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The map label for this gene is corC [H]

Identifier: 34499608

GI number: 34499608

Start: 4493191

End: 4494042

Strand: Direct

Name: corC [H]

Synonym: CV_4153

Alternate gene names: 34499608

Gene position: 4493191-4494042 (Clockwise)

Preceding gene: 34499607

Following gene: 34499609

Centisome position: 94.57

GC content: 64.08

Gene sequence:

>852_bases
ATGGAAGACCCCAGTAAACCGCGACCCAGTTGGCTTGAACGCCTGTCCACCATGCTCTTGCGCGAGCCGGAAGACCGCGA
GGAGTTGATCGAGCTGTTGCACAACGCCTTCGAGCGCAACCTGCTCGACGCCGAGGCCCTCGGCATGATCGAAGGCGTGC
TGGAGGTCAGCGAGCTGACCGTGCGCGACGTGATGATCCCGCGCAGCCAGATGCACGTGCTGAACATCGACGACCCCATC
GCCCGCTTCCTGCCGACCGTGATCGACTCCGGCCACTCGCGCTTCCCGGTGATAGGCGAGAGCAAGGATGACGTGCAAGG
CATCCTGCTGGCCAAGGAGTTGCTGCGTTACTTCCATGCGCCCTCCACCTTCAATCTGAAGAACGTGCTGCGCCCGGCGG
TGTTCGTGCCGGAGTCCAAGCCGCTGAACGTGCTGCTGCGCGACTTCCGCGCCACCCACAACCACATGGCGGTGGTGGTG
GACGAATACGGCGGCGTCTGCGGCCTGGTGACCATCGAAGACGTGATCGAGCAGATCGTCGGCGACATCGAGGACGAGTA
CGACATCGACGACGACGAGGACGACATCGTGCCGGTGCGCGGCAACGAGCGTTACCGCGTCAAGGCGCTGACCGAAATCG
AAGACTTCAACCACTACTTCGGCACCGACTACGCCGACGACGACGTCGACACCGTCGGCGGCCTGGTGATCTCGCTGACC
GGCCACCTGCCCAAGCGCGGCGAGAAAATAGAGGCCGCCGGCCTGCGCTTCACCGTGCTGCGCGCCGACAGCCGCCGCCT
GGACACCTTGCTGGTGGAACGCATCCAGGCCTCCATCGACATCGCCGAATAA

Upstream 100 bases:

>100_bases
TGAAGAGGACGCAGAGGCCGAAGCGATGGAAGTGCTTGAAACCGTAATCGTTAAACAGCTAGGATATCCCGATCCCTACC
ACGAGGAGCACATCTAAGAA

Downstream 100 bases:

>100_bases
GGCTATGCTGAATGCAGCCGGCGGCGCCGGCTGCGATCCTTCGTCCCCAACTGCAACAAGCCCCATGCGAATCCTGATCC
TGCTCTTGGCCGCCGCGCTG

Product: magnesium and cobalt efflux protein corC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MEDPSKPRPSWLERLSTMLLREPEDREELIELLHNAFERNLLDAEALGMIEGVLEVSELTVRDVMIPRSQMHVLNIDDPI
ARFLPTVIDSGHSRFPVIGESKDDVQGILLAKELLRYFHAPSTFNLKNVLRPAVFVPESKPLNVLLRDFRATHNHMAVVV
DEYGGVCGLVTIEDVIEQIVGDIEDEYDIDDDEDDIVPVRGNERYRVKALTEIEDFNHYFGTDYADDDVDTVGGLVISLT
GHLPKRGEKIEAAGLRFTVLRADSRRLDTLLVERIQASIDIAE

Sequences:

>Translated_283_residues
MEDPSKPRPSWLERLSTMLLREPEDREELIELLHNAFERNLLDAEALGMIEGVLEVSELTVRDVMIPRSQMHVLNIDDPI
ARFLPTVIDSGHSRFPVIGESKDDVQGILLAKELLRYFHAPSTFNLKNVLRPAVFVPESKPLNVLLRDFRATHNHMAVVV
DEYGGVCGLVTIEDVIEQIVGDIEDEYDIDDDEDDIVPVRGNERYRVKALTEIEDFNHYFGTDYADDDVDTVGGLVISLT
GHLPKRGEKIEAAGLRFTVLRADSRRLDTLLVERIQASIDIAE
>Mature_283_residues
MEDPSKPRPSWLERLSTMLLREPEDREELIELLHNAFERNLLDAEALGMIEGVLEVSELTVRDVMIPRSQMHVLNIDDPI
ARFLPTVIDSGHSRFPVIGESKDDVQGILLAKELLRYFHAPSTFNLKNVLRPAVFVPESKPLNVLLRDFRATHNHMAVVV
DEYGGVCGLVTIEDVIEQIVGDIEDEYDIDDDEDDIVPVRGNERYRVKALTEIEDFNHYFGTDYADDDVDTVGGLVISLT
GHLPKRGEKIEAAGLRFTVLRADSRRLDTLLVERIQASIDIAE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=207, Percent_Identity=28.9855072463768, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI94681046, Length=188, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40068055, Length=214, Percent_Identity=29.4392523364486, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40068053, Length=214, Percent_Identity=29.4392523364486, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=47.6377952755905, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI145693175, Length=229, Percent_Identity=28.82096069869, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788119, Length=235, Percent_Identity=31.4893617021277, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790664, Length=233, Percent_Identity=27.8969957081545, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082033, Length=222, Percent_Identity=27.4774774774775, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32026; Mature: 32026

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPSKPRPSWLERLSTMLLREPEDREELIELLHNAFERNLLDAEALGMIEGVLEVSELT
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VRDVMIPRSQMHVLNIDDPIARFLPTVIDSGHSRFPVIGESKDDVQGILLAKELLRYFHA
HHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSTFNLKNVLRPAVFVPESKPLNVLLRDFRATHNHMAVVVDEYGGVCGLVTIEDVIEQIV
CCCCCHHHHHCCCEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHH
GDIEDEYDIDDDEDDIVPVRGNERYRVKALTEIEDFNHYFGTDYADDDVDTVGGLVISLT
HCCCCCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEE
GHLPKRGEKIEAAGLRFTVLRADSRRLDTLLVERIQASIDIAE
CCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEDPSKPRPSWLERLSTMLLREPEDREELIELLHNAFERNLLDAEALGMIEGVLEVSELT
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VRDVMIPRSQMHVLNIDDPIARFLPTVIDSGHSRFPVIGESKDDVQGILLAKELLRYFHA
HHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
PSTFNLKNVLRPAVFVPESKPLNVLLRDFRATHNHMAVVVDEYGGVCGLVTIEDVIEQIV
CCCCCHHHHHCCCEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHH
GDIEDEYDIDDDEDDIVPVRGNERYRVKALTEIEDFNHYFGTDYADDDVDTVGGLVISLT
HCCCCCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHEEEEEE
GHLPKRGEKIEAAGLRFTVLRADSRRLDTLLVERIQASIDIAE
CCCCCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]