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The map label for this gene is fhuA [H]

Identifier: 37519922

GI number: 37519922

Start: 368398

End: 370635

Strand: Direct

Name: fhuA [H]

Synonym: glr0353

Alternate gene names: 37519922

Gene position: 368398-370635 (Clockwise)

Preceding gene: 37519921

Following gene: 37519923

Centisome position: 7.91

GC content: 50.31

Gene sequence:

>2238_bases
ATGAGAAGCGGTTTGCAAGGGATCCGCTGCGGTTCCTTGGTCACCCTTGCTTGGGCAGTTTTTGTTGGATGTAGCTCTCA
ACTGTTTGCTGCATCTGTGGCCACGGCTGGCGGGGTAGTATCTATCCCGCGCAAGGCGGATCTGCAGCCGGTGCGCACCG
AGGCGCGGGAGTTGCTGGCAAGTCCGCTGGCCCAGGCGGTTCCGGCCGCTTCCGCACCGGAGCCGACGGCACAGCGCCCC
CCGGACGACGCCGAAGACCTCGACGAGGTGACGGTGACCGGCGAGAGACGGCGGCGGTATCTGGTGCCCGATACGAGCAC
GGCCACCAAAATCGACACGCCGATCCGGGATCTGCCGCTGTCAATCCAGGTGGTTCCCCAACAGGTGCTCGAAGATCGCA
AGGTGAGAAATGTAACCGAGGCGGTAGAAACGGTCAGCGGTGTTGTCGATGGTGGAGACCTCTTCGGTGCTCCCTCAGGA
GCCAGAATCATCAGGGGATTTGAACAGTCGGGAAATTTTCGAAACGGCTATCGAGACGTCGGTTACTACGCCCTGACAGG
CGTTGGGACGATCGAGCAAGTGGAAGTGCTCAAAGGCCCTGCTTCGGTCCTGTTCGGGGCAGTGGAACCTGGTGGGCTCA
TCAACGTTGTCACCAAACGCCCCCTGAGTGAACCCTATTACAATGTCGCAATTCAGGCAGGCAACCTCGGTTATTATCAG
CCCAGCATCGATTTGTCCGGACCTCTGAATTCGGATAAAACCTTGCTCTACCGCGTCAACGCAAACTATCAAGGTTTGGA
CGGTTTTCAGAACTTTGTCACTACCAATCTGACCACGATCTCACCCACGGTTACTTGGAAGCTGGGGGATAAAACAGTTC
TGAACTTACACTATGAATACATTAGATTCTTCGCGAATCCTCCTGAAAGTTACGCTGTGCTCCTCAGCGACGGTAGGATG
ACGCCTCGGAATCTCTATCTCTCCTATCCCAGTTTAGCATTTAACGATATTGTCACTCAAAAATATGGCTATTCGCTGAG
TCATCAGTTCAACGATGATTGGCAGATTCGCAACAGCTTTTCTGTGGCTGCCAGCAATACTAAAGAAGCGCAAGTATACG
GGACAAGCCTTGTAAGCGACCGTTTCGTGGACATCGATGCATACGATCTTAAATATGCGCAAGACAACTATTTTGGACAA
ATCGACTTAATTGGAAAATTCAAGACGGGATCGATATCGCACCAACTCTTGCTGGGCTTTGATTTCAATCGCTTTGTCGA
CGTTTACAATGGTTATTTCAACACCGATTTACCCGCTCTAGATATTCTTAACCCGAACTATAACATTCCAAAGCCTGACT
ATGTTCCATTTTTTGACTTCTATCAGCCCATCCAGTCCTATGGCGTCTATCTCCAAGATCAGGTTACTTTTCTCGACAAC
CTAAAGCTGCTGGTTGGTGGCCGATTAGACTGGGTTTCACAAAAATTTGCTACAGGCACACCTGACGCTCCAATACAGAA
TGACAGCGCTTTCAGCCCTCGAATCGGACTGGTCTATCAGCCGAGCGAATCCGTTTCTCTCTACACCAGCTACAGTCAAT
CGTTCAATCCCACCCAGGGTTTCAACCCTGATGGCGCGGCGTTCAAACCTACCAAGGGAGCGCAATATGAAGCGGGTATT
AAAGTTGATTTCCTGGACAGACGGCTTTCGACAACCTTGGCAGCTTATCAGATAATCAAGGAGAATGTAAGAACTGTTGA
TCCCAACAATCCTTTATTTTCTATTCAAGTAGGCGAACAAAGAAGCCAGGGAATTGAGTTGGATTTTGCAGGACAGGTAT
TGCCAGGATGGAAGATAATCGGTTCTTACGCTTACACCGACGGCGAAGTGACCGGAGACAACCTTATTCCTGCAGGTAAC
AAATTAAGAAATGTGCCGGAGCATCAAGCCAGCCTCTGGACAACCTACGAGATCCCGCAGGGTAATCTGAAGGGTTTGGG
ATTCGGCTTGGGGCTTTTTTACGTAGGCTCGCGAGCTGGAGATTTACCCAACACATTCACGCTACCGGACTACTTGCGTA
CCGATGCCAAGCTTTATTACCGTAATAGTGGCTTAAACGCCGCCATCAATATTCGCAATTTATTTGACATGGACTATGTC
AGAAGCAGCTTCAACAACATTTTTCTTCAAAGAGGTGCACCGTTGACTATCACCTGTTCTATCGGTTGGGAACTCTAA

