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The map label for this gene is paaK [H]

Identifier: 34499053

GI number: 34499053

Start: 3904978

End: 3906285

Strand: Reverse

Name: paaK [H]

Synonym: CV_3598

Alternate gene names: 34499053

Gene position: 3906285-3904978 (Counterclockwise)

Preceding gene: 34499054

Following gene: 34499052

Centisome position: 82.22

GC content: 67.66

Gene sequence:

>1308_bases
CTGATCATCCGTCCAACGAGGAAACCAACCATGTTGCCTGTAGCAAGGATTGCTCGCGTCGTCGAGCAGGCGTCGCTGCG
TCCGCACTACCCGCGCCATTGGGGCGTGGAGCGGGAGCAGATCATGCAATGGCTGCGCGACGGCGAGTATCACCGCGTGC
CCGCGATCCGCAAGCAGGATCTGTCCAACCATTGGGACGAGCTGATGGAGTACGGCGACTTCACCGATGTCGTCAGCTCT
TCCGGGACCACCGGACGGCCGGTGGAACTGCCGGTGCACCGGCTGCAGGAAATGGTGTGGGTCGATTGCGTGGCGCGGGT
GCTCACCGAGCTGGGCGCGAAGCCGGGCGACCGCATGCTGCATCTGCTCAGCAACAACGACATGTTCACGCTGGGGCCGC
TGGTGCTGCAGGCGGCCAAGAAGGTGGGTCTGGGGCCGTTCCGCTGCTCGCCGCAGCGCACGCGGCGCATCCTGGACGTG
GTGCATTACCACCAGCCGGCCTTCGTGGTCGGCAATCCGGCTGTGATGCTGGAGCTGGCGCAGACCATGGGCGCGGATTT
CCCGGCGCCGGAGTGTCTGCCGGATTACGCCTATTTCGGCGCCTGCGGCGCTTTCGACGCCGACAACCGGCCGACGCCGG
TGGCGCGCAAGGTGATGGAGCTGTGGGGGCTGAAGGAGGCGCTCAACGAGTACGGCTGCAGCGAACTGGGTTCGGTCGGC
CATGAGTGCCTGCAGCATCGCGGCTTCCACATCAACGACGATGCGGTCCACGTCGAGCTGATCGATCCCGATACCGGCCT
GCCGGCCGCGCCGGGCCAGCCGGGCGAGGTGGTGGTCACCTCGCTGACCTTGCCGCGCGGCTTCATCGCGGTGCGCTACG
CGACCGGCGACATCGCCAGCTGGCTGGACGACAGCCCTTGCGACTGCGGCCGCCGCAGCCCGCGGCTGGGCGCCATCATC
GGCCGGGTCGACCACCAGTTGAAAATCCAGGGCCAGACGGTCTATCCGGATCTGATCTTCGACGTGCTGGGCGGCGTGGC
CGGCATAGACAACGAACTGGTGGTGCGCTGTCCGGACGAGCAGGGCGGCCAGCGGGTGGAGGTATGGCTGTCGGCGGGAG
ACGGCGGCGCCGACATCGTCCGCCGGGTCGGAGAACTGCTGTTGCAGCGGCTGGCGGTGGCGCCGCCGCTGCGCCTGGTG
CCGTCCGAGCTGATCCAGAAGCTGAAGCGCGACAAGATGGCCAGCGGCAACGGCGTCAAGGTGCCGCGCTTCATCGAGCT
GCCGCTGCCCGTCCATGCCTACCTATGA

Upstream 100 bases:

>100_bases
CCGCTGCGCCGCGCCAGCGAGCGCTATCTGAACAGCCGCCTGGGGCCCGCCATGACTTAGCGGCCGCTGCGGCGTCGTGT
CCGGCCCGAGGGGCCGGCGT

Downstream 100 bases:

>100_bases
GGGATGCGCGATGACCCCCTTGTTGCAGGCGCCGCGTCTGATGCCCGGCCTGAGCCTGAAGCTCGAATACCTGAATCCCT
CGCTGTCGATCAAGCACCGT

Product: coenzyme F390 synthetase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MIIRPTRKPTMLPVARIARVVEQASLRPHYPRHWGVEREQIMQWLRDGEYHRVPAIRKQDLSNHWDELMEYGDFTDVVSS
SGTTGRPVELPVHRLQEMVWVDCVARVLTELGAKPGDRMLHLLSNNDMFTLGPLVLQAAKKVGLGPFRCSPQRTRRILDV
VHYHQPAFVVGNPAVMLELAQTMGADFPAPECLPDYAYFGACGAFDADNRPTPVARKVMELWGLKEALNEYGCSELGSVG
HECLQHRGFHINDDAVHVELIDPDTGLPAAPGQPGEVVVTSLTLPRGFIAVRYATGDIASWLDDSPCDCGRRSPRLGAII
GRVDHQLKIQGQTVYPDLIFDVLGGVAGIDNELVVRCPDEQGGQRVEVWLSAGDGGADIVRRVGELLLQRLAVAPPLRLV
PSELIQKLKRDKMASGNGVKVPRFIELPLPVHAYL

