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The map label for this gene is fhuA [H]

Identifier: 37519923

GI number: 37519923

Start: 370758

End: 371231

Strand: Direct

Name: fhuA [H]

Synonym: glr0354

Alternate gene names: 37519923

Gene position: 370758-371231 (Clockwise)

Preceding gene: 37519922

Following gene: 37519925

Centisome position: 7.96

GC content: 65.82

Gene sequence:

>474_bases
GTGCCTACATGCCCAATAATCCGCCGCAGCGCCACCGGTCAACTCTTTAGACCCGTCACCGGCGTCCAGTACGAAGTCGG
GGCCAAGGCGGAACTGGCAGGCGGCCGCTCTCTGGCCACCGCCGCCCTCTACGAGCTCACCAAGCAGAATGCGCTGACCA
CCGACCCGGACAACCCGCTATTTTCCATCCAGACCGGTGAGGTGCAAAGCAAGGGCTTCGAGGTGGACCTCTCCGGCCGG
CCGCTGCCGGGCTGGGACATCTACGCCTCCTATGCCTACATCGATGCGCGCTACACCCGCGACAACGACATCGCCGTGGG
CACCGAAGTGGGCGGGGTGCCAGGAACATCGCTTTACAGGTCAGTGGGCGGCCAGACGACGTCCGCTGGCCATTGCGGCT
GGTGCATGGGGCGGGCCCGTTGCTGTGATGGCGCCATTGTAGCTGTGGCTCCGGGCGCAGGGTGGACCCGTTGA

Upstream 100 bases:

>100_bases
CAAAACCAGGGCGTTTGCTGTTCGAGGCTTAATTTGGCAGCCATCTTGATGGTTTTGTCAATGCAGTGGGCGTACCTGGG
TAGGAGGTTTAGGCACGAGA

Downstream 100 bases:

>100_bases
AAGAAGATGCGCCACCGGGGTGCGCGTCAAAAGTGCTCGGCGGCTCGCTGTGCCCATCGGTTCTTCCCGAGCGGGCCAGA
CGGATGCTGGAGTTCACGCT

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MPTCPIIRRSATGQLFRPVTGVQYEVGAKAELAGGRSLATAALYELTKQNALTTDPDNPLFSIQTGEVQSKGFEVDLSGR
PLPGWDIYASYAYIDARYTRDNDIAVGTEVGGVPGTSLYRSVGGQTTSAGHCGWCMGRARCCDGAIVAVAPGAGWTR

Sequences:

>Translated_157_residues
MPTCPIIRRSATGQLFRPVTGVQYEVGAKAELAGGRSLATAALYELTKQNALTTDPDNPLFSIQTGEVQSKGFEVDLSGR
PLPGWDIYASYAYIDARYTRDNDIAVGTEVGGVPGTSLYRSVGGQTTSAGHCGWCMGRARCCDGAIVAVAPGAGWTR
>Mature_156_residues
PTCPIIRRSATGQLFRPVTGVQYEVGAKAELAGGRSLATAALYELTKQNALTTDPDNPLFSIQTGEVQSKGFEVDLSGRP
LPGWDIYASYAYIDARYTRDNDIAVGTEVGGVPGTSLYRSVGGQTTSAGHCGWCMGRARCCDGAIVAVAPGAGWTR

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=89, Percent_Identity=38.2022471910112, Blast_Score=67, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 16550; Mature: 16419

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTCPIIRRSATGQLFRPVTGVQYEVGAKAELAGGRSLATAALYELTKQNALTTDPDNPL
CCCCCCEECCCCCCEECCCCCCEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCE
FSIQTGEVQSKGFEVDLSGRPLPGWDIYASYAYIDARYTRDNDIAVGTEVGGVPGTSLYR
EEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEEEEEEECCCCEEEECCCCCCCCHHHHH
SVGGQTTSAGHCGWCMGRARCCDGAIVAVAPGAGWTR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
PTCPIIRRSATGQLFRPVTGVQYEVGAKAELAGGRSLATAALYELTKQNALTTDPDNPL
CCCCCEECCCCCCEECCCCCCEEECCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCE
FSIQTGEVQSKGFEVDLSGRPLPGWDIYASYAYIDARYTRDNDIAVGTEVGGVPGTSLYR
EEEECCCCCCCCEEEEECCCCCCCCEEEEEEEEEEEEEECCCCEEEECCCCCCCCHHHHH
SVGGQTTSAGHCGWCMGRARCCDGAIVAVAPGAGWTR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]