Upstream 100 bases:

>100_bases
CTCTGCACTAGTCTGCGGGAGACAGTTGGAGAGCGGGCTTTGGCCCGTTTTCCCTTTCTGCGGCTACTTCGCTCTCGCCA
TTATTTCTGAGGTCTTGCAG

Downstream 100 bases:

>100_bases
CGAATATTTCTCGTTTCGTTGGCAAAACCAGGGCGTTTGCTGTTCGAGGCTTAATTTGGCAGCCATCTTGATGGTTTTGT
CAATGCAGTGGGCGTACCTG

Product: ferrichrome-iron receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MRSGLQGIRCGSLVTLAWAVFVGCSSQLFAASVATAGGVVSIPRKADLQPVRTEARELLASPLAQAVPAASAPEPTAQRP
PDDAEDLDEVTVTGERRRRYLVPDTSTATKIDTPIRDLPLSIQVVPQQVLEDRKVRNVTEAVETVSGVVDGGDLFGAPSG
ARIIRGFEQSGNFRNGYRDVGYYALTGVGTIEQVEVLKGPASVLFGAVEPGGLINVVTKRPLSEPYYNVAIQAGNLGYYQ
PSIDLSGPLNSDKTLLYRVNANYQGLDGFQNFVTTNLTTISPTVTWKLGDKTVLNLHYEYIRFFANPPESYAVLLSDGRM
TPRNLYLSYPSLAFNDIVTQKYGYSLSHQFNDDWQIRNSFSVAASNTKEAQVYGTSLVSDRFVDIDAYDLKYAQDNYFGQ
IDLIGKFKTGSISHQLLLGFDFNRFVDVYNGYFNTDLPALDILNPNYNIPKPDYVPFFDFYQPIQSYGVYLQDQVTFLDN
LKLLVGGRLDWVSQKFATGTPDAPIQNDSAFSPRIGLVYQPSESVSLYTSYSQSFNPTQGFNPDGAAFKPTKGAQYEAGI
KVDFLDRRLSTTLAAYQIIKENVRTVDPNNPLFSIQVGEQRSQGIELDFAGQVLPGWKIIGSYAYTDGEVTGDNLIPAGN
KLRNVPEHQASLWTTYEIPQGNLKGLGFGLGLFYVGSRAGDLPNTFTLPDYLRTDAKLYYRNSGLNAAINIRNLFDMDYV
RSSFNNIFLQRGAPLTITCSIGWEL

Sequences:

>Translated_745_residues
MRSGLQGIRCGSLVTLAWAVFVGCSSQLFAASVATAGGVVSIPRKADLQPVRTEARELLASPLAQAVPAASAPEPTAQRP
PDDAEDLDEVTVTGERRRRYLVPDTSTATKIDTPIRDLPLSIQVVPQQVLEDRKVRNVTEAVETVSGVVDGGDLFGAPSG
ARIIRGFEQSGNFRNGYRDVGYYALTGVGTIEQVEVLKGPASVLFGAVEPGGLINVVTKRPLSEPYYNVAIQAGNLGYYQ
PSIDLSGPLNSDKTLLYRVNANYQGLDGFQNFVTTNLTTISPTVTWKLGDKTVLNLHYEYIRFFANPPESYAVLLSDGRM
TPRNLYLSYPSLAFNDIVTQKYGYSLSHQFNDDWQIRNSFSVAASNTKEAQVYGTSLVSDRFVDIDAYDLKYAQDNYFGQ
IDLIGKFKTGSISHQLLLGFDFNRFVDVYNGYFNTDLPALDILNPNYNIPKPDYVPFFDFYQPIQSYGVYLQDQVTFLDN
LKLLVGGRLDWVSQKFATGTPDAPIQNDSAFSPRIGLVYQPSESVSLYTSYSQSFNPTQGFNPDGAAFKPTKGAQYEAGI
KVDFLDRRLSTTLAAYQIIKENVRTVDPNNPLFSIQVGEQRSQGIELDFAGQVLPGWKIIGSYAYTDGEVTGDNLIPAGN
KLRNVPEHQASLWTTYEIPQGNLKGLGFGLGLFYVGSRAGDLPNTFTLPDYLRTDAKLYYRNSGLNAAINIRNLFDMDYV
RSSFNNIFLQRGAPLTITCSIGWEL
>Mature_745_residues
MRSGLQGIRCGSLVTLAWAVFVGCSSQLFAASVATAGGVVSIPRKADLQPVRTEARELLASPLAQAVPAASAPEPTAQRP
PDDAEDLDEVTVTGERRRRYLVPDTSTATKIDTPIRDLPLSIQVVPQQVLEDRKVRNVTEAVETVSGVVDGGDLFGAPSG
ARIIRGFEQSGNFRNGYRDVGYYALTGVGTIEQVEVLKGPASVLFGAVEPGGLINVVTKRPLSEPYYNVAIQAGNLGYYQ
PSIDLSGPLNSDKTLLYRVNANYQGLDGFQNFVTTNLTTISPTVTWKLGDKTVLNLHYEYIRFFANPPESYAVLLSDGRM
TPRNLYLSYPSLAFNDIVTQKYGYSLSHQFNDDWQIRNSFSVAASNTKEAQVYGTSLVSDRFVDIDAYDLKYAQDNYFGQ
IDLIGKFKTGSISHQLLLGFDFNRFVDVYNGYFNTDLPALDILNPNYNIPKPDYVPFFDFYQPIQSYGVYLQDQVTFLDN
LKLLVGGRLDWVSQKFATGTPDAPIQNDSAFSPRIGLVYQPSESVSLYTSYSQSFNPTQGFNPDGAAFKPTKGAQYEAGI
KVDFLDRRLSTTLAAYQIIKENVRTVDPNNPLFSIQVGEQRSQGIELDFAGQVLPGWKIIGSYAYTDGEVTGDNLIPAGN
KLRNVPEHQASLWTTYEIPQGNLKGLGFGLGLFYVGSRAGDLPNTFTLPDYLRTDAKLYYRNSGLNAAINIRNLFDMDYV
RSSFNNIFLQRGAPLTITCSIGWEL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=688, Percent_Identity=32.8488372093023, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI1787024, Length=737, Percent_Identity=24.5590230664858, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787344, Length=662, Percent_Identity=25.8308157099698, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82201; Mature: 82201