Sequences:

>Translated_435_residues
MIIRPTRKPTMLPVARIARVVEQASLRPHYPRHWGVEREQIMQWLRDGEYHRVPAIRKQDLSNHWDELMEYGDFTDVVSS
SGTTGRPVELPVHRLQEMVWVDCVARVLTELGAKPGDRMLHLLSNNDMFTLGPLVLQAAKKVGLGPFRCSPQRTRRILDV
VHYHQPAFVVGNPAVMLELAQTMGADFPAPECLPDYAYFGACGAFDADNRPTPVARKVMELWGLKEALNEYGCSELGSVG
HECLQHRGFHINDDAVHVELIDPDTGLPAAPGQPGEVVVTSLTLPRGFIAVRYATGDIASWLDDSPCDCGRRSPRLGAII
GRVDHQLKIQGQTVYPDLIFDVLGGVAGIDNELVVRCPDEQGGQRVEVWLSAGDGGADIVRRVGELLLQRLAVAPPLRLV
PSELIQKLKRDKMASGNGVKVPRFIELPLPVHAYL
>Mature_435_residues
MIIRPTRKPTMLPVARIARVVEQASLRPHYPRHWGVEREQIMQWLRDGEYHRVPAIRKQDLSNHWDELMEYGDFTDVVSS
SGTTGRPVELPVHRLQEMVWVDCVARVLTELGAKPGDRMLHLLSNNDMFTLGPLVLQAAKKVGLGPFRCSPQRTRRILDV
VHYHQPAFVVGNPAVMLELAQTMGADFPAPECLPDYAYFGACGAFDADNRPTPVARKVMELWGLKEALNEYGCSELGSVG
HECLQHRGFHINDDAVHVELIDPDTGLPAAPGQPGEVVVTSLTLPRGFIAVRYATGDIASWLDDSPCDCGRRSPRLGAII
GRVDHQLKIQGQTVYPDLIFDVLGGVAGIDNELVVRCPDEQGGQRVEVWLSAGDGGADIVRRVGELLLQRLAVAPPLRLV
PSELIQKLKRDKMASGNGVKVPRFIELPLPVHAYL

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=298, Percent_Identity=29.8657718120805, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48138; Mature: 48138

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRPTRKPTMLPVARIARVVEQASLRPHYPRHWGVEREQIMQWLRDGEYHRVPAIRKQD
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
LSNHWDELMEYGDFTDVVSSSGTTGRPVELPVHRLQEMVWVDCVARVLTELGAKPGDRML
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEE
HLLSNNDMFTLGPLVLQAAKKVGLGPFRCSPQRTRRILDVVHYHQPAFVVGNPAVMLELA
HHHCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
QTMGADFPAPECLPDYAYFGACGAFDADNRPTPVARKVMELWGLKEALNEYGCSELGSVG
HHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
HECLQHRGFHINDDAVHVELIDPDTGLPAAPGQPGEVVVTSLTLPRGFIAVRYATGDIAS
HHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHH
WLDDSPCDCGRRSPRLGAIIGRVDHQLKIQGQTVYPDLIFDVLGGVAGIDNELVVRCPDE
HCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCEECHHHHHHHHHHHCCCCCCEEEECCCC
QGGQRVEVWLSAGDGGADIVRRVGELLLQRLAVAPPLRLVPSELIQKLKRDKMASGNGVK
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHCCCCCCCC
VPRFIELPLPVHAYL
CCEEEECCCCHHCCC
>Mature Secondary Structure
MIIRPTRKPTMLPVARIARVVEQASLRPHYPRHWGVEREQIMQWLRDGEYHRVPAIRKQD
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
LSNHWDELMEYGDFTDVVSSSGTTGRPVELPVHRLQEMVWVDCVARVLTELGAKPGDRML
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHEE
HLLSNNDMFTLGPLVLQAAKKVGLGPFRCSPQRTRRILDVVHYHQPAFVVGNPAVMLELA
HHHCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
QTMGADFPAPECLPDYAYFGACGAFDADNRPTPVARKVMELWGLKEALNEYGCSELGSVG
HHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
HECLQHRGFHINDDAVHVELIDPDTGLPAAPGQPGEVVVTSLTLPRGFIAVRYATGDIAS
HHHHHHCCCEECCCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHH
WLDDSPCDCGRRSPRLGAIIGRVDHQLKIQGQTVYPDLIFDVLGGVAGIDNELVVRCPDE
HCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCEECHHHHHHHHHHHCCCCCCEEEECCCC
QGGQRVEVWLSAGDGGADIVRRVGELLLQRLAVAPPLRLVPSELIQKLKRDKMASGNGVK
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHCCCCCCCC
VPRFIELPLPVHAYL
CCEEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]