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The map label for this gene is deoD

Identifier: 34499153

GI number: 34499153

Start: 3996735

End: 3997445

Strand: Reverse

Name: deoD

Synonym: CV_3698

Alternate gene names: 34499153

Gene position: 3997445-3996735 (Counterclockwise)

Preceding gene: 34499154

Following gene: 34499152

Centisome position: 84.14

GC content: 64.84

Gene sequence:

>711_bases
ATGGCAACCCCGCATATCAACGCCAAAGACGGCGCCTTCGCCGAAACCGTACTGATGCCGGGCGACCCGCTGCGCGCTCA
GCTGATCGCCGAGACCTTCCTGGAGGGCGCCGAGCTGGTGACCAACGTGCGCAACGTGTTCGGTTACACCGGCACCTACA
AGGGCAAGCGCCTGTCGGTGATGGCGCACGGCATGGGCATCCCGTCGGCCAGCATCTACACCACCGAGCTGATCAAGGAC
TACGGCGTCAAGAACATCATCCGCATTGGCTCCTGCGGCGCGGTGACGCCGGACATCAAGCTGCGCGAGCTGTTCGTCGC
CATGGGCGCGTCCACCGACAGCAAGGTGAACCGCATGCGCTTCAACGACCACGACTACGCCGCCATCGCCGATTACACGC
TGCTGCGCACCGTGGTGGACACCGCCGCCGAGCAGGGCAAGAAGGTGACCGTGGGCAATGTGTTCTCCGCCGACCTGTTC
TACGGCGTGCAGCCGAACATGCTGGACGTGCTCTCCAAGCTGCAGGTCAACGTGATCGAGATGGAGCTGGCGGGCATCTA
CAGCGTGGCCGCCCAGTACGGCGCGCGCGCGGTCGGCATCCTGACCGTGTCCGACATCATCCCGACCGGCGAGGCCACCA
GCGCCGAGGAGCGCCAGACTTCGTTCCGCGACATGATGGAAGTGGCGCTGGACGCTGCGATCAAGCTGTAA

Upstream 100 bases:

>100_bases
GACTGAGGCCGCCACCCCGGGCCGCCGCGCGCGGCCCGGCGTCGTTTTTCCCCGCTTGCGCAAGCGCAGCGGGAGCAGAA
TCATTTAGAGGAGACCTTGA

Downstream 100 bases:

>100_bases
GTCACTGAAAAAGCTGGATAAGTGGACGCCTTTCGGCGTCCGTTTCCGCATTGCGGAACCGGGTGTGGCATGCGCGCACA
TCGTTTATCGTGCAGTGCAC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAKDGAFAETVLMPGDPLRAQLIAETFLEGAELVTNVRNVFGYTGTYKGKRLSVMAHGMGIPSASIYTTELIKD
YGVKNIIRIGSCGAVTPDIKLRELFVAMGASTDSKVNRMRFNDHDYAAIADYTLLRTVVDTAAEQGKKVTVGNVFSADLF
YGVQPNMLDVLSKLQVNVIEMELAGIYSVAAQYGARAVGILTVSDIIPTGEATSAEERQTSFRDMMEVALDAAIKL

Sequences:

>Translated_236_residues
MATPHINAKDGAFAETVLMPGDPLRAQLIAETFLEGAELVTNVRNVFGYTGTYKGKRLSVMAHGMGIPSASIYTTELIKD
YGVKNIIRIGSCGAVTPDIKLRELFVAMGASTDSKVNRMRFNDHDYAAIADYTLLRTVVDTAAEQGKKVTVGNVFSADLF
YGVQPNMLDVLSKLQVNVIEMELAGIYSVAAQYGARAVGILTVSDIIPTGEATSAEERQTSFRDMMEVALDAAIKL
>Mature_235_residues
ATPHINAKDGAFAETVLMPGDPLRAQLIAETFLEGAELVTNVRNVFGYTGTYKGKRLSVMAHGMGIPSASIYTTELIKDY
GVKNIIRIGSCGAVTPDIKLRELFVAMGASTDSKVNRMRFNDHDYAAIADYTLLRTVVDTAAEQGKKVTVGNVFSADLFY
GVQPNMLDVLSKLQVNVIEMELAGIYSVAAQYGARAVGILTVSDIIPTGEATSAEERQTSFRDMMEVALDAAIKL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=61.965811965812, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1790265, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_CHRVO (Q7NRT2)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903368.1
- ProteinModelPortal:   Q7NRT2
- SMR:   Q7NRT2
- GeneID:   2548217
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3698
- NMPDR:   fig|243365.1.peg.3698
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- PhylomeDB:   Q7NRT2
- BioCyc:   CVIO243365:CV_3698-MONOMER
- BRENDA:   2.4.2.1
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25465; Mature: 25333

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAKDGAFAETVLMPGDPLRAQLIAETFLEGAELVTNVRNVFGYTGTYKGKRLSV
CCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MAHGMGIPSASIYTTELIKDYGVKNIIRIGSCGAVTPDIKLRELFVAMGASTDSKVNRMR
EEECCCCCCCHHHHHHHHHHHCHHHHEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHCC
FNDHDYAAIADYTLLRTVVDTAAEQGKKVTVGNVFSADLFYGVQPNMLDVLSKLQVNVIE
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEHHEEECCCCCHHHHHHHHHHHHEE
MELAGIYSVAAQYGARAVGILTVSDIIPTGEATSAEERQTSFRDMMEVALDAAIKL
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPHINAKDGAFAETVLMPGDPLRAQLIAETFLEGAELVTNVRNVFGYTGTYKGKRLSV
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MAHGMGIPSASIYTTELIKDYGVKNIIRIGSCGAVTPDIKLRELFVAMGASTDSKVNRMR
EEECCCCCCCHHHHHHHHHHHCHHHHEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHCC
FNDHDYAAIADYTLLRTVVDTAAEQGKKVTVGNVFSADLFYGVQPNMLDVLSKLQVNVIE
CCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEHHEEECCCCCHHHHHHHHHHHHEE
MELAGIYSVAAQYGARAVGILTVSDIIPTGEATSAEERQTSFRDMMEVALDAAIKL
HHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782