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGLQGIRCGSLVTLAWAVFVGCSSQLFAASVATAGGVVSIPRKADLQPVRTEARELLA
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
SPLAQAVPAASAPEPTAQRPPDDAEDLDEVTVTGERRRRYLVPDTSTATKIDTPIRDLPL
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCCCCCCHHHCCE
SIQVVPQQVLEDRKVRNVTEAVETVSGVVDGGDLFGAPSGARIIRGFEQSGNFRNGYRDV
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCC
GYYALTGVGTIEQVEVLKGPASVLFGAVEPGGLINVVTKRPLSEPYYNVAIQAGNLGYYQ
CEEEEECCCCHHHHHHHCCCCHHEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEC
PSIDLSGPLNSDKTLLYRVNANYQGLDGFQNFVTTNLTTISPTVTWKLGDKTVLNLHYEY
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCEEEECCEEEEEECCEEEEEEEEHH
IRFFANPPESYAVLLSDGRMTPRNLYLSYPSLAFNDIVTQKYGYSLSHQFNDDWQIRNSF
HHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCE
SVAASNTKEAQVYGTSLVSDRFVDIDAYDLKYAQDNYFGQIDLIGKFKTGSISHQLLLGF
EEEECCCCCEEEEEEHHHCCCEEECCHHEEEECCCCCCEEEEEEEEECCCCCCEEEEEEC
DFNRFVDVYNGYFNTDLPALDILNPNYNIPKPDYVPFFDFYQPIQSYGVYLQDQVTFLDN
CHHHHHHHHCCEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEHHHC
LKLLVGGRLDWVSQKFATGTPDAPIQNDSAFSPRIGLVYQPSESVSLYTSYSQSFNPTQG
EEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCC
FNPDGAAFKPTKGAQYEAGIKVDFLDRRLSTTLAAYQIIKENVRTVDPNNPLFSIQVGEQ
CCCCCCCCCCCCCCCEECCEEEEHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCC
RSQGIELDFAGQVLPGWKIIGSYAYTDGEVTGDNLIPAGNKLRNVPEHQASLWTTYEIPQ
CCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCHHHCEEEEEECCC
GNLKGLGFGLGLFYVGSRAGDLPNTFTLPDYLRTDAKLYYRNSGLNAAINIRNLFDMDYV
CCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHH
RSSFNNIFLQRGAPLTITCSIGWEL
HHHHHHEEEECCCCEEEEEECCCCC
>Mature Secondary Structure
MRSGLQGIRCGSLVTLAWAVFVGCSSQLFAASVATAGGVVSIPRKADLQPVRTEARELLA
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
SPLAQAVPAASAPEPTAQRPPDDAEDLDEVTVTGERRRRYLVPDTSTATKIDTPIRDLPL
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCCCCCCHHHCCE
SIQVVPQQVLEDRKVRNVTEAVETVSGVVDGGDLFGAPSGARIIRGFEQSGNFRNGYRDV
EEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCC
GYYALTGVGTIEQVEVLKGPASVLFGAVEPGGLINVVTKRPLSEPYYNVAIQAGNLGYYQ
CEEEEECCCCHHHHHHHCCCCHHEEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEC
PSIDLSGPLNSDKTLLYRVNANYQGLDGFQNFVTTNLTTISPTVTWKLGDKTVLNLHYEY
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCEEEECCEEEEEECCEEEEEEEEHH
IRFFANPPESYAVLLSDGRMTPRNLYLSYPSLAFNDIVTQKYGYSLSHQFNDDWQIRNSF
HHHHCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECCE
SVAASNTKEAQVYGTSLVSDRFVDIDAYDLKYAQDNYFGQIDLIGKFKTGSISHQLLLGF
EEEECCCCCEEEEEEHHHCCCEEECCHHEEEECCCCCCEEEEEEEEECCCCCCEEEEEEC
DFNRFVDVYNGYFNTDLPALDILNPNYNIPKPDYVPFFDFYQPIQSYGVYLQDQVTFLDN
CHHHHHHHHCCEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEEHHHC
LKLLVGGRLDWVSQKFATGTPDAPIQNDSAFSPRIGLVYQPSESVSLYTSYSQSFNPTQG
EEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCC
FNPDGAAFKPTKGAQYEAGIKVDFLDRRLSTTLAAYQIIKENVRTVDPNNPLFSIQVGEQ
CCCCCCCCCCCCCCCEECCEEEEHHHHHHHHHHHHHHHHHHHCCEECCCCCEEEEEECCC
RSQGIELDFAGQVLPGWKIIGSYAYTDGEVTGDNLIPAGNKLRNVPEHQASLWTTYEIPQ
CCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCHHHCEEEEEECCC
GNLKGLGFGLGLFYVGSRAGDLPNTFTLPDYLRTDAKLYYRNSGLNAAINIRNLFDMDYV
CCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCEEEEEHHHHHHHHH
RSSFNNIFLQRGAPLTITCSIGWEL
HHHHHHEEEECCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]