Click here to switch to the map view.

The map label for this gene is katE [H]

Identifier: 34499004

GI number: 34499004

Start: 3856911

End: 3858356

Strand: Direct

Name: katE [H]

Synonym: CV_3549

Alternate gene names: 34499004

Gene position: 3856911-3858356 (Clockwise)

Preceding gene: 34499003

Following gene: 34499005

Centisome position: 81.18

GC content: 65.77

Gene sequence:

>1446_bases
ATGAGAAAGCACACCCTCACCACCGCCGCCGGCGCGCCGGTCGTCGACAACCAGAACGTGCAGACCGCCGGCCCGCGCGG
CCCGATGCTGCTGCAAGATGTCTGGTATCTGGAAAAGCTGGCGCATTTCGACCGCGAGGTGATTCCGGAGCGCAGGATGC
ACGCCAAAGGCTCCGGCGCCTTCGGCACCTTCACCGTCACCCATGACATCACCCGTTACACCCGCGCCGCGCTGTTCTCC
GACATCGGCAAAAAGACCGACCTGTTCCTGCGCTTCTCCACCGTCGCCGGCGAGCGCGGCGCGGCCGACGCCGAGCGCGA
CATCCGCGGCTTCGCCGTCAAGTTCTACACCGAGGAGGGCAACTGGGACCTCGTAGGCAACAACACGCCGGTGTTCTTCC
TGCGCGACCCGCTGAAATTCCCCGACCTCAACCGCGCCGTGAAGCGCAATCCGTACACCAATATGCGCGACGCCAACGCC
AACTGGGACTTCTGGACGCTGCTGCCCGAGGCGCTGCACCAGGTCACCATCGTGATGAGCGACCGCGGCATACCGGCCAG
CTACCGCCACATGCACGGTTTCGGCAGCCACACCTTCAGCCTGATCAACGCCAAGGGCGAGCGCCACTGGGTCAAGTTCC
ATTTCCACACCCAGCAGGGCATCCGCAATCTGAGCGACGCCGAGGCGGAAAAGCTGGTGGGCCAAGACCGCGAAAGCGCG
CAGCGCGACCTGCTGGAGTGCATAGACCGCGGCGATTTCCCGCGCTGGACCCTGTACATCCAGGTGATGACAGAAGCCCA
GGCCGACGCTTGTCCCTTCAACCCCTTCGACCTGACCAAGGTGTGGTCGCACAAGGACTACCCGCTGATCGAGGTGGGCG
TGCTGGAGCTGAACCGCAATCCGCAGAACTACTTCGCAGACGTGGAGCAGGCCGCGTTCAATCCGGCCAACGTGGTGCCG
GGCATCAGCTTCTCGCCCGACCGCATGCTGCAGGGCCGCTTGTTCGCCTATGGCGACGCCGAGCGCTACCGCCTGGGCGT
CAATCACCATCTGATTCCGGTGAACGCGCCGCGCTGCCCCTTCCACAACAGCTACCACCGCGACGGCGCGATGCGGGTGG
ACAGCAACGCCGGCGCCACCATCGGCTACGAGCCGAACAGCCAGGGCAAGTGGCAGCAGCAGCCGGCATACGACGAGCCG
CCGCTGGCGCTGCAGGGCAACGCCTATCACTACGACTTCCGCGCGGACGACGACGATTACTACAGCCAGCCCGGCGCGCT
GTTCCGGCTGATGACGCCGGCCCAACAGCAAGCGCTGTTCGACAACACCGCACGCGCGATGGGCGGCGTCGACGAAGCGA
TCAAGCGCCGCCACATCGCCAACTGCGCCAAGGCCGATCCCGCCTATGGCGCGGGCGTGGCCAAGGCATTGGGCCTGAGC
GTCTGA

Upstream 100 bases:

>100_bases
AACAGAACTGGCATCACGCCTTGCTGGAAATGTGGTCGGGCTTCGCCTGGCTGCAATGAAATCCCTTCCGTCGATTCGCC
CCACTCAAGGAGAAAGCAGG

Downstream 100 bases:

>100_bases
CGCCGGCCTGATCCAGCCGGCGCGCCCGGGCCGCCGGCTTTTTTCTCCCCTCTTGATTTAAATGATAATCATTATCATTA
TTATGGAAAGACATCCCCGT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRKHTLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRYTRAALFS
DIGKKTDLFLRFSTVAGERGAADAERDIRGFAVKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNRAVKRNPYTNMRDANA
NWDFWTLLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSLINAKGERHWVKFHFHTQQGIRNLSDAEAEKLVGQDRESA
QRDLLECIDRGDFPRWTLYIQVMTEAQADACPFNPFDLTKVWSHKDYPLIEVGVLELNRNPQNYFADVEQAAFNPANVVP
GISFSPDRMLQGRLFAYGDAERYRLGVNHHLIPVNAPRCPFHNSYHRDGAMRVDSNAGATIGYEPNSQGKWQQQPAYDEP
PLALQGNAYHYDFRADDDDYYSQPGALFRLMTPAQQQALFDNTARAMGGVDEAIKRRHIANCAKADPAYGAGVAKALGLS
V

Sequences:

>Translated_481_residues
MRKHTLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRYTRAALFS
DIGKKTDLFLRFSTVAGERGAADAERDIRGFAVKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNRAVKRNPYTNMRDANA
NWDFWTLLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSLINAKGERHWVKFHFHTQQGIRNLSDAEAEKLVGQDRESA
QRDLLECIDRGDFPRWTLYIQVMTEAQADACPFNPFDLTKVWSHKDYPLIEVGVLELNRNPQNYFADVEQAAFNPANVVP
GISFSPDRMLQGRLFAYGDAERYRLGVNHHLIPVNAPRCPFHNSYHRDGAMRVDSNAGATIGYEPNSQGKWQQQPAYDEP
PLALQGNAYHYDFRADDDDYYSQPGALFRLMTPAQQQALFDNTARAMGGVDEAIKRRHIANCAKADPAYGAGVAKALGLS
V
>Mature_481_residues
MRKHTLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWYLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRYTRAALFS
DIGKKTDLFLRFSTVAGERGAADAERDIRGFAVKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNRAVKRNPYTNMRDANA
NWDFWTLLPEALHQVTIVMSDRGIPASYRHMHGFGSHTFSLINAKGERHWVKFHFHTQQGIRNLSDAEAEKLVGQDRESA
QRDLLECIDRGDFPRWTLYIQVMTEAQADACPFNPFDLTKVWSHKDYPLIEVGVLELNRNPQNYFADVEQAAFNPANVVP
GISFSPDRMLQGRLFAYGDAERYRLGVNHHLIPVNAPRCPFHNSYHRDGAMRVDSNAGATIGYEPNSQGKWQQQPAYDEP
PLALQGNAYHYDFRADDDDYYSQPGALFRLMTPAQQQALFDNTARAMGGVDEAIKRRHIANCAKADPAYGAGVAKALGLS
V

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=474, Percent_Identity=53.7974683544304, Blast_Score=513, Evalue=1e-145,
Organism=Escherichia coli, GI48994891, Length=497, Percent_Identity=43.2595573440644, Blast_Score=370, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=478, Percent_Identity=50.6276150627615, Blast_Score=483, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=50.1052631578947, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=49.685534591195, Blast_Score=474, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6320462, Length=487, Percent_Identity=46.4065708418891, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321525, Length=513, Percent_Identity=35.4775828460039, Blast_Score=308, Evalue=2e-84,
Organism=Drosophila melanogaster, GI17981717, Length=477, Percent_Identity=49.2662473794549, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=420, Percent_Identity=50.4761904761905, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54235; Mature: 54235

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHTLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWYLEKLAHFDREVIPERRMHAKGSGA
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
FGTFTVTHDITRYTRAALFSDIGKKTDLFLRFSTVAGERGAADAERDIRGFAVKFYTEEG
EEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHCCCEEEEEEEEECC
NWDLVGNNTPVFFLRDPLKFPDLNRAVKRNPYTNMRDANANWDFWTLLPEALHQVTIVMS
CEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEEE
DRGIPASYRHMHGFGSHTFSLINAKGERHWVKFHFHTQQGIRNLSDAEAEKLVGQDRESA
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHCCCHHHHHHHHHCCCHHHH
QRDLLECIDRGDFPRWTLYIQVMTEAQADACPFNPFDLTKVWSHKDYPLIEVGVLELNRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEECCC
PQNYFADVEQAAFNPANVVPGISFSPDRMLQGRLFAYGDAERYRLGVNHHLIPVNAPRCP
CHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCHHHEEECCCEEEEECCCCCCC
FHNSYHRDGAMRVDSNAGATIGYEPNSQGKWQQQPAYDEPPLALQGNAYHYDFRADDDDY
CCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCHH
YSQPGALFRLMTPAQQQALFDNTARAMGGVDEAIKRRHIANCAKADPAYGAGVAKALGLS
HCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
V
C
>Mature Secondary Structure
MRKHTLTTAAGAPVVDNQNVQTAGPRGPMLLQDVWYLEKLAHFDREVIPERRMHAKGSGA
CCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
FGTFTVTHDITRYTRAALFSDIGKKTDLFLRFSTVAGERGAADAERDIRGFAVKFYTEEG
EEEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHCCCEEEEEEEEECC
NWDLVGNNTPVFFLRDPLKFPDLNRAVKRNPYTNMRDANANWDFWTLLPEALHQVTIVMS
CEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEEE
DRGIPASYRHMHGFGSHTFSLINAKGERHWVKFHFHTQQGIRNLSDAEAEKLVGQDRESA
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHCCCHHHHHHHHHCCCHHHH
QRDLLECIDRGDFPRWTLYIQVMTEAQADACPFNPFDLTKVWSHKDYPLIEVGVLELNRN
HHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEECCC
PQNYFADVEQAAFNPANVVPGISFSPDRMLQGRLFAYGDAERYRLGVNHHLIPVNAPRCP
CHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCHHHEEECCCEEEEECCCCCCC
FHNSYHRDGAMRVDSNAGATIGYEPNSQGKWQQQPAYDEPPLALQGNAYHYDFRADDDDY
CCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCHH
YSQPGALFRLMTPAQQQALFDNTARAMGGVDEAIKRRHIANCAKADPAYGAGVAKALGLS
HCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA