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The map label for this gene is macB [H]

Identifier: 37519914

GI number: 37519914

Start: 359542

End: 360747

Strand: Reverse

Name: macB [H]

Synonym: gll0345

Alternate gene names: 37519914

Gene position: 360747-359542 (Counterclockwise)

Preceding gene: 37519915

Following gene: 37519913

Centisome position: 7.74

GC content: 64.26

Gene sequence:

>1206_bases
ATGTTGCTGATTGAAAGCTTGAGAATGGCCGTCGCCACCCTGGGCGCCAACAAGTTGCGCAGCGGCCTGACGATGCTCGG
TATCGTCATCGGCAACGCCTCGGTGATCGCGATGGTGGGCATCGGCCAGGGCAGCCAGAATTTTATCGCCGGCAAGCTCG
AGGCCTACGGCACCAACCGGATCACCGTATTTACCCAATCGGAAGATCCCGACGGCTACGTCTTTCCGGACTCGAAGCTG
GTGCTCTCCGACGCCGAAGCCGTCCGCACCCAGGTGCCGGCGGTGCGCGCGGTGGCTCCGATTATCGAAGTGCGTTTGCC
GATTTTTCTAGGCAGCCGCCGGACGGCCACCAACGTGCGCGGCACGACGCCGGATTTTGCCCGGGTGCAAAATTTTGCCG
TCGAGCGCGGGCGGCTTTTTTCGCCCGACGAATTGCAGCGCGAGTCCCAGGTAGTGATCCTGGGAGCGACCACGGCGAAC
AAACTGTTCGGCCGCGCCGCGCCCATCGGCCGGGAAGTGACGATCAACAACTTGCCTTTTCGGGTGGTGGGCCTGCTCAA
GCCGAAGGGTTCGTTTGCCGGGGACAACCCGGACGAGACGGCCGTCGTGCCGGTGACGACGATGGCCAATCGGGTGGTGG
GGCGGCGCTCGGCCTACGGCACACCCATCACTTACCTGGAGGCGATGGCGGTCGATTCCACTCAGATCCGCTCTGCCGGT
TTCCAGATGCTCAACGTGCTGGAGCGCCTGCACGGCCGCAAGGACATCATCCTCTCGGCCAACAAGTCCTTTATCGACCT
GGCCAACCAGGTGAGCGGCGCGCTGTCGCTGCTGCTGTCGCTGGTGGCGGCCGTTTCGCTGCTGGTGGGCGGCATCGGGA
TCATGAACATGATGCTCGTCTCGGTAGGTGAGCGCACCCAGGAAATTGGTTTGCGCAAAGCGATCGGCGCCAAGCAGCGG
GACATTCTCAGCCAGTTTTTGTTCGAGGCTGTCCTCCTTTCGGCGGCAGGCGGATTGGCGGGCATCGCCGTGGGCATCGG
CGCAACGTTGCCGCTCGCCTGGTTCACCCCGATCCGGCCTCTGATTCCGTGGAGCGCCGTGCTGCTCGCGGTTGGGGTCT
CAGGCACCATCGGTCTGGTGTTCGGCGTCTTTCCGGCGCGGCAGGCCGCCCGCCTCGACCCGATCGCGGCCTTGCGCAGC
AGTTGA

Upstream 100 bases:

>100_bases
AGTTCAGATCCTCGAAGGTCTGCGGCCCGGCGAGCGCGTCTTTTTGCAACCGCCCCCGGAGGTGGTCGTCGAAGGTGTCG
ATACGCTGGTGTGGTAAGCG

Downstream 100 bases:

>100_bases
TGGATTGCCACCGGAGGATAGACGTTGCCGGCTATGTTTGCCACGCCGGTGACCGTACTTCATCCCATTGTCCCACACCG
GGTTTGCTACCCTTGGGACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLLIESLRMAVATLGANKLRSGLTMLGIVIGNASVIAMVGIGQGSQNFIAGKLEAYGTNRITVFTQSEDPDGYVFPDSKL
VLSDAEAVRTQVPAVRAVAPIIEVRLPIFLGSRRTATNVRGTTPDFARVQNFAVERGRLFSPDELQRESQVVILGATTAN
KLFGRAAPIGREVTINNLPFRVVGLLKPKGSFAGDNPDETAVVPVTTMANRVVGRRSAYGTPITYLEAMAVDSTQIRSAG
FQMLNVLERLHGRKDIILSANKSFIDLANQVSGALSLLLSLVAAVSLLVGGIGIMNMMLVSVGERTQEIGLRKAIGAKQR
DILSQFLFEAVLLSAAGGLAGIAVGIGATLPLAWFTPIRPLIPWSAVLLAVGVSGTIGLVFGVFPARQAARLDPIAALRS
S

Sequences:

