWLRSVLTMLGLIIGVGSVVLIVAIGVGTQKFVKDQFRSFGTNVVVVGEDRPPDGLTQNTDRRI
RPLTIEDMEALRTQIGAISRASGILSENGRVVWNNKDADGRIYGMEPELARILNWSVRKGRFFTDKEVQQRARVAVLGEE
IADELFGTEQPVGKQILVNGRTMTVIGVLEKRSGAFRGYLQFLERGAIMPFTVVQESLISNVTPFGRRVRIIFLETKPAE
TIEAVTFQVTNLLRARHQITAEDDFFVGNAQEILNVFNAIAAGLTVMLGLIAAIALLVGGINIMNIMLVSVTERTREIGL
RKALGASEGVILAQFVIEAVLISVLGGLIGLGLGWGAAALVGALSPIKPEVTPMAVFLAVGVATGIGLFFGVFPARRAAR
LDPIVALRTE
>Mature_409_residues
SWLENLKIAAVALWANWLRSVLTMLGLIIGVGSVVLIVAIGVGTQKFVKDQFRSFGTNVVVVGEDRPPDGLTQNTDRRIR
PLTIEDMEALRTQIGAISRASGILSENGRVVWNNKDADGRIYGMEPELARILNWSVRKGRFFTDKEVQQRARVAVLGEEI
ADELFGTEQPVGKQILVNGRTMTVIGVLEKRSGAFRGYLQFLERGAIMPFTVVQESLISNVTPFGRRVRIIFLETKPAET
IEAVTFQVTNLLRARHQITAEDDFFVGNAQEILNVFNAIAAGLTVMLGLIAAIALLVGGINIMNIMLVSVTERTREIGLR
KALGASEGVILAQFVIEAVLISVLGGLIGLGLGWGAAALVGALSPIKPEVTPMAVFLAVGVATGIGLFFGVFPARRAARL
DPIVALRTE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=414, Percent_Identity=35.7487922705314, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44397; Mature: 44266

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLENLKIAAVALWANWLRSVLTMLGLIIGVGSVVLIVAIGVGTQKFVKDQFRSFGTNV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
VVVGEDRPPDGLTQNTDRRIRPLTIEDMEALRTQIGAISRASGILSENGRVVWNNKDADG
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCEEEECCCCCCC
RIYGMEPELARILNWSVRKGRFFTDKEVQQRARVAVLGEEIADELFGTEQPVGKQILVNG
EEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
RTMTVIGVLEKRSGAFRGYLQFLERGAIMPFTVVQESLISNVTPFGRRVRIIFLETKPAE
CEEEEEEEHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCH
TIEAVTFQVTNLLRARHQITAEDDFFVGNAQEILNVFNAIAAGLTVMLGLIAAIALLVGG
HHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INIMNIMLVSVTERTREIGLRKALGASEGVILAQFVIEAVLISVLGGLIGLGLGWGAAAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VGALSPIKPEVTPMAVFLAVGVATGIGLFFGVFPARRAARLDPIVALRTE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
SWLENLKIAAVALWANWLRSVLTMLGLIIGVGSVVLIVAIGVGTQKFVKDQFRSFGTNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
VVVGEDRPPDGLTQNTDRRIRPLTIEDMEALRTQIGAISRASGILSENGRVVWNNKDADG
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCEEEECCCCCCC
RIYGMEPELARILNWSVRKGRFFTDKEVQQRARVAVLGEEIADELFGTEQPVGKQILVNG
EEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
RTMTVIGVLEKRSGAFRGYLQFLERGAIMPFTVVQESLISNVTPFGRRVRIIFLETKPAE
CEEEEEEEHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCH
TIEAVTFQVTNLLRARHQITAEDDFFVGNAQEILNVFNAIAAGLTVMLGLIAAIALLVGG
HHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
INIMNIMLVSVTERTREIGLRKALGASEGVILAQFVIEAVLISVLGGLIGLGLGWGAAAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VGALSPIKPEVTPMAVFLAVGVATGIGLFFGVFPARRAARLDPIVALRTE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA