| Definition | Chromobacterium violaceum ATCC 12472 chromosome, complete genome. |
|---|---|
| Accession | NC_005085 |
| Length | 4,751,080 |
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The map label for this gene is fabG [H]
Identifier: 34499402
GI number: 34499402
Start: 4268204
End: 4268968
Strand: Reverse
Name: fabG [H]
Synonym: CV_3947
Alternate gene names: 34499402
Gene position: 4268968-4268204 (Counterclockwise)
Preceding gene: 34499403
Following gene: 34499401
Centisome position: 89.85
GC content: 71.76
Gene sequence:
>765_bases CTGCCGCTCGCCTTGCGCAAGGCGGCGCTGGTGACCGGGGCGGGGCGGGGCATAGGCCGCGCGATCGCGCTGGAGCTGGC CGGCCGCAAGCTGCCGGTCTTCGTCAACTATCGCAGCGACGCCAAGGCGGCCGAGGATGCTTGCGCGGCGATCCGGGCCG GCGGCGGCGAGGCCTATCCGGTTGGCGCCGACGTGTCCGACCGCGACGCGGTGGCGGCGATGTTCGCCGACATCCGCCAG CGCGGCTTCTGGGTGCAGACTCTGGTCAACAACGCCGGCATCGTCCGCGACGGCCTGTTGGCGATGATGCCGGCCGACGA CTGGAGCGCGGTGCTGGGCAGCAATCTGGACGGCAGCTTCCACTGCGCGCGCGCCGCGCTGCAGACCATGATGAGCCGCA AGAGCGGGCAGATCGTCAACATCGCCTCGGTCGGCGGCATGCGGGCCCAGGTCGGCCAGGCCAATTACGCGGCGGCCAAG GCCGGCCTCTTGGCGCTGACCCGCGGGCTGGCGCGCGAGGTCGGCCGCTACGGCATACGCGTCAACGCGGTGGCGCCGGG TTTCATCGACACCGACATGTTGGCGCAGATGAAGGCGTCGGACAAGGGCGCGGCCTTGCTGGAGGACGCGCGCGCCAGGC AGATCCCGCTGGCGCGCTTCGGCAGGCCGGAGGAGGTGGCGCAGACCGTCGGCTTCCTGTGCTCGGGCGCGGCCAGCTAT ATCACCGGCCATGTGCTGGTCGTCGACGGAGGGCTGTGTGCCTGA
Upstream 100 bases:
>100_bases CGCCTTCTGCGCGCTGGGGCTGCGCCGATGAGCGTCATCATTTCCGCGCTGCGCGCTGGGAAGCGGCGGCCATATGGAGA ATCCGATGAGTGAACACGCA
Downstream 100 bases:
>100_bases AGCCAGACCCTTGCTCGGCCGGCTGTTCTCGCCCATCCGCCTGAACCGGCTGCGGCTGCCCAACCGGCTGCTGATGAGCT CGATGCACCTCAACCTGGAC
Product: 3-oxoacyl-ACP reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MPLALRKAALVTGAGRGIGRAIALELAGRKLPVFVNYRSDAKAAEDACAAIRAGGGEAYPVGADVSDRDAVAAMFADIRQ RGFWVQTLVNNAGIVRDGLLAMMPADDWSAVLGSNLDGSFHCARAALQTMMSRKSGQIVNIASVGGMRAQVGQANYAAAK AGLLALTRGLAREVGRYGIRVNAVAPGFIDTDMLAQMKASDKGAALLEDARARQIPLARFGRPEEVAQTVGFLCSGAASY ITGHVLVVDGGLCA
Sequences:
>Translated_254_residues MPLALRKAALVTGAGRGIGRAIALELAGRKLPVFVNYRSDAKAAEDACAAIRAGGGEAYPVGADVSDRDAVAAMFADIRQ RGFWVQTLVNNAGIVRDGLLAMMPADDWSAVLGSNLDGSFHCARAALQTMMSRKSGQIVNIASVGGMRAQVGQANYAAAK AGLLALTRGLAREVGRYGIRVNAVAPGFIDTDMLAQMKASDKGAALLEDARARQIPLARFGRPEEVAQTVGFLCSGAASY ITGHVLVVDGGLCA >Mature_253_residues PLALRKAALVTGAGRGIGRAIALELAGRKLPVFVNYRSDAKAAEDACAAIRAGGGEAYPVGADVSDRDAVAAMFADIRQR GFWVQTLVNNAGIVRDGLLAMMPADDWSAVLGSNLDGSFHCARAALQTMMSRKSGQIVNIASVGGMRAQVGQANYAAAKA GLLALTRGLAREVGRYGIRVNAVAPGFIDTDMLAQMKASDKGAALLEDARARQIPLARFGRPEEVAQTVGFLCSGAASYI TGHVLVVDGGLCA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=42.3387096774194, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=41.4728682170543, Blast_Score=150, Evalue=8e-37, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=33.8645418326693, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI4504505, Length=236, Percent_Identity=35.1694915254237, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=6e-21, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=30.6451612903226, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=32.9317269076305, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=29.7872340425532, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=30.5263157894737, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=29.8387096774194, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI25282469, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI20149619, Length=236, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4758504, Length=266, Percent_Identity=29.3233082706767, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=29.5880149812734, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=209, Percent_Identity=28.7081339712919, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.3877551020408, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI209862901, Length=220, Percent_Identity=28.1818181818182, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI19923983, Length=220, Percent_Identity=28.1818181818182, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI19743808, Length=210, Percent_Identity=29.5238095238095, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI7657478, Length=202, Percent_Identity=28.7128712871287, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI4504503, Length=211, Percent_Identity=26.5402843601896, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=31.7460317460317, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=43.1451612903226, Blast_Score=173, Evalue=1e-44, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=41.1290322580645, Blast_Score=150, Evalue=5e-38, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=37.6984126984127, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=35.3413654618474, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=31.7269076305221, Blast_Score=127, Evalue=5e-31, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=34.3629343629344, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=30, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=31.0204081632653, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.4677419354839, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