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The map label for this gene is murG

Identifier: 34499798

GI number: 34499798

Start: 4682667

End: 4683749

Strand: Reverse

Name: murG

Synonym: CV_4343

Alternate gene names: 34499798

Gene position: 4683749-4682667 (Counterclockwise)

Preceding gene: 34499799

Following gene: 34499797

Centisome position: 98.58

GC content: 71.28

Gene sequence:

>1083_bases
ATGGCGAATCGCACGGTCATGGTGATGGCGGCTGGCACGGGCGGACACATCGTCCCCGGCCTCGCCGTGGCCAAGGAATT
GCAAAGCCGCGGCTGGAAGGTGGTGTGGCTGGGCACCCGCCGCGGCATGGAGAACAAGCTGGTGCCGCCGACCGGCATCC
CGCTGGAGAGGCTGAATTTCCACGGCGTGCGCGGCAAGGGCCTGCTGGGCTCGCTCAAGGGCGCGCTGCAGTTGGCCGGC
GCTTTCTTCAGCAGCGCGGCGCAGATCTTCCGCCACCGGCCGGACGTGGTGCTGGGCATGGGCGGCTACGTCTGCCTGCC
CGGCGGCGTGATGGCCGGCCTGCTGTGGAAGCCGCTGGTGCTGGTCAACGCCGACGCCGGCCTGCTGCTCAGCAACAAGG
CTTTGCTGCCGTTCGCCAGCAAGCTGGTTTGCGGTTTCGACGGCAGCGCGGCGCGTGGCCCCAAGGCGCTGGTCACCGGC
AATCCGGTGCGCGGCGAGATCGAGCGCATCGCCGCGCCGGCGGCGCGCTTCGCCGGCCGCAGCGGTCCGCTGAAGGTATT
GGTGGTCGGCGGCAGCCTGGGCGCCAAGGTGTTGAACGAAACGCTGCCGCAGGCGATGGCCAGGCTGCCGGCCGAGCAGC
GGCCGCAGCTGACGCATCAGACCGGCGAGGCGAATTTCGCCGCGGTCGAGGCCGCCTATCAGGCGGCGGGCCTGCGGCAG
CAAGTGGAGCTGCTGCCCTTCGTCGACGATATGCCGAAGCGGCTGGCCGAGTGCGATCTGGTGATCTGCCGCGCCGGCGC
GATCACGGTCAGCGAATTGTGCGCGGCCGGCGTGCCCAGCGTGCTGGTGCCGCTGGTGGTGTCCACCACCAGCCACCAGC
GCGACAACGCCGAGTGGATGGCCCAGGCCGGCGCGGCCTGGCATCTGCCGCAGAAGGAATTGAACGCCGACGGGCTCGCG
GGCCTGCTGGCGGGTTTGGACAGAGACCAGTTGCTGGACAAGGCCGAGCGCGCCCGCGCGCTGGCCCGCTCCGGCGCGGC
CGGCCGGGTGGCCGACCTGTGCCAGCAGCTGGCCGGGGAATGA

Upstream 100 bases:

>100_bases
GCGGTTCGGCGATGCTGATGAATTTGATCGCGGTGGCGGTGCTGCTGCGGGTTGATTATGAGAACCGGCGCATCATGCGC
GGGTACAAGGTTTGAGAGAA

Downstream 100 bases:

>100_bases
CAGGGCGCCGAGCGAGCGTCCAAGCAGAGACACAGACATGAAACACAGGGTCAAACACATACATTTCGTGGGCATAGGCG
GCGTCGGCATGTGCGGCATC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MANRTVMVMAAGTGGHIVPGLAVAKELQSRGWKVVWLGTRRGMENKLVPPTGIPLERLNFHGVRGKGLLGSLKGALQLAG
AFFSSAAQIFRHRPDVVLGMGGYVCLPGGVMAGLLWKPLVLVNADAGLLLSNKALLPFASKLVCGFDGSAARGPKALVTG
NPVRGEIERIAAPAARFAGRSGPLKVLVVGGSLGAKVLNETLPQAMARLPAEQRPQLTHQTGEANFAAVEAAYQAAGLRQ
QVELLPFVDDMPKRLAECDLVICRAGAITVSELCAAGVPSVLVPLVVSTTSHQRDNAEWMAQAGAAWHLPQKELNADGLA
GLLAGLDRDQLLDKAERARALARSGAAGRVADLCQQLAGE

Sequences:

>Translated_360_residues
MANRTVMVMAAGTGGHIVPGLAVAKELQSRGWKVVWLGTRRGMENKLVPPTGIPLERLNFHGVRGKGLLGSLKGALQLAG
AFFSSAAQIFRHRPDVVLGMGGYVCLPGGVMAGLLWKPLVLVNADAGLLLSNKALLPFASKLVCGFDGSAARGPKALVTG
NPVRGEIERIAAPAARFAGRSGPLKVLVVGGSLGAKVLNETLPQAMARLPAEQRPQLTHQTGEANFAAVEAAYQAAGLRQ
QVELLPFVDDMPKRLAECDLVICRAGAITVSELCAAGVPSVLVPLVVSTTSHQRDNAEWMAQAGAAWHLPQKELNADGLA
GLLAGLDRDQLLDKAERARALARSGAAGRVADLCQQLAGE
>Mature_359_residues
ANRTVMVMAAGTGGHIVPGLAVAKELQSRGWKVVWLGTRRGMENKLVPPTGIPLERLNFHGVRGKGLLGSLKGALQLAGA
FFSSAAQIFRHRPDVVLGMGGYVCLPGGVMAGLLWKPLVLVNADAGLLLSNKALLPFASKLVCGFDGSAARGPKALVTGN
PVRGEIERIAAPAARFAGRSGPLKVLVVGGSLGAKVLNETLPQAMARLPAEQRPQLTHQTGEANFAAVEAAYQAAGLRQQ
VELLPFVDDMPKRLAECDLVICRAGAITVSELCAAGVPSVLVPLVVSTTSHQRDNAEWMAQAGAAWHLPQKELNADGLAG
LLAGLDRDQLLDKAERARALARSGAAGRVADLCQQLAGE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=355, Percent_Identity=43.6619718309859, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CHRVO (Q7NPZ9)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_904013.1
- ProteinModelPortal:   Q7NPZ9
- SMR:   Q7NPZ9
- GeneID:   2549702
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_4343
- NMPDR:   fig|243365.1.peg.4343
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q7NPZ9
- ProtClustDB:   PRK00726
- BioCyc:   CVIO243365:CV_4343-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37605; Mature: 37474

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRTVMVMAAGTGGHIVPGLAVAKELQSRGWKVVWLGTRRGMENKLVPPTGIPLERLNF
CCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHCCC
HGVRGKGLLGSLKGALQLAGAFFSSAAQIFRHRPDVVLGMGGYVCLPGGVMAGLLWKPLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHHHHHCCEE
LVNADAGLLLSNKALLPFASKLVCGFDGSAARGPKALVTGNPVRGEIERIAAPAARFAGR
EEECCCCEEEECCCCCHHHHHHEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
SGPLKVLVVGGSLGAKVLNETLPQAMARLPAEQRPQLTHQTGEANFAAVEAAYQAAGLRQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QVELLPFVDDMPKRLAECDLVICRAGAITVSELCAAGVPSVLVPLVVSTTSHQRDNAEWM
HHHHHCCHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHH
AQAGAAWHLPQKELNADGLAGLLAGLDRDQLLDKAERARALARSGAAGRVADLCQQLAGE
HHCCCEECCCHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
ANRTVMVMAAGTGGHIVPGLAVAKELQSRGWKVVWLGTRRGMENKLVPPTGIPLERLNF
CCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHCCC
HGVRGKGLLGSLKGALQLAGAFFSSAAQIFRHRPDVVLGMGGYVCLPGGVMAGLLWKPLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCHHHHHHHHHCCEE
LVNADAGLLLSNKALLPFASKLVCGFDGSAARGPKALVTGNPVRGEIERIAAPAARFAGR
EEECCCCEEEECCCCCHHHHHHEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
SGPLKVLVVGGSLGAKVLNETLPQAMARLPAEQRPQLTHQTGEANFAAVEAAYQAAGLRQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QVELLPFVDDMPKRLAECDLVICRAGAITVSELCAAGVPSVLVPLVVSTTSHQRDNAEWM
HHHHHCCHHHHHHHHHHCCEEEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHH
AQAGAAWHLPQKELNADGLAGLLAGLDRDQLLDKAERARALARSGAAGRVADLCQQLAGE
HHCCCEECCCHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782