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The map label for this gene is etfA [H]

Identifier: 34499272

GI number: 34499272

Start: 4116734

End: 4117666

Strand: Reverse

Name: etfA [H]

Synonym: CV_3817

Alternate gene names: 34499272

Gene position: 4117666-4116734 (Counterclockwise)

Preceding gene: 34499273

Following gene: 34499271

Centisome position: 86.67

GC content: 67.63

Gene sequence:

>933_bases
ATGGCTATTCTCGTTATCGCTGAACACGACAACCAGAGCCTGAAGGCAGGCACCCTGAACACCATCACCGCCGCGGCCAA
GCTGGGCGAAGTGCATGTGCTGGTGGCCGGCCACAACGCCGACGCCGCCGCCGACGCCGCCAAGAGCGTGGCCGGCGTGG
CCAAGGTGCTGCTGGCCGACGCCGCCCACTATGCGCACGGTCTGGCCGAAAGCCTGTCCGCGCTGATCGTCGGCCTGGCC
AAGGGCTATAGCCACGTGCTGGCCCCGGCTTCGTCCTTCGGCAAGAATCTGCTGCCGCGCGTCGCCGCGTTGCTGGACGT
CGCTCAGATTTCCGAAATCGTCGCCATCGAATCCGCCGACACCTTCGTGCGCCCGGTCTACGCCGGTAACGTGCTGGCCA
CCGTGCAGTCGGCCGATGCCATCAAGGTGATCACCGTGCGTACCACCGCCTTCGACGCGGCGGGCCAGGGCGGTTCGGCC
GCGGTGGAAACCATCGCCGCCGGCGCCGACAGCCAGCTGTCCGCCTTCGTCGGCCAGGAACTGACCAAGTCCGACCGCCC
GGAACTGGGCTCGGCCAAGGTGATCGTGTCCGGCGGCCGCGCATTGGGCTCGGAAGAGCAGTTCAAGGCGGTGATCGGCC
CGCTGGCCGACAAGCTGTCCGCCGCCGTCGGCGCCTCGCGCGCCGCGGTCGACGCTGGCTACGCGCCGAACGACTACCAG
GTCGGCCAGACCGGCAAGGTGGTGGCACCGCAGCTGTACTTCGCCGTCGGCATCTCCGGCGCGATCCAGCACCTGGCGGG
CATGAAGGACTCCAAGGTGATCGTCGCCATCAACAAGGACGAGGAAGCTCCGATCTTCCAGGTGGCCGACTACGGCATCG
TCGGCGACCTGTTCACCGTGGTGCCGGAGCTGATCGCCGAACTGTCGAAGTAA

Upstream 100 bases:

>100_bases
GAAAGTGGCCGAACCGGCCAAGCGTTCCGCCGGCATCAAGGTGGCCAACGCCGCCGAACTGGTCGCCAAACTCAAGAACG
AAGCAAAGGTGCTGTAAGAC

Downstream 100 bases:

>100_bases
GCGGCAGCCGGGGGCGCGGCCGCAAGCGCCCCCGACCGAGCAGGCAGCATAGCCGCCGGAATCAACAACAGCAGCCGGCG
CCCAGAGTTGAGCGCCGGTT

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAILVIAEHDNQSLKAGTLNTITAAAKLGEVHVLVAGHNADAAADAAKSVAGVAKVLLADAAHYAHGLAESLSALIVGLA
KGYSHVLAPASSFGKNLLPRVAALLDVAQISEIVAIESADTFVRPVYAGNVLATVQSADAIKVITVRTTAFDAAGQGGSA
AVETIAAGADSQLSAFVGQELTKSDRPELGSAKVIVSGGRALGSEEQFKAVIGPLADKLSAAVGASRAAVDAGYAPNDYQ
VGQTGKVVAPQLYFAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGIVGDLFTVVPELIAELSK

Sequences:

>Translated_310_residues
MAILVIAEHDNQSLKAGTLNTITAAAKLGEVHVLVAGHNADAAADAAKSVAGVAKVLLADAAHYAHGLAESLSALIVGLA
KGYSHVLAPASSFGKNLLPRVAALLDVAQISEIVAIESADTFVRPVYAGNVLATVQSADAIKVITVRTTAFDAAGQGGSA
AVETIAAGADSQLSAFVGQELTKSDRPELGSAKVIVSGGRALGSEEQFKAVIGPLADKLSAAVGASRAAVDAGYAPNDYQ
VGQTGKVVAPQLYFAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGIVGDLFTVVPELIAELSK
>Mature_309_residues
AILVIAEHDNQSLKAGTLNTITAAAKLGEVHVLVAGHNADAAADAAKSVAGVAKVLLADAAHYAHGLAESLSALIVGLAK
GYSHVLAPASSFGKNLLPRVAALLDVAQISEIVAIESADTFVRPVYAGNVLATVQSADAIKVITVRTTAFDAAGQGGSAA
VETIAAGADSQLSAFVGQELTKSDRPELGSAKVIVSGGRALGSEEQFKAVIGPLADKLSAAVGASRAAVDAGYAPNDYQV
GQTGKVVAPQLYFAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGIVGDLFTVVPELIAELSK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=63.0225080385852, Blast_Score=357, Evalue=5e-99,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=63.4686346863469, Blast_Score=317, Evalue=8e-87,
Organism=Escherichia coli, GI1787990, Length=260, Percent_Identity=31.9230769230769, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786226, Length=235, Percent_Identity=34.468085106383, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87082157, Length=236, Percent_Identity=33.0508474576271, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=57.0512820512821, Blast_Score=323, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6325261, Length=289, Percent_Identity=47.7508650519031, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI17136898, Length=310, Percent_Identity=63.2258064516129, Blast_Score=353, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24652801, Length=310, Percent_Identity=63.2258064516129, Blast_Score=353, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31373; Mature: 31242

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVIAEHDNQSLKAGTLNTITAAAKLGEVHVLVAGHNADAAADAAKSVAGVAKVLLAD
CEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
AAHYAHGLAESLSALIVGLAKGYSHVLAPASSFGKNLLPRVAALLDVAQISEIVAIESAD
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
TFVRPVYAGNVLATVQSADAIKVITVRTTAFDAAGQGGSAAVETIAAGADSQLSAFVGQE
HHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHH
LTKSDRPELGSAKVIVSGGRALGSEEQFKAVIGPLADKLSAAVGASRAAVDAGYAPNDYQ
HHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPQLYFAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGIVGDLFTV
CCCCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHH
VPELIAELSK
HHHHHHHHCC
>Mature Secondary Structure 
AILVIAEHDNQSLKAGTLNTITAAAKLGEVHVLVAGHNADAAADAAKSVAGVAKVLLAD
EEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
AAHYAHGLAESLSALIVGLAKGYSHVLAPASSFGKNLLPRVAALLDVAQISEIVAIESAD
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
TFVRPVYAGNVLATVQSADAIKVITVRTTAFDAAGQGGSAAVETIAAGADSQLSAFVGQE
HHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHH
LTKSDRPELGSAKVIVSGGRALGSEEQFKAVIGPLADKLSAAVGASRAAVDAGYAPNDYQ
HHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
VGQTGKVVAPQLYFAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGIVGDLFTV
CCCCCCEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHH
VPELIAELSK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]