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The map label for this gene is mreD [H]

Identifier: 34499814

GI number: 34499814

Start: 4699821

End: 4700324

Strand: Direct

Name: mreD [H]

Synonym: CV_4359

Alternate gene names: 34499814

Gene position: 4699821-4700324 (Clockwise)

Preceding gene: 34499813

Following gene: 34499815

Centisome position: 98.92

GC content: 65.28

Gene sequence:

>504_bases
ATGTCGTTGGACCGTCCCAAGGAACTGCTCAAGCCGGTCAAGCGCCGCTTCATCCTGACCACCTTCGTGATCGCCGTGCT
GATCGAGCTGGTGCCGCTGCCGCACGGCAGCACGCGCTGGCTGCCCGACTTCATCGGCCTCCTGATCCTGTACTGGGTGA
TCAACCAGCCGCGCCGCGTCAACATCGGCATCGCCTTCCTGATGGGCATCATCGCCGACGTGTCCACCGCCGGCCTGTTC
GGCCAGCACGCGCTGGCCTACTCGGTGACCGCCTTCCTGGCCTTGAGCCGCCAGCGCCAGCTGGTGATGTTCAACCTGGG
CCAGCAGGCGCTGGTGGTGCTGGGCCTGATGCTGACCAACCAGTTGATCATGGTGGTGGTGCGGATGCTGACCGGCTCCG
CCTTCGTCGGCTGGAGCTACTTCCTGCCGCCCCTGATTGGCGCGCTGCTGTGGCCGCTGCTGACCAAGCTGATGCTGATC
CCCTACCGCCAACACACGGCATGA

Upstream 100 bases:

>100_bases
GCAGGCCAAGGAAACGCGCCCGCGCCCGGCGGAACCGCCGCCGCTGCCGGAGAAGAAGACCAAGGGCGGCAAGAAGTCCG
CCGACGAGGAGTAAGCCCAG

Downstream 100 bases:

>100_bases
AACTCGACTGACCCATGCGCCGCCCGTCCCGTTTCAAGAACCCGCAGTCCGAAGAGGCCCAGTTCGAGCTGCGGCTGGTC
ATCGCCTACGCGCTGATCAT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSLDRPKELLKPVKRRFILTTFVIAVLIELVPLPHGSTRWLPDFIGLLILYWVINQPRRVNIGIAFLMGIIADVSTAGLF
GQHALAYSVTAFLALSRQRQLVMFNLGQQALVVLGLMLTNQLIMVVVRMLTGSAFVGWSYFLPPLIGALLWPLLTKLMLI
PYRQHTA

Sequences:

>Translated_167_residues
MSLDRPKELLKPVKRRFILTTFVIAVLIELVPLPHGSTRWLPDFIGLLILYWVINQPRRVNIGIAFLMGIIADVSTAGLF
GQHALAYSVTAFLALSRQRQLVMFNLGQQALVVLGLMLTNQLIMVVVRMLTGSAFVGWSYFLPPLIGALLWPLLTKLMLI
PYRQHTA
>Mature_166_residues
SLDRPKELLKPVKRRFILTTFVIAVLIELVPLPHGSTRWLPDFIGLLILYWVINQPRRVNIGIAFLMGIIADVSTAGLFG
QHALAYSVTAFLALSRQRQLVMFNLGQQALVVLGLMLTNQLIMVVVRMLTGSAFVGWSYFLPPLIGALLWPLLTKLMLIP
YRQHTA

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18780; Mature: 18649

Theoretical pI: Translated: 11.48; Mature: 11.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDRPKELLKPVKRRFILTTFVIAVLIELVPLPHGSTRWLPDFIGLLILYWVINQPRRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
NIGIAFLMGIIADVSTAGLFGQHALAYSVTAFLALSRQRQLVMFNLGQQALVVLGLMLTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHH
QLIMVVVRMLTGSAFVGWSYFLPPLIGALLWPLLTKLMLIPYRQHTA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SLDRPKELLKPVKRRFILTTFVIAVLIELVPLPHGSTRWLPDFIGLLILYWVINQPRRV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEE
NIGIAFLMGIIADVSTAGLFGQHALAYSVTAFLALSRQRQLVMFNLGQQALVVLGLMLTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHH
QLIMVVVRMLTGSAFVGWSYFLPPLIGALLWPLLTKLMLIPYRQHTA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]