=34.5381526104418, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.4573643410853, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=232, Percent_Identity=27.1551724137931, Blast_Score=71, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=37.7952755905512, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=35.6275303643725, Blast_Score=134, Evalue=5e-32, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=31.3253012048193, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=33.2, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=35.1063829787234, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=31.4516129032258, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=30.1526717557252, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=30.5882352941176, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.8625954198473, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=30.3643724696356, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=31.3725490196078, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=30.3664921465969, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=30.3501945525292, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=29.5019157088123, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=29.6153846153846, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562906, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.9433962264151, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=28.1853281853282, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.277566539924, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.5171102661597, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562908, Length=257, Percent_Identity=29.1828793774319, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=29.5719844357977, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17561272, Length=216, Percent_Identity=28.7037037037037, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997099, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=25.5208333333333, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193203117, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=36.7021276595745, Blast_Score=110, Evalue=2e-25, Organism=Saccharomyces cerevisiae, GI6324126, Length=154, Percent_Identity=38.3116883116883, Blast_Score=88, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=39.7590361445783, Blast_Score=156, Evalue=1e-38, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=34.2741935483871, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=32.520325203252, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI18859837, Length=250, Percent_Identity=33.2, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=31.5789473684211, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24644337, Length=198, Percent_Identity=32.8282828282828, Blast_Score=91, Evalue=5e-19, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI24648944, Length=199, Percent_Identity=30.6532663316583, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=30.622009569378, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI281364892, Length=201, Percent_Identity=27.363184079602, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24640442, Length=201, Percent_Identity=30.8457711442786, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24584752, Length=228, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24640492, Length=192, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007236, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24641388, Length=254, Percent_Identity=27.5590551181102, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24586328, Length=205, Percent_Identity=24.8780487804878, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI22024069, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26333; Mature: 26201
Theoretical pI: Translated: 9.53; Mature: 9.53
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 5.1 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPLALRKAALVTGAGRGIGRAIALELAGRKLPVFVNYRSDAKAAEDACAAIRAGGGEAYP CCCHHHHHHHHCCCCCCCCHHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEE VGADVSDRDAVAAMFADIRQRGFWVQTLVNNAGIVRDGLLAMMPADDWSAVLGSNLDGSF CCCCCCCHHHHHHHHHHHHHCCEEHHHHHCCCCCHHCCEEEEECCCCHHHHHCCCCCCCH HCARAALQTMMSRKSGQIVNIASVGGMRAQVGQANYAAAKAGLLALTRGLAREVGRYGIR HHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEE VNAVAPGFIDTDMLAQMKASDKGAALLEDARARQIPLARFGRPEEVAQTVGFLCSGAASY EEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCHHHH ITGHVLVVDGGLCA HCCEEEEECCCCCC >Mature Secondary Structure PLALRKAALVTGAGRGIGRAIALELAGRKLPVFVNYRSDAKAAEDACAAIRAGGGEAYP CCHHHHHHHHCCCCCCCCHHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEE VGADVSDRDAVAAMFADIRQRGFWVQTLVNNAGIVRDGLLAMMPADDWSAVLGSNLDGSF CCCCCCCHHHHHHHHHHHHHCCEEHHHHHCCCCCHHCCEEEEECCCCHHHHHCCCCCCCH HCARAALQTMMSRKSGQIVNIASVGGMRAQVGQANYAAAKAGLLALTRGLAREVGRYGIR HHHHHHHHHHHHCCCCCEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEE VNAVAPGFIDTDMLAQMKASDKGAALLEDARARQIPLARFGRPEEVAQTVGFLCSGAASY EEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCHHHH ITGHVLVVDGGLCA HCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]