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The map label for this gene is surE

Identifier: 34499134

GI number: 34499134

Start: 3980507

End: 3981250

Strand: Direct

Name: surE

Synonym: CV_3679

Alternate gene names: 34499134

Gene position: 3980507-3981250 (Clockwise)

Preceding gene: 34499133

Following gene: 34499135

Centisome position: 83.78

GC content: 66.26

Gene sequence:

>744_bases
ATGAAGTTTCTGCTCAGCAACGACGACGGTTATTTCGCGCCTGGACTAGCCATGCTGGCCCAGACGCTGCAACGCTACGG
CGAGGTGGTGGTGGTGGCGCCGGAACGCGACCGCAGCGGCGCCAGCAACTCTCTGACGCTGGATAGGCCGCTGACGGTGC
GCAAGGCCGCCAACGGCTTTCATTATGTCAACGGCACGCCGACCGACTGCGTCCACCTCGCGGTCACCGGCTTCCTGGAT
TTCAGGCCGAACATGATCTTCACCGGCATCAACCATGGCCCGAACATGGGCGACGACACGCTGTACTCCGGCACCGTCGC
CGCCGCCACCGAGGGCTTCATGCTGGGCATTCCCTCCGTCGCGGTCTCGCTGGCCGGCCACAGCGGCAAGCATTTCGCCA
GCGCCGGCAAGGTGGTGGAGCAACTGGTCGAGCGCTGCCTGGAGGAGCCGTTCCAGCAGCCGGTCCTGCTCAACGTCAAC
GTGCCGGACGCGCCGCCGGAAGAAGTGGGCGCGCTCCAAGTCACCCGGCTGGGACGGCGCCACGCCGCCCAGCCGGTGAT
CAAATCTCAGAATCCGCGCGGCGAGACGATATACTGGGTAGGACCGGTCGGCGCGGTGCAGGATGCCGGCGCCGGCACCG
ACTTCGGCTGCGTCGCGTCCAAGCAGGTGTCCGTCACGCCGCTGATGCTGGATCTGACCGCCTACGGGCAACTGGACAGG
ATTTCCACATGGCTGCACCGCTGA

Upstream 100 bases:

>100_bases
CCGCCCTCCGCGGGTTTTTTTACGGTCCCCGCGCCCACGCCGCGCTATCCGCCGTCATGCCGGCGGCGCTACAATCGGGC
GACATTCACGGAAAGACAGT

Downstream 100 bases:

>100_bases
CCCCGAACGCCCAGGCCTACGGCATGCTTTCCGAGCGCACGCGCCGCCGCATGAGCGACCGCCTGCGCCAGCACGGCATC
AGCGACGAGCGGGTGCTGTC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGFHYVNGTPTDCVHLAVTGFLD
FRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSVAVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVN
VPDAPPEEVGALQVTRLGRRHAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDR
ISTWLHR

Sequences:

>Translated_247_residues
MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGFHYVNGTPTDCVHLAVTGFLD
FRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSVAVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVN
VPDAPPEEVGALQVTRLGRRHAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDR
ISTWLHR
>Mature_247_residues
MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGFHYVNGTPTDCVHLAVTGFLD
FRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSVAVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVN
VPDAPPEEVGALQVTRLGRRHAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDR
ISTWLHR

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=247, Percent_Identity=51.0121457489879, Blast_Score=248, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_CHRVO (Q7NRV1)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903349.1
- ProteinModelPortal:   Q7NRV1
- SMR:   Q7NRV1
- GeneID:   2548856
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3679
- NMPDR:   fig|243365.1.peg.3679
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q7NRV1
- ProtClustDB:   PRK00346
- BioCyc:   CVIO243365:CV_3679-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26443; Mature: 26443

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGF
CEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEECCCEEEEECCCCE
HYVNGTPTDCVHLAVTGFLDFRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSV
EEECCCCCHHEEEEEHHHEECCCCEEEEECCCCCCCCCCCEECCCHHHHCCCEEEECCHH
AVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVNVPDAPPEEVGALQVTRLGRR
HHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHHHHHHHH
HAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDR
HHCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCEECEEEEEEHHCCCHHH
ISTWLHR
HHHHHCC
>Mature Secondary Structure
MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGF
CEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEECCCEEEEECCCCE
HYVNGTPTDCVHLAVTGFLDFRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSV
EEECCCCCHHEEEEEHHHEECCCCEEEEECCCCCCCCCCCEECCCHHHHCCCEEEECCHH
AVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVNVPDAPPEEVGALQVTRLGRR
HHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHHHHHHHH
HAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDR
HHCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCCCEECEEEEEEHHCCCHHH
ISTWLHR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782