>Translated_401_residues
MLLIESLRMAVATLGANKLRSGLTMLGIVIGNASVIAMVGIGQGSQNFIAGKLEAYGTNRITVFTQSEDPDGYVFPDSKL
VLSDAEAVRTQVPAVRAVAPIIEVRLPIFLGSRRTATNVRGTTPDFARVQNFAVERGRLFSPDELQRESQVVILGATTAN
KLFGRAAPIGREVTINNLPFRVVGLLKPKGSFAGDNPDETAVVPVTTMANRVVGRRSAYGTPITYLEAMAVDSTQIRSAG
FQMLNVLERLHGRKDIILSANKSFIDLANQVSGALSLLLSLVAAVSLLVGGIGIMNMMLVSVGERTQEIGLRKAIGAKQR
DILSQFLFEAVLLSAAGGLAGIAVGIGATLPLAWFTPIRPLIPWSAVLLAVGVSGTIGLVFGVFPARQAARLDPIAALRS
S
>Mature_401_residues
MLLIESLRMAVATLGANKLRSGLTMLGIVIGNASVIAMVGIGQGSQNFIAGKLEAYGTNRITVFTQSEDPDGYVFPDSKL
VLSDAEAVRTQVPAVRAVAPIIEVRLPIFLGSRRTATNVRGTTPDFARVQNFAVERGRLFSPDELQRESQVVILGATTAN
KLFGRAAPIGREVTINNLPFRVVGLLKPKGSFAGDNPDETAVVPVTTMANRVVGRRSAYGTPITYLEAMAVDSTQIRSAG
FQMLNVLERLHGRKDIILSANKSFIDLANQVSGALSLLLSLVAAVSLLVGGIGIMNMMLVSVGERTQEIGLRKAIGAKQR
DILSQFLFEAVLLSAAGGLAGIAVGIGATLPLAWFTPIRPLIPWSAVLLAVGVSGTIGLVFGVFPARQAARLDPIAALRS
S

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=400, Percent_Identity=36, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42397; Mature: 42397

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIESLRMAVATLGANKLRSGLTMLGIVIGNASVIAMVGIGQGSQNFIAGKLEAYGTNR
CEEHHHHHHHHHHHCHHHHHCCHHEEEHEECCCEEEEEEECCCCCCCEEEEEHEECCCCE
ITVFTQSEDPDGYVFPDSKLVLSDAEAVRTQVPAVRAVAPIIEVRLPIFLGSRRTATNVR
EEEEECCCCCCCEECCCCCEEECCHHHHHHHCCHHHHHHHHHHHEEHEEECCCCCCCCCC
GTTPDFARVQNFAVERGRLFSPDELQRESQVVILGATTANKLFGRAAPIGREVTINNLPF
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECHHHHHHHCCCCCCCEEEECCCCE
RVVGLLKPKGSFAGDNPDETAVVPVTTMANRVVGRRSAYGTPITYLEAMAVDSTQIRSAG
EEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
FQMLNVLERLHGRKDIILSANKSFIDLANQVSGALSLLLSLVAAVSLLVGGIGIMNMMLV
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGERTQEIGLRKAIGAKQRDILSQFLFEAVLLSAAGGLAGIAVGIGATLPLAWFTPIRP
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCH
LIPWSAVLLAVGVSGTIGLVFGVFPARQAARLDPIAALRSS
HCCHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCHHHHHHCC
>Mature Secondary Structure
MLLIESLRMAVATLGANKLRSGLTMLGIVIGNASVIAMVGIGQGSQNFIAGKLEAYGTNR
CEEHHHHHHHHHHHCHHHHHCCHHEEEHEECCCEEEEEEECCCCCCCEEEEEHEECCCCE
ITVFTQSEDPDGYVFPDSKLVLSDAEAVRTQVPAVRAVAPIIEVRLPIFLGSRRTATNVR
EEEEECCCCCCCEECCCCCEEECCHHHHHHHCCHHHHHHHHHHHEEHEEECCCCCCCCCC
GTTPDFARVQNFAVERGRLFSPDELQRESQVVILGATTANKLFGRAAPIGREVTINNLPF
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEEECHHHHHHHCCCCCCCEEEECCCCE
RVVGLLKPKGSFAGDNPDETAVVPVTTMANRVVGRRSAYGTPITYLEAMAVDSTQIRSAG
EEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHH
FQMLNVLERLHGRKDIILSANKSFIDLANQVSGALSLLLSLVAAVSLLVGGIGIMNMMLV
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVGERTQEIGLRKAIGAKQRDILSQFLFEAVLLSAAGGLAGIAVGIGATLPLAWFTPIRP
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCH
LIPWSAVLLAVGVSGTIGLVFGVFPARQAARLDPIAALRSS
HCCHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA