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The map label for this gene is macB [H]

Identifier: 37520063

GI number: 37520063

Start: 530503

End: 531630

Strand: Reverse

Name: macB [H]

Synonym: gll0494

Alternate gene names: 37520063

Gene position: 531630-530503 (Counterclockwise)

Preceding gene: 37520064

Following gene: 37520062

Centisome position: 11.41

GC content: 63.3

Gene sequence:

>1128_bases
ATGGTGGGCCTGATTATCGGCGTCGGGGCGGTGATCCTGGTGATCGCCCTCGGGGTGGGGGCTCAGAACTTCGTCAAAGA
TCAGTTTCGAGGACTGGGTACCAATGTCGTGGGGGTCTACGACGGTGGTCCGCGCACTAAGGGCCGTCGCCCCCTCACCC
TCGCCGATGTCGAGGCGGTGCGCACCCAGGCGCCCGCGGTGGAAGCGGTGGCGCCACTGGCTCTGGGCAACGCCTCGGTC
TCCTGGGGATCGCGCAAGTCCCAGGCGCAGTTGACCGGAGTACCCCCCAATCTAGAGCGCGTTACGCGCCTCGGTTACTC
TAAAGGCCGCTTCTTCAGCCTGGGTGAGGTCGAAAGCCGTGCCCGGGTGGCCATCCTAGGCGAGACCCTCGCCAAGAAGC
TCTTTAGCTTTGAAGATCCGATCGGCAAGACGATCGTCGTCAACAATCGCCAGCTCACCGTCGTGGGCGTCACCCGCCCG
AGTTTCGGCGGCTGGATCGATGTGGATCGCGGGGTGCTGGTGCCGTTACCCCTGGCGCTGGAGAGTCTGATTGCAAGCGA
TTCGCCCTTCGGTAAAAAAGTGGGCGGCTTTCTGGCGGCGACCAAGGCCGACTCGACCATCGACCAAGTCACCTTCGAGC
TCAAAAACCTGCTCCGCTTGCGCCACAACGTCACCGACAAAGACGATTTTTTGATCGGCAACATCCAGGAGACGCTCGAT
CTGTTCAACAACATCGCCCTCGGGGTGACGGTGGTGCTGGGGCTCACGGCGGCCATCTCGCTGGTGGTGAGCGGCATCGG
GATTATGAACATCATGCTCGTTTCGGTGACCGAGCGCACCCGCGAGATTGGCCTCAGAAAAGCCCTCGGCGCCAGCGAAG
AAGTGATCCTCGCCCAGTTTGTCACCGAGGCGGTGCTGCTTTCGGTGCTGGGCGGTCTTCTCGGCATGGCCTGGGGTCTG
GCGGCGGCGGTGGCCGTCGGCCAGTTCTCGCCTTTTAAGCCCGAGATCACCCCCTGGTCGGTGGTGCTTGCTCTCGGGGT
CTCGGTGGCGACGGGCTTGTTTTTTGGAGTCTTCCCGGCCCGCCGCGCTGCCCGGCTCGACCCGATCGTCGCTTTGAGAA
GCGAATAG

Upstream 100 bases:

>100_bases
CTCTCCCGCACTACTCGGAGATCCGGCCTTGGACTGGTACGAGAATCTCAAACTGGCCGCCGCGACCCTCTGGGCCAGCC
GACTGCGGACCATTCTGACG

Downstream 100 bases:

>100_bases
CGACCCACAAGGAGTTTGCCGATGTCGTGGCTTGAGAATCTGAAAATCGCGGCGGTGGCTCTGTGGGCCAACTGGTTGCG
CTCGGTGCTCACGATGCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVGLIIGVGAVILVIALGVGAQNFVKDQFRGLGTNVVGVYDGGPRTKGRRPLTLADVEAVRTQAPAVEAVAPLALGNASV
SWGSRKSQAQLTGVPPNLERVTRLGYSKGRFFSLGEVESRARVAILGETLAKKLFSFEDPIGKTIVVNNRQLTVVGVTRP
SFGGWIDVDRGVLVPLPLALESLIASDSPFGKKVGGFLAATKADSTIDQVTFELKNLLRLRHNVTDKDDFLIGNIQETLD
LFNNIALGVTVVLGLTAAISLVVSGIGIMNIMLVSVTERTREIGLRKALGASEEVILAQFVTEAVLLSVLGGLLGMAWGL
AAAVAVGQFSPFKPEITPWSVVLALGVSVATGLFFGVFPARRAARLDPIVALRSE

Sequences:

>Translated_375_residues
MVGLIIGVGAVILVIALGVGAQNFVKDQFRGLGTNVVGVYDGGPRTKGRRPLTLADVEAVRTQAPAVEAVAPLALGNASV
SWGSRKSQAQLTGVPPNLERVTRLGYSKGRFFSLGEVESRARVAILGETLAKKLFSFEDPIGKTIVVNNRQLTVVGVTRP
SFGGWIDVDRGVLVPLPLALESLIASDSPFGKKVGGFLAATKADSTIDQVTFELKNLLRLRHNVTDKDDFLIGNIQETLD
LFNNIALGVTVVLGLTAAISLVVSGIGIMNIMLVSVTERTREIGLRKALGASEEVILAQFVTEAVLLSVLGGLLGMAWGL
AAAVAVGQFSPFKPEITPWSVVLALGVSVATGLFFGVFPARRAARLDPIVALRSE
>Mature_375_residues
MVGLIIGVGAVILVIALGVGAQNFVKDQFRGLGTNVVGVYDGGPRTKGRRPLTLADVEAVRTQAPAVEAVAPLALGNASV
SWGSRKSQAQLTGVPPNLERVTRLGYSKGRFFSLGEVESRARVAILGETLAKKLFSFEDPIGKTIVVNNRQLTVVGVTRP
SFGGWIDVDRGVLVPLPLALESLIASDSPFGKKVGGFLAATKADSTIDQVTFELKNLLRLRHNVTDKDDFLIGNIQETLD
LFNNIALGVTVVLGLTAAISLVVSGIGIMNIMLVSVTERTREIGLRKALGASEEVILAQFVTEAVLLSVLGGLLGMAWGL
AAAVAVGQFSPFKPEITPWSVVLALGVSVATGLFFGVFPARRAARLDPIVALRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=386, Percent_Identity=34.4559585492228, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 39545; Mature: 39545

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLIIGVGAVILVIALGVGAQNFVKDQFRGLGTNVVGVYDGGPRTKGRRPLTLADVEAV
CEEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHHHH
RTQAPAVEAVAPLALGNASVSWGSRKSQAQLTGVPPNLERVTRLGYSKGRFFSLGEVESR
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCHHHHHHCCCCCCCEEECCCCCCC
ARVAILGETLAKKLFSFEDPIGKTIVVNNRQLTVVGVTRPSFGGWIDVDRGVLVPLPLAL
CCEEHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEECCCCCCEEECCCCEEEEHHHHH
ESLIASDSPFGKKVGGFLAATKADSTIDQVTFELKNLLRLRHNVTDKDDFLIGNIQETLD
HHHHCCCCCCCHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHH
LFNNIALGVTVVLGLTAAISLVVSGIGIMNIMLVSVTERTREIGLRKALGASEEVILAQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VTEAVLLSVLGGLLGMAWGLAAAVAVGQFSPFKPEITPWSVVLALGVSVATGLFFGVFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRAARLDPIVALRSE
HHHHCCCCCEEECCC
>Mature Secondary Structure
MVGLIIGVGAVILVIALGVGAQNFVKDQFRGLGTNVVGVYDGGPRTKGRRPLTLADVEAV
CEEEHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEHHHHHHH
RTQAPAVEAVAPLALGNASVSWGSRKSQAQLTGVPPNLERVTRLGYSKGRFFSLGEVESR
HHCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCHHHHHHCCCCCCCEEECCCCCCC
ARVAILGETLAKKLFSFEDPIGKTIVVNNRQLTVVGVTRPSFGGWIDVDRGVLVPLPLAL
CCEEHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEECCCCCCEEECCCCEEEEHHHHH
ESLIASDSPFGKKVGGFLAATKADSTIDQVTFELKNLLRLRHNVTDKDDFLIGNIQETLD
HHHHCCCCCCCHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHH
LFNNIALGVTVVLGLTAAISLVVSGIGIMNIMLVSVTERTREIGLRKALGASEEVILAQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VTEAVLLSVLGGLLGMAWGLAAAVAVGQFSPFKPEITPWSVVLALGVSVATGLFFGVFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRAARLDPIVALRSE
HHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA