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The map label for this gene is infA

Identifier: 37519982

GI number: 37519982

Start: 431960

End: 432181

Strand: Direct

Name: infA

Synonym: gvip041

Alternate gene names: 37519982

Gene position: 431960-432181 (Clockwise)

Preceding gene: 37519981

Following gene: 37519987

Centisome position: 9.27

GC content: 56.76

Gene sequence:

>222_bases
TTGGCAAAGCAAGACGTCATTGAGATGGAAGGAACCGTTGTCGAGTCGCTCCCCAACGCCATGTTTCGGGTCGAACTCGA
CAACAGTTTCAACATCCTCGCCCACATCTCCGGCAAGATCCGCCGCAACTACATCAAGATCCTGCCCGGCGACCGCGTCA
AAGTCGAATTGACCCCCTACGATCTCACCAAGGGGCGCATCACCTACCGCCTGCGCAAGTAG

Upstream 100 bases:

>100_bases
CGCTCTCAGCCCAGTTCGAACACACAGTTCTGGTCACCCGAGACGGCTACGAGATTCTTACCGACCGTTCGAAGGTCTGA
CCTTTATTCAGGAGTTGTCC

Downstream 100 bases:

>100_bases
GCGGCCCCCGGCCCGCTCAGCCGGTGTTGCGCATACCGGCGGCGATGCCGTTGATGGTCAATAGCGCCCCCCGCAACAGC
TCGTTGCGCGAATAGGATCG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MAKQDVIEMEGTVVESLPNAMFRVELDNSFNILAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRK

Sequences:

>Translated_73_residues
MAKQDVIEMEGTVVESLPNAMFRVELDNSFNILAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRK
>Mature_72_residues
AKQDVIEMEGTVVESLPNAMFRVELDNSFNILAHISGKIRRNYIKILPGDRVKVELTPYDLTKGRITYRLRK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=69.4444444444444, Blast_Score=110, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_GLOVI (Q7NNJ8)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_923359.1
- ProteinModelPortal:   Q7NNJ8
- SMR:   Q7NNJ8
- GeneID:   2599717
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.413
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- ProtClustDB:   PRK00276
- BioCyc:   GVIO251221:GSR0413-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8463; Mature: 8332

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQDVIEMEGTVVESLPNAMFRVELDNSFNILAHISGKIRRNYIKILPGDRVKVELTPY
CCCCCEEECCCEEECCCCCEEEEEEECCCEEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTKGRITYRLRK
CCCCCEEEEEEEC
>Mature Secondary Structure 
AKQDVIEMEGTVVESLPNAMFRVELDNSFNILAHISGKIRRNYIKILPGDRVKVELTPY
CCCCEEECCCEEECCCCCEEEEEEECCCEEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTKGRITYRLRK
CCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292