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The map label for this gene is htpX2 [H]

Identifier: 34499718

GI number: 34499718

Start: 4597535

End: 4598389

Strand: Reverse

Name: htpX2 [H]

Synonym: CV_4263

Alternate gene names: 34499718

Gene position: 4598389-4597535 (Counterclockwise)

Preceding gene: 34499719

Following gene: 34499717

Centisome position: 96.79

GC content: 67.49

Gene sequence:

>855_bases
ATGAACGACAACTGGCTGAAGACCACGATGCTGATGGCCGCCATCATGGCGCTGTTCGTCCTGATAGGCGGCATGCTGGG
CGGCAAGGGCGGCATGCTGCTGGCGCTGCTGTTCGGCGGCGGCATGAACTTGTTCGCCTGGTGGAATTCCGACCGCATGG
TGCTGTCGATGTACAACGCGCAGGAAGTGGACGCCAACAGCGCGCCCGAATTCTACGGCATGGTGGCCGAGCTGGCGCAG
CGCGCCGGCCTGCCGATGCCGCGCGTCTACGTGATCCACGAGGACCAGCCCAACGCCTTCGCCACCGGGCGCAACCCGGA
AAACGCGGCGGTGGCGGCCACCAGCGGCATCATGCGCATGCTCGACTACCGCGAGCTGCGCGGCGTGATGGCCCACGAGC
TGGCCCACGTCAAGCACCGCGACACCCTGATCTCCACTATCTCGGCGACGATGGCCGGCGCCATTTCCGCGCTGGCCAAC
TTCGCGATGTTCTTCGGCGGCCGCGACGAGAACGGCCAGCCGGTCGGCCTGCTGCCGCGGCTGGCGGTGGCTTTCCTCGC
CCCGGTGGCGGCCAGCCTGATCCAGATGGCGATCTCGCGCGCGCGCGAGTTCGAGGCCGACCGCGGCGGGGCCGAGATTT
GCGGCGATCCGCTGGCGCTGGCTTCCGCGCTGCAGAAAATCGAATATTATGCCCAGGGCATCTCGATGCCGTCCGCCGAG
GCGCATCCGGAGACCGCGCAGATGATGATCATTAATCCCTTGTCCGGCGGCGGCGTGGGCGATCTGTTCCGCACCCATCC
GCATACCGCCGATCGCATAGAGCGGCTGCAGGCGCTGGCGCGCGGCGTCTACTAG

Upstream 100 bases:

>100_bases
CGCCCGCGATTTCGTCGCCGGCAAGAGCCTGCCGGCGGGAACCCGTCTGGGCGTTTGACGCACTAAGTTTCAGGCAAACC
CGCAGTTTCGAGAGGAGAGC

Downstream 100 bases:

>100_bases
CGCAGGCCCTTGAACCGACCCGCGGCCAGTCCCCCGGACTGGCCTTGTTTTATCGAAAGACACACCATGTATCAAATCCA
GCAACTGGCCGCCGAGATCC

Product: M48 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNDNWLKTTMLMAAIMALFVLIGGMLGGKGGMLLALLFGGGMNLFAWWNSDRMVLSMYNAQEVDANSAPEFYGMVAELAQ
RAGLPMPRVYVIHEDQPNAFATGRNPENAAVAATSGIMRMLDYRELRGVMAHELAHVKHRDTLISTISATMAGAISALAN
FAMFFGGRDENGQPVGLLPRLAVAFLAPVAASLIQMAISRAREFEADRGGAEICGDPLALASALQKIEYYAQGISMPSAE
AHPETAQMMIINPLSGGGVGDLFRTHPHTADRIERLQALARGVY

Sequences:

>Translated_284_residues
MNDNWLKTTMLMAAIMALFVLIGGMLGGKGGMLLALLFGGGMNLFAWWNSDRMVLSMYNAQEVDANSAPEFYGMVAELAQ
RAGLPMPRVYVIHEDQPNAFATGRNPENAAVAATSGIMRMLDYRELRGVMAHELAHVKHRDTLISTISATMAGAISALAN
FAMFFGGRDENGQPVGLLPRLAVAFLAPVAASLIQMAISRAREFEADRGGAEICGDPLALASALQKIEYYAQGISMPSAE
AHPETAQMMIINPLSGGGVGDLFRTHPHTADRIERLQALARGVY
>Mature_284_residues
MNDNWLKTTMLMAAIMALFVLIGGMLGGKGGMLLALLFGGGMNLFAWWNSDRMVLSMYNAQEVDANSAPEFYGMVAELAQ
RAGLPMPRVYVIHEDQPNAFATGRNPENAAVAATSGIMRMLDYRELRGVMAHELAHVKHRDTLISTISATMAGAISALAN
FAMFFGGRDENGQPVGLLPRLAVAFLAPVAASLIQMAISRAREFEADRGGAEICGDPLALASALQKIEYYAQGISMPSAE
AHPETAQMMIINPLSGGGVGDLFRTHPHTADRIERLQALARGVY

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=287, Percent_Identity=32.404181184669, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30529; Mature: 30529

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNWLKTTMLMAAIMALFVLIGGMLGGKGGMLLALLFGGGMNLFAWWNSDRMVLSMYNA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEECCC
QEVDANSAPEFYGMVAELAQRAGLPMPRVYVIHEDQPNAFATGRNPENAAVAATSGIMRM
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHH
LDYRELRGVMAHELAHVKHRDTLISTISATMAGAISALANFAMFFGGRDENGQPVGLLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LAVAFLAPVAASLIQMAISRAREFEADRGGAEICGDPLALASALQKIEYYAQGISMPSAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
AHPETAQMMIINPLSGGGVGDLFRTHPHTADRIERLQALARGVY
CCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDNWLKTTMLMAAIMALFVLIGGMLGGKGGMLLALLFGGGMNLFAWWNSDRMVLSMYNA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCEEEEECCC
QEVDANSAPEFYGMVAELAQRAGLPMPRVYVIHEDQPNAFATGRNPENAAVAATSGIMRM
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCHHHHHHHHHHHH
LDYRELRGVMAHELAHVKHRDTLISTISATMAGAISALANFAMFFGGRDENGQPVGLLPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LAVAFLAPVAASLIQMAISRAREFEADRGGAEICGDPLALASALQKIEYYAQGISMPSAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
AHPETAQMMIINPLSGGGVGDLFRTHPHTADRIERLQALARGVY
CCCCCCEEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA