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The map label for this gene is lnt

Identifier: 34499609

GI number: 34499609

Start: 4494047

End: 4495597

Strand: Direct

Name: lnt

Synonym: CV_4154

Alternate gene names: 34499609

Gene position: 4494047-4495597 (Clockwise)

Preceding gene: 34499608

Following gene: 34499612

Centisome position: 94.59

GC content: 68.79

Gene sequence:

>1551_bases
ATGCTGAATGCAGCCGGCGGCGCCGGCTGCGATCCTTCGTCCCCAACTGCAACAAGCCCCATGCGAATCCTGATCCTGCT
CTTGGCCGCCGCGCTGGCTGGCGCCTTCACCCTGTTTGCCTTCGCCCCCTACCGGCTGTTCTGGCTGATGCCGCTCTGCC
TGGCCGCGCTGGTCGAACTGCTGCAGCGCGAGCCGCGGCGCGCGTTCTGGCTGGGCTATGCCTGGGGCCTGGGCGCCTAT
GTCAGCAATTTCCGCTGGATCTACGACAGCCTGCACGACGTGGCCGGCCTGCCGGCCTGGATCGCCGCGCCGCTGGTGCT
GCTGCTGCCGGCCTACCTGGCGCTGTATCCCGGCCTGGCGTCCTGGCTGGCCTGCCGCATCGATCCGCGGCCCGGCGTGC
GCTGGCTGCTGGCCTTTCCCGCGGCCTGGGAGCTGGGCGAATGGCTGCGCGGCTGGGTGATGACCGGCTTCCCCTGGGGC
GCCGCCGGTTATTCGCAGATCACCGAAAGCCCACTGGCCGGCTACGCGCCGCTGGGCGGCATCCACCTGGTCAATTACCT
GGTGGCGCTGTCCGCCGCCGCCCTGGCCATGCTTGCGCGCGCCGGCATGCGGCAGCGGATCGGCATCCTGATCGCCGCCG
CGCTGGCATGGGGCAGCGGCGTCTGGCTGCGCGACATCGAATGGACCACGCCGGCGGGCAAGCCGATCACGGTGGCGCTG
GCCCAGGGCAATATCGCGCAAGAACTGAAATGGTCGCCGGAGAACCTGGAAAACTCGCTGCTCACCTATTACCGCCAGGT
GGCGATGACCCGCGCCGACCTGATGATCCTGCCGGAAACCGCGCTGCCGCTGTTCCTCGACGATCTGCCGTCCGGCTATC
TGTCGATGATGCGCGGCGAGGCGTCCCGCGCCGGCATGGCGCTGGCCAGCGGCATCCCGCGCCGCACCGACGACGGCCGC
GGTTATCTGAATTCGGTGGTGGCGCTGTCCGATCCCAAGATGCCCTATTACGCCAAGGACCACCTGGTGCCGTTCGGCGA
ATTCGTGCCGCTGCCGGGCCTGATAGGCTGGATCTACCAGCATATGGACATGCCGCTGTCCGGCTTTACCCGCGGCGGCG
CCGACCAGCCGCCGCTGACGCTGGCCGGACAGAAGGTGGCGTTCAACGTCTGCTACGAAGACAGCTTCGGCGAAGAGCTG
ATCGGCCCGGCGTCGCGCGCCGGCATGCTGGCCAACGTCAGCAATCTGGCCTGGTTCGGCAAGAGCGAGGCGATGAGCCA
GCACCTGCAACTGTCGCAGGCGCGCTCGCTGGAAACCGGCCGCTACATGCTGCGCGCCACCAACAACGGCATGACCGCCA
TCATCCGTCCGGACGGCGAGATTTCCGCGGTGGCCGCGCCGTTCACCGCCCAGGTGCTGACCGGCTTCGCCCAAAGCAGG
CAGGGACTGACGCCGTACATGCGGTTCGGCAATCTGCCCGTCGTCTTAGGCTGCGGCGCCCTGCTGCTGCTGGCCCTGCT
GCTGGGCTGGCGCCGGCGAGGCCAGCATTAG

Upstream 100 bases:

>100_bases
GCCGGCCTGCGCTTCACCGTGCTGCGCGCCGACAGCCGCCGCCTGGACACCTTGCTGGTGGAACGCATCCAGGCCTCCAT
CGACATCGCCGAATAAGGCT

Downstream 100 bases:

>100_bases
CCCTGGCTGGCATTGAACAAGAAAAAGGCCCGGCGATGCGCACCGCCGGGCCTTTTTCCATTTCCGGCGCTGAGCTAGCC
GCGTACCGAGAAACGCGACA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVELLQREPRRAFWLGYAWGLGAY
VSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLASWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWG
AAGYSQITESPLAGYAPLGGIHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVAL
AQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGEASRAGMALASGIPRRTDDGR
GYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQHMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEEL
IGPASRAGMLANVSNLAWFGKSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSR
QGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH

Sequences:

>Translated_516_residues
MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVELLQREPRRAFWLGYAWGLGAY
VSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLASWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWG
AAGYSQITESPLAGYAPLGGIHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVAL
AQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGEASRAGMALASGIPRRTDDGR
GYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQHMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEEL
IGPASRAGMLANVSNLAWFGKSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSR
QGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH
>Mature_516_residues
MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVELLQREPRRAFWLGYAWGLGAY
VSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLASWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWG
AAGYSQITESPLAGYAPLGGIHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVAL
AQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGEASRAGMALASGIPRRTDDGR
GYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQHMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEEL
IGPASRAGMLANVSNLAWFGKSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSR
QGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=509, Percent_Identity=38.1139489194499, Blast_Score=288, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_CHRVO (Q7NQI3)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903824.1
- ProteinModelPortal:   Q7NQI3
- GeneID:   2549739
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_4154
- NMPDR:   fig|243365.1.peg.4154
- HOGENOM:   HBG616234
- OMA:   CYESAFP
- PhylomeDB:   Q7NQI3
- ProtClustDB:   PRK00302
- BioCyc:   CVIO243365:CV_4154-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 55969; Mature: 55969

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11f64358)-; HASH(0x13dfa728)-; HASH(0x134e5fa0)-; HASH(0x10b81770)-; HASH(0x14372a4c)-; HASH(0x11fb1a58)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVEL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQREPRRAFWLGYAWGLGAYVSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLA
HHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWGAAGYSQITESPLAGYAPLGG
HHHEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCH
IHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEE
AQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGE
ECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCHHHHHHHHCC
ASRAGMALASGIPRRTDDGRGYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQ
HHHHHHHHHCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
HMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEELIGPASRAGMLANVSNLAWFG
HHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHCCCHHHCCHHHHHHHHHHCC
KSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSR
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCEEEEECHHHHHHHHHHHHHC
QGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MLNAAGGAGCDPSSPTATSPMRILILLLAAALAGAFTLFAFAPYRLFWLMPLCLAALVEL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQREPRRAFWLGYAWGLGAYVSNFRWIYDSLHDVAGLPAWIAAPLVLLLPAYLALYPGLA
HHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
SWLACRIDPRPGVRWLLAFPAAWELGEWLRGWVMTGFPWGAAGYSQITESPLAGYAPLGG
HHHEEECCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCH
IHLVNYLVALSAAALAMLARAGMRQRIGILIAAALAWGSGVWLRDIEWTTPAGKPITVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEE
AQGNIAQELKWSPENLENSLLTYYRQVAMTRADLMILPETALPLFLDDLPSGYLSMMRGE
ECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHCCHHHHHHHHCC
ASRAGMALASGIPRRTDDGRGYLNSVVALSDPKMPYYAKDHLVPFGEFVPLPGLIGWIYQ
HHHHHHHHHCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
HMDMPLSGFTRGGADQPPLTLAGQKVAFNVCYEDSFGEELIGPASRAGMLANVSNLAWFG
HHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHCCCHHHCCHHHHHHHHHHCC
KSEAMSQHLQLSQARSLETGRYMLRATNNGMTAIIRPDGEISAVAAPFTAQVLTGFAQSR
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCEEEEECHHHHHHHHHHHHHC
QGLTPYMRFGNLPVVLGCGALLLLALLLGWRRRGQH
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782