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The map label for this gene is pilE2 [H]

Identifier: 34499664

GI number: 34499664

Start: 4542652

End: 4543119

Strand: Reverse

Name: pilE2 [H]

Synonym: CV_4209

Alternate gene names: 34499664

Gene position: 4543119-4542652 (Counterclockwise)

Preceding gene: 34499669

Following gene: 34499663

Centisome position: 95.62

GC content: 60.68

Gene sequence:

>468_bases
ATGAAGAAACAGCGTAAACAGCAGGGCTTCACCCTGATCGAACTGATGATCGTGGTCGCCATCGTCGGCATCCTGGCCGC
CATCGCCATTCCGGCCTATCAGGACTACACCAAGCGCGCGCGGGTGTCGGAAGGGTTGGCGCTGGCCGACGCGGCCAAGA
CGGCGGTGACCGAATACTACGCGACCAACAACGCGTGGGCCTCCGGCACCGCGCCTTTTAACACGACTTACGGATTGGCG
GCGTCCATTACGGGTAACTCGGTGAGCAGCATCAACGTTCTGGCGAACGGGGTGGTCCAGATCGCTTACAATTCGACAGT
ATCGAATGGTGCGTTGGTCGATCTGGTGCCGACCGTCAGCGCGGGCTCGGTGCAGTGGTACTGCACCTATACCGGCTCCG
GCACAACGGCCATCGCATCTGCTAGCCAACTGAGCGCCAACTGGGTGCCATCCACTTGCCGTCAGTAA

Upstream 100 bases:

>100_bases
CACGACGGGAAGACCCCGCGATCTTTAGAAGATGAGACGGAGAGGCGTGGGAACGCGCCGCGCTCCACCTTGGCTAAGCT
TGGCTCACTGGGAGTTCAAC

Downstream 100 bases:

>100_bases
GTCAACGGGCTGGTGTGTGAACAGGGGGCATCTCGGTGCCTCCTTTATTTTTGATGCGAAAGGTATGATAGGCCGAGACC
AGTATAATCATGTCGGAACA

Product: type IV pilin

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKKQRKQQGFTLIELMIVVAIVGILAAIAIPAYQDYTKRARVSEGLALADAAKTAVTEYYATNNAWASGTAPFNTTYGLA
ASITGNSVSSINVLANGVVQIAYNSTVSNGALVDLVPTVSAGSVQWYCTYTGSGTTAIASASQLSANWVPSTCRQ

Sequences:

>Translated_155_residues
MKKQRKQQGFTLIELMIVVAIVGILAAIAIPAYQDYTKRARVSEGLALADAAKTAVTEYYATNNAWASGTAPFNTTYGLA
ASITGNSVSSINVLANGVVQIAYNSTVSNGALVDLVPTVSAGSVQWYCTYTGSGTTAIASASQLSANWVPSTCRQ
>Mature_155_residues
MKKQRKQQGFTLIELMIVVAIVGILAAIAIPAYQDYTKRARVSEGLALADAAKTAVTEYYATNNAWASGTAPFNTTYGLA
ASITGNSVSSINVLANGVVQIAYNSTVSNGALVDLVPTVSAGSVQWYCTYTGSGTTAIASASQLSANWVPSTCRQ

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=112, Percent_Identity=36.6071428571429, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 16162; Mature: 16162

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQRKQQGFTLIELMIVVAIVGILAAIAIPAYQDYTKRARVSEGLALADAAKTAVTEYY
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ATNNAWASGTAPFNTTYGLAASITGNSVSSINVLANGVVQIAYNSTVSNGALVDLVPTVS
HCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHEECCCEEEEEECCCCCCCEEEEEECCCC
AGSVQWYCTYTGSGTTAIASASQLSANWVPSTCRQ
CCCEEEEEEECCCCCEEEHHHHHCCCCCCCHHCCC
>Mature Secondary Structure
MKKQRKQQGFTLIELMIVVAIVGILAAIAIPAYQDYTKRARVSEGLALADAAKTAVTEYY
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ATNNAWASGTAPFNTTYGLAASITGNSVSSINVLANGVVQIAYNSTVSNGALVDLVPTVS
HCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHEECCCEEEEEECCCCCCCEEEEEECCCC
AGSVQWYCTYTGSGTTAIASASQLSANWVPSTCRQ
CCCEEEEEEECCCCCEEEHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]